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XR 5118 hydrochloride

Name: XR 5118 hydrochloride
Brand: Adooq Bioscience
SKU: A77012
Availability: OutOfStock

Cat. No. A77012 CAS 174766-49-5

PAI-1 Inhibitor

XR 5118 hydrochloride is a selective inhibitor of plasminogen activator inhibitor 1 (PAI-1), with an IC50 value of 12 µM. By binding to PAI-1, XR 5118 hydrochloride effectively reduces plasma PAI-1 activity, promoting endogenous thrombolysis and inhibiting thrombus formation. This compound is valuable for research applications related to cancer and thrombotic disorders, providing insights into mechanisms of fibrinolysis and clot regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	174766-49-5
Applications	PAI-1 Inhibitor
Formula	C₂₀H₂₂ClN₃O₂S₂
Molecular Weight	435.99
SMILES	O=C(/C(NC/1=O)=C/C2=CC=C(SCCN(C)C)S2)NC1=C/C3=CC=CC=C3.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.