Fig. 1 · Structure
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Diaplasinin
Cat. No.
A76997
CAS
481631-45-2
PAI-1 Inhibitor
Diaplasinin is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1), exhibiting an IC50 of 295 nM. This compound demonstrates significant antithrombotic activity, making it valuable for research into coagulation disorders. Its ability to modulate PAI-1 levels may provide insights into therapeutic strategies for conditions associated with thrombosis and fibrinolysis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 481631-45-2 |
| Applications | PAI-1 Inhibitor |
| Formula | C32H31N5O |
| Molecular Weight | 501.62 |
| Synonyms | PAI-749 |
| SMILES | CCCCCC1=C(N(C2=C1C=CC=C2)CC3=CC=CC=C3)C4=CC=C5C=C(C=CC5=C4)OCC6=NN=NN6 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.