ZK824859

Catalog No.: A18680

uPA inhibitor

ZK824859

ZK824859 Chemical Structure

CAS NO. 2271122-53-1

ZK824859 is an oral available and selective urokinase plasminogen activator (uPA) inhibitor with IC50s of 79?nM, 1580?nM and 1330?nM for human uPA, tPA, and plasmin, respectively.

Availability: In stock

Package Price Qty
1 mg
$150.00
5 mg
$400.00
10 mg
$700.00
50 mg
$1,900.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ZK824859 is an oral available and selective urokinase plasminogen activator (uPA) inhibitor with IC50s of 79?nM, 1580?nM and 1330?nM for human uPA, tPA, and plasmin, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.71 mL 233.41 mL
0.5 mM 4.67 mL 23.34 mL 46.68 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18680
Actions Inhibitor
CAS No. 2271122-53-1
Formula C23H22F2N2O4
M. Wt 428.43
Solubility DMSO
Purity >98%
Synonyms ZK 824859, ZK-824859
SMILES CC1=CC(OC2=C(F)C=C(F)C(O[[email protected]](CC)C(O)=O)=N2)=CC(C3=CC=CC(CN)=C3)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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