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Biological Activity
ZK824859 is an oral available and selective urokinase plasminogen activator (uPA) inhibitor with IC50s of 79?nM, 1580?nM and 1330?nM for human uPA, tPA, and plasmin, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.34 mL | 116.71 mL | 233.41 mL |
| 0.5 mM | 4.67 mL | 23.34 mL | 46.68 mL |
| 1 mM | 2.33 mL | 11.67 mL | 23.34 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.67 mL |
*The above data is based on the productmolecular weight 428.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18680 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2271122-53-1 |
| Formula | C23H22F2N2O4 |
| M. Wt | 428.43 |
| Purity | >98% |
| Synonyms | ZK 824859, ZK-824859 |
| SMILES | CC1=CC(OC2=C(F)C=C(F)C(O[[email protected]](CC)C(O)=O)=N2)=CC(C3=CC=CC(CN)=C3)=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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United StatesAdooq Bioscience
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