Catalog No.
Product Name
Application
Product Information
Citations
-
Purine Nucleoside Analog
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an alkyne moiety that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it a versatile tool for chemical biology applications. -
Purine Nucleoside Analog
5’-O-TBDPS-5-methyl-2,2’-anhydrouridine is a purine nucleoside analog that exhibits significant antitumor activity. It primarily targets indolent lymphoid malignancies through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound is a valuable tool in cancer research, aiding in the development of therapeutic strategies for treating specific malignancies. -
Oxidation Product of DHICA
5,6-Indolequinone-2-carboxylic acid is an oxidation product of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and serves as a potential biomarker in melanogenesis research. It exhibits important biological activity related to oxidative stress and may influence melanin synthesis pathways. This compound can be utilized in studies exploring skin pigmentation mechanisms and the effects of oxidative agents on cellular processes. -
Purine Nucleoside Analog
2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine is a purine nucleoside analog that plays a pivotal role in cancer research. This compound exhibits significant antitumor activity, particularly in targeting indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for elucidating therapeutic pathways in cancer biology. -
Nucleoside Metabolite
N-Acetyl-L-glutamate 5-phosphate is a nucleoside metabolite produced via the phosphorylation of N-acetyl-L-glutamate by the enzyme N-acetyl-L-glutamate kinase (NAGK). This compound plays a crucial role in amino acid metabolism and is involved in the regulation of nitrogen metabolism. It serves as a valuable tool for researchers studying metabolic pathways and enzyme functions in cellular processes. -
Thymidine Analog
5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine is a thymidine analog that displays insertional activity towards replicated DNA, making it valuable for cell labeling and the tracking of DNA synthesis. This compound features an azide functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups, facilitating its use in bioorthogonal labeling applications. -
Adenosine Analog
5’-O-(4,4’-Dimethoxytrityl)-2’-beta-C-methyl adenosine is an adenosine analog that primarily acts as a smooth muscle vasodilator. This compound exhibits significant biological activities, including the inhibition of cancer progression. It serves as a valuable tool in research applications related to cardiovascular research, cancer therapies, and the study of adenosine receptor signaling pathways. -
Purine Nucleoside Analog
2-Chloro-N6-isopropyladenosine is a purine nucleoside analog that functions by interfering with nucleic acid synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting apoptosis and inhibiting DNA synthesis. It is a valuable reagent for research applications aimed at understanding cancer biology and developing novel therapeutic strategies. -
Purine Nucleoside Analog
3’-O-Methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research applications. This reagent is useful for studies focused on the therapeutic potential of purine analogs in oncology. -
Guanosine Analog
8-(Methylthio)guanosine is a guanosine analog that acts primarily as an immunostimulatory agent. This compound has demonstrated the ability to induce type I interferons in various animal models, resulting in notable antiviral effects. The biological activity of 8-(Methylthio)guanosine is closely linked to the activation of Toll-like receptor 7 (TLR7), making it a valuable tool in research related to antiviral therapies and immune response modulation. -
Nucleoside Metabolite
2-Formaminobenzoylacetate is a nucleoside metabolite that serves as an important intermediate in biochemical pathways. This compound exhibits specific biological activity relevant to the study of nucleoside metabolism and its impact on cellular processes. It is commonly utilized in research focused on nucleotide synthesis and the regulation of nucleic acid function. -
Purine Nucleoside Analog
4′,5′-Didehydro-2′,5′-dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which leads to the induction of apoptosis in cancer cells. This compound is an important tool for researchers studying cancer biology and therapeutic strategies in lymphoid malignancies. -
Purine Nucleoside Analog
2-Chloro-N6-cyclopentyl 2’-deoxy-adenosine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research and therapeutic development, providing insights into the mechanisms of action behind nucleoside analogs. -
Purine Nucleoside Analog
8-Allylthioguanosine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic development. This compound is utilized in studies aimed at understanding the cellular processes involved in cancer progression and treatment response. -
Thymidine Analog
5-(2-Hydroxyethyl)uridine is a thymidine analogue that exhibits insertional activity within replicated DNA. This compound is useful for labeling cells and tracking DNA synthesis, making it a valuable tool in molecular biology and genomic studies. Its ability to mimic thymidine allows for the investigation of cellular processes related to DNA replication and repair. -
Purine Nucleoside Analog
2',3',5'-Tri-O-benzoyl-2-thiouridine is a purine nucleoside analog that acts primarily by inhibiting DNA synthesis and promoting apoptosis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, making it a valuable tool in cancer research. Its unique mechanisms of action allow for the exploration of novel therapeutic approaches in oncology. -
Purine Nucleoside Analog
5-Hydroxy-arabinouridine is a purine nucleoside analog that demonstrates significant antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is essential for studies focused on exploring therapeutic strategies and understanding the molecular pathways involved in lymphoid tumors. -
Active Compound
Cyclopentyluracil is a carbocyclic analogue of uridine that functions as an active compound in nucleoside metabolism. This reagent demonstrates inhibitory activity against nucleoside transporters, making it a valuable tool for studying nucleotide synthesis and cell signaling pathways. Its unique structure allows for the exploration of uridine-related processes in various biological contexts, including antiviral and anticancer research applications. -
Cytidine Analog
5-Phenylcytidine is a cytidine nucleoside analog that functions primarily as an inhibitor of DNA methyltransferases. This class of compounds demonstrates significant anti-metabolic and anti-tumor activities, making them valuable tools in cancer research and epigenetic studies. Researchers can utilize 5-Phenylcytidine to explore its effects on gene regulation and potential therapeutic applications in oncology. -
Purine Nucleoside Analog
2′-Azido-2′-deoxy-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. In addition, this compound serves as a valuable click chemistry reagent due to its azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. -
Purine Nucleoside Analog
9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and induction of apoptosis, making it valuable in cancer research. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing and DBCO or BCN-containing molecules, respectively. -
Nucleoside Metabolite
(7S,8S)-DiHODE is a nucleoside metabolite that plays a significant role in nucleic acid biology. This compound is known for its involvement in cellular signaling pathways and lipid metabolism. It is commonly utilized in research applications focusing on oxidative stress and inflammation, as well as investigations into metabolic disorders and cardiovascular diseases. -
Cytidine Analog
5-Ethyl cytidine is a cytidine analog that primarily targets DNA methyltransferases, inhibiting their activity. It exhibits potential anti-metabolic and anti-tumor properties, making it a valuable compound for cancer research and epigenetic studies. This reagent can aid in understanding the roles of DNA methylation in various cellular processes and disease states. -
Nucleotide Analog
3′-Acetate-UTP is a nucleotide analog that features an acetate modification on the uridine triphosphate (UTP) structure. This compound is primarily utilized in RNA synthesis studies and can serve as a useful tool for probing nucleotide interactions and biochemical pathways. Its unique modification allows for enhanced stability and incorporation into RNA molecules, making it valuable for various applications in molecular biology and biochemistry research. -
Nucleoside Antimetabolite/Analog
Guanoctine hydrochloride is a nucleoside antimetabolite analog that primarily targets nucleic acid synthesis. This compound has demonstrated significant biological activity with antihypertensive properties, making it valuable for cardiovascular research. Its ability to interfere with nucleoside metabolism may provide insights into therapeutic strategies for hypertension and related conditions. -
Uridine Analog
4’-alpha-C-Allyl-2’,3’-bis(O-t-butyldimethylsilyl) uridine is a uridine analog that targets nucleotide metabolic pathways. This compound demonstrates potential antiepileptic effects and can be utilized in research focusing on anticonvulsant and anxiolytic activities. Additionally, it serves as a valuable tool in the development of novel antihypertensive agents. -
Purine Nucleoside Analog
4'-Thioadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is utilized in various studies aimed at understanding tumor biology and developing targeted therapies. -
Purine Nucleoside Analog
2'-Deoxyisocytidine is a purine nucleoside analog specifically designed to inhibit DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. This compound is valuable for research applications focusing on cancer therapeutics and mechanisms of tumor cell death. -
Uridine Analog
2',3',5'-Tri-O-(t-butyldimethylsilyl)-4'-C-hydroxymethyl uridine serves as a uridine analog with notable potential for research in anticonvulsant and anxiolytic activities. By mimicking uridine, this compound facilitates studies aimed at understanding its potential antiepileptic effects and can aid in the development of novel antihypertensive agents. This compound is a valuable tool for exploring uridine-related biological pathways and therapeutic applications. -
Uridine Analog
2’,3’-Bis(O-t-butyldimethylsilyl)-4’,5’-didehydro-5’-deoxyuridine is a uridine analog that acts as a potent tool for investigating the pharmacological effects of uridine-related compounds. This reagent is utilized in studies focusing on anticonvulsant and anxiolytic activities, as well as exploring potential antihypertensive agents. Its structural modifications enhance stability and bioactivity, making it suitable for various chemical and biological research applications. -
Purine Nucleoside Analog
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine is a purine nucleoside analog that targets key pathways in cellular metabolism. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, primarily through the inhibition of DNA synthesis and induction of apoptosis. It serves as a valuable tool for research applications investigating cancer biology and therapeutic strategies. -
Thymidine Analog
2’,3’,5’-Tri-O-acetyl-5-(trifluoromethyl)uridine is a thymidine analog that incorporates into replicating DNA. It exhibits insertional activity, making it suitable for applications in cell labeling and tracking DNA synthesis. This compound is valuable for research in nucleic acid studies and cellular processes involving DNA replication. -
Purine Nucleoside Analog
2’-Deoxy-N6-(3-methoxybenzyl)adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and the development of therapeutic strategies targeting nucleoside metabolism. -
DNA Methylation Inhibitor
Dihydro-5-azacytidine acetate is a nucleoside analog that functions as a DNA methylation inhibitor. It is incorporated into DNA, leading to the disruption of normal methylation patterns. This compound exhibits notable antitumor activity and is utilized in research focused on cancer biology and epigenetic regulation. -
Purine Nucleoside Analog
N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine 3’-CED phosphoramidite is a purine nucleoside analog that serves as a key reagent for the synthesis of modified nucleotides. This compound exhibits significant biological activity, particularly in anticancer applications, by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Its use is particularly relevant in research focused on exploring therapies for indolent lymphoid malignancies. -
Purine Nucleoside Analog
2'-β-C-Methyl-3-deazauridine is a purine nucleoside analog that exhibits significant anticancer properties through the inhibition of DNA synthesis and the induction of apoptosis. This compound is primarily investigated for its potential therapeutic efficacy against indolent lymphoid malignancies. Its ability to interfere with nucleotide metabolism makes it an important research tool in cancer biology and drug development. -
Purine Nucleoside Analog
2,6-Dichloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological efficacy is attributed to mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications in cancer biology and therapeutic development. -
Purine Nucleoside Analog
N,N-Dimethyl-2'-O-methylcytidine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, facilitating the study of nucleoside metabolism and potential therapeutic strategies. -
Purine Nucleoside Analog
N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool for research applications focused on cancer therapeutics and the study of nucleoside metabolism. -
Purine Nucleoside Analog
(2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies exploring therapeutic strategies and the biochemical pathways associated with nucleoside metabolism. -
Purine Nucleoside Analog
9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog that primarily targets DNA synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, contributing to its efficacy in cancer research. The anticancer mechanisms include the inhibition of DNA replication and the induction of apoptosis, making it a valuable reagent for studying therapeutic strategies in oncology. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine acts as a purine nucleoside analog with significant anticancer properties. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic development. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’-O-methyl-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. Its unique structural modifications enhance its potential in studying purine metabolism and the mechanisms of action in cancer treatments. -
Purine Nucleoside Analog
3′-Bromo-3′-deoxythymidine is a purine nucleoside analog that exhibits significant antitumor activity primarily through the inhibition of DNA synthesis. This compound is effective against indolent lymphoid malignancies, contributing to apoptosis induction and disrupting cellular proliferation. It serves as a valuable tool in cancer research, particularly for exploring therapeutic strategies targeting nucleoside metabolism and DNA replication processes. -
Nucleoside Analogue
8-Azakinetin riboside is a nucleoside analogue that exhibits cytotoxic activity. It is structurally related to kinetin riboside, making it a valuable compound for research investigating the effects of nucleoside analogues on cellular pathways. This reagent is applicable in studies focused on cancer biology and the modulation of cellular growth and death. -
Cytidine Analog
2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog that functions as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor properties, making it a valuable tool for cancer research and studies involving epigenetic modulation. Its unique structure allows for exploration of the regulatory mechanisms of methylation in cellular processes. -
Adenosine Analog
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog that primarily targets adenosine receptors. It exhibits significant smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. This compound is valuable for research applications focusing on vascular biology, oncology, and the investigation of adenosine signaling pathways. -
Nucleoside Metabolite
Dixanthosine tetraphosphate is a nucleoside metabolite that plays a critical role in cellular signaling pathways. This compound is primarily involved in the regulation of nucleotide metabolism and can influence various cellular processes, making it valuable for research in cell biology and biochemistry. Its distinct structure also facilitates studies on phosphoribosyltransferase activity and nucleoside triphosphate synthesis. -
Cytidine Analog
2’-Deoxy-2’-fluoro-5-methylcytidine is a cytidine nucleoside analog that functions as an inhibitor of DNA methyltransferases. Its mechanism of action involves modulating DNA methylation, which can lead to alterations in gene expression. This compound demonstrates potential anti-metabolic and anti-tumor activities, making it a valuable tool for cancer research and epigenetic studies. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog exhibiting broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and induction of apoptosis, making it valuable in cancer research. Additionally, this compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating advanced conjugation studies in chemical biology.
