Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
N1-Propargylpseudouridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and induction of apoptosis, contributing to its efficacy in cancer research. Additionally, N1-Propargylpseudouridine functions as a click chemistry reagent, possessing an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various biochemical applications. -
Adenosine Analog
8-Allylthioadenosine is an adenosine analog that primarily targets adenosine receptors. It demonstrates smooth muscle vasodilatory effects and has been implicated in inhibiting cancer progression, making it a valuable compound for oncology research. Its utility extends to studies involving vascular biology and the modulation of cellular signaling pathways. -
Purine Nucleoside Analog
5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool in cancer research, aiding in the exploration of therapeutic strategies targeting nucleic acid metabolism and cellular proliferation. -
Adenosine Analog
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analog with significant biological activity. This compound primarily acts as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. Research applications include exploring mechanisms of vasodilation and investigating therapeutic strategies in oncology. -
Purine Nucleoside Analog
Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is a purine nucleoside analog that functions primarily by interfering with DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the induction of apoptosis. It serves as a valuable tool for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
N4-Desmethyl wyosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding and developing therapies for various types of hematological cancers. -
Purine Nucleoside Analog
2',3'-Bis(O-(t-butyldimethylsilyl)-5-methoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. Its unique structure enhances cellular uptake and stability, facilitating studies in nucleoside metabolism and targeted cancer therapies. -
Purine Nucleoside Analog
2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, which are crucial mechanisms in cancer treatment. Its efficacy in targeting specific cancer pathways makes it a valuable reagent for researchers studying tumor biology and potential therapeutic interventions. -
Pyrimidine Nucleoside Analog
4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog that targets nucleic acid synthesis. This compound exhibits significant biological activities including the inhibition of DNA and RNA synthesis, as well as antiviral and immunomodulatory effects. It is valuable in biochemical research and may be applied in the development of therapeutic strategies for various diseases, including cancer and viral infections. -
Purine Nucleoside Analog
5-Nitro-1-(3-azido-3-deoxy-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This versatility makes it a valuable tool in chemical biology and medicinal chemistry research. -
Purine Nucleoside Analog
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine is a purine nucleoside analog that acts as a potent inhibitor of DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleic acid metabolism. It is especially useful in cancer research for exploring therapeutic strategies and understanding the molecular mechanisms underlying tumor growth. -
Purine Nucleoside Analog
2’,3’,5’-Tri-O-benzoyl-4-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms are primarily due to the inhibition of DNA synthesis and the induction of apoptosis. This reagent is valuable for research applications aimed at understanding the biochemical pathways of cancer and developing potential therapeutic strategies. -
Purine Nucleoside Analog
3'-Deoxy-N6-isopentenyl adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications aimed at understanding and developing novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
3'-O-Acetylthymidine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in cancer research. Its properties are useful for studying the mechanisms of tumor cell proliferation and survival, contributing to the development of targeted cancer therapies. -
Purine Nucleoside Analog
7-(Butyn-2-yl)-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent due to its alkyne functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This dual functionality makes it a valuable tool for both therapeutic and research applications. -
Purine Nucleoside Analog
2'-O-Phthalimidopropyl uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications aimed at understanding and developing therapies for various malignancies. -
Purine Nucleoside Analog
N4-Benzoyl-5’-O-(4,4-dimethoxytrityl)-3’-deoxy cytidine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is useful for studies focused on nucleoside analogs and their potential therapeutic applications in oncology. -
Purine Nucleoside Analog
5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies focused on understanding and developing therapeutic strategies for treating various hematological cancers. -
Purine Nucleoside Analog
2'-O-Hexadecanyl-2-aminoadenosine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This compound can be utilized to study the effects of purine metabolism and nucleoside transport in various cellular contexts. -
Purine Nucleoside Analog
5′-Deoxy-5′-iodo-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focusing on cancer biology and therapeutic development. -
Purine Nucleoside Analog
5-Fluoro-4’-thiouridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This reagent is suitable for studies focused on nucleoside analogs and their potential applications in oncology. -
Purine Nucleoside Analog
2’-β-C-Ethynylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, 2’-β-C-Ethynylcytidine serves as a click chemistry reagent, featuring an alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating bioconjugation applications in chemical biology research. -
Purine Nucleoside Analog
8-Chloroinosine is a purine nucleoside analogue that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is suitable for research applications focused on elucidating the therapeutic potential of purine analogs in cancer treatment. -
Purine Nucleoside Analog
4'-Thioinosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This compound is instrumental in studying the effects of nucleoside analogs on cellular processes and can aid in the exploration of new treatment strategies for malignancies. -
Purine Nucleoside Analog
6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one is a purine nucleoside analogue that exhibits significant antitumor activity, particularly in the treatment of indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis in cancer cells, making it a valuable tool for cancer research and therapeutic development. Its diverse biological activities are essential for exploring novel approaches in oncological studies. -
Purine Nucleoside Analog
5-Aminocarbonylmethyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological effects primarily stem from the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development strategies targeting nucleoside metabolism. -
Cytidine Analog
N4,N4-Dimethylarabinocytidine is a cytidine nucleoside analog that primarily targets DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it a valuable tool for cancer research. Its ability to inhibit DNA methylation contributes to its utility in studies focused on epigenetics and gene regulation. -
Purine Nucleoside Analog
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite is a purine nucleoside analog designed for use in molecular biology applications. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, primarily through mechanisms such as DNA synthesis inhibition and apoptosis induction. It serves as an essential reagent for researchers investigating the therapeutic potential of nucleoside analogs in cancer treatment. -
Purine Nucleoside Analog
3’-Deoxy-3’-azido-isocytidine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, containing an azide group that is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. These properties make it valuable for various research applications in chemical biology and medicinal chemistry. -
Purine Nucleoside Analog
2-Thiopseudouridine is a purine nucleoside analog with significant potential in cancer research. It exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. The compound's anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for studying cancer biology and developing therapeutic strategies. -
Purine Nucleoside Analog
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-fluorouridine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is essential for studies aimed at developing therapies for hematological malignancies and understanding the biochemical pathways involved in tumor progression. -
Purine Nucleoside Analog
5-Methyl-2-thio-xylo-uridine is a purine nucleoside analog that exhibits broad antitumor activity primarily against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound aids in the study of therapeutic strategies for various hematological cancers, contributing to the understanding of cellular responses and treatment efficacy. -
Purine Nucleoside Analog
2’-Deoxy-2’-fluoroarabino-O6-methyl inosine is a purine nucleoside analog that exerts its biological activity primarily through the inhibition of DNA synthesis. This compound demonstrates significant antitumor effects, making it particularly relevant in the study of indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis, which further enhances its potential in cancer research applications. -
Purine Nucleoside Analog
N6-Benzoyl-3'-fluoro-2',3'-dideoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at exploring its potential therapeutic applications in oncology. -
Purine Nucleoside Analog
5-Azidomethyl-2’-beta-methyl uridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. In addition, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This makes it an invaluable tool for chemical biology and medicinal chemistry applications. -
Purine Nucleoside Analog
8-Aza-7-deazguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic exploration. This compound is suitable for studies aimed at understanding the molecular pathways involved in tumorigenesis and for developing potential anticancer strategies. -
Purine Nucleoside Analog
N4-Benzoyl-2'-deoxy-5'-O-DMTr-2'-fluoro-5-methylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in the treatment of indolent lymphoid malignancies. Its primary mechanisms of action involve inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool for cancer research, enabling the study of nucleoside metabolism and the development of novel therapeutic strategies. -
Cytidine Analog
5’(R)-C-Methylcytidine is a synthetic cytidine nucleoside analog that inhibits DNA methyltransferases. This compound exhibits significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research. Its ability to interfere with DNA methylation processes provides insights into gene regulation and potential therapeutic interventions. -
Purine Nucleoside Analog
2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog that primarily inhibits DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. Its research applications include studying cancer cell biology and exploring therapeutic strategies for hematological cancers. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine is a purine nucleoside analog that effectively inhibits DNA synthesis and induces apoptosis. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its application in research underscores its potential as a therapeutic agent in cancer treatment strategies. -
Purine Nucleoside Analog
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog that primarily inhibits DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. Its potential applications in cancer research make it a valuable tool for studying mechanisms of tumorigenesis and evaluating therapeutic strategies. -
Purine Nucleoside Analog
2'-Deoxy-5,N4,N4-trimethylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer properties are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, helping to elucidate mechanisms of tumor growth and potential therapeutic strategies. -
Purine Nucleoside Analog
3’-Deoxy-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is instrumental in various research applications aimed at understanding and developing therapies for malignancies resistant to conventional treatments. -
Purine Nucleoside Analog
7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analog known for its anticancer properties. This compound exhibits significant biological activity against indolent lymphoid malignancies, primarily through the inhibition of DNA synthesis and the induction of apoptosis. It represents a valuable tool for research in cancer therapeutics and the study of purine metabolism. -
Purine Nucleoside Analog
MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite is a purine nucleoside analog that serves as a versatile building block in oligonucleotide synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. It is primarily utilized in research focused on the development of novel therapeutics and the study of nucleic acid interactions. -
Purine Nucleoside Analog
2'-Bromo-2'-deoxy-5-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is valuable for research applications focusing on anticancer therapeutics and the study of nucleoside metabolism. -
Purine Nucleoside Analog
2’,3’-Dideoxy-5-fluorocytidine is a purine nucleoside analog that exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is instrumental for studies focusing on the development of targeted therapies and the understanding of nucleoside metabolism in tumor biology. -
Purine Nucleoside Analog
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog that targets DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. Its applications in cancer research make it a valuable tool for studying purine metabolism and therapeutic strategies in oncology. -
Purine Nucleoside Analog
5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily targets the inhibition of DNA synthesis and induces apoptosis, making it valuable in the study of indolent lymphoid malignancies. Its unique structural modifications enhance its effectiveness in various cancer research applications, particularly in understanding the biology of tumor cell proliferation and survival. -
Purine Nucleoside Analog
N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This reagent can be utilized to elucidate the effects of nucleoside modifications on cellular processes and therapeutic responses.
