Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone is a purine nucleoside analog that demonstrates significant antitumor activity by targeting indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding its effects on cellular proliferation and tumorigenesis. -
Adenosine Analog
N6,N6-Dimethyl-xylo-adenosine is an adenosine analog with a primary mechanism of action involving modulation of adenosine receptors. This compound has demonstrated significant smooth muscle vasodilator activity and holds potential in inhibiting cancer progression. It is widely utilized in research applications focusing on vascular biology and oncology. -
Purine Nucleoside Analog
3'-Deoxy-3'-fluoro-5-fluorouridine is a purine nucleoside analog known for its potent antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its application in cancer research aids in elucidating mechanisms of tumor cell proliferation and survival, contributing to the development of novel therapeutic strategies. -
Purine Nucleoside Analog
2-Amino-6-chloropurine-9-(2’-O-propargyl)riboside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent due to the presence of an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules, facilitating various bioconjugation applications in chemical biology. -
Purine Nucleoside Analog
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-5-methoxy uridine is a purine nucleoside analog known for its antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is suitable for studies focused on nucleoside metabolism and anticancer therapeutics. -
Purine Nucleoside Analog
5’-O-DMTr-3’-deoxyuridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. This compound can be utilized to investigate the pathways involved in tumor growth and resistance, providing insights into potential treatment strategies. -
Purine Nucleoside Analog
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and the development of therapeutic strategies targeting nucleic acid metabolism. -
Purine Nucleoside Analog
2′,3′-O-Isopropylideneisocytidine is a purine nucleoside analog that exerts significant antitumor activity by targeting indolent lymphoid malignancies. This compound primarily functions through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. Its unique mechanism highlights its potential in various therapeutic applications aimed at treating specific types of malignancies. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. This compound demonstrates notable antitumor activity, particularly against indolent lymphoid malignancies, and induces apoptosis in cancer cells. Its applications in research provide valuable insights into the mechanisms of cancer treatment and therapeutic resistance. -
Purine Nucleoside Analog
2’-Amino-2’-deoxy-5-methyl uridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound offers potential for exploring therapeutic strategies in oncology and advancing the understanding of nucleoside analog effects in tumor biology. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-5-fluoro-beta-L-cytidine is a purine nucleoside analog known for its potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound features an azide group, making it suitable for click chemistry applications, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules, as well as DBCO or BCN groups. -
Purine Nucleoside Analog
2-Bromoadenosine is a purine nucleoside analog that exhibits potential antimalarial and anticancer activities. It is known to target indolent lymphoid malignancies through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. This compound is relevant for research applications focused on cancer therapy and elucidating the effects of purine analogs in cellular processes. -
Adenosine Analog
5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite is an adenosine analog known for its role as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable in various research applications related to cardiovascular health and oncology. Its structural properties allow for incorporation into oligonucleotides, facilitating studies on adenosine signaling pathways and therapeutic development. -
Purine Nucleoside Analog
2′,3′-Dideoxy-5-fluorouridine is a purine nucleoside analog that exerts its effects by inhibiting DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting apoptosis and disrupting cellular proliferation. It serves as a valuable tool in cancer research, aiding in the understanding of therapeutic mechanisms and the development of novel treatments. -
Nucleoside Antimetabolite/Analog
Thiamiprine is a nucleoside antimetabolite and analog related to azathioprine, primarily targeting DNA synthesis. This compound exhibits cytotoxic effects in vitro, demonstrating activity comparable to its parent compound, though its arabinoside variant is inactive and non-toxic. In vivo studies using the rat adjuvant arthritis model indicate that the riboside and 2'-deoxyriboside forms are less active than the parent compound, while maintaining a distinct safety profile. Thiamiprine is valuable for research applications focused on immunosuppression and cellular proliferation. -
Purine Nucleoside Analog
9-(2-β-C-Methyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that exerts its effects by targeting cellular pathways involved in DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. It serves as a valuable tool for research applications in cancer biology and therapeutics development. -
Purine Nucleoside Analog
7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its biological activity includes inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized to study mechanisms of cancer cell proliferation and therapeutic resistance, contributing to the development of targeted cancer therapies. -
Purine Nucleoside Analog
3'-O-Methyl-2'-O-acetyl-5'-O-benzoyluridine is a purine nucleoside analog known for its broad antitumor activity against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, particularly in studying cell proliferation and the apoptotic pathways in lymphoid malignancies. -
Purine Nucleoside Analog
2-Trifluoromethyl adenosine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Cytidine Analog
2',3',5'-Tri-O-benzoyl-5-azacytidine serves as a potent cytidine analog with a primary mechanism of inhibiting DNA methyltransferases. This compound demonstrates significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research and epigenetic studies. Its ability to interfere with DNA methylation processes positions it as an important reagent for investigating gene expression regulation and therapeutic interventions in oncology. -
Cytidine Analog
5-Methoxy cytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research and epigenetics studies. Its unique properties enable investigations into the regulatory roles of DNA methylation in various biological processes and diseases. -
Nucleoside Analogue
1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nucleoside analogue targeting cellular enzymatic pathways. This compound exhibits potential antiviral and anticancer activity, making it a valuable tool for researchers studying nucleoside metabolism and related therapeutic applications. Its unique structural modifications enhance its stability and efficacy in various biological systems, facilitating investigations into nucleoside function and biochemistry. -
Purine Nucleoside Analog
3',4-Dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic interventions targeting nucleoside metabolism. -
Purine Nucleoside Analog
1-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that targets critical pathways in cancer cells. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as DNA synthesis inhibition and the induction of apoptosis. Its unique structural features make it a valuable tool in cancer research, particularly for investigating therapeutic strategies in lymphoid cancers. -
Purine Nucleoside Analog
2′-O-Methyl-2-amino-6-chloropurine riboside is a purine nucleoside analog that serves as an important tool in cancer research. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by interfering with DNA synthesis and inducing apoptosis in cancer cells. Its versatile applications in cellular and molecular biology make it a valuable reagent for studying therapeutic strategies against various malignancies. -
Adenosine Analog
3'-β-C-Methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits biological activity as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. It is useful in research applications focused on cardiovascular function and cancer biology. -
Purine Nucleoside Analog
4’-C-Methyl-4-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptotic pathways in cancer cells. Its research applications include exploring mechanisms of cancer treatment and evaluating therapeutic efficacy in oncology studies. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog that primarily targets nucleotide metabolism. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, facilitating the exploration of therapeutic strategies targeting purine metabolism. -
Purine Nucleoside Analog
5-Hydroxy-2'-O-methyluridine is a purine nucleoside analog that exhibits significant anticancer activity. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis in cancer cells, making it a valuable tool in research aimed at understanding treatments for indolent lymphoid malignancies. Its biological properties position it as a promising candidate for further investigation in cancer therapy development. -
Purine Nucleoside Analog
6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one is a purine nucleoside analog with promising antitumor activity against indolent lymphoid malignancies. Its cytotoxic effects primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound's unique structure allows for further exploration in the development of targeted therapies for various malignancies. -
Purine Nucleoside Analog
3’-N-Acetyl-3’-amino-3’-deoxyuridine is a purine nucleoside analog primarily involved in inhibiting DNA synthesis. This compound exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inducing apoptosis and impairing cellular proliferation, making it a valuable reagent for cancer research and therapeutic studies. -
Purine Nucleoside Analog
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studying mechanisms of cancer cell proliferation and developing therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
3’,5’-Di-O-acetyl-2’-deoxy-N3-methyl uridine is a purine nucleoside analog that acts primarily by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include induction of apoptosis and disruption of cellular proliferation, making it a valuable reagent for research in oncology and molecular biology. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-N6-methyladenosine is a purine nucleoside analogue designed for research applications in cancer biology. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. Additionally, it serves as a versatile click chemistry reagent, featuring an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules or DBCO/BCN-functionalized compounds, facilitating bioconjugation studies. -
Purine Nucleoside Analog
2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for researchers investigating therapeutic strategies and mechanisms of action in cancer biology. -
Purine Nucleoside Analog
N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The compound functions primarily by inhibiting DNA synthesis, leading to the induction of apoptosis in cancer cells. Its applications in research include exploring mechanisms of cancer cell proliferation and evaluating therapeutic strategies targeting nucleosynthesis pathways. -
Purine Nucleoside Analog
2’-Chloro-N6-(4-trifluoromethyl)benzyl adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is suitable for studies focused on understanding tumor biology and developing therapeutic strategies targeting nucleoside pathways. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-5-trifluoromethyluridine is a purine nucleoside analogue primarily known for its broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds. -
Purine Nucleoside Analog
5’-O-TBDPS-2,2’-anhydrouridine is a purine nucleoside analog that acts primarily by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism also includes the induction of apoptosis, making it a valuable tool for research focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
3-epi-Azido-3-deoxythymidine is a purine nucleoside analog known for its antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This reagent is suitable for studies exploring therapeutic strategies in oncology and the mechanistic understanding of tumor cell behavior. -
Purine Nucleoside Analog
2,3’-Anhydrothymidine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which leads to subsequent induction of apoptosis. This compound serves as a valuable tool in cancer research, contributing insights into therapeutic strategies for lymphoid cancers. -
Purine Nucleoside Analog
N2-iso-Butyryl-8-azaguanosine is a purine nucleoside analog that demonstrates significant biological activity against indolent lymphoid malignancies. Its anticancer properties are attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for research applications in oncology and cancer treatment studies. -
Purine Nucleoside Analog
1-(2,3-Dideoxy-β-D-erythro-hexopyranosyl)cytosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for investigations into therapeutic strategies targeting nucleoside metabolism and malignancy treatment. -
Purine Nucleoside Analog
2′-Deoxy-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is utilized for exploring therapeutic strategies and understanding the underlying biology of tumor progression. -
Purine Nucleoside Analog
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. This compound operates by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in cancer research and therapeutic studies. Its unique structural modifications enhance its efficacy as a research reagent in exploring mechanisms of cancer treatment. -
Adenosine Analog
9-(2-Deoxy-β-D-threo-pentofuranosyl)-9H-purin-6-amine is an adenosine analog that primarily acts on adenosine receptors. This compound exhibits smooth muscle vasodilatory activity and has demonstrated potential in inhibiting the progression of various cancers. It serves as a valuable tool in biochemical research focusing on vascular biology and oncology. -
Purine Nucleoside Analog
2'-Deoxy-N2-isopropyl guanosine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits notable antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as apoptosis induction and DNA synthesis inhibition. This compound serves as a valuable tool for researchers investigating cancer biology and therapeutic strategies in oncology. -
Purine Nucleoside Analog
2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a purine nucleoside analog that exerts its biological activity by inhibiting DNA synthesis and inducing apoptosis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its role as a nucleoside analog makes it a valuable tool for research in cancer biology and therapeutic development. -
Adenosine Analog
2-Amino-2′-O-(2-methoxy-2-oxoethyl)adenosine is an adenosine analogue targeting adenosine receptors. It exhibits smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. This compound is valuable for research applications focusing on vascular biology and cancer therapeutics. -
Purine Nucleoside Analog
N6-(4-Methoxybenzyl)-2’-C-methyl adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is particularly useful for studying the effects of purine analogs on tumor progression and therapeutic responses.
