Catalog No.
Product Name
Application
Product Information
Citations
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Nucleoside Analog
5'-OH-(2'OMe-G)pG is a nucleoside analog that serves as a monomeric building block for nucleic acid synthesis. Its modified structure enhances stability and increases resistance to nucleases. This reagent is particularly useful in the development of oligonucleotides for research applications in gene therapy, antisense oligonucleotides, and RNA interference studies. -
Nucleoside Analog
DMTr-2'-ara-F-dG(dmf)-3'-CE-phosphoramidite is a modified nucleoside analog designed for use in nucleic acid synthesis. This reagent serves as a key building block for generating oligonucleotides with specific functionalities. Its incorporation facilitates the study of nucleic acid structure and function, making it valuable in applications such as gene expression analysis, antisense oligonucleotide development, and nucleic acid-based therapeutics. -
Nucleoside Analog
2'-Deoxy-3',5'-CDP (pdCp) is a nucleoside analog utilized in nucleic acid synthesis. As a key monomer, it plays a vital role in the construction of DNA strands during various molecular biology applications. Its incorporation into oligonucleotides can enhance studies in genetic engineering, gene expression analysis, and therapeutic development. -
Nucleoside Analog
2'-OMe-uTP is a nucleoside analog that serves as a crucial monomer for nucleic acid synthesis. Its modification enhances the stability and bioavailability of RNA molecules, making it valuable for research applications in RNA biology, therapeutic development, and the study of gene expression. This compound is instrumental in the synthesis of modified RNA, allowing for innovative approaches in the design of RNA-based therapeutics and molecular probes. -
Nucleoside Analog
3'-O-Phthalimido-2'-deoxythymidine is a nucleoside analog that serves as a monomeric precursor for nucleic acid synthesis. This compound is primarily utilized in research applications related to DNA and RNA assembly, enabling the exploration of oligonucleotide properties and functions. Its incorporation into synthetic pathways enhances the study of genetic mechanisms and therapeutic development. -
Nucleoside Antimetabolite/Analog
1-Acetyl-3-o-toluyl-5-fluorouracil is a nucleoside antimetabolite that serves as a 5-fluorouracil analog. This compound exhibits significant antitumor activity, making it a valuable tool in cancer research. It is primarily utilized to study cellular mechanisms of chemoresistance and to evaluate therapeutic strategies for various malignancies. -
Purine Nucleoside Analog
3-O-(4-Methoxybenzyl)-4-C-hydroxymethyl-1,2-O-isopropylidine-alpha-D-ribofuranose is a purine nucleoside analog that exhibits significant anticancer activity. It primarily targets indolent lymphoid malignancies through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research focusing on cancer therapeutics and the underlying molecular pathways involved in tumor progression. -
Purine Nucleoside Analog
2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily due to the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, incorporating an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, including those with DBCO or BCN moieties. -
Nucleoside Metabolite
(S)-5-Amino-3-oxohexanoic acid acts as a nucleoside metabolite with significant implications in biochemical research. This compound plays a role in metabolic pathways involving amino acid synthesis and nucleoside metabolism. It is utilized in studies of enzyme activity and may contribute to the understanding of metabolic disorders and nucleoside-related functions in cellular processes. -
Purine Nucleoside Analog
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analog. This compound exhibits significant antitumor activity against indolent lymphoid malignancies by targeting DNA synthesis and inducing apoptotic pathways. Its unique mechanism of action makes it a valuable tool for cancer research and a promising candidate for therapeutic development. -
Purine Nucleoside Analog
Thymine 1-β-D-arabinofuranoside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on the development and exploration of novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog that acts by targeting critical pathways involved in cancer biology. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis in cancerous cells. It is a valuable reagent for researchers investigating therapeutic strategies in oncology and nucleic acid-based applications. -
Purine Nucleoside Analog
5-O-Benzoyl-1,2,3-tri-O-acetyl-4-C-methyl-D-ribofuranose is a purine nucleoside analog that demonstrates significant antitumor activity. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool for research in cancer biology. It is particularly relevant for investigating treatments for indolent lymphoid malignancies and other related malignancies. -
Purine Nucleoside Analog
N1-(1,1,1-Trifluoroethyl)pseudouridine is a purine nucleoside analog that exerts its antitumor effects by inhibiting DNA synthesis and promoting apoptosis. This compound is primarily utilized in the research of indolent lymphoid malignancies, where it demonstrates significant potential for therapeutic applications. Its unique structure and biological activity make it a valuable tool for studying cancer cell proliferation and survival mechanisms. -
Nucleoside Metabolite
11,14,15-THETA (11,14,15-Trihydroxyeicosatrienoic acid) is a nucleoside metabolite known for its role in various biological processes. This compound exhibits significant bioactivity, influencing lipid signaling pathways and inflammatory responses. It is commonly utilized in research exploring metabolic pathways, inflammation, and cell signaling mechanisms. -
Adenosine Analog
8-Methylthio-adenosine is an adenosine analog that primarily acts as a smooth muscle vasodilator. It has demonstrated the potential to inhibit cancer progression, making it a valuable tool in cancer research and therapeutic investigations. This compound is relevant for studies exploring the biochemical pathways influenced by adenosine and its analogs. -
Guanosine Analog
1,2'-O-Dimethylguanosine is a guanosine analogue that primarily targets Toll-like receptor 7 (TLR7). It exhibits immunostimulatory activities and has been shown to induce type I interferons in certain animal models, leading to antiviral effects. This compound serves as a valuable tool in research focused on innate immunity and therapeutic applications in viral infections. -
Purine Nucleoside Analog
5’(R)-C-Methyl-3-deazauridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research. This compound is suitable for studies focused on the mechanisms of action of nucleoside analogs and their therapeutic potential in oncology. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-5-iodouridine is a purine nucleoside analog that targets DNA synthesis pathways to exhibit antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily mediated through inhibition of DNA replication and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne, DBCO, or BCN-functionalized molecules. This makes it a valuable tool for bioconjugation applications in chemical biology research. -
Adenosine Analog
3,5-Bis-O-(2,4-dichlorobenzyl)adenosine is an adenosine analog that primarily serves as a vasodilator through its action on smooth muscle. This compound has also demonstrated potential in inhibiting cancer progression, making it relevant for various therapeutic research applications. Its structural modifications allow for enhanced biological activity, contributing to studies in drug design and development focused on cardiovascular and oncology therapies. -
Purine Nucleoside Analog
3’-Deoxy-3’-α-C-methyl-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in malignant cells. This compound is valuable for research applications centered on cancer biology and the development of novel therapeutic strategies against lymphoid cancers. -
Guanosine Analog
3'-O-MOE-G(iBu)-2'-phosphoramidite is a guanosine analog that targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity, which can lead to the induction of type I interferons in various animal models, thereby generating antiviral effects. Its unique properties make it valuable for research applications focused on immune response and antiviral therapies. -
Purine Nucleoside Analog
3'-Amino-3'-deoxy-5-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for researchers studying cancer biology and the therapeutic potential of nucleoside analogs in oncology. -
Thymidine Analog
1-(β-D-Xylofuranosyl)-5-methyluracil is a thymidine analog that functions by incorporating into replicated DNA. This compound exhibits insertional activity, making it useful for labeling cells and investigating DNA synthesis dynamics. It serves as a valuable tool in studies of cell proliferation and nucleic acid metabolism. -
Pyrimidine Nucleoside Analog
4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a pyrimidine nucleoside analog that targets nucleic acid metabolism. This compound demonstrates significant biological activity, including the inhibition of DNA and RNA synthesis, as well as antiviral and immunomodulatory effects. Its versatile properties make it a valuable tool for research applications in cancer biology, virology, and immune response studies. -
Nucleoside Metabolite
(24E)-3α,7α-Dihydroxy-5β-cholest-24-enoyl-CoA is a nucleoside metabolite that plays a critical role in cholesterol metabolism. It serves as a substrate for various enzymatic reactions involved in lipid biosynthesis and has potential applications in studying cellular pathways related to lipid synthesis and degradation. This compound is valuable for researchers investigating metabolic disorders and cholesterol-related diseases. -
Purine Nucleoside Analog
2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is a purine nucleoside analog that targets mechanisms involved in DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its pharmacological effects are linked to the induction of apoptosis and inhibition of cellular proliferation, making it a valuable tool for cancer research and therapeutic development. -
Purine Nucleoside Analog
2-Aminomethyl adenosine is a purine nucleoside analog known for its antitumor activity against indolent lymphoid malignancies. This compound exerts its effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. Its applications in cancer research make it a valuable tool for studying the mechanisms of tumor cell proliferation and survival. -
Pyrimidine Nucleoside Analog
4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog targeting nucleic acid metabolism. This compound demonstrates significant biological activities, including inhibition of DNA and RNA synthesis, antiviral properties, and immunomodulatory effects. It is a valuable research tool for studying molecular mechanisms in cancer biology, virology, and immunology. -
Nucleoside Metabolite
3-Oxo-3-ureidoisobutyrate is a nucleoside metabolite involved in various biochemical pathways. It plays a crucial role in the metabolism of nucleotides, influencing nucleobase synthesis and cellular energy homeostasis. This compound is useful in research applications related to nucleotide metabolism and can aid in understanding the regulatory mechanisms of nucleoside derivatives in cellular processes. -
Purine Nucleoside Analog
5'-Deoxy-5'-N,N-diethylamino thymidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research and therapeutic studies focused on lymphoid neoplasms. This compound is instrumental in understanding the role of nucleoside analogs in cancer treatment and their potential effects on cell proliferation and viability. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-5-methyluridine is a purine nucleoside analog primarily effective in inhibiting DNA synthesis, which promotes apoptosis in cancer cells. Its broad antitumor activity is particularly relevant for indolent lymphoid malignancies. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, facilitating various biochemical applications in research. -
Purine Nucleoside Analog
2’-dG (iBu)-2’-phosphoramidite is a purine nucleoside analog that selectively targets DNA synthesis pathways. It exhibits significant antitumor activity against indolent lymphoid malignancies through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. This reagent is essential for research applications focused on cancer biology and nucleic acid synthesis. -
Purine Nucleoside Analog
8-Methyl-2’-deoxyguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic studies. This compound is instrumental in investigating mechanisms of action and developing targeted treatments for various malignancies. -
Thymidine Analog
5-Hydroxymethyl-arauridine is a thymidine analogue that exhibits insertional activity towards replicated DNA. This compound is particularly valuable for labeling cells and monitoring DNA synthesis in various research applications. Its ability to mimic natural nucleotides makes it an effective tool for investigating cellular proliferation and the dynamics of DNA replication. -
Purine Nucleoside Analog
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable research tool for investigating therapeutic strategies in cancer treatment and understanding the molecular pathways involved in tumor progression. -
Guanosine Analog
7-Cyano-7-deaza-2'-deoxy guanosine is a guanosine analog with significant immunostimulatory properties. It has been demonstrated to induce type I interferons in various animal models, thereby exerting antiviral effects. The biological activity of this compound is closely linked to the activation of Toll-like receptor 7 (TLR7), making it a valuable tool for research in immunology and antiviral therapies. -
Adenosine Analog
N6-Benzoyl-7'-O-DMT-morpholino adenine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits notable biological activities, including smooth muscle vasodilation and the potential inhibition of cancer progression. It is commonly utilized in research applications related to cardiovascular studies and cancer therapeutics, contributing valuable insights into adenosine signaling and its effects on physiological processes. -
Purine Nucleoside Analog
5-Difluoromethyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This reagent is valuable for research applications focused on cancer biology and the development of therapeutic strategies targeting tumor cell proliferation. -
Purine Nucleoside Analog
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4(1H)-pyrimidinone is a purine nucleoside analog known for its potential anticancer activity. It exhibits efficacy against indolent lymphoid malignancies primarily through mechanisms that inhibit DNA synthesis and induce apoptosis. This compound is valuable for research in cancer biology and drug development focused on targeted therapies for lymphoid-related tumors. -
5'-dAMP Analogue
5'-dAMPS is an analogue of 5'-deoxyadenosine monophosphate (5'-dAMP) that serves as a potential substrate, competitive inhibitor, or regulator of enzymes that interact with dAMP. This compound is valuable in biochemical research for studying nucleotide metabolism and enzyme kinetics, particularly in the context of adenine nucleotide chemistry. Its ability to modulate enzyme activity makes it a useful tool for exploring the roles of dAMP-related pathways in cellular processes. -
Purine Nucleoside Analog
N4-Amino-2'-C-methylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is relevant for studies investigating nucleoside metabolism and the development of therapeutic strategies in oncology. -
Purine Nucleoside Analog
Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Its unique properties make it a valuable tool for researchers investigating therapeutic approaches to cancer treatment. -
Cytidine Analog
Xylocytidine is a cytidine analog that primarily inhibits DNA methyltransferases, which are crucial enzymes involved in DNA epigenetic regulation. This compound exhibits potential anti-metabolic and anti-tumor activities, making it a valuable tool for cancer research and studies focused on gene expression regulation. Its role in modulating DNA methylation offers promising applications in understanding epigenetic alterations in various diseases. -
Purine Nucleoside Analog
N6-Ethyl-2’-C-methyladenosine is a purine nucleoside analog that exerts significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a useful tool for research into cancer biology, drug development, and therapeutic applications in hematological malignancies. -
Purine Nucleoside Analog
N4-Benzoyl-2’-deoxy-2’,2’-difluorocytidine is a purine nucleoside analog known for its potent antitumor activity. This compound primarily targets indolent lymphoid malignancies by interfering with DNA synthesis and promoting apoptosis in cancer cells. It serves as a valuable tool for researchers investigating the mechanisms of cancer treatment and exploring therapeutic strategies in oncology. -
Purine Nucleoside Analog
4-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile is a purine nucleoside analog that exhibits significant biological activity against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer therapeutics and the study of nucleoside analog effects on cellular processes. -
Purine Nucleoside Analog
2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its biological activity primarily involves the inhibition of DNA synthesis and the induction of apoptosis, making it valuable for research in cancer therapy. This compound is essential for studies focusing on the mechanisms of nucleoside analogs in targeted cancer treatments. -
Cytidine Analog
N-(1-Oxopropyl)cytidine is a cytidine analog that serves as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research. Its ability to alter epigenetic regulation provides insights into gene expression modulation and therapeutic strategies in oncology. -
Purine Nucleoside Analog
2’-O-Methyl-5-methyl-4-thiouridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological effects are attributed to mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable in cancer research for exploring therapeutic strategies and understanding the cellular processes involved in tumorigenesis.
