Fig. 1 · Structure
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1,2'-O-Dimethylguanosine
Guanosine Analog
1,2'-O-Dimethylguanosine is a guanosine analogue that primarily targets Toll-like receptor 7 (TLR7). It exhibits immunostimulatory activities and has been shown to induce type I interferons in certain animal models, leading to antiviral effects. This compound serves as a valuable tool in research focused on innate immunity and therapeutic applications in viral infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 73667-71-7 |
| Applications | Guanosine Analog |
| Formula | C12H17N5O5 |
| Molecular Weight | 311.29 |
| SMILES | OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N(C=N2)C3=C2C(N(C)C(N)=N3)=O)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.