Fig. 1 · Structure

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3’-O-MOE-G(iBu)-2’-phosphoramidite

Guanosine Analog

3'-O-MOE-G(iBu)-2'-phosphoramidite is a guanosine analog that targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity, which can lead to the induction of type I interferons in various animal models, thereby generating antiviral effects. Its unique properties make it valuable for research applications focused on immune response and antiviral therapies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 256224-06-3
Applications Guanosine Analog
Formula C47H60N7O10P
Molecular Weight 913.99
SMILES
COCCO[C@H]1[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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