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2’-dG (iBu)-2’-phosphoramidite

Purine Nucleoside Analog

2’-dG (iBu)-2’-phosphoramidite is a purine nucleoside analog that selectively targets DNA synthesis pathways. It exhibits significant antitumor activity against indolent lymphoid malignancies through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. This reagent is essential for research applications focused on cancer biology and nucleic acid synthesis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	157327-97-4
Applications	Purine Nucleoside Analog
Formula	C₄₅H₅₅N₆O₈P
Molecular Weight	838.93
SMILES	O=C1NC(NC(C(C)C)=O)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C[C@H]3OP(OCCC#N)C(C(C)C)C(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.