Catalog No.
Product Name
Application
Product Information
Citations
-
Stable Isotope
L-(-)-Sorbose-13C-2 is a stable isotope-labeled form of (3S,4R,5S)-1,3,4,5,6-pentahydroxyhexan-2-one, which serves as an endogenous metabolite. The incorporation of the 13C label allows for precise tracking in metabolic studies and bioanalytical applications. This reagent is valuable for researchers investigating carbohydrate metabolism, metabolic pathways, and kinetics of enzymatic reactions involving sorbose derivatives. -
Stable Isotope
Cholesterol-18O is a stable isotope-labeled form of cholesterol, a crucial sterol in mammalian biology. It constitutes approximately 20-25% of the plasma membrane's structural components, influencing membrane fluidity and permeability. This compound is vital for studies on membrane dynamics, neuronal signaling, and transport protein function, as well as for investigating cholesterol's role as an endogenous agonist of estrogen-related receptor α (ERRα). Cholesterol-18O serves as a valuable tool for tracing metabolic pathways and examining lipid dynamics in various biological systems. -
Stable Isotope
L-Aspartic acid-15N,d3 is a stable isotope-labeled form of L-Aspartic acid, incorporating deuterium and nitrogen-15. This amino acid is known for its ability to penetrate the blood-brain barrier and is frequently employed in the development of prodrugs targeting colon and cecal tissues. Additionally, L-Aspartic acid is utilized in research on inflammatory conditions, providing insights into metabolic pathways and cellular responses in various biological contexts. -
Stable Isotope
4-Methoxybenzaldehyde-d1 is a deuterium-labeled analogue of 4-Methoxybenzaldehyde, a naturally occurring aromatic compound known for its distinct fragrance. This reagent is utilized in stable isotope labeling studies to elucidate the metabolic pathways and biological interactions of phenolic compounds. Research applications include investigations into its potential neurotoxic effects, including mortality and behavioral responses in various organisms, making it valuable for studies in environmental toxicology and plant chemistry. -
Stable Isotope
7-Hydroxy coumarin sulfate-d5 potassium is a deuterated stable isotope of 7-Hydroxy coumarin sulfate potassium, which serves as a metabolite of 7-Ethoxycoumarin. This compound is utilized in various research applications, including metabolic studies and tracing mechanisms of drug metabolism. Its stable isotope labeling facilitates accurate quantification and identification in biological samples, proving essential for understanding biochemical pathways and pharmacokinetics. -
Stable Isotope
D-Ribose-d-3 is a deuterium-labeled form of D-Ribose, primarily utilized as a stable isotope in biochemical research. It serves as a critical sugar moiety of adenosine triphosphate (ATP), playing a significant role in cellular energy metabolism. D-Ribose-d-3 is frequently used in studies focusing on metabolic therapies, particularly for conditions such as chronic fatigue syndrome and cardiac energy metabolism. Its incorporation in research aids in understanding metabolic pathways and energy production at the molecular level. -
Stable Isotope
Cholestenone-d7 is a deuterium-labeled variant of Cholestenone (4-Cholesten-3-one), which serves as a stable isotope for research applications. It is primarily involved in the metabolic pathways of cholesterol, particularly in the liver. Due to its high mobility within membrane systems, Cholestenone-d7 plays a significant role in studies of cholesterol dynamics and membrane transport mechanisms. This reagent is essential for understanding cholesterol metabolism and developing related therapeutic approaches. -
Stable Isotope
(±)-1,2-Propanediol-d2 is a deuterium-labeled form of (±)-1,2-Propanediol, a versatile aliphatic alcohol. This stable isotope is commonly utilized as an excipient in various formulations to enhance solubility and stability of active compounds. Its incorporation in research allows for advanced studies in pharmacokinetics and metabolic processes. -
Stable Isotope
Xylose-d-3 is a deuterium-labeled form of xylose, a five-carbon sugar. This stable isotope is primarily used as a tracer in metabolic studies and glycoprotein synthesis investigations. Its incorporation into biological systems allows for the assessment of carbohydrate metabolism and the dynamics of glycan structures in various research applications. -
Stable Isotope
Carbamazepine 10,11-epoxide-13C,d2 is a deuterated stable isotope of the active metabolite Carbamazepine 10,11-epoxide. This compound plays a crucial role in understanding the pharmacokinetics of Carbamazepine, an established anticonvulsant agent used for the treatment of epilepsy. Its use in research enables precise tracking of the drug's metabolic pathways and assessing its therapeutic efficacy in seizure management. -
Stable Isotope
D-Sorbitol-d-2 is a deuterium-labeled form of D-Sorbitol, a six-carbon sugar alcohol utilized as a sugar substitute. This compound serves as a stabilizing excipient, isotonicity agent, sweetener, humectant, and thickener in various formulations. Its unique isotopic labeling allows for enhanced tracking in metabolic studies and other research applications involving carbohydrate metabolism. D-Sorbitol-d-2 is essential for studies utilizing stable isotope labeling techniques. -
Stable Isotope
3-Pyridylacetic acid-d4 hydrochloride is a deuterated derivative of 3-Pyridylacetic acid hydrochloride. This stable isotope is utilized in various research applications, particularly in studies involving the metabolic pathways of nicotine and other tobacco alkaloids. Its incorporation into experimental designs facilitates quantitative analysis and tracking of biological processes involving pyridine derivatives. -
Stable Isotope
1-Hydroxyoctadecane-d37 is a deuterated stable isotope of 1-Hydroxyoctadecane, an endogenous metabolite involved in various biological processes. This reagent serves as an essential tool for metabolic studies and quantitative analysis in biochemical research. Its isotopic labeling enables precise tracking and identification in complex biological systems, facilitating advancements in metabolomics and related fields. -
Stable Isotope
D-Mannose-d-3 is a deuterated form of D-Mannose, a pivotal carbohydrate involved in human metabolism. It participates in the glycosylation of specific proteins, impacting various biological processes. This stable isotope is valuable for metabolic studies and tracer experiments, providing insights into carbohydrate metabolism and related pathways. -
Stable Isotope
N1,N8-Diacetylspermidine-d6 is a deuterium-labeled analogue of N1,N8-Diacetylspermidine, serving as a stable isotope tracer in biochemical research. This compound is involved in polyamine metabolism and is found in human urine, making it a valuable biomarker in studies related to cancer. Its application as a prognostic indicator facilitates the monitoring of treatment responses and follow-up examinations in cancer patients. -
Stable Isotope
1-Hexadecanol-d4 is a deuterated form of 1-Hexadecanol, a fatty alcohol characterized by its lipophilic properties. This stable isotope is essential for metabolic studies, allowing for the tracing and quantification of lipid metabolism pathways in biological systems. It is widely used in research applications related to lipid biochemistry and fatty acid metabolism. -
Stable Isotope
N-Acetyl-D-glucosamine-13C3,15N is a stable isotope-labeled form of N-Acetyl-D-glucosamine, featuring three carbon-13 and one nitrogen-15 isotopes. As a derivative of glucosamine, it serves as a critical intermediate in the synthesis of glycosaminoglycans and is involved in various biological processes, including cell signaling and metabolism. This reagent is essential for studies in metabolic tracing, structural biology, and the investigation of glycan interactions in cellular systems. -
Stable Isotope
Stearic acid-9,10-d2 is a deuterium-labeled variant of stearic acid. As a long-chain saturated fatty acid, stearic acid is commonly found in various animal and vegetable fats and oils. This stable isotope is utilized in metabolic studies, tracing fatty acid metabolism, and understanding lipid dynamics in biological systems. Its unique labeling enables precise tracking of stearic acid and its derivatives in research applications. -
Stable Isotope
DPPC-d66 is a deuterium-labeled form of di-palmitoylphosphatidylcholine (DPPC), a zwitterionic phosphoglyceride. This compound is primarily utilized in the preparation of liposomal monolayers, facilitating studies on lipid bilayer properties. DPPC-liposomes are effective delivery vehicles that enhance immune responses against glycosphingolipid (GSL) antigens, making them valuable in immunological research and drug delivery applications. -
Stable Isotope
Indole-13C8,15N is a stable isotope-labeled variant of indole, featuring both carbon-13 and nitrogen-15 isotopes. Indole, an endogenous metabolite, plays a crucial role in various biochemical processes, including tryptophan metabolism and neurotransmitter synthesis. This reagent is valuable for metabolic studies, isotopic tracer experiments, and elucidating metabolic pathways involving indole and its derivatives. -
Stable Isotope
Thyminose-13C-2 is a stable isotope variant of thyminose, an endogenous metabolite integral to nucleic acid synthesis. This compound serves as a valuable tracer in metabolic studies, allowing researchers to investigate metabolic pathways and nucleotide metabolism in biological systems. Its unique isotopic labeling enables precise tracking and quantification in various applications, including cellular metabolism and biochemistry research. -
Stable Isotope
L-Alanine-1-13C,15N is a stable isotope-labeled form of the non-essential amino acid L-Alanine, incorporating both 13C and 15N isotopes. This compound plays a crucial role in metabolic processes, including sugar and acid metabolism, and is vital for energy production in muscle tissue and the central nervous system. It is widely utilized in biological research, particularly in metabolic tracing studies, to investigate cellular metabolism and amino acid dynamics. -
Stable Isotope
D-Arabitol-d7 is a deuterated form of the natural polyol D-Arabitol, serving as a stable isotope for various research applications. Its chemical structure allows for precise tracking and quantification in metabolic studies. D-Arabitol has been implicated in neurotoxic effects when accumulated in humans, making this compound valuable for investigating its biological impact and mechanisms in neurobiology and toxicology research. -
Isotope Label
Acetylvaline-15N is a nitrogen-15 labeled derivative of acetylvaline, classified as an N-acetylated amino acid. This isotope-labeled compound serves as a valuable biomarker for the detection of maple syrup urine disease (MSUD), as its urinary excretion is significantly altered in affected individuals. Acetylvaline-15N is essential for metabolic studies and can facilitate research into amino acid metabolism disorders. -
Stable Isotope
Propane-1,2,3-triyl tripalmitate-13C3-1 is a stable isotope-labeled compound of Propane-1,2,3-triyl tripalmitate, an endogenous metabolite. This reagent serves as a valuable tracer in metabolic studies, enabling researchers to investigate lipid metabolism and associated pathways. Its stable carbon isotopic composition allows for precise quantification and tracking in biological systems, facilitating advanced research in metabolic flux analysis and biomarker discovery. -
Stable Isotope
Deltamethrin-d5 is a deuterium-labeled analog of Deltamethrin, a neurotoxic pyrethroid insecticide known for its efficacy in pest control. This stable isotope variant is primarily used in analytical studies to trace the metabolic pathways and environmental fate of Deltamethrin. It serves as a valuable tool in toxicological research, allowing for detailed investigations into the compound's neurological effects, such as induced motor symptoms in animal models. -
Stable Isotope
D-Fructose-d2-1 is a stable isotope-labeled form of D-Fructose, a naturally occurring monosaccharide prevalent in numerous plants. This deuterium-labeled variant is utilized in metabolic studies, allowing researchers to trace the metabolic pathways and kinetics of fructose in biological systems. Its applications extend to various fields, including biochemistry, pharmacokinetics, and nutritional research, providing valuable insights into carbohydrate metabolism and its implications in health and disease. -
Stable Isotope
L-Cysteine-d3,15N is a stable isotope-labeled form of the conditionally essential amino acid L-Cysteine, incorporating both deuterium and nitrogen-15. This compound serves as a precursor for key biological molecules such as hydrogen sulfide (H2S), glutathione, and taurine. Additionally, L-Cysteine has been shown to suppress ghrelin levels, thereby reducing appetite in both rodent models and humans, making it valuable for research in metabolic and nutritional studies. -
Stable Isotope
Stigmasterol-d5-1 is a deuterium-labeled derivative of stigmasterol, a prominent plant sterol. This compound is primarily utilized as a stable isotope for metabolic studies and tracer experiments, particularly in the investigation of lipid metabolism and cholesterol-lowering effects. Stigmasterol itself is known for its potential anti-inflammatory properties and has gained interest in the context of rheumatic disease therapies. -
Stable Isotope
Sodium 3-methyl-2-oxobutanoate-13C4,d3 is a stable isotope-labeled derivative of Sodium 3-methyl-2-oxobutanoate, featuring both deuterium and carbon-13 isotopes. This compound serves as a vital precursor to pantothenic acid in Escherichia coli, making it valuable for studies in metabolic pathways and nutrient biosynthesis. It is particularly useful in tracer experiments and isotopic labeling applications, facilitating insights into metabolic flux and cellular processes. -
Stable Isotope
DPPC-d75 is a deuterium-labeled form of dipalmitoylphosphatidylcholine (DPPC), a zwitterionic phosphoglyceride. This stable isotope is utilized primarily for characterizing lipid bilayers and assessing membrane dynamics. DPPC-d75 is particularly useful in studies involving liposomal formulations to facilitate immune responses against glycolipid antigens, making it relevant for immunological and pharmaceutical research applications. -
Stable Isotope
2'-Deoxyuridine-d2-1 is a deuterium-labeled analog of 2'-Deoxyuridine, serving as a stable isotope for research applications. This compound has been shown to increase chromosomal breakage and decrease thymidylate synthetase activity, making it valuable for studies on nucleic acid metabolism and DNA repair mechanisms. Additionally, 2'-Deoxyuridine is utilized as a precursor in the synthesis of the antiviral agent Edoxudine, highlighting its relevance in medicinal chemistry and therapeutic research. -
Stable Isotope
Suberylglycine-d2 is a deuterated form of Suberylglycine, a naturally occurring acyl glycine and a minor metabolite of fatty acids. As a stable isotope-labeled compound, it aids in elucidating metabolic pathways and studying fatty acid metabolism in various biological contexts. Suberylglycine-d2 serves as a useful tracer in mass spectrometry applications, enabling precise quantitative analysis in biochemical research. -
Stable Isotope
(S)-Campesterol-d6 is a deuterated form of (S)-Campesterol, serving as a stable isotope standard. This compound is primarily utilized in metabolic studies, tracer studies, and quantitative analysis of sterols. Its deuterium labeling facilitates precise tracking of metabolic pathways and enhances the accuracy of research in lipid biochemistry and nutritional science. -
Stable Isotope
Metolachlor-d11 is a deuterated form of Metolachlor, a selective chloroacetanilide herbicide that acts primarily by inhibiting the growth of specific annual grassy and broadleaf weeds in corn and other agricultural crops. This stable isotope variant is utilized for precise quantitative studies in environmental and agronomic research. Metolachlor-d11 provides a valuable tool for understanding the metabolism, persistence, and impact of herbicide residues in various ecosystems. -
Stable Isotope
Bifenox-d3-1 is a stable isotope-labeled form of the potent herbicide Bifenox. This compound primarily targets cellular membranes, promoting the generation of reactive oxygen species (ROS), which leads to membrane disruption and inhibition of photosynthetic processes. Bifenox-d3-1 is useful for research applications requiring tracking of Bifenox in environmental studies and metabolism investigations in plant biology. -
Stable Isotope
Ethofumesate-d5 is a deuterated form of Ethofumesate, a chiral herbicide that primarily inhibits mitosis. This compound is integral for studying the impact of Ethofumesate on photosynthesis and plant respiration in various biological research applications. Its isotopic labeling allows for precise tracking and quantification in experimental settings, aiding in the investigation of herbicide mechanisms and environmental effects. -
Stable Isotope
Norflurazon-13C,d3 is a stable isotope-labeled derivative of Norflurazon, a herbicide recognized for its ability to inhibit carotenoid biosynthesis. This compound exerts its primary action by targeting and inhibiting the enzyme phytoene desaturase, thereby disrupting the synthesis of protective pigments in plants. Norflurazon-13C,d3 serves as a valuable tool for research applications in plant physiology, herbicide mechanism studies, and environmental monitoring of herbicide interactions. -
Stable Isotope
Butachlor-d13 is a deuterium-labeled derivative of Butachlor, an acetanilide-class herbicide. This stable isotope is utilized as a selective pre-emergent herbicide, effectively controlling a variety of grasses and broadleaf weeds. Its isotopic labeling enables precise studies in environmental fate, metabolism, and interaction mechanisms in ecological and agricultural research applications. -
Stable Isotope
Bensulfuron-methyl-d6 is a stable isotope-labeled form of Bensulfuron-methyl, a sulfonylurea herbicide primarily targeting the inhibition of the acetolactate synthase enzyme. This compound exerts significant herbicidal activity against broad-leaf weeds, particularly in rice cultivation. It serves as a valuable analytical tool in environmental and agricultural research, allowing for the monitoring and quantification of Bensulfuron-methyl in various matrices. -
Stable Isotope
Isoproturon-d6-1 is a deuterium-labeled derivative of Isoproturon, a member of the phenylurea herbicide class. This stable isotope is employed in research to trace the fate and behavior of Isoproturon in environmental and agricultural studies. It is particularly useful for investigating the efficacy of Isoproturon against annual grasses and broad-leaved weeds in crops such as spring and winter wheat, winter rye, and both spring and winter barley. -
Stable Isotope
2,5-Dimethylpyrazine-d3 is a deuterated form of 2,5-Dimethylpyrazine, serving as a stable isotope tracer in various biological studies. This compound is an endogenous metabolite, making it suitable for research in metabolic pathways and biomarker identification. Its incorporation into experimental designs enables improved accuracy in quantitative analysis within pharmacokinetic and toxicological studies. -
Stable Isotope
7-Keto Cholesterol-d7 is a deuterium-labeled derivative of 7-Keto Cholesterol, serving as a stable isotope for metabolic studies. Its primary application includes tracking cholesterol metabolism in biological systems, enhancing the understanding of lipid biochemistry and related metabolic pathways. This compound is particularly useful in mass spectrometry and other analytical techniques for quantifying cholesterol levels and their metabolites. -
Stable Isotope
Cuminaldehyde-d8 is a deuterated form of cuminaldehyde, a natural aldehyde predominantly found in Cuminum cyminum. This compound exhibits inhibitory effects on alpha-synuclein fibrillation and reduces cytotoxicity, making it a valuable tool in neurodegenerative research. Additionally, cuminaldehyde demonstrates anticancer properties, contributing to its application in cancer biology studies. -
Stable Isotope
Pyridoxine-d2 is a deuterated form of Pyridoxine, a pyridine derivative known for its role in biological processes. This stable isotope is essential for studies involving metabolic pathways and biochemical analyses. Pyridoxine exhibits antioxidant properties and has shown efficacy in cellular models of Alzheimer's disease through the Nrf-2/HO-1 signaling pathway, making it a valuable tool for research in neurodegenerative disorders. -
Stable Isotope
L-Citrulline-d2 is the deuterium-labeled form of L-Citrulline, an amino acid involved in the metabolic conversion of ornithine and the arginine-citrulline pathway. This stable isotope is utilized in various biological studies, including metabolic tracing and pharmacokinetic analysis. With its unique isotope label, L-Citrulline-d2 aids researchers in elucidating metabolic pathways and the role of citrulline in nitric oxide production and cardiovascular health. -
Stable Isotope
Butyrylcarnitine-d3 hydrochloride is a deuterated form of butyrylcarnitine, serving as a stable isotope. This compound is an endogenous metabolite present in plasma, with elevated levels linked to lipid and energy metabolism disorders. Butyrylcarnitine-d3 can be utilized as a diagnostic and prognostic biomarker in various diseases, including heart failure and head and neck cancer, facilitating research in metabolic health and disease characterization. -
Stable Isotope
2-Hydroxyestradiol-d5 is a stable isotope-labeled derivative of 2-Hydroxyestradiol, a metabolite of 17β-estradiol known for its limited estrogenic activity. This compound exhibits notable antioxidant properties and has the capability to form stable DNA adducts, thereby contributing to genotoxic effects. It is utilized in research applications focusing on estrogen metabolism, oxidative stress, and the mechanisms of genotoxicity in cellular systems. -
Stable Isotope
Dodecanedioic acid-d4 is a deuterated form of dodecanedioic acid, serving as a stable isotope for research purposes. It is an orally active straight-chain dicarboxylic acid that acts as an alternative energy substrate, facilitating rapid oxidation during physical activity, which may help reduce muscle fatigue without triggering insulin secretion. Dodecanedioic acid also demonstrates blood glucose-lowering effects, making it relevant for studies on non-insulin-dependent diabetes mellitus. This compound is valuable for metabolic research and the investigation of energy metabolism in various physiological contexts. -
Stable Isotope
4-Ethylphenol-d2 is a deuterated analog of 4-Ethylphenol, a volatile phenolic compound known for its association with off-odour profiles in wine. This stable isotope variant is valuable for studying the metabolic pathways of 4-Ethylphenol, including its conversion by intestinal microbiota, such as Lactobacillus plantarum, into 4-ethylphenyl sulfate. Applications include investigating microbial fermentation processes and evaluating the sensory impact of phenolic compounds in food and beverage research.
