Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
ATP-18O4 sodium is a stable isotope-labeled form of adenosine 5'-triphosphate disodium salt (ATP). This compound plays a crucial role in energy storage and metabolism, providing metabolic energy for cellular functions and serving as a coenzyme. ATP-18O4 sodium is valuable in research related to cellular signaling, particularly in studies of immunity and inflammation, where understanding metabolic pathways is essential. -
Stable Isotope
Vitamin D2-d6 is a deuterium-labeled form of Vitamin D2 (Ergocalciferol), serving as a stable isotope for traceability in research applications. This compound is essential for studies on Vitamin D metabolism and its effects on various biological processes. It is particularly useful in pharmacokinetic studies and isotopic labeling experiments, enabling precise analysis of Vitamin D dynamics in biological systems. -
Stable Isotope
sn-Glycero-3-phosphocholine-d9 is a deuterium-labeled analog of sn-Glycero-3-phosphocholine, a key precursor in the synthesis of phospholipids in the brain. This compound enhances choline bioavailability within nervous tissue and has been associated with improved cognitive function, demonstrating a favorable safety and tolerability profile. It serves as an important tool for research focused on neurodegenerative diseases, including Alzheimer's disease and dementia, by facilitating the study of phospholipid metabolism and choline-related pathways in neurological contexts. -
Stable Isotope
Hexaenoic acid-d6 is a deuterium-labeled derivative of hexaenoic acid. This very long chain polyunsaturated fatty acid (VLCPUFA) serves as a significant component of ceramides and sphingomyelin, found in tissues such as the retina, sperm, and brain. Hexaenoic acid-d6 has potential applications in elucidating the biological roles of VLCPUFAs, particularly in the activation of protein kinase C, and may facilitate studies on lipid metabolism and signaling pathways. -
Stable Isotope
Stearic acid-d2 is a deuterium-labeled derivative of stearic acid, a long-chain saturated fatty acid found in various animal and vegetable fats. This stable isotope is valuable for biological and metabolic studies, providing insights into fatty acid metabolism and lipid biochemistry. It is commonly used in tracer studies and quantitative assessments in research applications related to nutrition and metabolic pathways. -
Stable Isotope
Progesterone-13C2 is a stable isotope-labeled form of progesterone, a steroid hormone that plays a vital role in regulating the menstrual cycle and maintaining pregnancy. This labeled compound is particularly useful in pharmacokinetic studies, metabolic research, and hormone tracking due to its ability to provide accurate data in mass spectrometry applications. Researchers can utilize Progesterone-13C2 to investigate hormone levels and metabolic pathways in various biological contexts. -
Stable Isotope
1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium is a deuterium-labeled derivative of 1,2-Dipalmitoyl-sn-glycerol 3-phosphate, a key phosphatidic acid and endogenous metabolite in humans. This stable isotope-labeled compound serves as a valuable tool for tracing metabolic pathways and studying lipid signaling. Its unique labeling enables precise quantitative analyses in various biochemical and pharmacological research applications. -
Stable Isotope
Dodecanedioic acid-d20 is a stable isotope-labeled form of Dodecanedioic acid, a straight-chain dicarboxylic acid that is orally active. It serves as an alternative energy substrate, promoting rapid oxidation during exercise, which can help alleviate muscle fatigue without inducing insulin secretion. Additionally, Dodecanedioic acid demonstrates blood glucose-lowering effects, making it relevant for studies focused on non-insulin-dependent diabetes mellitus and energy metabolism. -
Stable Isotope
Myristic acid-13C is a stable isotope-labeled version of myristic acid, a saturated fatty acid with a 14-carbon chain. It is prominently found in various animal and vegetable fats, such as butterfat, coconut oil, palm oil, and nutmeg oil. This reagent is primarily utilized in metabolic studies, lipid metabolism research, and tracing studies in biological systems to investigate fatty acid pathways and utilization. -
Stable Isotope
D(-)-2-Aminobutyric acid-d6 is a deuterated form of D(-)-2-Aminobutyric acid, serving as a stable isotope for research applications. This compound acts as a substrate for D-amino acid oxidase, facilitating studies on amino acid metabolism and its implications in various biological processes. Its isotopic labeling can enhance the analysis of metabolic pathways and improve detection in mass spectrometry-based experiments. -
Stable Isotope
(24Rac)-Campesterol-d7 is a deuterium-labeled variant of Campesterol, a plant sterol known for its cholesterol-lowering and anticarcinogenic properties. This stable isotope is ideal for use in metabolic studies, specifically those examining sterol metabolism and dietary impacts on health. Researchers can utilize (24Rac)-Campesterol-d7 to trace metabolic pathways and assess the biological effects of plant sterols in various experimental conditions. -
Stable Isotope
D-Galactose-13C-2 is a stable isotope-labeled form of D-Galactose, a natural aldohexose that serves as a C-4 epimer of glucose. This reagent is beneficial for metabolic studies, particularly in tracer experiments to analyze carbohydrate metabolism and dynamics. Its stable isotopic labeling allows for precise tracking and quantification in biological systems, making it a valuable tool for researchers investigating metabolic pathways and disease mechanisms. -
Stable Isotope
Guanidine-d5 hydrochloride is a deuterium-labeled derivative of guanidine hydrochloride, serving as a stable isotope reagent. It acts as a powerful chaotropic agent and a denaturant for proteins, facilitating the disruption of protein structures and interactions. This compound is widely utilized in biochemical and biophysical research applications, particularly in studies involving protein folding, stability assays, and mass spectrometry analysis. -
Stable Isotope
ATP-13C10,15N5 is a stable isotope-labeled form of adenosine 5'-triphosphate (ATP), incorporating 13C and 15N isotopes. ATP serves as a fundamental element in cellular energy metabolism and is crucial for driving metabolic processes and enzymatic reactions. Additionally, ATP functions as an important endogenous signaling molecule, playing significant roles in immune response and inflammation. This reagent is applicable in various research fields, including metabolic studies, cellular signaling, and bioenergetics. -
Stable Isotope
1-Palmitoyl-sn-glycero-3-phosphocholine-d49 is a deuterium-labeled derivative of the abundant lysophosphatidylcholine, 1-Palmitoyl-sn-glycero-3-phosphocholine. This stable isotope is utilized in research to investigate proinflammatory activities associated with lysophosphatidylcholines. Its applications extend to studies of atherosclerosis and other inflammatory conditions, providing insights into lipid metabolism and signaling pathways. -
Stable Isotope
Levoglucosan-13C6 is a stable isotope-labeled form of Levoglucosan (1,6-Anhydro-β-D-glucopyranose). This anhydrosugar is generated through the pyrolysis of glucan and is present in various natural sources. It serves as a valuable tool in chemical research for tracking carbohydrate metabolism and analyzing the contribution of biomass burning to environmental carbon cycling. -
Stable Isotope
Estriol-13C3 is a stable isotope-labeled form of Estriol, serving as a valuable tool in metabolic and pharmacokinetic studies. Estriol functions as an antagonist of the G-protein coupled estrogen receptor, with specific relevance in the investigation of estrogen receptor-negative breast cancer cells. This compound facilitates precise tracking and quantification in biochemical assays, supporting research in cancer biology and therapeutic development. -
Stable Isotope
1-Methylxanthine-13C4,15N3 is a stable isotope-labeled form of 1-Methylxanthine, incorporating four carbon-13 and three nitrogen-15 isotopes. As a metabolite of caffeine and theophylline, it serves as a key component in studies of purine metabolism and its associated pathways. Additionally, 1-Methylxanthine has been shown to enhance the radiosensitivity of tumor cells, making it valuable for cancer research and therapeutic studies. -
Stable Isotope
Progesterone-13C5 is a stable isotope-labeled form of progesterone, a steroid hormone integral to the regulation of the menstrual cycle and essential for maintaining pregnancy. This reagent is valuable for research applications involving metabolic studies, hormone tracking, and pharmacokinetic analyses. Its use facilitates precise quantification and tracking of progesterone in biological systems. -
Stable Isotope
Glycerol-13C-1 (90% in water) is a stable isotope-labeled derivative of glycerol. It serves as a crucial component in sample preparation and gel formation for polyacrylamide gel electrophoresis (PAGE). This isotope labeling enables enhanced tracking and analysis of metabolic pathways in various biological studies, offering valuable insights in cellular metabolism and biochemistry research applications. -
Stable Isotope
Carbamazepine 10,11 epoxide-d2 is a deuterated form of Carbamazepine 10,11 epoxide, an important active metabolite of Carbamazepine. This compound exhibits anticonvulsant properties and is primarily utilized in studies related to seizure disorders. Its stable isotope labeling facilitates advanced pharmacokinetic and metabolic research applications, providing valuable insights into the drug's mechanism of action and metabolic pathways. -
Stable Isotope
Estriol-d is a deuterium-labeled form of Estriol, serving as a stable isotope for analytical applications. This compound acts as an antagonist of G-protein coupled estrogen receptors, particularly in estrogen receptor-negative breast cancer cells. It is valuable for studying estrogen receptor signaling and the effects of hormonal modulation in cancer research. -
Stable Isotope
Trihydroxycholestanoic acid-d3 is a deuterium-labeled derivative of Trihydroxycholestanoic acid, utilized as a stable isotope for advanced biochemical studies. This compound serves as a valuable tool for tracing metabolic pathways and enhancing mass spectrometry analysis in lipid research. Its incorporation allows for precise quantitation of cholestanol metabolism and related lipid interactions, making it essential for elucidating biosynthetic pathways and disease mechanisms. -
Stable Isotope
7β-Hydroxy-4-cholesten-3-one-d7 is a stable isotope-labeled derivative of 7β-Hydroxy-4-cholesten-3-one. This compound is primarily utilized in metabolic studies and tracer experiments, aiding in the understanding of cholesterol metabolism and related pathways. Its deuterated form enhances detection sensitivity in mass spectrometry applications, making it valuable for quantitative analysis in biochemical research. -
Stable Isotope
Ternidazole-d6 hydrochloride is a deuterated analog of Ternidazole hydrochloride, a nitroimidazole derivative known for its antiprotozoal activity. This stable isotope is useful in pharmacokinetic studies, enabling precise tracking of drug metabolism and distribution in biological systems. Its application extends to research involving the investigation of drug interactions and effectiveness against protozoan infections. -
Stable Isotope
Phenyl acetate-d5 is a deuterium-labeled analog of phenyl acetate, serving as a stable isotope for analytical applications. This compound functions as an endogenous metabolite and is associated with the metabolism of glutamine. Additionally, phenyl acetate-d5 may be employed as a biomarker for specific conditions, including depression, making it valuable for research in metabolic studies and disease detection. -
Stable Isotope
1,7-Dimethyluric acid-d3 is a deuterium-labeled derivative of 1,7-Dimethyluric acid, a known metabolite of caffeine. As a stable isotope, it serves as a valuable internal standard in analytical chemistry, particularly in studies involving caffeine metabolism and pharmacokinetics. This reagent is essential for enhancing the accuracy and precision of mass spectrometry and NMR experiments in metabolic research. -
Stable Isotope
4-Methyl-2-oxopentanoic acid-d7 sodium is a deuterated derivative of 4-Methyl-2-oxopentanoic acid, a key metabolite of L-leucine. This stable isotope is instrumental in studying energy metabolism, as it influences endoplasmic reticulum stress and lipid accumulation in preadipocytes. Additionally, 4-Methyl-2-oxopentanoic acid-d7 sodium has been shown to impair mTOR and autophagy signaling pathways, making it valuable for research into insulin resistance and metabolic disorders. -
Stable Isotope
Hydroxy ipronidazole-d3 is a deuterated form of Hydroxy ipronidazole, a metabolite of nitroimidazole antibiotics, including ipronidazole. This stable isotope can be utilized in pharmacokinetic studies to trace metabolic pathways and assess the mutagenic potential of related compounds. Research applications may involve investigations into the pharmacodynamics and safety profiles of nitroimidazole derivatives. -
Stable Isotope
L-Citrulline-d6 is a deuterium-labeled form of the amino acid L-citrulline, which plays a critical role in the urea cycle and nitrogen metabolism. It is produced from ornithine during the catabolism of proline, glutamine, or glutamate, as well as from l-arginine via the arginine-citrulline pathway. This stable isotope is utilized in metabolic studies, tracer experiments, and to track metabolic processes involving L-citrulline. It is valuable for research in biochemical and physiological studies related to nitric oxide synthesis and vascular health. -
Stable Isotope
Decanedioic acid-d4 is a deuterium-labeled derivative of decanedioic acid, a straight-chain dicarboxylic acid. This compound has been shown to effectively address metabolic inflexibility in type 2 diabetes and is implicated in the prevention and reversal of metabolic-associated liver disease and obesity. Additionally, decanedioic acid is relevant in studying carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency, making it a valuable tool for research in metabolic disorders. -
Stable Isotope
Allotetrahydrocortisol-d5 is a deuterium-labeled analog of allotetrahydrocortisol, a metabolite of cortisol. As the primary glucocorticoid in humans, cortisol is synthesized in the adrenal cortex and is essential in regulating various physiological processes, including metabolism, immune response, and stress adaptation. Allotetrahydrocortisol-d5 serves as a stable isotope standard for quantitative analysis in metabolic studies and pharmacokinetic research, enabling researchers to accurately trace cortisol metabolism and its biological effects. -
Stable Isotope
p-Toluic acid-d4 is a deuterium-labeled derivative of p-Toluic acid, a substituted benzoic acid. This stable isotope serves as an important intermediate in the synthesis of various compounds, including para-aminomethylbenzoic acid (PAMBA) and p-tolunitrile. Its applications extend to studies involving metabolic pathways and the characterization of reaction mechanisms in chemical research. -
Stable Isotope
Vanillylmandelic acid-d is a deuterated form of Vanillylmandelic acid, a stable isotope commonly utilized in metabolic studies. As a key metabolite of epinephrine and norepinephrine, it serves as a biomarker for disruptions in neurotransmitter metabolism. Additionally, Vanillylmandelic acid exhibits antioxidant properties, effectively scavenging DPPH radicals with an IC50 of 33 μM, making it valuable for research involving oxidative stress and neuronal health. -
Stable Isotope
L-Leucine-d is the deuterium-labeled form of L-Leucine, an essential branched-chain amino acid (BCAA) that activates the mTOR signaling pathway. This stable isotope enables the study of metabolic processes and protein synthesis, providing insights into cellular function and regulatory mechanisms. L-Leucine-d is valuable for research applications in nutrition, metabolism, and muscle physiology. -
Stable Isotope
4-O-Methyldopa-d3 is a deuterium-labeled analog of 4-O-Methyldopamine. This stable isotope is utilized primarily in pharmacokinetic studies and metabolic research to trace the dynamics of neurochemical processes. Its applications include the investigation of dopaminergic signaling pathways and the study of drug metabolism and disposition. -
Stable Isotope
5-Methyluridine-5′-13C is a stable isotope-labeled form of 5-Methyluridine, which is an endogenous methylated nucleoside commonly found in human biology. This reagent serves as a valuable tool for metabolic studies and tracer experiments, enabling researchers to track nucleoside metabolism and its effects in various biological systems. It is particularly useful in investigating RNA methylation mechanisms and studying the role of nucleosides in cellular processes. -
Stable Isotope
Vitamin K1-d3 (Phylloquinone-d3; Phytomenadione-d3) is a deuterium-labeled variant of Vitamin K1. This stable isotope is utilized in metabolic studies and tracer experiments to investigate Vitamin K1 dynamics in biological systems. Its isotopic labeling allows for precise quantification and tracking of Vitamin K metabolism, thus aiding research on its physiological roles and potential therapeutic applications. -
Stable Isotope
(R)-Pyrrolidine-2-carboxylic acid-d3 is a deuterium-labeled form of (R)-pyrrolidine-2-carboxylic acid, an important endogenous metabolite. This stable isotope is utilized in metabolic studies and tracer experiments, providing insights into biochemical pathways. Its accurate labeling enhances the detection and quantification of metabolites in various biological samples, facilitating research in metabolism and related fields. -
Stable Isotope
D-Ribose-18O is a stable isotope-labeled form of D-Ribose, a critical sugar moiety in adenosine triphosphate (ATP) synthesis. This compound serves as an energy enhancer and is utilized in metabolic therapy, particularly for conditions like chronic fatigue syndrome and cardiac energy metabolism. Additionally, D-Ribose plays a role in protein glycation studies, making it valuable for research in metabolic pathways and energy regulation. -
Stable Isotope
3-Hydroxybutyric acid-d2 sodium is a stable isotope-labeled derivative of 3-Hydroxybutyric acid sodium, a key metabolite associated with type I diabetes. This compound exhibits noteworthy effects on membrane lipid properties, making it a valuable tool for studying metabolic pathways and lipid interactions. Its use in research facilitates the investigation of metabolic disorders and the role of ketone bodies in energy metabolism. -
Stable Isotope
2'-Deoxyuridine-5′-13C is a stable isotope-labeled form of 2'-Deoxyuridine. This compound is known to enhance chromosome breakage and reduce thymidylate synthase activity, making it a valuable tool for studying DNA synthesis and repair mechanisms. Its applications extend to the synthesis of nucleoside analogs such as Edoxudine, facilitating research in cancer and antiviral therapies. -
Stable Isotope
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d70 is a deuterium-labeled derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE), a phosphoethanolamine (PE) lipid. This stable isotope is utilized in biochemical research to track lipid metabolism and dynamics within biological systems. Its applications include the formulation of liposomes and nanoparticles for drug delivery, as well as the study of membrane protein interactions and lipid signaling pathways. -
Stable Isotope
Vitamin K1-d4 is a deuterated form of Vitamin K1, serving as a stable isotope. This compound is essential for various biological processes, including blood coagulation and the metabolism of bone and vascular tissues. It is widely used in research applications involving metabolic tracing and the study of vitamin K dynamics in biological systems. -
Stable Isotope
D-Glycerol-13C-3 is a stable isotope-labeled form of D-Glycerol, featuring three carbon-13 isotopes. This compound is utilized in metabolic studies and tracer experiments, enabling the examination of glycerol metabolism and its incorporation into various biochemical pathways. It serves as a valuable tool for researchers investigating metabolic flux analysis and isotopic labeling in cellular studies. -
Stable Isotope
L-Alanine-2-13C is a stable isotope-labeled form of L-Alanine, a non-essential amino acid crucial for various metabolic processes, including glucose metabolism and nitrogen balance. It plays a significant role in energy production for muscle tissue and the central nervous system, as well as in enhancing immune function. This reagent is valuable for research applications in metabolic studies, tracer experiments, and protein synthesis investigations. -
Stable Isotope
Thyminose-13C-1 is a stable isotope-labeled version of thyminose, an endogenous metabolite involved in various biochemical pathways. This compound is utilized in metabolic studies and isotope labeling experiments, providing insights into metabolic processes and cellular functions. The incorporation of 13C allows for enhanced tracking and quantification in biological systems, facilitating advanced research in metabolic flux analysis and related areas. -
Stable Isotope
Bisphenol A-d4-1 is a deuterated analog of Bisphenol A, primarily utilized as a stable isotope for tracing and analytical applications. This compound is significant in research due to its role as an endocrine-disrupting chemical, associated with various health implications such as reproductive and developmental toxicities. It is commonly employed in studies investigating the effects of environmental contaminants on human health and disease, particularly within the fields of toxicology and endocrine research. -
Stable Isotope
D-Galactose-d-1 is a deuterium-labeled derivative of D-Galactose, a naturally occurring aldohexose and C-4 epimer of glucose. This stable isotope is widely utilized in metabolic studies, particularly in tracer experiments for glycan analysis and carbohydrate metabolism. Its incorporation into various biological systems enhances the understanding of metabolic pathways and the role of sugars in cellular processes. -
Stable Isotope
2'-Deoxyuridine-3′-13C is a stable isotope-labeled analog of 2'-Deoxyuridine, featuring a carbon-13 isotope at the 3' position. This compound can lead to increased chromosome breakage and a reduction in thymidylate synthetase activity, making it a valuable tool in studies of nucleic acid metabolism and repair mechanisms. It is also utilized as a precursor in the synthesis of various pharmaceuticals, including Edoxudine, enhancing its applicability in biochemical research.
