Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
Propionyl-L-carnitine-d3 hydrochloride is a deuterium-labeled derivative of Propionyl-L-carnitine, targeting muscular carnitine transferase with high affinity. This compound enhances cellular carnitine levels, facilitating the transport of free fatty acids into mitochondria. Research has demonstrated its application in alleviating the symptoms of peripheral artery disease (PAD) and improving exercise performance through its metabolic pathways. -
Stable Isotope
D-Glucose-d1-4 is a deuterium-labeled derivative of D-Glucose, a fundamental monosaccharide involved in various metabolic processes. This stable isotope serves as a valuable tracer in metabolic studies, enabling researchers to investigate carbohydrate metabolism, flux analysis, and signaling pathways. Its unique labeling allows for enhanced tracking of D-Glucose in biological systems, making it a versatile tool for studying cellular responses to metabolic changes and stress conditions. -
Stable Isotope
Rhamnose-13C monohydrate is a stable isotope-labeled form of the naturally occurring monosaccharide, rhamnose. This compound is primarily utilized in metabolic studies, tracing sugar metabolism, and in the development of rhamnose-conjugated immunogens for immunotherapy applications. Its unique isotopic signature allows for detailed analysis in various biological research contexts, particularly in plant and bacterial studies. -
Stable Isotope
L-Isoleucine-13C6,15N,d10 is a stable isotope-labeled variant of the essential amino acid L-Isoleucine, incorporating deuterium and carbon-13 as well as nitrogen-15. As a nonpolar hydrophobic amino acid, L-Isoleucine plays a crucial role in protein synthesis and metabolism. This labeled compound is useful in metabolic studies, tracer experiments, and applications in proteomics for tracking amino acid incorporation and behavior in biological systems. -
Stable Isotope
Calcifediol-d6 monohydrate is a deuterated form of Calcifediol monohydrate, serving as a stable isotope for research applications. As a potent ligand for vitamin D receptors (VDR), Calcifediol plays a crucial role in the vitamin D endocrine system, being hydroxylated in the liver to yield calcitriol, the biologically active form of vitamin D. This compound is instrumental in studies analyzing vitamin D metabolism, its role in calcium homeostasis, and potential therapeutic applications in various health conditions related to vitamin D deficiency. -
Stable Isotope
4-Ethylphenol-d10 is a deuterated analog of 4-Ethylphenol, a volatile phenolic compound that contributes to off-odors in wine. This stable isotope is useful for tracing studies involving aromatic compounds, particularly in the context of microbiota metabolism, as it is synthesized by intestinal flora. Research applications include studying metabolic pathways and microbial activity, specifically regarding the conversion to 4-ethylphenyl sulfate by Lactobacillus plantarum. -
Stable Isotope
2-(2-Methylbenzamido)acetic acid-d7 is a deuterated stable isotope of 2-(2-Methylbenzamido)acetic acid. This compound serves as a valuable internal standard in mass spectrometry applications for the quantitative analysis of metabolites. It is particularly useful for tracing metabolic pathways and studying renal excretion profiles, enhancing the accuracy of biochemical research involving this metabolite. -
Stable Isotope
Myristic acid-d2 is the deuterium-labeled form of myristic acid, a saturated 14-carbon fatty acid. It is commonly found in various animal and vegetable fats, particularly in butterfat, coconut oil, palm oil, and nutmeg oil. This stable isotope is primarily used in metabolic studies and tracers in fatty acid metabolism research, facilitating investigations into lipid biochemistry and metabolic pathways. -
Stable Isotope
H-D-Trp-OH-d5 is a deuterium-labeled derivative of D-Tryptophan, which is the D-stereoisomer of tryptophan. This stable isotope is utilized in various biochemical applications, including metabolic studies and tracer experiments, to trace the incorporation of tryptophan into biological systems. Additionally, H-D-Trp-OH-d5 can be valuable in investigating peptide structures and functions, particularly in the context of naturally occurring peptides such as marine venom peptides. -
Stable Isotope
Hexacosanoic acid-d3 is a deuterium-labeled form of hexacosanoic acid, classified as a very long-chain fatty acid. This stable isotope is utilized primarily in metabolic research and can help elucidate the metabolic pathways of fatty acids in various biological systems. Abnormal levels of hexacosanoic acid have been linked to several diseases, including X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia, making it valuable for studies in disease mechanisms and biomarker development. -
Stable Isotope
Cytosine-13C,15N2 is a stable isotope-labeled derivative of cytosine, marked by the incorporation of 13C and 15N isotopes. As one of the primary nucleobases in DNA and RNA, cytosine plays a crucial role in genetic information storage and expression. This compound is valuable for studying epigenetic modifications and their circadian oscillations, providing insights into mechanisms underlying epigenetic diversity and aging processes in biological systems. -
Stable Isotope
DPPC-d9-1 is a deuterium-labeled derivative of dipalmitoylphosphatidylcholine (DPPC), a zwitterionic phosphoglyceride. This stable isotope is utilized in the formation of liposomal monolayers, enhancing its utility in membrane studies. DPPC-based liposomes are effective delivery vehicles in eliciting immune responses targeting glycosphingolipid antigens in murine models, making it valuable for immunological research and drug delivery applications. -
Stable Isotope
Oleoylcarnitine-d9 is a deuterium-labeled derivative of Oleoylcarnitine, a metabolite involved in the inhibition of fatty acid β-oxidation. This compound has been shown to promote hepatocarcinogenesis through the activation of the STAT3 signaling pathway. Oleoylcarnitine-d9 serves as a stable isotope for metabolic studies, enabling researchers to investigate lipid metabolism and related oncogenic processes in various biological systems. -
Stable Isotope
Hexacosanoic acid-d4-1 is a deuterium-labeled stable isotope of Hexacosanoic acid, a very long-chain fatty acid. Elevated levels of Hexacosanoic acid are associated with several pathological conditions, including X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia. This reagent is valuable for biological research and analytical applications, particularly in the study of fatty acid metabolism and disease mechanisms. -
Stable Isotope
L-Tyrosine-d2-2 is a deuterium-labeled form of the non-essential amino acid L-Tyrosine. This compound serves as a stable isotope, enabling advanced metabolic studies and tracing applications. L-Tyrosine plays a role in inhibiting citrate synthase activity, particularly in the posterior cortex, making it valuable for research in neurobiology and metabolism. -
Stable Isotope
(Rac)-Cotinine-d4 is a stable isotope-labeled variant of (Rac)-Cotinine, featuring deuterium substitution. This reagent serves as a valuable tool in pharmacokinetic studies and metabolic profiling of nicotine metabolism. Its unique isotopic signature allows for accurate quantification in biological samples, aiding in research related to nicotine's effects and the development of smoking cessation therapies. -
Stable Isotope
Arachidonic acid-d5 is a deuterium-labeled derivative of arachidonic acid, a crucial polyunsaturated fatty acid involved in the biosynthesis of eicosanoids. This stable isotope is primarily utilized in metabolic and biochemical research to investigate lipid metabolism, signaling pathways, and the role of arachidonic acid in physiological processes. Its incorporation into studies enhances the understanding of fatty acid dynamics and their functional implications in health and disease. -
Stable Isotope
L-Histidine-13C6,15N3 is a stable isotope-labeled variant of L-Histidine, incorporating six carbon-13 and three nitrogen-15 atoms. This essential amino acid is crucial for growth and development, particularly in infants. In addition to serving as a building block for proteins, L-Histidine-13C6,15N3 acts as an inhibitor of mitochondrial glutamine transport, making it valuable for research in metabolic studies and amino acid transport mechanisms. -
Stable Isotope
Tristearin-d5 is a deuterium-labeled derivative of tristearin, a triglyceride composed of three stearic acid molecules. This stable isotope is utilized in metabolic studies and tracer experiments to investigate lipid metabolism, as well as to trace lipid pathways in biological systems. Its applications extend to research in pharmacokinetics and the biological effects of triglycerides in various cellular contexts. -
Stable Isotope
(±)-1,2-Propanediol-d6 is a deuterium-labeled form of (±)-1,2-Propanediol, an aliphatic alcohol. This stable isotope is commonly employed as an excipient to enhance the solubility and stability of various formulations in chemical research. Its unique properties make it suitable for applications in pharmacokinetics, metabolism studies, and isotopic tracing in biological systems. -
Stable Isotope
Uracil-13C2,15N2 is a stable isotope-labeled form of uracil, incorporating two carbon-13 and two nitrogen-15 atoms. As a naturally occurring pyrimidine derivative, uracil plays a critical role as one of the four nucleobases in RNA molecules. This isotopically labeled compound is valuable for metabolic and pharmacokinetic studies, allowing researchers to track the incorporation and metabolism of nucleobases in biological systems. Its use enhances understanding of RNA dynamics and cellular processes in various research applications. -
Stable Isotope
DL-Homocysteine thiolactone-d4 hydrochloride is a deuterium-labeled derivative of DL-Homocysteine thiolactone, serving as a stable isotope reagent. This compound acts as a cyclic amino acid derivative and is known for its root-growth inhibitory activity. It is primarily utilized in chemical research applications to study homocysteine metabolism and its implications in various biological processes. -
Stable Isotope
Tricaprilin-13C3 is a stable isotope-labeled medium-chain triglyceride (MCT) that serves as a valuable tool for metabolic research. It is primarily used to induce ketosis, promoting brain electrical activity and metabolism while addressing neuroinflammation associated with migraines. Tricaprilin holds potential in studies related to migraine prevention and Alzheimer’s disease, offering insights into the therapeutic effects of ketogenic agents. This compound is characterized by its pure C8 structure, making it essential for exploring metabolic pathways in various neurological conditions. -
Stable Isotope
Alpha-D-glucose-13C is a stable isotope-labeled form of alpha-D-glucose, an endogenous carbohydrate. This isotopic variant serves as a valuable tracer in metabolic studies, allowing researchers to investigate glucose metabolism and various biochemical pathways. Its application is crucial in nutrition research, metabolic flux analysis, and studies on energy production within cells. -
Stable Isotope
Palmitoleic acid-d14 is a stable isotope-labeled form of palmitoleic acid. This unsaturated fatty acid serves as an important biomolecule involved in metabolic regulation and cell signaling. Palmitoleic acid-d14 is utilized in research to study fatty acid metabolism and its effects on various pathological conditions, including cerebrovascular disorders. Its stable isotopic labeling aids in precise tracking and quantification in biochemical analyses. -
Stable Isotope
Phosphorylethanolamine-d4 is a deuterated form of Phosphorylethanolamine, serving as a stable isotope for research applications. This compound is an endogenous metabolite involved in various biological processes, including cell signaling and metabolism. It is particularly useful in mass spectrometry and isotopic labeling studies, enabling precise tracking of metabolic pathways and biochemical interactions in biological systems. -
Stable Isotope
Phenoxyacetic acid-d5 is a deuterated form of Phenoxyacetic acid, an important endogenous metabolite. As a stable isotope, it serves as a valuable tool for tracing metabolic pathways in biological research. Its applications include quantitative analysis in pharmacokinetics and the study of metabolic processes in various biological systems. -
Stable Isotope
D-Ribose-5,5-C-d2 is a deuterium-labeled form of D-Ribose, a critical sugar moiety involved in the synthesis of ATP. This stable isotope serves as a valuable tool in metabolic studies, particularly in evaluating energy metabolism and therapeutic approaches for conditions such as chronic fatigue syndrome and cardiac dysfunction. Its application enhances understanding of metabolic pathways and cellular energy production in biological research. -
Stable Isotope
3α,7α-Dihydroxycoprostanic acid-d3 is a stable isotope-labeled form of the endogenous metabolite 3α,7α-Dihydroxycoprostanic acid. As a bile acid, it serves as a precursor to chenodeoxycholic acid, playing a crucial role in the regulation of bile acid metabolism. This stable isotope can be utilized in research applications involving metabolic studies and tracing pathways of bile acid synthesis and degradation. -
Stable Isotope
Linoleic acid-13C1 is a stable isotope-labeled form of linoleic acid, a polyunsaturated fatty acid found in plant oils, nuts, and seeds. It plays a critical role in membrane phospholipid composition and is essential for maintaining membrane fluidity in cellular structures, particularly in the epidermal water barrier. This reagent is valuable for investigating metabolic pathways and oxidative stress mechanisms, particularly in studies related to red blood cell health and hemoglobin stability. -
Stable Isotope
Tristearin-d40 is a deuterium-labeled form of Tristearin, a triglyceride composed of three stearic acid molecules. This stable isotope is primarily used as a tracer in metabolic studies and lipid research, allowing for the quantification and analysis of triglyceride metabolism. Its unique isotopic signature makes it valuable for investigating lipid dynamics and metabolic pathways in biological samples. -
Stable Isotope
N-Acetyl-D-glucosamine-15N is a stable isotope-labeled derivative of N-Acetyl-D-glucosamine, a monosaccharide. This compound is primarily used as a tracer in metabolic studies to investigate the roles of glycosaminoglycans and glycoproteins in biological systems. Its unique isotopic labeling enables precise quantification in various analytical techniques, including mass spectrometry. N-Acetyl-D-glucosamine-15N is essential in biochemical research focused on carbohydrate metabolism and cellular processes. -
Stable Isotope
N-Palmitoyl-D-sphingomyelin-d9 is a deuterium-labeled variant of N-Palmitoyl-D-sphingomyelin, also known as Sphingomyelin 16:0-d9. This stable isotope serves as a crucial component in the synthesis of lipid nanoparticles, enabling researchers to track and study lipid behaviors in biological systems. Its unique properties make it valuable for various applications in lipid research, membrane biology, and drug delivery development. -
Stable Isotope
Pyruvic acid-13C,d4 is a stable isotope-labeled form of pyruvic acid, distinguished by its deuterium and carbon-13 isotopes. This molecule serves as a key intermediate in the metabolic pathways of carbohydrates, proteins, and fats. It is widely used in metabolic studies, tracer experiments, and isotopic labeling applications to investigate metabolic flux and pathways in various biological systems. -
Stable Isotope
Zymostenol-d7 is a deuterium-labeled derivative of 5α-cholest-8-en-3β-ol. As a stable isotope, it serves as a valuable internal standard in mass spectrometry and tracer studies. This compound is widely utilized in biochemical research to investigate cholesterol metabolism and related pathways. Its precise labeling facilitates accurate quantification in various analytical applications. -
Stable Isotope
Pyridoxal-d3 is a stable isotope-labeled form of pyridoxal, designed for applications in mass spectrometry and isotopic tracing studies. This compound enables the investigation of vitamin B6 metabolism and biochemical pathways with enhanced sensitivity and accuracy. Its incorporation into research allows for precise quantification of pyridoxal derivatives in various biological samples. -
Stable Isotope
Isovaleric acid-d2 is the deuterated form of isovaleric acid, a natural fatty acid with significant biological relevance. As a stable isotope, it is primarily utilized in metabolic and pharmacokinetic studies to trace the pathways and interactions of isovaleric acid in biological systems. This compound serves as an important tool for investigating its effects in various research applications, including studies on neonatal health and metabolic disorders. -
Stable Isotope
Phenylglyoxylic acid-d5 sodium is a deuterated metabolite of ethylbenzene and styrene, serving as a stable isotope for analytical applications. This compound is a valuable biomarker for assessing human exposure to ethylbenzene and styrene. Additionally, it functions as an important intermediate in the synthesis of antineoplastic agents, facilitating research in cancer therapeutics. -
Stable Isotope
Stearic acid-1-13C is a stable isotope-labeled form of stearic acid, a long-chain saturated fatty acid commonly found in various animal and plant fats and oils. This compound serves as a valuable tool in metabolic research and lipid studies, enabling precise tracking of fatty acid metabolism and its incorporation into biological systems. Its use is essential for elucidating the roles of fatty acids in cellular processes and investigating lipid-related diseases. -
Stable Isotope
Trimethylammonium chloride-d6 is a deuterium-labeled derivative of Trimethylammonium chloride. This stable isotope serves as a valuable tool in metabolomics studies and chemical tracing applications. Its use enables precise tracking of metabolic pathways and provides insights into metabolic processes in various biological systems. -
Stable Isotope
(2RS,4R,8R)-δ-Tocopherol-d4 (Mixture of Diastereomers) is a stable isotope-labeled derivative of delta-tocopherol. This compound serves as a critical tool for studying tocopherol metabolism, tracking vitamin E bioavailability, and conducting quantitative analysis in various biological systems. Its stable isotope composition enhances the accuracy of analytical techniques such as mass spectrometry, facilitating advanced research in nutritional science and biochemistry. -
Stable Isotope
Lanosterol-d6 is a deuterated form of lanosterol, a key intermediate in cholesterol biosynthesis. This stable isotope is instrumental in studying the metabolic pathways of cholesterol, as it induces the ubiquitination and degradation of HMG-CoA reductase, a rate-limiting enzyme in cholesterol synthesis. Research applications include investigating lipid metabolism and exploring mechanisms of cholesterol homeostasis. -
Stable Isotope
DL-Alanine-d3 is a deuterium-labeled stable isotope of DL-Alanine, which is the racemic form of the amino acids L- and D-alanine. This compound serves as a reducing and capping agent in nanoparticle synthesis processes, particularly with silver nitrate solutions. DL-Alanine-d3 is also valuable in studies involving the chelation of transition metals such as Cu(II), Zn(II), and Cd(II). Furthermore, it contributes to the understanding of metabolic pathways, including the glucose-alanine cycle, highlighting its importance in various biological research applications. -
Stable Isotope
Water-17O is a stable isotope of water labeled with the isotope oxygen-17. This compound is primarily employed in biochemical research, particularly in studies involving metabolic pathways and tracing experiments. Due to its unique nuclear properties, Water-17O is valuable for nuclear magnetic resonance (NMR) studies and isotope labeling applications, allowing for enhanced tracking of cellular processes and fluid dynamics in biological systems. -
Stable Isotope
Hypoxanthine-13C5,15N4 is a stable isotope-labeled form of hypoxanthine, featuring both 15N and 13C isotopes. As a purine derivative, hypoxanthine serves as a potential generator of free radicals and can be utilized as a biomarker for hypoxic conditions. This reagent is suitable for various research applications, including studies on metabolism, oxidative stress, and hypoxia-related pathways. -
Stable Isotope
Sapropterin-d3 ((6R)-BH4-d3) is a deuterium-labeled form of Sapropterin, functioning as a stable isotope. As an orally active cofactor for phenylalanine hydroxylase (PAH), it effectively lowers blood phenylalanine levels, making it valuable in research related to phenylketonuria (PKU). This reagent is essential for studies investigating metabolic pathways and therapeutic strategies related to amino acid metabolism disorders. -
Stable Isotope
Cyclohexanecarboxylic acid-d11 is a stable isotope-labeled form of cyclohexanecarboxylic acid, serving as a valuable tool in chemical research. It is a structural analogue of valproate, exhibiting anticonvulsant properties. This compound is ideal for studies involving metabolic tracing, pharmacokinetics, and understanding drug mechanisms due to its isotopic labeling. -
Stable Isotope
(Rac)-Cotinine-d3 is the deuterium-labeled analog of (Rac)-Cotinine, primarily utilized as a stable isotope for research applications. This compound serves as a valuable internal standard in mass spectrometry and pharmacokinetic studies involving nicotine metabolism and its effects. The incorporation of deuterium enhances analytical sensitivity and provides precise quantification in biological samples, making it crucial for studies in toxicology and addiction research. -
Stable Isotope
Taurodeoxycholic acid-d4 is a deuterium-labeled derivative of taurodeoxycholic acid, functioning as a stable isotope. It is utilized primarily in metabolic studies and tracer applications to investigate bile acid metabolism and digestion. This compound enhances analytical precision in studies related to lipid metabolism and liver function. -
Stable Isotope
2-Ketoglutaric acid-13C is a stable isotope-labeled derivative of 2-Ketoglutaric acid, an essential intermediate in ATP and GTP production within the Krebs cycle. This compound plays a critical role in nitrogen assimilation as a key carbon skeleton and serves as a reversible inhibitor of tyrosinase. Its applications include metabolic studies, tracer experiments, and investigations in enzymatic activity related to cellular metabolism.
