Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Chinenol A is an antibacterial agent derived from the aerial parts of Helwingia chinensis. It exhibits significant activity against various bacterial strains, including Staphylococcus aureus, Mycobacterium tuberculosis, and Streptococcus pneumoniae. This compound is valuable for research focused on bacterial infections and developing therapeutic strategies against resistant bacterial pathogens. -
Antibacterial Agent
Apigravin is a potent antibacterial agent primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity against Bacillus subtilis, with a minimum inhibitory concentration (MIC) of 61 μM. This compound is valuable for research applications focused on studying bacterial infections and evaluating potential therapeutic agents against multidrug-resistant strains. -
Macrolide Compound
Sch725674 is a macrolide compound known for its antimicrobial properties, particularly against brewer's yeast and Candida albicans. The compound exhibits minimum inhibitory concentrations (MICs) of 8 μg/ml and 32 μg/ml, respectively. Its biological activity makes it suitable for research applications focused on antifungal mechanisms and the development of new antimicrobial strategies. -
Antibacterial
UCM53 is a potent FtsZ inhibitor with significant antibacterial properties. It effectively inhibits the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis. This compound is suitable for research applications involving studies on bacterial cell division and the development of novel antibacterial agents. -
Bacterial Inhibitor
Acorafloxacin hydrochloride is a broad-spectrum fluoroquinolone antibacterial agent that targets bacterial DNA gyrase and topoisomerase IV. It exhibits potent activity against a range of Gram-positive bacteria, with a mean MIC90 value of 0.12 mg/L. This compound is particularly relevant for research on acute bacterial skin infections and community-acquired pneumonia, as well as the investigation of methicillin-resistant Staphylococcus aureus (MRSA) infections. -
Anti-Bacterial Agent
Norchelerythrine is an alkaloid derived from the roots of Zanthoxylum capense, exhibiting significant antibacterial properties. It demonstrates inhibitory activity against a range of bacteria, including Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis, and Escherichia coli, with MIC values exceeding 50 µg/mL. This compound is valuable for research applications focused on evaluating antibacterial mechanisms and developing new therapeutic agents against bacterial infections. -
Antibacterial Agent
Nervogenic acid is an aromatic compound with demonstrated antibacterial properties, isolated from Piper elongatum VAHL. It exhibits significant antibacterial activity, making it a valuable reagent for research in microbiology and the development of antimicrobial therapies. Additionally, nervogenic acid offers antioxidative effects, suggesting its potential applications in studies related to oxidative stress and cellular health. -
Bacterial Inhibitor
Targeting the bacterial sliding clamp peptide 46 is a short peptide designed to inhibit the bacterial sliding clamp (SC). By interfering with SC-dependent DNA synthesis, this peptide serves as a valuable tool for studying bacterial replication mechanisms and developing novel antibacterial strategies. Its application in research underscores its potential utility in exploring bacterial growth and resistance pathways. -
Quinolone Broad-Spectrum Antibacterial Agent
PD 140248 hydrochloride is a quinolone broad-spectrum antibacterial agent that exhibits potent bacteriostatic activity, particularly against Gram-positive bacteria. This compound is valuable for in vitro studies aimed at investigating bacterial susceptibility and the mechanisms of antibacterial resistance. Its efficacy in inhibiting Gram-positive pathogens makes it a useful tool for microbiological research and antibiotic development efforts. -
Antibacterial Agent
Antibacterial agent 97 is a potent antibacterial compound with a primary mechanism of inhibiting bacterial growth. It demonstrates significant antibacterial activity, exhibiting minimum inhibitory concentrations (MIC) of 16 µg/mL against both Escherichia coli and Staphylococcus aureus. This compound is applicable in various research settings focused on understanding bacterial resistance and evaluating new antibacterial therapies. -
Bacterial Metabolite
Herbimycin C is a bacterial metabolite derived from Streptomyces hygroscopicus. It exhibits significant cytotoxicity against HeLa and Ehrlich cells, with IC50 values of 7.3 µg/mL and 1.2 µg/mL, respectively. This compound is primarily utilized in cancer research to investigate its potential therapeutic applications and mechanisms of action against tumor cells. -
Antibacterial
Ocotillone (24S)-20,24-Epoxy-25-hydroxydammaran-3-one) is a triterpenoid compound derived from the fruits of Dysoxylum richii. This compound exhibits significant antibacterial activity against pathogens such as Pseudomonas aeruginosa and Salmonella typhimurium, while demonstrating no hemolytic activity. Ocotillone is valuable for research applications focused on antibacterial drug development and the exploration of natural antimicrobial agents. -
Bacterial Growth Substrate
Di-aspartic acid (Aspartylaspartate) serves as a growth substrate for several bacterial species, including Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens, and Fusobacterium nucleatum. Its ability to support the growth of these bacteria makes it a valuable tool in microbiological research, particularly in studies related to periodontal disease and oral microbiome dynamics. -
β-lactamase Inhibitor
Pralurbactam is a potent β-lactamase inhibitor that enhances the antibacterial efficacy of Imipenem against Mycobacterium abscessus. Its ability to reduce pulmonary bacterial load in neutropenic mice highlights its potential as a significant therapeutic agent. This compound is valuable in research focused on infections caused by Mycobacterium abscessus complex, as well as strains of Escherichia coli and Klebsiella pneumoniae. -
Antibacterial Agent
Antibacterial Agent 34 is a potent antibacterial compound that enhances the efficacy of Ceftazidime by significantly reducing its minimum inhibitory concentration (MIC) value. This compound exhibits broad-spectrum antibacterial activity and serves as a valuable tool in research applications focused on overcoming antibiotic resistance and improving antibacterial therapies. Its mechanism of action may provide insights into the synergistic effects of antibiotic combinations in combating infectious diseases. -
Antibacterial
Camaric acid is a natural compound with notable antibacterial activity, isolated from the root of Lantana montevidensis. It demonstrates potential in inhibiting bacterial growth, making it a valuable reagent for research into antimicrobial agents and the development of therapeutic alternatives to conventional antibiotics. This compound can be utilized in various biological assays aimed at exploring its effects on bacterial pathogens. -
Antibacterial Agent
Asperglaucin A is a phthalide-like derivative known for its antibacterial activity. It demonstrates potent efficacy against plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with a minimum inhibitory concentration (MIC) of 6.25 μM. This compound is useful in research applications aimed at understanding antibacterial mechanisms and developing novel antimicrobial strategies. -
Bacterial
L-leucyldoxorubicin (Leurubicin) is a potent topoisomerase II inhibitor targeting bacterial cells. This compound exhibits significant antibacterial activity, making it a valuable tool for investigating bacterial infections and developing novel therapeutic strategies. Researchers can leverage its mechanism of action to explore the role of DNA topology in bacterial resistance and susceptibility. -
Antibacterial Agent
Glicophenone is an antibacterial agent that exhibits activity against various strains of Staphylococcus aureus, including MRSA and MSSA, with minimum inhibitory concentrations (MICs) of 32 μg/mL. This compound is useful in research applications focused on combating multidrug-resistant bacterial infections. Its efficacy against both methicillin-resistant and methicillin-sensitive strains makes it a valuable tool for studying bacterial resistance mechanisms. -
Antibacterial Peptide
Eumenitin is an antibacterial peptide targeting bacterial membranes, exhibiting broad-spectrum activity against both Gram-positive and Gram-negative bacteria with minimal hemolytic toxicity. It effectively induces the release of β-hexosaminidase from rat peritoneal mast cells and RBL-2H3 cells. Eumenitin is valuable for research into infectious diseases and the mechanisms of antibacterial action. -
Antibacterial Agent
Isovalerylspiramycin II is an antibacterial agent that exhibits potent activity against a variety of bacterial strains. As a primary component of the multi-component antibiotic Bitespiramycin, it plays a critical role in the study of bacterial infections. This reagent is useful in research applications aimed at understanding antibacterial mechanisms and developing new therapeutic strategies. -
Antibacterial Peptide
Oncocin is an antibacterial peptide belonging to the proline-rich antimicrobial peptide (PrAMP) class. It exhibits potent activity against Gram-negative bacteria, with minimal inhibitory concentrations (MIC) ranging from 0.125 to 8 μg/mL against various strains and clinical isolates of Enterobacteriaceae and non-fermenters. Oncocin targets the substrate-binding domain of the chaperone DnaK, leading to protein misfolding and aggregation, ultimately resulting in bacterial cell death. This mechanism makes Oncocin valuable for research into bacterial resistance and antimicrobial therapies. -
Antibacterial Drug
Xibornol is an antibacterial agent that exhibits potent activity against Gram-positive bacteria, including Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, as well as Actinomyces israelii and Corynebacterium ulcerans. This compound is especially relevant for applications in oral antisepsis and as an adjunctive treatment for pharyngeal infections caused by these microorganisms. Its effectiveness in targeting harmful bacterial strains makes Xibornol a valuable resource in antibacterial research and therapeutic development. -
Antibacterial Agents
(E)-3,4-Dimethoxychalcone acts as an antibacterial agent through its interaction with microbial cellular mechanisms. This compound exhibits significant antimicrobial and antioxidant properties, making it valuable in research applications focused on infection control and oxidative stress studies. Its isoform status enhances the understanding of structure-activity relationships in antimicrobial development. -
Bacterial Inhibitor
Cephabacin M6 is a 7-methoxydesacetylcephalosporin that acts as a bacterial inhibitor. It is isolated from the culture filtrate of Xanthomonas lactamica and exhibits significant antibacterial activity against various bacterial strains. This compound is useful in microbiological research for studying antibiotic mechanisms and resistance patterns in bacteria. -
Bacterial Inhibitor
Lascufloxacin hydrochloride is a potent antibacterial compound that targets bacterial DNA gyrase and topoisomerase IV, exhibiting broad-spectrum activity against diverse clinical isolates. It demonstrates robust efficacy against Gram-positive bacteria, outperforming other quinolone derivatives. Notably, Lascufloxacin hydrochloride shows incomplete cross-resistance to certain quinolone-resistant strains, making it a valuable candidate for further investigation. Its ability to inhibit both wild-type and mutated target enzymes underscores its potential in tackling resistant bacterial infections in research settings. -
Antibacterial Agent
EDP-420 is an orally active antibacterial agent that targets the Mycobacterium avium complex (MAC) within macrophages. It effectively reduces bacterial counts in animal models of macrolide infection and inhibits pneumococcal activity in rabbit models of meningitis. EDP-420 is suitable for research on inflammatory infectious diseases, particularly meningitis, contributing to the understanding of antibacterial strategies. -
Antibacterial Agent
Fusidic acid prodrug functions as an antibacterial agent with potent activity against Pseudomonas aeruginosa, exhibiting a minimum inhibitory concentration (MIC) of 4 µg/mL. This prodrug form enhances the efficacy of fusidic acid, making it a valuable tool for researchers studying infectious diseases and antibiotic resistance mechanisms. Its application in laboratory studies may provide insights into therapeutic strategies targeting resistant bacterial strains. -
Bacterial Inhibitor
Antibacterial Agent 63 is a conjugate of aztreonam and a siderophore mimetic, designed to inhibit gram-negative bacteria. This compound exhibits a significant antibacterial activity by targeting bacterial cell wall synthesis, providing a mechanism that enhances its effectiveness against resistant strains. It is suitable for research applications aimed at studying bacterial infections and antibiotic resistance mechanisms. -
Clarithromycin Metabolite
14-Hydroxyclarithromycin, a significant metabolite of Clarithromycin, demonstrates oral bioactivity. This compound enhances the antimicrobial effectiveness of Clarithromycin against Haemophilus influenzae in both in vitro and in vivo settings. It serves as a valuable tool in infection research, contributing to a deeper understanding of antibiotic modulation and efficacy. -
Antibacterial/Antitumoral Peptide
Dermaseptin-B3 is an antibacterial and antitumoral peptide that exhibits potent activity against both Gram-positive and Gram-negative bacteria, with minimum inhibitory concentrations (MIC) of 1.3 μM for Staphylococcus aureus, 2.3 μM for Pseudomonas aeruginosa, and varying concentrations for Escherichia coli strains (ATCC 25922: 5.0 μM; 54127: 2.6 μM). Additionally, Dermaseptin-B3 demonstrates the capability to inhibit tumor cell proliferation, making it a valuable reagent for research in antimicrobial and cancer studies. -
Bacterial Inhibitor
DA-7867 is an antibacterial compound that targets a broad spectrum of bacterial strains, including those that are drug-resistant. This amide analog of Tedizolid demonstrates significant antibacterial activity against key clinically relevant pathogens, highlighting the potential of tetrazoles in the discovery of novel antibacterial agents. Its efficacy makes DA-7867 a valuable tool for research into bacterial infections and antibiotic resistance. -
Antibacterial Agent
Antibacterial Agent 114 is a potent antibacterial compound with a primary mechanism of disrupting bacterial cell function. It exhibits significant antibacterial activity against a range of microorganisms, including Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, Enterococcus faecalis, Salmonella typhimurium, Streptococcus mutans, and Staphylococcus aureus, with MIC values of 625 μM for most and 1250 μM for specific strains. This compound is suitable for various microbiological research applications, including studies on bacterial resistance and the development of new antimicrobial therapies. -
Antibacterial agent
Clorofene (2-Benzyl-4-chlorophenol) is an aryl halide with significant antibacterial activity. It serves as a broad-spectrum disinfectant, commonly utilized in cleaning and disinfection solutions, as well as in soap formulations. Despite its effectiveness, Clorofene is recognized for its potential carcinogenic properties, warranting cautious application in research involving antibacterial agents. -
Antibacterial Agent
Sapienic acid is a fatty acid with antibacterial properties primarily targeting various Gram-positive and Gram-negative bacteria. It exhibits significant antimicrobial activity against skin and oral cavity pathogens, including Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum, with minimum bactericidal concentration (MBC) values of 31.3 μg/mL, 375.0 μg/mL, and 93.8 μg/mL, respectively. This compound is particularly useful in research applications focused on skin microbiome dynamics and oral health. -
Antibacterial Agent
Antibacterial Agent 68 is an effective antibacterial compound targeting drug-resistant Escherichia coli. This agent demonstrates potent antibacterial activity against multidrug-resistant strains at low concentrations, with an effective dose as low as 0.007 mM. Its low cytotoxicity makes it a valuable tool for researching novel treatments for bacterial infections, particularly in the context of rising antibiotic resistance. -
Antibacterial Agent
Antibacterial Agent 41 is an antibacterial compound targeting bacterial growth and survival. It demonstrates significant antimicrobial activity and is primarily utilized in research focused on developing new antibacterial therapies. Its effective mechanism makes it a valuable tool for exploring novel treatments against resistant bacterial strains. -
Bacterial Inhibitor
Ro 24-6392 is an ester-linked co-drug that combines Ciprofloxacin and Desacetylcefotaxime, targeting inhibition of bacterial growth. It demonstrates potent antibacterial activity against a range of aerobic bacteria in vitro, making it a valuable tool for microbiological research and studies focused on bacterial resistance mechanisms. This compound can be utilized in the development of novel antibacterial therapies and for evaluating bacterial susceptibility to co-drug formulations. -
Antibacterial Peptide
RT2 is a tryptophan-rich cationic amphipathic antibacterial peptide that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. It binds to LPS and interacts with cytoplasmic membrane phospholipids, which facilitates rapid penetration of the bacterial cell membrane. Once inside, RT2 binds to cytoplasmic components, including DNA, to exert potent antibacterial activity. This peptide shows promise for research into acute and chronic infections caused by planktonic bacteria. -
Bacterial Inhibitor
Apalcillin is a bacterial inhibitor designed to target and disrupt the activity of various gram-negative bacteria, particularly those that produce β-lactamase. In combination with Ro 48-1220, a β-lactamase inhibitor, Apalcillin exhibits broad-spectrum activity, effectively inhibiting strains such as Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with minimum inhibitory concentrations as low as 11 μg/mL. This combination also shows significant effectiveness against Pseudomonas aeruginosa and Stenotrophomonas maltophilia at even lower MICs (0.25 to 4 μg/mL). However, its efficacy against certain gram-positive organisms remains limited, making it a valuable tool for research on β-lactamase resistance. -
Antimicrobial
17-Hydroxyventuricidin A is an antimicrobial agent known for its inhibitory effects on specific filamentous fungi, including Verticillium dahliae and Fusarium spp., as well as the Candida tropicalis strain R2 CIP203. This compound demonstrates significant antifungal activity, making it a valuable tool for research in mycology and antifungal compound development. Its mechanism of action and efficacy position it as a potential candidate for further studies in combatting fungal infections. -
Antibacterial Agent
HC2210 is an antibacterial agent that targets Mycobacterium abscessus (Mab), demonstrating an EC50 of 0.72 µM. This compound modulates the expression of Mab genes associated with oxidative stress and lipid metabolism. HC2210 is useful for investigations into Mab infections, contributing to the understanding of bacterial resistance mechanisms and potential therapeutic strategies. -
Antimicrobial Agent
Cleroindicin F, also known as (-)-Rengyolone, is a potent antimicrobial agent. It exhibits significant anticandidal activity against various strains of Candida, demonstrating a minimum inhibitory concentration (MIC) as low as 12.5 µg/mL. This compound is valuable for research applications focused on antifungal therapeutics and microbial resistance studies. -
Bacterial Inhibitor
Phenyl(9H-purin-6-yl)amine is an antibacterial compound that targets bacterial growth by inhibiting various cellular processes. This reagent exhibits significant antibacterial activity and is useful in the development of novel antibacterial agents. Its potential inhibitory effects make it a valuable tool for medical research focused on combating bacterial infections. -
Antibacterial Drug
Multicaulisin is a Diels-Alder type adduct derived from the roots of Morus multicaulis, targeting antibacterial activity. It exhibits potent efficacy against Staphylococcus aureus, including MRSA isolates, highlighting its potential application in research focused on combating MRSA infections. This compound serves as a valuable tool for investigating new antibacterial therapies. -
Bacterial Inhibitor
Radicinol is a bacterial inhibitor derived from the metabolite of Cochliobolus lunata. It demonstrates potent antimicrobial activity, particularly against various strains of bacteria, making it a valuable tool for research in microbiology and drug development. Radicinol can be utilized to study bacterial resistance mechanisms and assess the efficacy of new antibacterial agents. -
Bacterial Inhibitor
Trimethylsilyl-L-(+)-rhamnose acts as a bacterial inhibitor through its structural similarity to natural rhamnose, playing a crucial role in the study of bacterial cell wall composition. This modified sugar is utilized to investigate the biological functions associated with bacterial growth, providing insights into mechanisms of resistance. Researchers can leverage Trimethylsilyl-L-(+)-rhamnose to enhance understanding of bacterial physiology and the implications for antibiotic development. -
Antibacterial Peptide
Penta lysine is an antibacterial peptide that effectively targets multiple bacterial strains including E. coli, A. baumannii, P. aeruginosa, S. aureus, and B. subtilis. Its minimum inhibitory concentration (MIC) ranges from 1.1 to 18 μM, demonstrating significant antimicrobial activity. Penta lysine is valuable for research applications focused on developing new antibacterial therapies and understanding microbial resistance mechanisms. -
Bacterial Inhibitor
Urechistachykinin II is a tachykinin-related peptide (TRP) derived from echiuroid worms, primarily targeting bacterial pathogens. This compound exhibits significant antimicrobial activity while demonstrating a lack of hemolytic effect, making it a valuable tool in the study of bacterial inhibition. Its unique properties may support research in microbial resistance and novel antimicrobial strategies. -
Bacterial Inhibitor
1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine (21:0 PC) functions as a surfactant with notable antibacterial properties. It exhibits efficacy by acting in mucus to inhibit the dissemination of pathogens. Additionally, 1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine contributes to the stability of biofilms, supporting the overall health of associated organisms. This compound is applicable in studies focused on bacterial inhibition and biofilm dynamics.
