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EDP-420

Catalog No.: A48948
Antibacterial Agent
EDP-420 is an orally active antibacterial agent that targets the Mycobacterium avium complex (MAC) within macrophages. It effectively reduces bacterial counts in animal models of macrolide infection and inhibits pneumococcal activity in rabbit models of meningitis. EDP-420 is suitable for research on inflammatory infectious diseases, particularly meningitis, contributing to the understanding of antibacterial strategies.
EDP-420 736992-12-4 Antibacterial Agent
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEDP-420 is an orally active antibacterial agent that targets the Mycobacterium avium complex (MAC) within macrophages. It effectively reduces bacterial counts in animal models of macrolide infection and inhibits pneumococcal activity in rabbit models of meningitis. EDP-420 is suitable for research on inflammatory infectious diseases, particularly meningitis, contributing to the understanding of antibacterial strategies.
Product Information
Catalog NumA48948
FormulaC43H64N6O11
Molecular Weight841.00
CAS Number736992-12-4
SMILESC[C@]12[C@@H]([C@H](C([C@H](C(O[C@@H]([C@@](O)([C@@](OC/C(CO2)=N\OCC3=CN=C(N4C=CC=N4)C=C3)([H])[C@H](/C([C@@H](C1)C)=N/C(C)=O)C)C)CC)=O)C)=O)C)O[C@H]5[C@@H]([C@H](C[C@H](O5)C)N(C)C)O
SynonymsEP-013420; S-013420
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Microbiology > Antifection > Bacterial