Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
8-Hydroxyerythromycin A is a semi-synthetic antibiotic primarily targeting bacterial infections. This compound exhibits significant antibacterial activity, making it valuable in the study of mechanisms of antibiotic resistance and in the development of new therapeutic strategies. It is applicable in various research fields, including microbiology and pharmacology, where understanding antibiotic efficacy is essential. -
Antibiotic
Ibafloxacine is a fluoroquinolone antibiotic designed primarily for veterinary applications. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, leading to the disruption of DNA replication and transcription in susceptible organisms. Its key biological activity includes effective treatment against various bacterial infections in animals, making it a valuable tool for veterinary medicine research and development. -
β-lactamase Antibiotic
Tigemonam is a monobactam antibiotic that targets β-lactamase enzymes, demonstrating a Ki of 0.86 μM against Enterobacter cloacae P99 and 50.8 μM against Escherichia coli TEM-1. It binds to penicillin-binding proteins 1a, 3, and 4, effectively inhibiting bacterial cell wall synthesis and exhibiting bactericidal activity against a range of aerobic gram-negative bacteria, including Enterobacteriaceae, Haemophilus influenzae, and Neisseria gonorrhoeae. Tigemonam is resistant to hydrolysis by multiple β-lactamases and has been shown to reduce bacterial load in systemic and localized infections in rodent models. This compound is valuable for research into gram-negative bacterial infections, particularly acute pyelonephritis, lung infections, and thigh muscle infections. -
Antibiotic
Tauroxicum is an antibiotic substitute that functions as a non-toxic, non-antimicrobial agent. It has been shown to enhance the health, productivity, feed efficiency, and weight gain of livestock animals. This reagent serves as a valuable tool in animal husbandry, offering a means to support livestock welfare while potentially reducing reliance on traditional antibiotics. -
Antibacterial Agent
Lysozyme from chicken egg white is an antibacterial enzyme that primarily targets and lyses gram-positive bacteria. Its bactericidal activity makes it useful in various research applications, including studies on HIV infection and the mechanisms underlying pulmonary emphysema. This enzyme plays a significant role in investigating bacterial pathogenesis and serves as a model for understanding immune responses. -
β-lactamase Inhibitor
Taniborbactam hydrochloride is a reversible and selective β-lactamase inhibitor that targets various β-lactamase enzymes, demonstrating IC50 values ranging from 8 to 530 nM, with specific IC50s of 30 nM for KPC-2, 32 nM for AmpC, 42 nM for OXA-48, and 20 nM for VIM-2. This compound is effective against Gram-negative bacteria, making it a valuable tool in the study of antibiotic resistance mechanisms and the development of novel antibacterial strategies. Researchers can utilize Taniborbactam hydrochloride in investigations aimed at enhancing the efficacy of β-lactam antibiotics. -
Bacterial Inhibitor
(Z)-Ligustilide acts as a bacterial inhibitor with demonstrated antimicrobial and antifungal properties. Extracted from Ligusticum chuanxiong Hort, it has shown an average antifungal score of 5.6. This compound inhibits the expression of FATP5 and DGAT, thereby reducing fatty acid uptake and esterification, positioning it as a potential therapeutic agent for nonalcoholic fatty liver disease (NAFLD). Additionally, (Z)-Ligustilide is involved in reactivating ERα and exhibits epigenetic regulatory functions, making it relevant for research into tamoxifen-resistant breast cancer. -
Antibacterial agent
S-Methyl thiomethanesulfonate (MMTS) is a sulfur-containing compound recognized for its antibacterial properties. It exerts its biological activity through the inhibition of microbial growth, making it valuable for studies focused on bacterial infections and plant-pathogen interactions. MMTS serves as a key reagent in research involving antimicrobial screening and the development of new antibacterial agents. -
LAL Inhibitor
Lalistat 1 is a selective and competitive inhibitor of lysosomal acid lipase (LAL), demonstrating an IC50 of 68 nM against purified human LAL. It also inhibits immunoglobulin A1 protease (IgA1P) from Haemophilus influenzae while exhibiting minimal effects on other serine hydrolases such as trypsin and β-lactamase. This compound is valuable for investigating Niemann-Pick type C (NPC) disease and related metabolic disorders. -
Beta-lactamase Inhibitor
Xeruborbactam disodium is a potent beta-lactamase inhibitor that targets both serine and metallo beta-lactamases with exceptional efficacy. This ultra-broad-spectrum compound operates at nanomolar concentrations, rendering it a valuable tool in combating antibiotic resistance. It is suitable for research applications aimed at understanding beta-lactamase mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Isoforsythiaside is a phenylethanoid glycoside known for its antioxidant and antibacterial properties. It exhibits minimum inhibitory concentrations (MICs) of 40.83 μg/mL against Escherichia coli and Pseudomonas aeruginosa, and 81.66 μg/mL against Staphylococcus aureus. This compound is useful in research applications focusing on antibacterial agents and may offer insights into microbial resistance mechanisms. -
Antibacterial Agent
Adamantane-carboxylic acid is an antibacterial agent that demonstrates inhibitory activity against various microorganisms, including both Gram-positive and select Gram-negative bacteria. This compound operates by altering the permeability of the bacterial cell membrane and can form a 1-monoacylglycerol derivative through a direct reaction with glycidol. It serves as a valuable reagent in research aimed at developing antibacterial agents, particularly in the food and cosmetic industries, to mitigate harmful microbial flora and enhance product shelf life. -
Bacterial Inhibitor
Roseoflavin is a bacterial inhibitor, functioning as an antimetabolite analog of riboflavin and flavin mononucleotide. This natural pigment, originally extracted from Streptomyces davawensis, exhibits potent antimicrobial properties. It is commonly utilized in research applications aimed at studying bacterial metabolism and the mechanisms of antibiotic resistance. -
Antibacterial Agent
D-Cysteine is the D-isomer of cysteine, known for its antibacterial properties. It exhibits inhibitory activity against key pathogens such as Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. Additionally, D-Cysteine plays a regulatory role in the proliferation of neural progenitor cells, making it valuable in various research applications focused on antibacterial mechanisms and neurobiology. The no-observed-adverse-effect level in rat studies is reported to be less than 500 mg/kg/day. -
Bacterial Inhibitor
Poly-L-lysine hydrochloride is a cationic polymer that functions as a bacterial inhibitor by enhancing cell adhesion through electrostatic interactions with negatively charged cell membranes. It promotes liquid-liquid phase separation (LLPS) at low concentrations while inhibiting LLPS at elevated concentrations, making it a versatile tool for cell culture applications. This reagent is particularly useful in studies involving bacterial attachment mechanisms and cell substrate interactions. -
Antibacterial Agent
Ceftaroline is an N-phosphono-type cephalosporin with potent antibacterial properties. It exhibits activity against a broad spectrum of gram-positive and gram-negative bacteria, making it a valuable agent for research in microbial susceptibility and resistance. Ceftaroline is primarily utilized in studies aimed at developing new therapeutic strategies to combat bacterial infections. -
Bacterial Riboflavin Riboswitches Inhibitor
Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches, targeting their regulatory mechanism to disrupt riboflavin biosynthesis. This compound exhibits a high degree of selectivity and is valuable for studying riboswitch function and its role in bacterial gene regulation. Ribocil-C is applicable in research focusing on microbial metabolism and the development of antibacterial strategies. -
Antibacterial Agent
Temocillin disodium is a 6-α-methoxy penicillin that functions as an antibacterial agent. It exhibits activity against a range of gram-negative bacteria, making it valuable in research focused on infectious diseases and antibiotic resistance. Temocillin disodium can be utilized in studies involving microbial susceptibility and therapeutic interventions for bacterial infections. -
Bacterial Collagenase Substrate
FA-Leu-Gly-Pro-Ala-OH is a furylacryloyl-terminal tetrapeptide that acts as a substrate specifically for bacterial collagenase and spirochete metalloendopeptidase. It is selectively hydrolyzed at the Leu-Gly bond by spirochete collagenase, making it useful for studying peptide bond hydrolysis kinetics. This reagent can also be employed in detecting collagenase-mediated cleavage reactions using turbidimetry through absorbance reduction, providing valuable insights into enzyme activity and specificity. -
Antibacterial agent
2-Hydroxycinnamic acid functions primarily as an antibacterial agent, exhibiting potent antimicrobial properties. This phenolic acid demonstrates efficacy against Staphylococcus aureus and remains unaffected by common drug resistance mechanisms. Additionally, it has shown inhibitory effects on HIV/SARS-CoV S pseudovirus, with an IC50 of 0.3 mM. Furthermore, 2-Hydroxycinnamic acid also possesses neuroprotective and antitumor activities, making it valuable for a variety of research applications in microbiology and oncology. -
Antibacterial Agent
MRL-494 hydrochloride is an antibacterial agent that functions as an inhibitor of the β-barrel assembly machine A (BamA), effectively circumventing efflux and the outer membrane permeability barrier. It exhibits significant antibacterial activity against Gram-positive bacteria, with a minimum inhibitory concentration (MIC) of 12.5 μM for Staphylococcus aureus COL, and against Gram-negative bacteria, with an MIC of 25 μM for Escherichia coli JCM158. This compound is suitable for research applications focused on combating bacterial infections and studying membrane protein assembly. -
Antibacterial Agents
Polyaniline is a conductive polymer primarily known for its ability to act as an antibacterial agent. Its unique electrical properties and structure enhance its interaction with microbial cells, leading to effective inhibition of growth. This compound is particularly useful in the development of antimicrobial coatings and materials for biomedical applications, making it an important resource for research in infection control and materials science. -
Antibacterial Agent
4aα,7α,7aα-Nepetalactone is an antibacterial agent that demonstrates activity against a range of pathogenic bacteria. It effectively inhibits the growth of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi, and Enterococcus faecalis. This compound is valuable for research applications focused on the study of antibacterial mechanisms and the development of new antimicrobial therapies. -
Bacterial Inhibitor
Lymecycline is a tetracycline derivative known for its mechanism as a bacterial inhibitor. It exhibits broad-spectrum antibacterial activity, making it effective against a variety of bacterial infections. Additionally, Lymecycline possesses anti-inflammatory properties, which may be beneficial in treating conditions where inflammation plays a significant role. Its applications in research include studying bacterial resistance mechanisms and exploring its therapeutic potential in inflammatory diseases. -
Bacterial Inhibitor
Procyanidin A2 is a flavonoid with documented antibacterial properties. It exhibits significant antimicrobial activity, making it a valuable compound for research into bacterial inhibition and potential therapeutic applications. Additionally, Procyanidin A2 possesses antioxidant and anti-inflammatory effects, further supporting its relevance in studies focused on cancer and inflammatory diseases. -
Bacterial Inhibitor
Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis that primarily targets bacterial pathogens. It exhibits significant anti-inflammatory and antimicrobial properties, demonstrating potent efficacy against Mycobacterium aurum and Mycobacterium bovis BCG. This compound is valuable for research focused on osteoclast differentiation, survival, and function as well as the development of novel antibacterial therapies. -
Antibacterial Agent
Sapienic acid sodium is a sodium salt of a naturally occurring fatty acid that exhibits antibacterial properties. It demonstrates variable antimicrobial activity against both Gram-positive and Gram-negative bacteria, particularly those associated with skin and oral mucosa. Notably, it is effective against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum, with minimum bactericidal concentration (MBC) values of 31.3 μg/mL, 375.0 μg/mL, and 93.8 μg/mL, respectively. This reagent is valuable for research applications focused on bacterial infections and skin health. -
Bacterial Inhibitor
Acetylalkannin is an isohexenylnaphthazarin pigment derived from Arnebia euchroma, primarily known for its bacterial inhibitory properties. This compound exhibits significant antimicrobial and cytotoxic activities, making it valuable for research in antibacterial drug development and cell viability studies. Its unique structure and biological efficacy provide a useful tool for investigating microbial interactions and potential therapeutic applications. -
Serine β-Lactamase Inhibitor
Pilabactam sodium is a potent serine β-lactamase inhibitor that demonstrates broad-spectrum activity, exhibiting IC50 values between 1 nM and 175 nM across various serine β-lactamase enzymes. This compound enhances the efficacy of β-lactam antibiotics against strains of Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). Pilabactam sodium is essential for research aimed at understanding and overcoming bacterial infections, particularly those caused by resistant pathogens. -
Antibacterial Agent
α-Pyridone is an antibacterial agent that functions as a versatile scaffold in biochemical research. It is utilized to synthesize a range of bioactive compounds, contributing to the development of new therapeutic agents. Its unique structural properties make it suitable for investigations aimed at understanding bacterial inhibition mechanisms and exploring novel antibacterial treatments. -
Anti-Bacterial Agent
Chalcone is a naturally occurring compound primarily recognized for its anti-bacterial activity. It acts as a precursor for the synthesis of various chalcone derivatives, which exhibit a broad range of biological and pharmacological effects, including anti-inflammatory, antioxidative, anticancer, and anti-parasitic properties. This compound serves as a valuable research tool in exploring therapeutic avenues for bacterial infections and related conditions. -
Antibacterial Peptide
Elf18 is a peptide fragment derived from the bacterial translation elongation factor Tu (EF-Tu), functioning primarily as an antibacterial agent. It is recognized by plant pattern recognition receptors, triggering an immune response that enhances plant resistance to various pathogens. This peptide is valuable for research applications focused on understanding and improving plant immune responses. -
Bacterial Inhibitor
4-Hydroxycoumarin is a versatile coumarin derivative that acts as a bacterial inhibitor. It demonstrates both electrophilic and nucleophilic properties, making it a valuable scaffold in organic synthesis. This compound exhibits significant biological activities, including anti-inflammatory, antibacterial, and anti-tumor effects, and has been utilized in research focusing on HIV protease and tyrosine kinase inhibition. Its multifaceted applications make it an important reagent in chemical and biological research. -
Bacterial Inhibitor
Furanone C-30 is a potent quorum sensing inhibitor that targets bacterial communication systems. It effectively disrupts biofilm formation in Streptococcus mutans, including its luxS mutant strain. This compound is valuable for research applications focused on bacterial pathogenesis and biofilm-related studies, providing insights into microbial interactions and potential therapeutic strategies against bacterial infections. -
SCD Inhibitor
Elemicin is a potent inhibitor of Stearoyl-CoA Desaturase 1 (SCD1), acting through metabolic activation. This compound exhibits a range of biological activities, including anti-influenza, antimicrobial, antioxidant, and antiviral effects. Its mechanism and diverse applications make Elemicin a valuable reagent for research in metabolic studies and infectious disease treatment. Caution is advised, as Elemicin and its reactive metabolite, 1′-Hydroxyelemicin, may induce hepatotoxicity. -
Antibacterial Agent
1-Hydroxyphenazine is an antibacterial agent that targets α-Amylase with an IC50 value of 3.1 μg/mL. This compound demonstrates significant anticancer and anti-inflammatory activities, effectively reducing proliferation in A549, 1321N1, and RAW264.7 cell lines. Additionally, 1-Hydroxyphenazine exhibits notable antifungal and antibacterial properties against pathogens such as Candida albicans, Aspergillus fumigatus, Escherichia coli, and Xanthomonas campestris, making it a valuable reagent for various biological research applications. -
Bacterial Inhibitor/Anti-inflammatory Agent
Cyclo(L-Pro-L-Val) is a peptide-based compound that functions as a bacterial inhibitor and anti-inflammatory agent. It exhibits antimicrobial activity against plant pathogens, such as R. fascians, and demonstrates significant inhibition of critical signaling molecules like IKKα, IKKβ, NF-κB, iNOS, and COX-2, contributing to its anti-inflammatory properties. This compound is valuable for research applications in developing biopesticides and investigating inflammation-related diseases. -
TEM-1 β-Lactamase Inhibitor
Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent inhibitor of TEM-1 β-lactamase, exhibiting a Ki value of 40.05 µM. This compound serves as a glycosidic surfactant, facilitating various biochemical applications. Its inhibitory properties make it valuable for research focused on antibiotic resistance and enzyme activity modulation. -
Antibacterial Agent
Diazaborine is an inhibitor of enoyl-acyl carrier protein (enoyl ACP) with an NAD+-dependent mechanism of action. This compound demonstrates significant antibacterial activity, exhibiting minimum inhibitory concentrations (MIC) of 25 µg/mL against Escherichia coli and 3.12 µg/mL against Klebsiella pneumoniae. Diazaborine serves as a valuable tool for research into antimicrobial resistance and the development of new antibacterial therapies. -
Antibacterial
2-Bromo-4-methylphenol is an antibacterial agent that targets bacterial cell growth. This compound exhibits significant antibacterial and antifungal activity, making it valuable for research in microbiology and infection control. Additionally, 2-Bromo-4-methylphenol serves as an important intermediate in the synthesis of various organic compounds, contributing to diverse chemical research applications. -
Antibacterial Agent
Curzerenone is a natural compound derived from the essential oil of L. pulcherrima, targeting bacterial cell function. It exhibits moderate antibacterial activity, specifically showing inhibitory effects against E. coli. This compound is suitable for research applications focused on investigating antibacterial agents and their mechanisms of action. -
Antibacterial Agent
Platinum(COD)dichloride is an antibacterial agent that demonstrates significant activity against a range of gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). This compound acts by disrupting bacterial cellular processes, making it a valuable tool for research focused on antimicrobial resistance and the development of new antibacterial therapies. Its unique properties position it as a promising candidate for further studies in infectious disease research. -
Beta-Lactamase Inhibitor
Ledaborbactam is a β-lactamase inhibitor that targets various β-lactamase enzymes, enhancing the efficacy of β-lactam antibiotics against resistant bacterial strains. This compound is instrumental in research focused on combating bacterial infections, especially those caused by multidrug-resistant organisms. Its ability to inhibit β-lactamases makes it a valuable tool for investigating and developing novel therapeutic approaches in infectious disease treatment. -
Bacterial Inhibitor
N-Acetyltyramine is a quorum-sensing inhibitor (QSI) produced by Vibrio alginolyticus M3-10. It effectively inhibits the quorum-sensing processes of Chromobacterium violaceum ATCC 12472, showing promise in modulating bacterial communication. Additionally, N-acetyltyramine has demonstrated the potential to reverse resistance in Doxorubicin-resistant leukemia P388 cells, making it a valuable tool for studying antibiotic resistance and leukemic cell sensitivity. -
Antibacterial Agent
Thermopsine is a quinolone-type alkaloid that acts as an antibacterial agent. It demonstrates low to moderate activity against Escherichia coli, making it a valuable tool for studying bacterial infections and resistance mechanisms. This compound is suitable for research applications in microbiology and pharmacology focused on developing new antibacterial therapies. -
Bacterial Inhibitor
Isoastilbin is a dihydroflavonol glycoside that acts primarily as a bacterial inhibitor. It effectively inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL and also shows inhibitory effects on tyrosinase activity. This compound demonstrates neuroprotective, antioxidant, antimicrobial, and anti-apoptotic properties, making it valuable for research applications related to Alzheimer's disease and other neurodegenerative conditions. -
Bacterial Inhibitor
G0507 is a pyrrolopyrimidinedione compound that acts as a potent inhibitor of the LolCDE ABC transporter in Gram-negative bacteria. By selectively inhibiting Escherichia coli growth, G0507 triggers the extracytoplasmic σE stress response, making it a valuable tool for studying lipoprotein trafficking. This compound serves as a chemical probe in bacterial research, offering insights into the mechanisms of antibiotic resistance and bacterial physiology. -
Bacterial
6-Bromo-L-tryptophan (6BrW) primarily functions as an amino acid analog for incorporation into recombinant proteins in bacterial systems. This unique substitution results in a noticeable blue shift in both fluorescence emission and absorption maxima, facilitating enhanced optical properties for protein characterization. 6BrW is a valuable tool in studies involving protein engineering, biophysical analysis, and the exploration of protein structure and dynamics. -
Bacterial Inhibitor
25-NBD Cholesterol is a fluorescently labeled cholesterol derivative that targets bacterial cell membranes. It significantly enhances the visualization and distinction between exogenous and endogenous cholesterol, emitting green fluorescence signals. This reagent is valuable for studies focused on lipid metabolism, membrane dynamics, and bacterial inhibition, promoting a deeper understanding of cholesterol's role in bacterial physiology. -
Antibiotic
PK150, an analogue of Sorafenib, is an antibiotic that demonstrates oral bioavailability and effective antibacterial activity against multiple pathogenic bacterial strains at submicromolar concentrations. Notably, PK150 exhibits inhibitory effects on Gram-positive bacteria, including Methicillin-sensitive Staphylococcus aureus (MSSA), Methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin intermediate Staphylococcus aureus (VISA), with minimum inhibitory concentrations (MICs) of 0.3 μM for MSSA and 0.3-1 μM for MRSA and VISA. This compound is suitable for research applications aimed at understanding bacterial resistance and developing novel antimicrobial therapies.
