Catalog No.
Product Name
Application
Product Information
Citations
-
Antibiotic
Cefonicid monosodium is a long-acting cephalosporin antibiotic that primarily targets bacterial cell wall synthesis. It possesses broad-spectrum antimicrobial activity, effectively combating a range of Gram-positive and Gram-negative bacteria. Additionally, Cefonicid acts as a noncompetitive inhibitor of class I β-lactamase, with a Ki value of 0.8 μM, making it a valuable reagent for research on bacterial infections and antibiotic resistance. -
Bacterial Glycoside Hydrolase Activator
4-Ethoxyquinazoline is a selective activator of bacterial glycoside hydrolases, demonstrating an AC50 of 3.5 mM. This compound enhances the enzymatic activity of glycoside hydrolases, supporting research focused on bacterial metabolism and cell wall remodeling. Its role in modulating enzyme activity makes it a valuable tool for studies on bacterial physiology and potential therapeutic applications. -
Bacterial Metabolite
Corynecin V is a chloramphenicol-like bacterial metabolite that targets bacterial protein synthesis. It exhibits antibacterial activity against a range of gram-positive bacteria by inhibiting peptidyl transferase activity in the ribosome. This compound is of significant interest in microbiological research and antibiotic development, providing insights into novel therapeutic strategies against antibiotic-resistant strains. -
α-glucosidase Inhibitor
CM-10-18 is a potent inhibitor of α-glucosidases I and II, demonstrating significant activity in vitro and in animal models. This compound also exhibits antiviral properties by inhibiting dengue virus (DENV) infection in cultured human cells, while effectively reducing peak viremia in mice. CM-10-18 is valuable for research applications related to glycosidase inhibition and viral pathogenesis. -
Anti-Viral Agent
IHVR-17028 is a broad-spectrum antiviral agent that primarily targets endoplasmic reticulum α-glucosidase I. It demonstrates significant antiviral activity against various viruses, including Bovine viral diarrhea virus (BVDV), Tick-borne choriomeningitis virus (TCRV), and Dengue virus (DENV), with EC50 values of 0.4 μM, 0.26 μM, and 0.3 μM, respectively. With an IC50 of 0.24 μM, it effectively inhibits ER α-glucosidase I, making it a valuable tool for research into infectious diseases. -
Fungicide
Cyazofamid is a fungicide that primarily targets the impairment of ATP production in fungal cells. It acts by inhibiting organic cation transporter 3 (OCT3) and organic anion transporter 1 (OAT1), with IC50 values of 1.54 μM and 17.3 μM, respectively. This compound is utilized in research to explore mechanisms of fungicidal activity and to develop effective strategies for managing fungal diseases in agricultural settings. -
Fungicide
Fenaminstrobin is a strobilurin fungicide that targets the cytochrome bc1 complex within the mitochondrial respiratory chain, leading to the inhibition of ATP production. This compound demonstrates significant biological activity in controlling a variety of fungal diseases, including Fusarium ear rot, downy mildew, rice blast, and pear scab. Additionally, Fenaminstrobin exhibits acute toxicity to the aquatic organism Daphnia magna, making it relevant for ecological impact studies. Its application in agricultural research focuses on crop protection and disease management in various plant systems. -
Mitochondrial Inhibitor
Fusaramin is a mitochondrial inhibitor that demonstrates potent activity against plant pathogenic fungi. It disrupts mitochondrial function, leading to the impairment of fungal growth and viability. This compound is valuable for research applications focused on plant disease management and the study of mitochondrial biology in pathogenic organisms. -
SDH Inhibitor
Inpyrfluxam is a potent inhibitor of succinate dehydrogenase (SDH), specifically targeting the ubiquinone binding pocket of the mitochondrial SDH complex subunits ViSDHB, ViSDHC, and ViSDHD. This inhibition disrupts cellular respiration, demonstrating efficacy in inhibiting conidial germination and mycelial growth of Venturia inaequalis in vitro. Inpyrfluxam is valuable for research studies focused on apple scab and related fungal pathogens. -
HIV-1 Integrase Inhibitor
GSK-1264 is an HIV-1 integrase inhibitor that targets the catalytic core and C-terminal domains of the HIV-1 integrase enzyme. By promoting the formation of an open polymer structure of integrase dimers, GSK-1264 disrupts the late stages of HIV replication and interferes with viral particle assembly. This compound is valuable for research focused on HIV infection and understanding integrase-mediated processes in the viral life cycle. -
HIV-1 Integrase Inhibitor
HIV-1 Integrase Inhibitor 8 is a selective inhibitor targeting the HIV-1 integrase enzyme. It demonstrates potent activity against viral replication by disrupting the integration of viral DNA into the host genome, which is essential for the HIV life cycle. This compound is primarily utilized in research focused on antiretroviral therapy and the development of HIV treatments, contributing to the understanding of integrase inhibition mechanisms. -
HIV-1Integrase Inhibitor
GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase, targeting the enzyme responsible for the integration of viral DNA into the host genome. This compound exhibits significant antiviral activity against HIV-1, making it a valuable tool for research applications focused on the development of novel antiretroviral therapies and the study of HIV replication mechanisms. Its unique mechanism of action may provide insights into resistance pathways and inform drug design strategies. -
HIV Integrase Inhibitor
His-Cys-Lys-Phe-Trp-Trp is an HIV integrase inhibitor, exhibiting an IC50 of 2 μM. This compound impedes the integrase enzyme's function, thereby preventing viral DNA integration into the host genome. His-Cys-Lys-Phe-Trp-Trp is valuable for research focused on HIV pathogenesis and the development of antiretroviral therapies. -
HIV-1 integrase Inhibitor
(S)-BI-1001 is a potent HIV-1 integrase inhibitor, demonstrating significant antiviral activity. It exhibits an IC50 value of 28 nM, an EC50 of 450 nM, and a Kd of 4.7 μM, indicating its efficacy in disrupting viral replication processes. This compound is valuable for research applications focused on HIV-1 pathogenesis and therapeutic development. -
HIV-1 Integrase Inhibitor
HIV-1 Integrase Inhibitor 7 is a potent inhibitor of HIV-1 integrase, exhibiting an IC50 value of 33.3 nM. This compound effectively interferes with the integration of viral DNA into the host genome, making it essential for studies focused on HIV-1 replication and treatment strategies. It serves as a valuable tool in research applications aimed at understanding HIV-1 biology and developing therapeutic interventions against HIV. -
HIV-1 Integrase Inhibitor
HIV-1 Integrase Inhibitor 11 is a potent inhibitor of HIV-1 integrase, demonstrating an IC50 of 125 μM. This compound effectively disrupts the integration of viral DNA into the host genome, thereby hindering the replication process of HIV-1. It is suitable for research applications aimed at developing antiretroviral therapies and studying the mechanisms of HIV integration and resistance. -
HIV-1 IN/RT RNase H Inhibitor
2-Hydroxyisoquinoline-1,3(2H,4H)-dione is an inhibitor of HIV-1 integrase (IN) and reverse transcriptase (RT) ribonuclease H (RNase H), demonstrating IC50 values of 6.32 µM and 5.9 µM, respectively. This compound serves as a valuable tool for studying HIV-1 replication and provides insights into the inhibition mechanisms of viral enzymes. Its biological activity and specificity make it useful for research applications focused on antiviral drug development and understanding HIV-1 pathogenesis. -
HIV Integrase Inhibitor
L-870812 is an HIV integrase inhibitor that targets the strand transfer mechanism of HIV-1 integration. This compound effectively blocks both cell-free and cell-associated HIV-1 infections, demonstrating activity against subtype C and CRFO2_AG primary isolates. L-870812 is suitable for research applications involving replication-deficient HIV-1 Ba-L (env) pseudovirus, facilitating studies aimed at understanding HIV biology and developing therapeutic strategies. -
Anti-bacterial Agent
6-Bromocoumarin is a potential anti-bacterial agent that demonstrates selective binding affinity for α and β estrogen receptors. While it does not inhibit 17β-HSD1, its unique properties make it a valuable compound for researchers studying bacterial resistance mechanisms and the role of estrogen receptors in microbial pathogenesis. 6-Bromocoumarin may provide insights into the development of novel anti-bacterial therapies targeting hormonal pathways. -
Acyltransferase Inhibitor
Amidepsine A is an acyltransferase inhibitor derived from the fungal metabolite of Humicola sp. FO-2942. This compound specifically inhibits the activity of diacylglycerol acyltransferases (DGAT), which play a crucial role in lipid metabolism. Its biological activity makes Amidepsine A a valuable reagent for research applications focused on lipid biosynthesis and metabolic regulation. -
NF-κB Inhibitor, GPx Inhibitor, HIV Replication Inhibitor
α-MSH (11-13) acetate is a selective melanocortin-1 receptor ligand that functions as an inhibitor of NF-κB, GPx activity, and HIV replication. It induces an acute elevation of intracellular calcium levels under certain costimulation or pathway inhibition conditions. This compound effectively suppresses TNF-α-induced NF-κB activation, inhibits colony formation of Staphylococcus aureus and Candida albicans, and demonstrates potential in the study of infections related to these pathogens, as well as in traumatic brain injury, corneal epithelial wounds, and inflammatory bowel disease research. -
Melanin Biosynthesis Inhibitor
Scytalol A is a selective inhibitor of dihydroxynaphthalene melanin biosynthesis in Lachnellula sp. A32-89, effectively disrupting melanin production without affecting the growth of the organism. This compound is valuable for research investigating melanin biosynthesis pathways and can be utilized in studies focused on fungal pigmentation and its applications in various biotechnological fields. -
Bacterial Peptide Lipid Substance
D-Allothreonine is the D stereoisomer of allothreonine, targeting bacterial peptide lipid substances. This compound can be specifically oxidized by D-amino acid oxidase, illustrating its unique reactivity compared to its L counterpart. D-Allothreonine plays a crucial role as a component of bacterial polysaccharides, making it valuable for studies on bacterial pathogenicity, antigenic variation, and mechanisms of drug resistance. Its specific biochemical interactions and applications in microbiological research highlight its significance in advancing understanding of bacterial behavior and treatment strategies. -
Anticancer/Antibacterial agents
Methyl 6-bromo-1H-indole-3-carboxylate is an indole derivative with notable anticancer and antibacterial properties. This compound demonstrates effective growth inhibition against Staphylococcus epidermidis, making it a valuable tool in studies of bacterial infections and tumorigenesis. Its diverse biological activities facilitate research in the fields of oncology and infectious diseases. -
E. coli Metabolite
Carboxyaminoimidazole ribotide (CAIR) is a potent E. coli metabolite that serves as a valuable tool for studying the PurE enzyme's active site. It is instrumental in investigating the de novo purine synthesis pathway in fungi, allowing researchers to elucidate metabolic processes and potential enzymatic regulation. Additionally, CAIR can aid in further understanding bacterial and fungal metabolism, contributing to broader applications in microbiology and biochemistry research. -
Bacterial Labeling
3-Azido-D-alanine hydrochloride is an azido-modified amino acid that serves as a versatile reagent for click chemistry applications, particularly in bacterial labeling. The presence of the azide group allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified substrates, making it a valuable tool in bioconjugation and chemical biology research. -
Bacterial Labeling
3-Azido-D-alanine is an azido-modified analog of D-alanine that serves as a valuable tool for bacterial labeling applications. It features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, 3-Azido-D-alanine can engage in ring strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds containing dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. This reagent is ideal for studies involving click chemistry in microbial systems. -
Succinate Dehydrogenase Inhibitor
Flubeneteram is an inhibitor of succinate dehydrogenase, exhibiting an IC50 value of 0.0484 μM. This compound effectively disrupts the activity of succinate dehydrogenase, contributing to its biological activity. Flubeneteram has demonstrated protective effects against fungal pathogens such as Rhizoctonia solani and Sphaerotheca fuliginea in preclinical studies. It is a valuable reagent for research focused on fungal infection mechanisms and potential therapeutic strategies. -
Metal Chelator
Calcium disodium edetate hydrate is a metal chelator that effectively targets and binds divalent metal ions, including manganese (Mn2+). Its biological activity includes the disruption of mitochondrial function and interference with carbohydrate metabolism, particularly in the synthesis of pyruvate during glycolysis. Additionally, Calcium disodium edetate hydrate exhibits antifungal properties by inhibiting the growth of Penicillium digitatum and delaying conidial germination. This compound is valuable for research focused on controlling citrus green mold and enhancing host defense mechanisms in citrus fruits. -
Nonionic Surfactant
Polyoxyl 40 stearate (PEG 40 stearate) functions as a nonionic surfactant, synthesized through the esterification of stearic acid with polyethylene glycol containing approximately 40 ethoxy units. It exhibits key biological activity in the formulation of pharmaceutical preparations and nanodrug carriers, facilitating emulsification and stabilization of active compounds. Applications include its use as a matrix component in solid lipid nanoparticles for the controlled release of encapsulated antifungal drugs, as well as serving as a base material for vaginal drug delivery systems, where it can be modified with acryloyl chloride to introduce polymerizable groups. -
Glucosaminide Substrate
VLPA-GlcNAc is a chromogenic glucosaminide substrate that serves as a valuable tool for the identification of Candida species. It can be utilized in the preparation of specialized agar media, facilitating the differentiation of Candida strains based on their enzymatic activity. This reagent is essential in microbiological research and diagnostics, particularly in clinical settings where rapid identification of fungal pathogens is crucial. -
Chlorinated Phenol Active Substance
4,5-Dichloroguaiacol is a chlorinated phenol active substance known for its role in various biochemical applications. It exhibits significant antibacterial and antifungal properties, making it valuable in studies focused on microbial inhibition. This compound is commonly utilized in research involving antimicrobial assays and as a standard in environmental toxicology. -
Antibacterial Agent
3,6-Diaminoacridine hydrochloride is an antibacterial agent that targets bacterial cell membranes, disrupting their integrity. This compound exhibits significant antibacterial activity, making it a valuable reagent for microbial studies and preservation applications. Its utility extends to research involving antibiotic resistance and the evaluation of antibacterial compounds. -
Chlorophenolic Compound
3,4,5-Trichlorosyringol is a chlorophenolic compound that is synthesized through the chlorination of syringol in carbon disulfide (CS2). This compound exhibits anti-fungal and anti-bacterial activities, making it useful for research involving microbial growth inhibition. It is applicable in studies focused on phytopathology, environmental microbiology, and the development of antimicrobial agents. -
Nutritional Additive
Corn steep liquor serves as a nutritional additive, primarily utilized in liquid culture media for fungal cultivation. It enhances the production of mycelial growth and secondary metabolites, supporting research in microbial metabolism and biotechnology applications. This by-product of corn processing provides essential nutrients that promote optimal fungal development and yield. -
Immune System Modulator
Zymosan (ZM), 95% is an immune system modulator derived from yeast cell walls that primarily targets TLR-2, TLR-4, and Dectin-1 receptors. It activates downstream signaling pathways that enhance TLR-2, TLR-4, and TNF-α mRNA expression, leading to increased serum TNF-α levels and improved splenocyte viability in murine models. Zymosan (ZM), 95% has been shown to inhibit melanoma growth, modulate macrophage marker gene expression, and induce pro-inflammatory factor production in human corneal cells. Additionally, it serves as a drug carrier and supports fibroblast cell attachment in hydrogel formulations, making it a valuable tool for research on melanoma, tumors, fungal keratitis, and ocular surface inflammatory disorders. -
Detection Substrate
5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside functions as a sensitive enzyme substrate with chemiluminescent properties. It facilitates the detection of various enzymatic activities, making it suitable for diagnostic assays aimed at identifying bacterial and fungal infections, as well as other diseases. Its utility in research applications enhances the reliability of assays in clinical microbiology and molecular diagnostics. -
Immunity Enhancer
Tremella polysaccharide, a high molecular weight fungal polysaccharide, functions primarily as an immunity enhancer. This compound exhibits notable biological activity by modulating immune responses, making it relevant for research applications focused on addressing leukopenia induced by chemotherapy and radiotherapy. Its cosmetic grade designation further supports its potential in skin health and immune support formulations. -
Organosulfur Compound
Thiosalicylic acid, an organosulfur compound featuring both sulfhydryl and carboxyl functional groups, primarily functions as a desulfurizing agent. This compound is utilized as a ligand in the synthesis of azosulfonamide derivatives, which exhibit antibacterial and antifungal properties. Additionally, thiosalicylic acid facilitates the formation of metal chelates, specifically with Fe3+, Cu2+, and Hg2+, enhancing its versatility in various biochemical applications. -
Pyrrole Compound
Methyl 5-bromo-1H-pyrrole-2-carboxylate is a pyrrole compound with a unique brominated structure. Its primary biological activities include various antimicrobial and antifungal properties. This reagent is useful in chemical research focused on synthesizing novel pyrrole derivatives and studying their potential applications in pharmaceuticals and biologically active compounds. -
Antifungal/Antibacterial Agent
1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol exhibiting diverse biological activities, including antifungal, antibacterial (active against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer, and antioxidant effects. It can be isolated from the leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol demonstrates significant inhibitory activity against pathogenic fungi and shows potential efficacy in controlling pepper anthracnose in phytopathological studies. This compound is a valuable research tool for investigations in fungal infections, oncology, and oxidative stress-related disorders.
-
Redox Isomer
Neopatulin is a redox isomer and a critical biogenetic precursor of the antibiotic patulin, commonly produced by various fungal species. This compound plays a significant role in studies pertaining to antibiotic synthesis and fungal metabolism. Neopatulin can be synthesized through methods such as Lewis acid-catalyzed aldol reactions or utilizing 2-formyl-1,3-dithiane in conjunction with 2-(tert-butyldimethylsiloxy)-4-[(tert-butyldimethylsiloxy)-methyl]furan, making it a valuable reagent for chemical research applications. -
Phenolic Compound
Daphneolone is a phenolic compound known for its potential antifungal properties against plant pathogenic fungi. Isolated from the roots of Daphneodora, this compound is valuable for research into natural antifungal agents and plant defense mechanisms. Its analogues may offer insights into the development of eco-friendly agricultural solutions. -
Oxylipin
8(R),11(S)-DiHODE is a fungal oxylipin that primarily targets lipid signaling pathways. It is known to play a role in modulating inflammatory responses and cell signaling processes. This compound is of particular interest in research applications related to metabolic diseases, inflammation, and fungal biology, providing insights into the biochemical pathways influenced by oxylipins. -
Anticancer Agent
Antitumor Agent-160 is a derivative of the antifungal compound phenalenone, serving as an anticancer agent. It exhibits significant antitumor activity, making it a valuable tool in cancer research. Its potential applications include the study of cancer cell proliferation and the evaluation of therapeutic strategies in oncological research. -
Stable Isotope
Loratadine-d5-1 is a deuterated analog of Loratadine, which serves as a selective inverse agonist of peripheral histamine H1 receptors. It exhibits an IC50 of greater than 32 μM and has been shown to possess anti-dengue virus (DENV) activity. Additionally, Loratadine is capable of inhibiting the immunologic release of inflammatory mediators, making it a valuable tool for research in allergy and inflammation studies. -
Antimicrobial Agent
1,2-Hexanediol serves as a broad-spectrum antimicrobial agent with significant antibacterial and antifungal properties. It exhibits bactericidal activity against both Gram-positive and Gram-negative bacteria, while also effectively inhibiting various fungal organisms. The compound disrupts the cytoplasmic membrane potential of bacteria, making it an essential tool in research focused on bacterial and fungal infections, as well as applications in cosmetic preservation. -
Fungicide
Nuarimol is a fungicide that primarily targets fungal pathogens to protect crops in agricultural applications. This compound functions as a phenobarbital-type inducer of hepatic drug-metabolizing enzymes, leading to transient, significant hepatic regenerative proliferation and accompanying hepatomegaly through reversible hepatocellular injury. Research indicates its potential utility in studies exploring liver regeneration and metabolic enzyme regulation. -
Chlorinated Phenol
Tetrachloroguaiacol is a chlorinated phenol primarily formed during the chlorine bleaching of wood pulp. It exhibits significant antibacterial and antifungal activities, making it relevant for studies in environmental science and biochemistry. This compound serves as a valuable reagent in research focused on the effects of chlorinated compounds on biological systems and their potential environmental impact. -
α,β-unsaturated Fatty Acid
2-Decenoic acid is an α,β-unsaturated fatty acid known to inhibit plant pollen germination and pollen tube elongation. This compound exhibits significant biological activity, making it a valuable tool for research in plant reproductive biology. Additionally, its antimicrobial properties suggest potential applications in developing antifungal and antibacterial agents.
