Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Cefonicid monosodium is a long-acting cephalosporin antibiotic that primarily targets bacterial cell wall synthesis. It possesses broad-spectrum antimicrobial activity, effectively combating a range of Gram-positive and Gram-negative bacteria. Additionally, Cefonicid acts as a noncompetitive inhibitor of class I β-lactamase, with a Ki value of 0.8 μM, making it a valuable reagent for research on bacterial infections and antibiotic resistance. -
Bacterial Glycoside Hydrolase Activator
4-Ethoxyquinazoline is a selective activator of bacterial glycoside hydrolases, demonstrating an AC50 of 3.5 mM. This compound enhances the enzymatic activity of glycoside hydrolases, supporting research focused on bacterial metabolism and cell wall remodeling. Its role in modulating enzyme activity makes it a valuable tool for studies on bacterial physiology and potential therapeutic applications. -
Bacterial Metabolite
Corynecin V is a chloramphenicol-like bacterial metabolite that targets bacterial protein synthesis. It exhibits antibacterial activity against a range of gram-positive bacteria by inhibiting peptidyl transferase activity in the ribosome. This compound is of significant interest in microbiological research and antibiotic development, providing insights into novel therapeutic strategies against antibiotic-resistant strains. -
Drug Derivative
Fluopicolide is a novel drug derivative with a primary mechanism targeting specific protein interactions. It exhibits significant antifungal activity, making it suitable for studying plant pathogen resistance and developing effective agricultural fungicides. Fluopicolide is particularly valuable for research applications focused on crop protection and plant disease management strategies. -
Alternaria Metabolite
4-Hydroxyalternariol is a metabolite derived from the fungus Alternaria. It exhibits significant cytotoxic activity and serves as a potent inhibitor of various cell proliferation pathways. This compound is valuable in research focused on mycotoxin studies, apoptosis, and cancer biology, facilitating investigations into the biological effects of fungal metabolites on human health. -
Metabolite
(Z)-2-Octenoic acid is the Z-isomer of 2-Octenoic acid, a significant metabolite derived from Mucor species. It plays a role in various biochemical pathways and can be utilized in studies exploring fungal metabolism and organic compound synthesis. This compound may aid in the investigation of microbial interactions and the functional roles of metabolites in ecological systems. -
Secondary Metabolite
4-Hydroxyscytalone is a microbial secondary metabolite isolated from the oak fungus Diplodia corticola. This compound exhibits toxicity toward Artemia salina with an LC50 value of 90.6 μg/mL, indicating its potential as a bioactive agent. While it does not demonstrate significant antifungal activity, 4-Hydroxyscytalone may serve as a valuable tool in cancer therapy research, facilitating investigations into novel treatment strategies. -
Squalene Synthase Inhibitor
Squalestatin 3 is a potent squalene synthase inhibitor, demonstrating an IC50 of 6 nM. This secondary metabolite, isolated from the fungus Phoma, plays a critical role in regulating the biosynthesis of sterols and terpenes. It is valuable for research applications focused on cholesterol biosynthesis, antifungal research, and the exploration of lipid metabolism pathways. -
Fungal Lactone
Pestalotin is a fungal lactone and a secondary metabolite derived from the endophytic fungus Pestalotiopsis microspora. This compound exhibits significant antifungal activity, making it a valuable tool for research in mycology and natural product chemistry. Its bioactive properties may facilitate the exploration of new antimicrobial agents and contribute to the study of plant-fungal interactions. -
Secondary Metabolite
Fumiquinazoline D is a secondary metabolite that acts as a mycotoxin. It exhibits significant biological activity by inhibiting various cellular processes, potentially impacting cell viability and proliferation. Fumiquinazoline D is utilized in research to study the effects of mycotoxins on human health and to explore its mechanisms of action in fungal biology and toxicity. -
Anticancer Agent/SV40 Promoter Activator
TMC-205 is a natural fungal metabolite that acts as an SV40 promoter activator. It exhibits significant antiproliferative activity against various cancer cell lines, making it a valuable tool for cancer research. This compound is useful for studies on transcriptional regulation and the mechanisms of oncogenesis. -
Antibiotic
Neohydroxyaspergillic acid is an antibiotic that exhibits activity against specific bacteriophages. This compound can be utilized in research focusing on antibacterial mechanisms and the interaction between antibiotics and bacteriophages. Its potential applications extend to studying resistance and susceptibility patterns in microbial populations. -
Bacterial Metabolite
Corynecin IV is a chloramphenicol-like bacterial metabolite that targets bacterial protein synthesis through inhibition of the bacterial ribosome. This compound exhibits antimicrobial activity against a range of Gram-positive bacteria, making it valuable for research in antibiotic development and resistance studies. Additionally, Corynecin IV can be utilized to explore mechanisms of action for similar anti-infective agents. -
Fungi Metabolites
Scytalone is a naphthalenone pentaketide that serves as a natural precursor to melanin. This compound is derived from certain tracheiphilous fungi and is relevant in the study of fungal metabolites. Research indicates that scytalone may play a role in grape esca disease, making it a valuable reagent for investigations into plant pathology and fungal biology. -
Ciosynthetic Precursor of Satratoxin G
Roridin L2 is a fungal metabolite that serves as a biosynthetic precursor to Satratoxin G. This compound plays a crucial role in the synthesis of Satratoxin G, which is known for its potential biological activities. Despite its significance in research applications, Roridin L2 exhibits minimal toxic activity both in vitro and in vivo, making it a valuable reagent for studying fungal metabolites and their derivatives. -
Bacterial Metabolite
4-Hydroxycinnamide is a bacterial metabolite derived from Streptomyces sp. PU-KB10-4. This compound exhibits significant biological activity, making it a valuable tool in microbial research. Its role in bacterial metabolism may provide insights into host-microbe interactions and potential therapeutic applications. -
Metabolite
Eremofortin A is a natural metabolite derived from the fungus Penicillium roqueforti. This compound exhibits a range of biological activities, including potential antifungal and cytotoxic effects. Eremofortin A is primarily utilized in research applications focused on exploring fungal metabolites and their therapeutic potentials in the treatment of various diseases. -
Acinar Morphogenesis Inhibitor
Fusarisetin A is a pentacyclic fungal metabolite that functions as an acinar morphogenesis inhibitor. This compound disrupts the normal formation and development of acinar structures in cells, making it a valuable tool for investigating the mechanisms of acinar morphogenesis. Its unique biological activity supports research in developmental biology and tissue engineering. -
C-14 Epimer
14-epi-Berkeleylactone F is a C-14 epimer of Berkeleylactone F, isolated from the fungus Penicillium turbatum NRRL 5630. While it demonstrates structural similarity to its counterpart, 14-epi-Berkeleylactone F exhibits no significant biological activity against a range of pathogens, including Staphylococcus aureus, Bacillus subtilis, E. coli, Candida albicans, and the parasite Giardia duodenalis, as well as NS-1 murine myeloma cells. This compound may be relevant for studies focusing on epimerization and structural analysis in fungal metabolites. -
Secondary Metabolite
Neosartoricin D is a polyketide and a microbial secondary metabolite isolated from the culture of Aspergillus nidulans. This compound exhibits biological activity that suggests potential immunomodulatory effects, influencing host-pathogen interactions during fungal infections. Neosartoricin D serves as a valuable research tool for studying the mechanisms of fungal pathology and its impact on host immune responses. -
Immunosuppressant
Homodestcardin is a destruxin-based cyclodepsipeptide that functions as an immunosuppressant. Derived from fungal sources, it exhibits significant inhibitory activity against concanavalin A (Con A) activation, demonstrating an IC50 value of 0.86 μM. This compound is of interest for research applications focused on immune modulation and the study of autoimmune disorders. -
Biologically Active Metabolite
Varioxepine A is a 3H-oxepine-containing alkaloid that acts as a biologically active metabolite derived from the marine algal endophytic fungus Paecilomyces variotii. This compound exhibits inhibitory activity against the plant pathogenic fungus Fusarium graminearum, making it a valuable tool for research in phytopathology and the study of plant-fungal interactions. Its unique structural features may also provide insights into the development of novel antifungal agents. -
Bacterial Peptide Lipid Substance
D-Allothreonine is the D stereoisomer of allothreonine, targeting bacterial peptide lipid substances. This compound can be specifically oxidized by D-amino acid oxidase, illustrating its unique reactivity compared to its L counterpart. D-Allothreonine plays a crucial role as a component of bacterial polysaccharides, making it valuable for studies on bacterial pathogenicity, antigenic variation, and mechanisms of drug resistance. Its specific biochemical interactions and applications in microbiological research highlight its significance in advancing understanding of bacterial behavior and treatment strategies. -
Anticancer/Antibacterial agents
Methyl 6-bromo-1H-indole-3-carboxylate is an indole derivative with notable anticancer and antibacterial properties. This compound demonstrates effective growth inhibition against Staphylococcus epidermidis, making it a valuable tool in studies of bacterial infections and tumorigenesis. Its diverse biological activities facilitate research in the fields of oncology and infectious diseases. -
E. coli Metabolite
Carboxyaminoimidazole ribotide (CAIR) is a potent E. coli metabolite that serves as a valuable tool for studying the PurE enzyme's active site. It is instrumental in investigating the de novo purine synthesis pathway in fungi, allowing researchers to elucidate metabolic processes and potential enzymatic regulation. Additionally, CAIR can aid in further understanding bacterial and fungal metabolism, contributing to broader applications in microbiology and biochemistry research. -
Succinate Dehydrogenase Inhibitor
Flubeneteram is an inhibitor of succinate dehydrogenase, exhibiting an IC50 value of 0.0484 μM. This compound effectively disrupts the activity of succinate dehydrogenase, contributing to its biological activity. Flubeneteram has demonstrated protective effects against fungal pathogens such as Rhizoctonia solani and Sphaerotheca fuliginea in preclinical studies. It is a valuable reagent for research focused on fungal infection mechanisms and potential therapeutic strategies. -
Bacterial Labeling
3-Azido-D-alanine hydrochloride is an azido-modified amino acid that serves as a versatile reagent for click chemistry applications, particularly in bacterial labeling. The presence of the azide group allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified substrates, making it a valuable tool in bioconjugation and chemical biology research. -
Bacterial Labeling
3-Azido-D-alanine is an azido-modified analog of D-alanine that serves as a valuable tool for bacterial labeling applications. It features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, 3-Azido-D-alanine can engage in ring strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds containing dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. This reagent is ideal for studies involving click chemistry in microbial systems. -
Nutritional Additive
Corn steep liquor serves as a nutritional additive, primarily utilized in liquid culture media for fungal cultivation. It enhances the production of mycelial growth and secondary metabolites, supporting research in microbial metabolism and biotechnology applications. This by-product of corn processing provides essential nutrients that promote optimal fungal development and yield. -
Immune System Modulator
Zymosan (ZM), 95% is an immune system modulator derived from yeast cell walls that primarily targets TLR-2, TLR-4, and Dectin-1 receptors. It activates downstream signaling pathways that enhance TLR-2, TLR-4, and TNF-α mRNA expression, leading to increased serum TNF-α levels and improved splenocyte viability in murine models. Zymosan (ZM), 95% has been shown to inhibit melanoma growth, modulate macrophage marker gene expression, and induce pro-inflammatory factor production in human corneal cells. Additionally, it serves as a drug carrier and supports fibroblast cell attachment in hydrogel formulations, making it a valuable tool for research on melanoma, tumors, fungal keratitis, and ocular surface inflammatory disorders. -
Immunity Enhancer
Tremella polysaccharide, a high molecular weight fungal polysaccharide, functions primarily as an immunity enhancer. This compound exhibits notable biological activity by modulating immune responses, making it relevant for research applications focused on addressing leukopenia induced by chemotherapy and radiotherapy. Its cosmetic grade designation further supports its potential in skin health and immune support formulations. -
Organosulfur Compound
Thiosalicylic acid, an organosulfur compound featuring both sulfhydryl and carboxyl functional groups, primarily functions as a desulfurizing agent. This compound is utilized as a ligand in the synthesis of azosulfonamide derivatives, which exhibit antibacterial and antifungal properties. Additionally, thiosalicylic acid facilitates the formation of metal chelates, specifically with Fe3+, Cu2+, and Hg2+, enhancing its versatility in various biochemical applications. -
Pyrrole Compound
Methyl 5-bromo-1H-pyrrole-2-carboxylate is a pyrrole compound with a unique brominated structure. Its primary biological activities include various antimicrobial and antifungal properties. This reagent is useful in chemical research focused on synthesizing novel pyrrole derivatives and studying their potential applications in pharmaceuticals and biologically active compounds. -
Antifungal/Antibacterial Agent
1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol exhibiting diverse biological activities, including antifungal, antibacterial (active against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer, and antioxidant effects. It can be isolated from the leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol demonstrates significant inhibitory activity against pathogenic fungi and shows potential efficacy in controlling pepper anthracnose in phytopathological studies. This compound is a valuable research tool for investigations in fungal infections, oncology, and oxidative stress-related disorders.
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Metal Chelator
Calcium disodium edetate hydrate is a metal chelator that effectively targets and binds divalent metal ions, including manganese (Mn2+). Its biological activity includes the disruption of mitochondrial function and interference with carbohydrate metabolism, particularly in the synthesis of pyruvate during glycolysis. Additionally, Calcium disodium edetate hydrate exhibits antifungal properties by inhibiting the growth of Penicillium digitatum and delaying conidial germination. This compound is valuable for research focused on controlling citrus green mold and enhancing host defense mechanisms in citrus fruits. -
Nonionic Surfactant
Polyoxyl 40 stearate (PEG 40 stearate) functions as a nonionic surfactant, synthesized through the esterification of stearic acid with polyethylene glycol containing approximately 40 ethoxy units. It exhibits key biological activity in the formulation of pharmaceutical preparations and nanodrug carriers, facilitating emulsification and stabilization of active compounds. Applications include its use as a matrix component in solid lipid nanoparticles for the controlled release of encapsulated antifungal drugs, as well as serving as a base material for vaginal drug delivery systems, where it can be modified with acryloyl chloride to introduce polymerizable groups. -
Glucosaminide Substrate
VLPA-GlcNAc is a chromogenic glucosaminide substrate that serves as a valuable tool for the identification of Candida species. It can be utilized in the preparation of specialized agar media, facilitating the differentiation of Candida strains based on their enzymatic activity. This reagent is essential in microbiological research and diagnostics, particularly in clinical settings where rapid identification of fungal pathogens is crucial. -
Chlorinated Phenol Active Substance
4,5-Dichloroguaiacol is a chlorinated phenol active substance known for its role in various biochemical applications. It exhibits significant antibacterial and antifungal properties, making it valuable in studies focused on microbial inhibition. This compound is commonly utilized in research involving antimicrobial assays and as a standard in environmental toxicology. -
Antibacterial Agent
3,6-Diaminoacridine hydrochloride is an antibacterial agent that targets bacterial cell membranes, disrupting their integrity. This compound exhibits significant antibacterial activity, making it a valuable reagent for microbial studies and preservation applications. Its utility extends to research involving antibiotic resistance and the evaluation of antibacterial compounds. -
Chlorophenolic Compound
3,4,5-Trichlorosyringol is a chlorophenolic compound that is synthesized through the chlorination of syringol in carbon disulfide (CS2). This compound exhibits anti-fungal and anti-bacterial activities, making it useful for research involving microbial growth inhibition. It is applicable in studies focused on phytopathology, environmental microbiology, and the development of antimicrobial agents. -
Detection Substrate
5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside functions as a sensitive enzyme substrate with chemiluminescent properties. It facilitates the detection of various enzymatic activities, making it suitable for diagnostic assays aimed at identifying bacterial and fungal infections, as well as other diseases. Its utility in research applications enhances the reliability of assays in clinical microbiology and molecular diagnostics. -
Redox Isomer
Neopatulin is a redox isomer and a critical biogenetic precursor of the antibiotic patulin, commonly produced by various fungal species. This compound plays a significant role in studies pertaining to antibiotic synthesis and fungal metabolism. Neopatulin can be synthesized through methods such as Lewis acid-catalyzed aldol reactions or utilizing 2-formyl-1,3-dithiane in conjunction with 2-(tert-butyldimethylsiloxy)-4-[(tert-butyldimethylsiloxy)-methyl]furan, making it a valuable reagent for chemical research applications. -
Phenolic Compound
Daphneolone is a phenolic compound known for its potential antifungal properties against plant pathogenic fungi. Isolated from the roots of Daphneodora, this compound is valuable for research into natural antifungal agents and plant defense mechanisms. Its analogues may offer insights into the development of eco-friendly agricultural solutions. -
Oxylipin
8(R),11(S)-DiHODE is a fungal oxylipin that primarily targets lipid signaling pathways. It is known to play a role in modulating inflammatory responses and cell signaling processes. This compound is of particular interest in research applications related to metabolic diseases, inflammation, and fungal biology, providing insights into the biochemical pathways influenced by oxylipins. -
Penicillium Intermediate
Cyclopeptine is a key intermediate in the biosynthesis of benzodiazepine alkaloids produced by the genus Penicillium. This compound is significant for research into the metabolic pathways of fungal secondary metabolites and their potential applications in pharmacology. Cyclopeptine can also be utilized to study the structural and functional properties of benzodiazepine derivatives in various biological systems. -
Secondary Metabolite of Aspergillus flavus
5,7-Dihydroxy-4-methylphthalide is a secondary metabolite produced by Aspergillus flavus, serving as a crucial intermediate in the synthesis of Mycophenolic acid. This compound exhibits significant biological activity, contributing to the understanding of fungal metabolism and the pharmacological properties of derived compounds. Its applications encompass research into fungal biosynthesis and the exploration of potential therapeutic agents stemming from fungal secondary metabolites. -
Anticancer Agent
Antitumor Agent-160 is a derivative of the antifungal compound phenalenone, serving as an anticancer agent. It exhibits significant antitumor activity, making it a valuable tool in cancer research. Its potential applications include the study of cancer cell proliferation and the evaluation of therapeutic strategies in oncological research. -
Phenolic Compound
3,4,5-Trichloroguaiacol is a phenolic compound primarily targeted for its antibacterial and antifungal properties. It is often utilized in studies examining environmental contaminants, particularly in the context of effluents from bleached kraft pulp mills. This compound serves as an important research tool in understanding the biochemical pathways influenced by chlorinated phenols and their impacts on microbial activity. -
Lanostane-type Triterpenoid Compound
Inonotusane A is a lanostane-type triterpenoid compound isolated from the sclerotia of Inonotus obliquus. This compound exhibits notable biological activity, including potential anticancer properties and immunomodulatory effects. It serves as a valuable reagent for research focused on natural products, herbal medicine, and the therapeutic potential of fungal metabolites in various biological systems. -
Terpenoid
Monardin C is a natural terpenoid known for its ability to modulate various biological pathways. It exhibits significant antibacterial and antifungal activities, making it a valuable compound in microbiological research. Monardin C's unique properties render it useful for studies focused on the therapeutic potential of terpenoids in infectious diseases and alternative medicine approaches.
