Catalog No.
Product Name
Application
Product Information
Citations
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Nucleoside Antibiotic
Psicofuranine is a nucleoside antibiotic that primarily inhibits xanthosine 5'-phosphate aminase and selectively targets GMP synthase. This compound disrupts the growth of parasites, demonstrating dose-dependent inhibitory effects on Plasmodium falciparum. Psicofuranine is a valuable tool for research applications in parasitology and antimicrobial drug development. -
Antibiotic
Cefquinome is a broad-spectrum cephem antibiotic that targets bacterial cell wall synthesis, exhibiting efficacy against a range of Gram-positive and Gram-negative bacteria. Its spectrum of activity includes important pathogens such as Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae. Cefquinome is utilized in microbiological research to study antibiotic resistance mechanisms and the effectiveness of therapeutic interventions. -
Carbapenem Antibiotic Combination
Imipenem and cilastatin sodium is a broad-spectrum carbapenem antibiotic combination effective against a wide range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem, the active antibiotic, exhibits rapid bactericidal activity, while cilastatin acts as a renal dehydropeptidase inhibitor, preventing the renal metabolism of imipenem and enhancing its urinary concentration. This combination is commonly utilized in research settings to study antibiotic efficacy and resistance mechanisms. -
Antibiotic
Valnivudine, a nucleoside analogue, exhibits antiviral activity primarily against varicella-zoster virus (VZV). It serves as a proagent to the bicyclic nucleoside analog CF-1743, demonstrating significant efficacy in the treatment of herpes zoster. Following oral administration, Valnivudine is rapidly and extensively converted to CF-1743 in vivo, enhancing its therapeutic potential in clinical applications focused on herpesvirus infections. -
Antibiotic
Sulfacytine is a short-acting sulfonamide antibiotic that exhibits antibacterial activity by inhibiting bacterial folic acid synthesis. It is primarily utilized in research focused on acute uncomplicated urinary tract infections, showcasing its effectiveness against various bacterial pathogens. This reagent is valuable for studies exploring antibiotic efficacy and mechanisms of resistance. -
Aminomethylcycline Antibiotic
Zifanocycline is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits bacterial ribosome function. It demonstrates broad-spectrum in vitro antibacterial activity against both Gram-positive and Gram-negative bacteria, including numerous multidrug-resistant strains. Zifanocycline is applicable in the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections. -
Antibiotic
3-Desacetyl Cefotaxime lactone is the active metabolite of the third-generation cephalosporin antibiotic Cefotaxime. This compound exhibits significant antibacterial activity against a broad spectrum of Gram-positive and Gram-negative bacteria. It is primarily utilized in research applications to study antibiotic efficacy, resistance mechanisms, and the pharmacokinetics of cephalosporin derivatives. -
Antibiotic
Rhodomyrtone is an antibiotic derived from the leaves of Rhodomyrtus tomentosa, specifically targeting Gram-positive bacteria. This compound exhibits bactericidal activity through a mechanism that does not induce bacteriolysis, effectively eliminating strains such as Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes, and Streptococcus salivarius. Rhodomyrtone is suitable for research applications concerning bacterial infections and antimicrobial resistance studies. -
Antibiotic
Rifamycin B is an ansamycin antibiotic that primarily targets bacterial RNA polymerase, exhibiting significant anti-mycobacterial activity against pathogens such as Mycobacterium tuberculosis, leprosy, and various AIDS-related mycobacterial infections. Derived from the natural product of Nocardia inediterranei, Rifamycin B also serves as a precursor for the formation of Rifamycin O and Rifamycin S through microbial transformation. This compound is essential for research focused on antibiotic resistance and the treatment of mycobacterial diseases. -
Antibiotic
Streptazolin is an antibiotic that enhances bacterial clearance and promotes the secretion of immunostimulatory cytokines by macrophages in vitro. It activates the macrophage NF-κB pathway through the PI3K signaling cascade, contributing to its immunomodulatory effects. This compound is valuable for research applications aimed at understanding antibiotic efficacy and macrophage behavior in immune responses. -
Antibiotic
Herbimycin A is an ansamycin antibiotic that serves as a potent inhibitor of Src family kinases. By binding to the SH domain, it effectively inhibits the activity of p60v-src and p210BCR-ABL, highlighting its relevance in cancer research. Additionally, Herbimycin A disrupts Hsp90 function and impedes cellular recovery from heat shock, while also demonstrating antiangiogenic properties in vitro in endothelial cells. This reagent is valuable for studies focusing on cellular stress responses and angiogenesis. -
Antibiotic
DL-Lanthionine is an amino acid that functions as a crucial monosulfide analog of cystine. It serves as a key component in the structure of peptide antibiotics known as lantiobiotics, which include prominent members like nisin and subtilin. DL-Lanthionine is instrumental in researching antibiotic mechanisms and developing novel antimicrobial agents with therapeutic potential. -
Antibiotic
A-54556A (ADEP 1) is an acyldepsipeptide antibiotic that primarily targets bacterial protein synthesis. It exhibits potent antibacterial activity against a diverse array of Gram-positive bacteria, making it a valuable tool for research on bacterial resistance and antibiotic efficacy. A-54556A is utilized in studies exploring mechanism of action and the development of novel antimicrobial agents. -
Antibiotic
Carbenicillin is a semi-synthetic penicillin antibiotic that primarily targets gram-negative bacteria through the inhibition of cell wall synthesis. It exhibits broad-spectrum antibacterial activity and is characterized by its relatively low toxicity towards plant tissues. Carbenicillin is commonly utilized in microbiological research and clinical applications to study bacterial growth and resistance mechanisms. -
Dianionic Cephem Antibiotic
Ceftibuten is a dianionic cephem antibiotic that exhibits potent antibacterial activity. It is effective in vitro against a variety of gram-negative bacteria and certain gram-positive pathogens. This compound is primarily used in research applications focused on antibiotic resistance and the mechanism of action of cephalosporins. -
Antibiotic
Eremomycin is a potent glycopeptide antibiotic that targets bacterial cell walls to inhibit growth. It exhibits significant antibacterial activity against Staphylococcus species and Bacillus subtilis ATCC6633, with minimal inhibitory concentrations ranging from 0.03 to 1.6 μg/mL. This compound is valuable in research applications focused on antibiotic resistance and the development of new antibacterial therapies. -
antibiotic
Spiramycin III is a macrolide antibiotic derived from Streptomyces ambofaciens, primarily targeting bacterial infections and Toxoplasma gondii. This compound exhibits notable antibacterial and antiparasitic activities, making it a valuable reagent for research applications focused on infectious diseases and parasitic challenges. Its versatile efficacy positions Spiramycin III as a critical tool in the study and treatment of various microbial infections. -
Antibiotic
Showdomycin is an antibiotic targeting bacterial ribosomes, inhibiting protein synthesis. It is produced by Streptomyces in response to the IM-2 inducer. Showdomycin exhibits potent antibacterial activity, making it valuable for research on microbial resistance mechanisms and the development of new antibiotic therapies. -
Antibiotic
Thiocillin I is a thiopeptide antibiotic that exhibits potent antibacterial activity against Gram-positive bacteria. It has been shown to have minimum inhibitory concentration (MIC) values of 2 μg/mL against Staphylococcus aureus, 0.5 μg/mL against Enterococcus faecalis, 4 μg/mL against Bacillus subtilis, and 0.5 μg/mL against Streptococcus pyogenes. Thiocillin I is primarily used in research applications focused on bacterial resistance and antibiotic efficacy studies. -
Antibiotic
Gilvocarcin V is an antibiotic that targets bacterial cells, exhibiting strong antibacterial activity. Isolated from Actinomycete, it also demonstrates anti-tumor properties, making it a valuable reagent for cancer research. Its dual functionality supports investigations into microbial resistance and tumor biology, contributing significantly to the understanding of these critical areas. -
Antibiotic
Clovibactin is an antibiotic that effectively targets drug-resistant bacterial pathogens with no detectable resistance. This compound functions by inhibiting cell wall synthesis, specifically targeting the pyrophosphate of peptidoglycan precursors. Its unique mechanism makes Clovibactin a valuable tool for researching antibiotic resistance and developing new therapeutic strategies against challenging bacterial infections. -
Antibiotic
(5S)-Neosamine C is an aminocyclic alcohol antibiotic that targets bacterial cell wall synthesis through its unique cyclized structure. This compound is derived from microbial secondary metabolites and serves as a key precursor in the biosynthesis of Neomycins. Its biological activity highlights its potential applications in antibiotic research and development. -
β-lactam Antibiotic
Cefoselis is a fourth-generation cephalosporin that functions as a β-lactam antibiotic, targeting bacterial cell wall synthesis. It demonstrates potent activity against a broad spectrum of Gram-positive and Gram-negative bacteria. Additionally, Cefoselis is capable of penetrating the blood-brain barrier, making it valuable for research applications related to central nervous system infections. -
Antibiotic
Norvancomycin hydrochloride is a glycopeptide antibiotic that targets bacterial cell wall synthesis. It demonstrates potent activity against various strains of Staphylococcus aureus and Staphylococcus epidermidis. This compound is primarily utilized in infection research to study antibiotic resistance and the mechanisms of bacterial pathogenicity. -
Antibiotic
4-Aminosalicylic acid hemicalcium acts primarily as an inhibitor of dihydrofolate reductase (DHFR) and serves as an effective antituberculous agent. This compound exhibits notable anti-inflammatory properties, making it a valuable tool for research into inflammatory bowel disease (IBD). Its oral bioavailability enhances its utility in various biochemical and pharmacological studies. -
Cephem Antibiotic
Cefcapene pivoxil is a prodrug form of Cefcapene, functioning as a third-generation cephalosporin antibiotic. It exhibits a broad spectrum of antibacterial activity, making it valuable for in vitro and in vivo studies of bacterial infections. Additionally, Cefcapene pivoxil has potential applications in research related to palmoplantar pustulosis (PPP). -
Antibiotic
Coformycin is a nucleoside antibiotic that primarily inhibits adenosine deaminase (ADA), an enzyme crucial for purine metabolism. This compound exhibits significant anti-tumor and anti-bacterial properties, making it valuable for research in cancer treatment and infectious disease. Coformycin's ability to modulate adenosine levels underscores its potential in therapeutic applications related to cellular proliferation and immune response. -
Antibiotic
L-Amoxicillin is a broad-spectrum antibiotic primarily targeting bacterial cell wall synthesis through inhibition of penicillin-binding proteins. It is widely utilized in clinical settings, often in conjunction with the β-lactamase inhibitor potassium clavulanic acid to enhance antimicrobial efficacy. Rigorous analysis methods for L-Amoxicillin have been developed, adhering to International Conference on Harmonization (ICH) guidelines, ensuring accuracy in quality assessment. Additionally, stability studies and stress testing have been conducted to determine the compound's robustness in various formulations, reinforcing its application in infection management. -
Antibiotic
Fosfomycin is a broad-spectrum antibiotic that irreversibly inhibits MurA, a crucial enzyme in bacterial cell wall synthesis. This compound effectively penetrates the blood-brain barrier and demonstrates significant antimicrobial activity against a variety of bacterial strains, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. Fosfomycin is widely used in research for studying bacterial resistance mechanisms and developing novel therapeutic strategies. -
Antibiotic
Cefoperazone dihydrate is a semisynthetic cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against various Gram-positive and Gram-negative pathogens. This compound is utilized in microbiological research and clinical settings for the treatment of infections, making it valuable for studies on antibiotic resistance and therapeutic efficacy. -
Antibiotic
Pibrozelesin is a derivative of the antibiotic Duocarmycin B2, primarily targeting DNA cleavage. It demonstrates potent antitumor activity, inhibiting the proliferation of H69 cells with an IC50 of 1.9 μM. Upon activation by carboxyl esterase, Pibrozelesin induces DNA strand breaks, making it a valuable tool for cancer research and the study of DNA damage mechanisms. -
Antibiotic
Gatifloxacin sesquihydrate is a potent fluoroquinolone antibiotic that primarily targets bacterial type II topoisomerases. It exhibits broad-spectrum antibacterial activity, demonstrating significant inhibition of S. aureus topoisomerase IV and E. coli DNA gyrase with IC50 values of 13.8 μg/ml and 0.109 μg/ml, respectively. This compound is particularly useful in research related to bacterial infections and may serve as a therapeutic agent for conditions such as bacterial conjunctivitis. -
Antibiotic
Secnidazole hemihydrate is an orally active azole antibiotic that targets bacterial virulence through its amelioration of Serratia marcescens. This compound acts as an analog of acylhomoserine lactones, effectively inhibiting quorum sensing and reducing the pathogenesis of Pseudomonas aeruginosa. Secnidazole hemihydrate demonstrates antimicrobial activity against a range of anaerobic Gram-negative and Gram-positive bacteria in vitro. Its versatile applications in research include the study of diseases such as amoebiasis, giardiasis, and bacterial vaginitis. -
Antibiotic
Teixobactin is a potent antibiotic that primarily targets cell wall synthesis in bacteria. It demonstrates significant antibacterial activity against gram-negative bacteria by binding to the conserved motifs of lipid II and lipid III. This mechanism of action makes Teixobactin a valuable reagent for research focused on bacterial resistance and the development of new antibiotic therapies. -
Antibiotic
Sitafloxacin hydrochloride is a potent fluoroquinolone antibiotic that functions by inhibiting bacterial DNA gyrase and topoisomerase IV, ultimately disrupting bacterial replication. It exhibits significant antibacterial activity against a wide spectrum of both gram-positive and gram-negative bacteria, including anaerobic organisms and atypical pathogens. This compound is primarily applied in research related to respiratory and urinary tract infections. -
Antibiotic
Amoxicillin arginine is an antibiotic that effectively inhibits cell wall biosynthesis by targeting polypeptide synthesis, leading to the disruption of bacterial growth. With good oral absorption and a broad spectrum of antimicrobial activity, it is utilized in various research applications related to bacterial infections and resistance mechanisms. This compound serves as an important tool for studying the pharmacological effects of β-lactam antibiotics in both clinical and laboratory settings. -
Antibiotic
Zanamivir (hydrate)(5:1) is a potent inhibitor of influenza viral neuraminidase, exhibiting IC50 values of 0.95 nM for influenza A and 2.7 nM for influenza B. This compound is widely employed in antiviral research to elucidate the mechanisms of viral infection and to develop therapeutic strategies against influenza viruses. Its high inhibitory efficacy makes it a valuable tool for studying the effects of neuraminidase inhibition in both laboratory and clinical settings. -
Cephalosporin Antibiotic
Cefotiam is a parenteral cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, making it a valuable reagent for research in microbiology and infectious disease studies. This compound is commonly used in evaluating bacterial susceptibility and understanding the mechanisms of antibiotic resistance. -
Antibiotic
Netilmicin is a broad-spectrum semisynthetic aminoglycoside antibiotic targeting bacterial protein synthesis. It demonstrates significant antibacterial activity against aminoglycoside-susceptible gram-negative strains as well as aminoglycoside-resistant strains, including Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with a minimum inhibitory concentration (MIC) ranging from 0.125 to 8 μg/mL. This compound is widely used in research applications focusing on antimicrobial susceptibility and resistance mechanisms. -
Antibiotic
Cefepime chloride is a broad-spectrum cephalosporin antibiotic that effectively targets both Gram-positive and Gram-negative aerobic bacteria. Its ability to penetrate the blood-brain barrier makes it a valuable agent in the treatment of central nervous system infections. Additionally, it is noted for its neurotoxic effects, making it relevant for studies investigating antimicrobial toxicity and resistance mechanisms. -
Antibacterial Antibiotic
Tebipenem pivoxil hydrochloride is an orally active antibacterial agent that targets penicillin-binding proteins (PBPs) to inhibit cell wall synthesis in pathogenic bacteria. This mechanism of action makes it effective against a broad spectrum of Gram-positive and Gram-negative organisms. It is utilized in research applications focused on antibiotic resistance and the development of novel antibacterial therapies. -
Cephalosporin Antibiotic
Cephalexin hydrochloride monohydrate is a semisynthetic cephalosporin antibiotic that primarily targets penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis. It exhibits a wide antibacterial spectrum, effective against various gram-positive and gram-negative bacteria. This compound is utilized in research related to bacterial infections, including pneumonia, strep throat, and bacterial endocarditis. -
Dianionic Cephem Antibiotic
Ceftibuten monohydrate is a dianionic cephem antibiotic that exhibits potent antibacterial activity. It is effective against a broad spectrum of gram-negative bacteria and select gram-positive strains. Ceftibuten is primarily utilized in research applications focusing on antibiotic resistance and the pharmacological evaluation of cephalosporins. Its oral bioavailability makes it a valuable compound for studying systemic infection models. -
Antibiotic
Sitafloxacin monohydrate is a potent fluoroquinolone antibiotic that exhibits strong antibacterial activity against a wide spectrum of both gram-positive and gram-negative bacteria, including anaerobic organisms and atypical pathogens. Its antichlamydial properties make it a valuable reagent in the study of various infections. Sitafloxacin monohydrate is particularly relevant in research focused on respiratory and urinary tract infections. -
Cephalosporin Antibiotic
Cephalexin (lysine) is a semisynthetic cephalosporin antibiotic that primarily targets penicillin-binding proteins (PBPs) to disrupt bacterial cell wall synthesis. This compound exhibits broad-spectrum antibacterial activity against a range of gram-positive and gram-negative bacteria. Cephalexin (lysine) is used in research applications related to various infections, including pneumonia, streptococcal throat infections, and bacterial endocarditis. -
β-lactam Antibiotic
Dicloxacillin is a β-lactam antibiotic belonging to the penicillin family, primarily targeting Gram-positive bacteria. It demonstrates effectiveness against β-lactamase-producing organisms, including Staphylococcus aureus. This compound is widely utilized in research and clinical applications to investigate bacterial resistance mechanisms and evaluate the efficacy of antibacterial treatments. -
Antibiotic
A83016A is a kinamycin-type antibiotic that inhibits bacterial growth by targeting essential cellular processes. It exhibits a minimum inhibitory concentration (MIC) of 4 µg/ml against Enterococcus faecium, demonstrating its potent antibacterial activity. This compound is suitable for research applications focused on antibiotic resistance and efficacy studies in microbiology. -
Antibiotic
Antibiotic SF-2132 is a peptide antibiotic derived from Nocardiopsis sp., demonstrating potent inhibitory activity against β-lactam antibiotic-resistant strains, including Pseudomonas and Escherichia. This compound is particularly valuable in research aimed at addressing antibiotic resistance and investigating novel antimicrobial mechanisms. Its efficacy against resistant pathogens makes it a crucial tool for studies in microbiology and infectious disease. -
Antibiotic
Aurodox is an antibiotic derived from a variant of Streptomyces, primarily targeting gram-positive bacteria. It exhibits potent antibacterial activity while demonstrating low toxicity in murine models. Aurodox is utilized in research applications related to antibiotic efficacy and potential growth promotion in agricultural settings. -
Cephalosporin Antibiotic
Cefetecol is a broad-spectrum cephalosporin antibiotic that targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall synthesis, leading to cell lysis. In addition to its antibacterial properties, Cefetecol also acts as an α-glucosidase inhibitor, demonstrating in vivo anti-diabetic activity in diabetic mouse models. This compound is suitable for research applications in both antibacterial and anti-diabetic studies.
