Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
DL-Lanthionine is an amino acid that functions as a crucial monosulfide analog of cystine. It serves as a key component in the structure of peptide antibiotics known as lantiobiotics, which include prominent members like nisin and subtilin. DL-Lanthionine is instrumental in researching antibiotic mechanisms and developing novel antimicrobial agents with therapeutic potential. -
Antibiotic
A-54556A (ADEP 1) is an acyldepsipeptide antibiotic that primarily targets bacterial protein synthesis. It exhibits potent antibacterial activity against a diverse array of Gram-positive bacteria, making it a valuable tool for research on bacterial resistance and antibiotic efficacy. A-54556A is utilized in studies exploring mechanism of action and the development of novel antimicrobial agents. -
Antibiotic
Carbenicillin is a semi-synthetic penicillin antibiotic that primarily targets gram-negative bacteria through the inhibition of cell wall synthesis. It exhibits broad-spectrum antibacterial activity and is characterized by its relatively low toxicity towards plant tissues. Carbenicillin is commonly utilized in microbiological research and clinical applications to study bacterial growth and resistance mechanisms. -
Dianionic Cephem Antibiotic
Ceftibuten is a dianionic cephem antibiotic that exhibits potent antibacterial activity. It is effective in vitro against a variety of gram-negative bacteria and certain gram-positive pathogens. This compound is primarily used in research applications focused on antibiotic resistance and the mechanism of action of cephalosporins. -
Antibiotic
Eremomycin is a potent glycopeptide antibiotic that targets bacterial cell walls to inhibit growth. It exhibits significant antibacterial activity against Staphylococcus species and Bacillus subtilis ATCC6633, with minimal inhibitory concentrations ranging from 0.03 to 1.6 μg/mL. This compound is valuable in research applications focused on antibiotic resistance and the development of new antibacterial therapies. -
antibiotic
Spiramycin III is a macrolide antibiotic derived from Streptomyces ambofaciens, primarily targeting bacterial infections and Toxoplasma gondii. This compound exhibits notable antibacterial and antiparasitic activities, making it a valuable reagent for research applications focused on infectious diseases and parasitic challenges. Its versatile efficacy positions Spiramycin III as a critical tool in the study and treatment of various microbial infections. -
Antibiotic
Showdomycin is an antibiotic targeting bacterial ribosomes, inhibiting protein synthesis. It is produced by Streptomyces in response to the IM-2 inducer. Showdomycin exhibits potent antibacterial activity, making it valuable for research on microbial resistance mechanisms and the development of new antibiotic therapies. -
Antibiotic
Thiocillin I is a thiopeptide antibiotic that exhibits potent antibacterial activity against Gram-positive bacteria. It has been shown to have minimum inhibitory concentration (MIC) values of 2 μg/mL against Staphylococcus aureus, 0.5 μg/mL against Enterococcus faecalis, 4 μg/mL against Bacillus subtilis, and 0.5 μg/mL against Streptococcus pyogenes. Thiocillin I is primarily used in research applications focused on bacterial resistance and antibiotic efficacy studies. -
Antibiotic
Gilvocarcin V is an antibiotic that targets bacterial cells, exhibiting strong antibacterial activity. Isolated from Actinomycete, it also demonstrates anti-tumor properties, making it a valuable reagent for cancer research. Its dual functionality supports investigations into microbial resistance and tumor biology, contributing significantly to the understanding of these critical areas. -
Antibiotic
Clovibactin is an antibiotic that effectively targets drug-resistant bacterial pathogens with no detectable resistance. This compound functions by inhibiting cell wall synthesis, specifically targeting the pyrophosphate of peptidoglycan precursors. Its unique mechanism makes Clovibactin a valuable tool for researching antibiotic resistance and developing new therapeutic strategies against challenging bacterial infections. -
Antibiotic
(5S)-Neosamine C is an aminocyclic alcohol antibiotic that targets bacterial cell wall synthesis through its unique cyclized structure. This compound is derived from microbial secondary metabolites and serves as a key precursor in the biosynthesis of Neomycins. Its biological activity highlights its potential applications in antibiotic research and development. -
β-lactam Antibiotic
Cefoselis is a fourth-generation cephalosporin that functions as a β-lactam antibiotic, targeting bacterial cell wall synthesis. It demonstrates potent activity against a broad spectrum of Gram-positive and Gram-negative bacteria. Additionally, Cefoselis is capable of penetrating the blood-brain barrier, making it valuable for research applications related to central nervous system infections. -
Antibiotic
Norvancomycin hydrochloride is a glycopeptide antibiotic that targets bacterial cell wall synthesis. It demonstrates potent activity against various strains of Staphylococcus aureus and Staphylococcus epidermidis. This compound is primarily utilized in infection research to study antibiotic resistance and the mechanisms of bacterial pathogenicity. -
Antibiotic
4-Aminosalicylic acid hemicalcium acts primarily as an inhibitor of dihydrofolate reductase (DHFR) and serves as an effective antituberculous agent. This compound exhibits notable anti-inflammatory properties, making it a valuable tool for research into inflammatory bowel disease (IBD). Its oral bioavailability enhances its utility in various biochemical and pharmacological studies. -
Cephem Antibiotic
Cefcapene pivoxil is a prodrug form of Cefcapene, functioning as a third-generation cephalosporin antibiotic. It exhibits a broad spectrum of antibacterial activity, making it valuable for in vitro and in vivo studies of bacterial infections. Additionally, Cefcapene pivoxil has potential applications in research related to palmoplantar pustulosis (PPP). -
Antibiotic
Coformycin is a nucleoside antibiotic that primarily inhibits adenosine deaminase (ADA), an enzyme crucial for purine metabolism. This compound exhibits significant anti-tumor and anti-bacterial properties, making it valuable for research in cancer treatment and infectious disease. Coformycin's ability to modulate adenosine levels underscores its potential in therapeutic applications related to cellular proliferation and immune response. -
Antibiotic
L-Amoxicillin is a broad-spectrum antibiotic primarily targeting bacterial cell wall synthesis through inhibition of penicillin-binding proteins. It is widely utilized in clinical settings, often in conjunction with the β-lactamase inhibitor potassium clavulanic acid to enhance antimicrobial efficacy. Rigorous analysis methods for L-Amoxicillin have been developed, adhering to International Conference on Harmonization (ICH) guidelines, ensuring accuracy in quality assessment. Additionally, stability studies and stress testing have been conducted to determine the compound's robustness in various formulations, reinforcing its application in infection management. -
Antibiotic
Fosfomycin is a broad-spectrum antibiotic that irreversibly inhibits MurA, a crucial enzyme in bacterial cell wall synthesis. This compound effectively penetrates the blood-brain barrier and demonstrates significant antimicrobial activity against a variety of bacterial strains, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. Fosfomycin is widely used in research for studying bacterial resistance mechanisms and developing novel therapeutic strategies. -
Antibiotic
Cefoperazone dihydrate is a semisynthetic cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits a broad spectrum of antibacterial activity against various Gram-positive and Gram-negative pathogens. This compound is utilized in microbiological research and clinical settings for the treatment of infections, making it valuable for studies on antibiotic resistance and therapeutic efficacy. -
Antibiotic
Pibrozelesin is a derivative of the antibiotic Duocarmycin B2, primarily targeting DNA cleavage. It demonstrates potent antitumor activity, inhibiting the proliferation of H69 cells with an IC50 of 1.9 μM. Upon activation by carboxyl esterase, Pibrozelesin induces DNA strand breaks, making it a valuable tool for cancer research and the study of DNA damage mechanisms. -
Antitumor Antibiotic
Saintopin is an antitumor antibiotic that selectively inhibits DNA topoisomerases I and II, key enzymes involved in DNA replication and transcription. By inducing DNA cleavage, Saintopin disrupts the integrity of the genetic material, leading to apoptosis in cancer cells. This compound is utilized in research focused on cancer biology, particularly in studies involving mechanisms of chemotherapy resistance and DNA repair processes. -
Antibiotic Agent
Sulfadimethoxypyrimidine-d4 is a deuterium-labeled derivative of Sulfadimethoxypyrimidine, a sulfonamide antibiotic known for its broad-spectrum antibacterial activity. This compound acts by inhibiting bacterial dihydropteroate synthase, a key enzyme in folate biosynthesis, thereby disrupting DNA synthesis and bacterial growth. It is valuable for pharmacokinetic studies and metabolic research concerning sulfonamide antibiotics. -
Quinone Antibiotic
Granaticinic acid is a quinone antibiotic derived from Streptomyces thermoviolaceus NT1. It exhibits significant anti-gram-positive bacterial activity, making it a valuable compound for researching bacterial infections. Its unique mechanism of action provides insights into antibiotic resistance and the development of new therapeutic agents. -
Non-beta-lactam Antibiotic
Lactivicin is a non-beta-lactam antibiotic that exhibits beta-lactam-like activity by binding to penicillin-binding proteins (PBPs). It demonstrates moderate efficacy against a broad spectrum of Gram-negative bacteria and high effectiveness against Gram-positive bacteria. This compound is valuable for research in antibiotic resistance and the mechanisms of bacterial cell wall synthesis. -
Antibiotic
Griseolic acid C, an antibiotic compound, is identified as a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase (EC 3.1.4.17) with an IC50 of 0.12 μM, as demonstrated in studies utilizing rat brain extracts. Isolated from Streptomyces griseoaurantiacus SANK43894, Griseolic acid C exhibits significant biological activity that may be beneficial in various research applications related to cellular signaling and microbial resistance. -
Lipopeptide Antibiotic
Friulimicin D is a lipopeptide antibiotic derived from the actinomycete Actinoplanes friuliensis. It demonstrates significant antibacterial activity against a range of Gram-positive bacteria. Research applications include the study of bacterial resistance mechanisms and the potential development of novel antimicrobial therapies. -
Antibiotic
Istamycin Y0 is an aminoglycoside antibiotic with primary activity against bacterial ribosomes. Isolated from Streptomyces tenjimariensis ATCC 31603, it exhibits limited antibacterial efficacy against select bacterial strains. Istamycin Y0 is primarily used in microbiological research to study antibiotic resistance mechanisms and the pharmacodynamics of aminoglycosides. -
MRSA Antibiotic
MRSA Antibiotic 2 selectively targets methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. This compound demonstrates enhanced efficacy against Gram-positive bacteria while exhibiting minimal impact on Gram-negative bacteria and human cells. It is a valuable tool in the study of antibiotic resistance and the development of new therapeutic strategies for treating MRSA infections. -
Antibiotic
Sannamycin J is an aminoglycoside antibiotic that exhibits antimicrobial properties. Isolated from Streptomyces sannanensis sp. KC-7038, it demonstrates weak antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound serves as a valuable tool for research in antibiotic mechanisms and microbial resistance studies. -
Antibiotic
Trinactin is a macrotetrolide antibiotic that displays potent antibacterial activity through the disruption of bacterial cell membranes. Additionally, it functions as a cation carrier, facilitating ion transport across cellular membranes. This compound is significant for research applications focused on antibiotic development, cellular ion exchange mechanisms, and studying the effects of ionophore activity in various biological systems. -
Antibiotic
2'''-Hydroxychlorothricin is an antibiotic derived from the chlorothricin group, primarily targeting bacterial infections. Isolated from Streptomyces sp. K818, it exhibits anti-tumor properties and has been shown to extend the survival of ICR mice inoculated with Ehrlich cancer cells. This compound serves as a valuable tool in cancer research and microbiological studies focusing on antibiotic efficacy and tumor treatment. -
Antibiotic Intermediate
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics, targeting bacterial cell wall synthesis. It exhibits significant antibacterial activity and serves primarily in the synthesis of other antibiotics, such as Cefaclor and Cefprozil. This compound is valuable in microbiological research and the development of cephalosporin-based therapeutics. -
Antibiotic
Phenelfamycins C is an antibiotic derived from Streptomyces violaceoniger strains AB 9991-80 and AB 1047T-33. Its primary mechanism involves targeting and inhibiting the growth of eutrophic bacteria, demonstrating notable antibacterial activity. This compound is valuable for research applications focused on antibiotic development and studies of bacterial resistance mechanisms. -
Antibiotic
Sannamycin E is an aminoglycoside antibiotic derived from Streptomyces sannanensis KC-7038. It exhibits weak antibacterial activity primarily against Gram-positive bacteria. This compound is useful in research applications focused on antibiotic efficacy and resistance mechanisms. -
Antibiotic
2-Hydroxyaclacinomycin B is an anthracycline antibiotic known for its ability to inhibit RNA synthesis. Isolated from Streptomyces galilaeus A-862 (FERM BP-45), this compound exhibits significant anti-tumor activity. It serves as a valuable tool in cancer research, enabling studies focused on mechanisms of action and therapeutic potential within oncology. -
Antibiotic
Enopeptin A is a depsipeptide antibiotic primarily targeting Gram-positive and certain Gram-negative bacteria. Isolated from Streptomyces sp. RK-1051, it demonstrates potent activity against methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 25 μg/mL. Additionally, it exhibits efficacy against mutant strains of Escherichia coli and Pseudomonas aeruginosa, with MICs of 200 μg/mL. Enopeptin A is not effective against fungal pathogens, making it a valuable compound for studies focused on antibiotic resistance and bacterial infections. -
Antibiotic
Phenelfamycins D is an antibiotic derived from the actinobacteria Streptomyces violaceoniger AB 9991-80 and AB 1047T-33. It exhibits potent anti-eutrophic bacterial activity, making it a valuable tool for researching bacterial growth inhibition and antibiotic efficacy. Researchers can utilize Phenelfamycins D to explore its biological mechanisms and potential therapeutic applications in combating bacterial infections. -
Antibiotic
Saccharocarcin A is an antibiotic that targets a variety of bacterial and fungal pathogens. It has demonstrated activity against Mycobacterium luteus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans in disc diffusion assays. Additionally, Saccharocarcin A significantly inhibits Chlamydia trachomatis infection by 88% at a concentration of 0.5 μg/mL, while exhibiting low cytotoxicity in McCoy cells, making it a valuable reagent for studying infectious diseases and microbial resistance. -
Carbapenem Antibiotic
Tomopenem is a parenteral carbapenem antibiotic known for its extended half-life and broad-spectrum efficacy against various bacterial species. It exhibits potent antibacterial activity with a MIC90 ranging from 0.06 to 4 µg/mL across 293 clinical isolates, effectively targeting both aerobic and anaerobic organisms. Tomopenem is suitable for research applications focused on combating resistant bacterial infections and studying the mechanisms of action of carbapenem antibiotics. -
Antibiotic Agent
OES2-0017 is an antibiotic agent that targets spermine/spermidine acetyltransferase (SpeG) with an IC50 of 34.82 μM. This compound exhibits significant activity in inhibiting growth through low micromolar concentrations, demonstrating potent synergy with polyamines. At elevated concentrations, OES2-0017 disrupts bacterial membrane integrity, making it a valuable reagent for investigating bacterial growth inhibition mechanisms and polyamine metabolism in microbial research. -
Antibiotic
Respinomycin A1 is a natural antibiotic derived from Streptomyces sp. RK-483, exhibiting antimicrobial activity against various bacterial strains. This compound has been shown to induce differentiation in leukemic K-562 cells, highlighting its potential utility in cancer research and therapeutic development. Its unique mechanism of action makes Respinomycin A1 a valuable tool for investigating cellular differentiation and the pathways involved in leukemia. -
Antibiotic
Andrimid is a lipoacyl peptide that functions as an antibiotic through its action on bacterial cell envelope synthesis. It demonstrates significant antimicrobial activity, making it a valuable compound for researching antibiotic mechanisms and resistance. Additionally, Andrimid has potential applications in both biomedical research and agricultural biotechnology, particularly in developing strategies for disease control. -
Antibiotic
Cefonicid monosodium is a long-acting cephalosporin antibiotic that primarily targets bacterial cell wall synthesis. It possesses broad-spectrum antimicrobial activity, effectively combating a range of Gram-positive and Gram-negative bacteria. Additionally, Cefonicid acts as a noncompetitive inhibitor of class I β-lactamase, with a Ki value of 0.8 μM, making it a valuable reagent for research on bacterial infections and antibiotic resistance. -
Antibiotic
Neohydroxyaspergillic acid is an antibiotic that exhibits activity against specific bacteriophages. This compound can be utilized in research focusing on antibacterial mechanisms and the interaction between antibiotics and bacteriophages. Its potential applications extend to studying resistance and susceptibility patterns in microbial populations. -
natural cyclic oligopeptide antibiotic
Antibiotic that inhibits bacterial protein synthesis. Inhibits mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery and the activity of initiation factor 2 (IF-2). Antitumor agent; induces cell cycle arrest and apoptosis in breast cancer cells via downregulation of FOXM1 expression. -
Broad-spectrum antibiotic
Cefadroxil, also known as Duricef, is an antibiotic effective against pyodermic skin diseases, such as Staphylococcus aureus and Streptococcus pyogenes. -
cephalosporin antibiotic
Cefuroxime axetil is a second generation cephalosporin antibiotic with a broad spectrum activity against Gram positive and Gram negative bacteria. -
Antibiotic
Ceforanide is a semi-synthetic, broad-spectrum, beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. -
antibiotic
Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas -
broad-spectrum antibiotic
Amoxicillin Trihydrate is a broad-spectrum antibiotic. It binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Inactivated PBP interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.
