Catalog No.
Product Name
Application
Product Information
Citations
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Antimycobacterial Drug
Antituberculosis agent-7 is an oxetanyl-quinoline derivative primarily targeting mycobacterial infections. It exhibits potent antimycobacterial activity, demonstrating a minimum inhibitory concentration (MIC) of 3.41 μM against Mycobacterium tuberculosis H37Rv. Additionally, it displays notable antibacterial effects against Proteus mirabilis with an MIC of 31.25 μM and antifungal activity against Aspergillus niger with an MIC of 62.5 μM. This compound holds potential for research in antimicrobial susceptibility and drug development against various infectious diseases. -
Antibacterial Peptide
Metchnikowin is an antibacterial peptide derived from fruit flies, exhibiting potent antimicrobial properties against both bacteria and fungi. Its activity is regulated through the TOLL and IMD signaling pathways, making it a valuable tool for studying immune responses in various infectious conditions. This peptide is widely utilized in research focused on host defense mechanisms and the development of novel antimicrobial agents. -
Anti-bacterial Peptide
Pseudin-2 is an antimicrobial peptide derived from the skin of the South American paradoxical frog, Pseudis paradoxa. It exhibits potent growth inhibition against Gram-negative bacteria, making it a valuable tool for antibacterial research. Pseudin-2 may be utilized in studies aimed at understanding antimicrobial mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
PK-10 is a synergistic antibacterial agent that combines the active components of Fluconazole, exhibiting potent antifungal activity against various strains of Fluconazole-resistant Candida albicans. This compound effectively inhibits hyphae formation and induces the accumulation of reactive oxygen species, leading to mitochondrial dysfunction. Additionally, PK-10 disrupts mitochondrial membrane potential and decreases intracellular ATP levels, highlighting its potential applications in antifungal research and therapeutic development. -
Antibacterial Compound
Di-O-methylhonokiol is a natural phenolic compound with notable antibacterial properties. It exhibits significant activity against Gram-positive bacteria, acid-fast bacilli, and various yeast and filamentous fungi. This compound is valuable for research applications focused on fungal infections and the development of antibacterial agents. -
Antibacterial Agent
(±)9-HpODE is a long-chain lipid hydroperoxide derived from the peroxidation of linoleic acid. This compound can induce the oxidation of intracellular glutathione (GSH), leading to alterations in cellular redox state. Additionally, (±)9-HpODE demonstrates antibacterial and antifungal activity, making it a valuable reagent for research into microbial pathogenesis and oxidative stress responses. -
Antibacterial Agent
4-Methylbenzohydrazide is an antibacterial agent that exerts its activity against a range of microbial targets. It demonstrates a potent minimum inhibitory concentration (pMIC) value of 1.38 against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Aspergillus niger. This compound is suitable for research applications focused on developing antibacterial therapies and studying microbial resistance mechanisms. -
Antibacterial Agents
Benzoic acid lithium is an aromatic compound utilized primarily for its antibacterial properties. It effectively inhibits the growth of bacteria and fungi, making it a valuable preservative in various applications, including food, beverages, and cosmetics. This compound is widely used in research to study antimicrobial mechanisms and develop new preservative formulations. -
Antibacterial Agent
Deacylketoconazole is an orally active metabolite of ketoconazole, primarily functioning as an antibacterial agent. This compound demonstrates notable antifungal and antibacterial activities, making it relevant in the study of infectious diseases. Additionally, deacylketoconazole exhibits cytotoxic effects in rat hepatocytes, providing insights into its potential impact on liver function. It serves as a valuable tool in research focused on antimicrobial efficacy and cellular toxicity. -
Bacterial Inhibitor
Bafilomycin B1 is a macrolide antibiotic that targets vacuolar H+-ATPases (V-ATPases). It exhibits neuroprotective properties against Chloroquine-induced cell death and can significantly inhibit the accumulation of lipid droplets induced by oxidized low-density lipoprotein (LDL). Bafilomycin B1 is valuable for research focused on bacterial inhibition and studying lipid metabolism and cellular stress responses. -
Antibacterial Agent
L18-MDP is a derivative of muramyl dipeptide, functioning primarily as an antibacterial agent. It exhibits significant antibacterial activity, making it a valuable candidate for research in the treatment of bacterial and fungal infections. Its mechanism of action involves immune system stimulation, potentially enhancing host defense responses against microbial pathogens. -
Bacterial Inhibitor
Robinetin, a naturally occurring flavonoid, primarily acts as a bacterial inhibitor. This compound exhibits diverse biological activities, including antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant properties. Additionally, Robinetin has demonstrated the ability to inhibit lipid peroxidation and protein glycosylation, making it valuable for various research applications in microbiology and biochemistry. -
Bacterial Inhibitor
Tricyclazole is a pentaketone compound that acts as a bacterial inhibitor primarily by disrupting melanin biosynthesis in fungi. This unique fungicide is effective in controlling rice blast disease by altering the structure and function of fungal cell walls, thereby reducing pathogenicity and penetration. Tricyclazole’s mechanism of action also highlights its potential for studying fungal biology and the effects of melanin on fungal virulence. -
Anti-bacterial/fungal Agent
Eugenol acetate is an antibacterial and antifungal agent that targets multiple biological pathways. It exhibits significant anti-inflammatory and antioxidant properties, acting through the inhibition of NF-κB while enhancing the expression of tumor suppressor proteins such as p53 and p21 (WAF1). Eugenol acetate is also implicated in cancer research, demonstrating the ability to prevent chemically induced skin cancer, inhibit cancer cell proliferation, and induce apoptosis in various cancer cell lines. Its diverse biological activities make it a valuable tool in chemical and biomedical research applications. -
Bacterial/Fungal Inhibitor
2-Methoxybenzaldehyde, also known as o-Anisaldehyde, serves as a bacterial and fungal inhibitor, with a BA50 value of 0.19 against Salmonella. This compound is utilized in the investigation of bacterial and fungal infectious diseases, providing insights into their mechanisms and potential therapeutics. Its effectiveness in hindering microbial growth makes it a valuable reagent for microbiological research. -
Antibacterial Agent
Germacrene D is an antibacterial agent derived from Solidago canadensis. It exhibits significant antibacterial and antifungal activities, demonstrating potential as an adjuvant in enhancing the efficacy of aminoglycosides and azoles. This compound is valuable for research applications focused on combating microbial infections and exploring synergistic effects in antimicrobial therapies. -
Antibacterial Agent
GI261520A functions as an antibacterial agent primarily by inhibiting the PhoQ phosphorylation pathway. This compound exhibits a dose-dependent suppression of PhoP/PhoQ activity and demonstrates an IC50 value of 3.2 μM in inhibiting pagC reporter expression levels. Additionally, GI261520A effectively reduces PhoQc autokinase activity by 80%, allowing it to penetrate eukaryotic cell membranes and target intravacuolar Salmonella, thereby preventing intramacrophage proliferation. It serves as a valuable tool for research into antibacterial mechanisms and intracellular bacterial behavior. -
Bacterial Inhibitor
Enoxacin is a fluoroquinolone antibacterial that primarily targets bacterial DNA gyrase and topoisomerase IV, with reported IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. It exhibits strong inhibitory activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin acts as a miRNA processing activator, facilitating siRNA-mediated mRNA degradation and promoting the biogenesis of endogenous miRNAs. Notably, Enoxacin serves as a cancer-specific growth inhibitor through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing, making it valuable for research in bacterial inhibition and cancer biology. -
Antibacterial Preservative
Imidazolidinyl urea functions as an antibacterial preservative by releasing formaldehyde through its decomposition. It exhibits broad-spectrum antibacterial activity, effectively inhibiting the growth of both gram-negative and gram-positive bacteria, as well as limiting yeast and mold proliferation. Additionally, it can be utilized in the formulation of multifunctional hydrogels for managing infectious wounds. Notably, Imidazolidinyl urea may also induce non-histaminergic allergic responses via the activation of MRGPRX2 in mast cells. -
Antibacterial Agent
Ornidazole is a nitroimidazole derivative primarily used as an antibacterial agent. It demonstrates anti-trichomonad activity and is effective against a range of anaerobic bacteria in vitro. Additionally, Ornidazole inhibits the Sonic hedgehog (Shh) signaling pathway and exhibits antitumor properties, making it a valuable tool in the investigation of conditions such as Crohn’s disease. -
Bacterial Inhibitor
X-Neu5Ac sodium is a neuraminidase substrate that facilitates the chromogenic assay of neuraminidase activity in bacterial expression systems. This compound has a Km value of 0.89 mM for neuraminidase, making it an effective tool for studying neuraminidase function and inhibition. Its use in research applications provides insights into bacterial mechanisms and potential therapeutic targets for bacterial infections. -
Antibacterial Agent
Domiphen bromide is a cationic quaternary ammonium salt primarily known for its antibacterial activity. It exhibits potent inhibition of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, and various bacterial phosphatases, making it versatile for medicinal applications. Due to its antibacterial and antimalarial properties, Domiphen bromide is utilized as a preservative and disinfectant and serves as a research tool in the study of bacterial infections such as pharyngitis, thrush, and oral ulcers. -
Bacterial Inhibitor
Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic that primarily targets bacterial growth by inhibiting dihydropteroate synthase and disrupting folate synthesis. This compound exhibits significant antibacterial activity and is primarily utilized in research applications focused on understanding bacterial infections and exploring antibiotic resistance mechanisms. Suitable for studies related to dermatological conditions, it aids in exploring therapeutic strategies for diseases like dermatitis herpetiformis. -
Bacterial Inhibitor
Enoxacin hydrate, a fluoroquinolone antibiotic, targets bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication with IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. This compound exhibits significant antibacterial activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin hydrate functions as an activator of miRNA processing, facilitating siRNA-mediated mRNA degradation and enhancing the biogenesis of endogenous miRNAs. Its unique mode of action also includes the inhibition of cancer cell growth through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing. -
Bacterial Inhibitor
Chlorprothixene hydrochloride functions as an antagonist of dopamine and histamine receptors, exhibiting Kis of 18 nM for hD1, 2.96 nM for hD2, 4.56 nM for hD3, 9 nM for hD5, and 3.75 nM for hH1 receptors. This compound demonstrates significant antipsychotic activity, making it a valuable tool for research into neuropharmacology and the mechanisms underlying psychotic disorders. Its receptor modulation also indicates potential applications in the study of bacterial inhibition mechanisms, providing insights into the interplay between neurotransmitter systems and microbial pathogenesis. -
Bacterial Inhibitor
Aeroplysinin 1 is a secondary metabolite with a primary target as a bacterial inhibitor. It exhibits significant antibiotic activity against Gram-positive bacteria and demonstrates antiviral efficacy against HIV-1, with an IC50 of 14.6 μM. Additionally, Aeroplysinin 1 possesses anti-inflammatory, anti-angiogenic, and anti-tumor properties, and has been shown to induce apoptosis in endothelial cells. This compound is valuable for research applications in microbiology, virology, and cancer studies. -
Antibacterial Growth Promoter
Nitrovin hydrochloride is an antibacterial growth promoter that targets thioredoxin reductase 1 (TrxR1) to induce reactive oxygen species (ROS)-mediated cell death. This compound exhibits both non-apoptotic and apoptotic-like mechanisms of action. It also demonstrates anticancer activity, with IC50 values ranging from 1.31 to 6.60 μM in various tumor and normal cell lines, making it a valuable tool for cancer research and therapeutic development. -
Bacterial/Fungal Inhibitor, Preservative Agent
Methylisothiazolinone hydrochloride is a bacterial and fungal inhibitor, primarily functioning as a preservative agent. It activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Research indicates that it may promote the development of atopic dermatitis in murine models by disrupting Th2/Th17 immune responses. Additionally, Methylisothiazolinone hydrochloride has been shown to cause mitochondrial damage in the endothelium of rat cerebral blood vessels, highlighting its cellular impact. -
Bacterial Inhibitor
K-252c is a staurosporine analog that selectively inhibits protein kinase C (PKC), exhibiting an IC50 value of 2.45 µM. This compound is known for its ability to induce apoptosis in human chronic myelogenous leukemia cells, making it a valuable tool in cancer research. Additionally, K-252c demonstrates inhibitory effects on β-lactamase, chymotrypsin, and malate dehydrogenase, further expanding its utility in studying bacterial resistance and enzyme activity. -
Antibacterial Agent
Lasalocid is an antibacterial and anticoccidial agent that functions as a feed additive in agricultural applications. It has demonstrated antitumor activity, suggesting potential utility in oncological research. Additionally, Lasalocid is orally bioactive, making it suitable for studies involving gastrointestinal absorption and pharmacokinetics. -
Bacterial Agent And Polyamine Transport System Inhibitor
AMXT-1501 is an antibacterial agent and polyamine transport system inhibitor that targets membrane phospholipids. It exhibits significant antibacterial activity against a range of multidrug-resistant Gram-positive and Gram-negative bacteria, specifically inhibiting capsular biosynthesis in Streptococcus pneumoniae. Additionally, AMXT-1501 interferes with ornithine decarboxylase and polyamine pathways, leading to the inhibition of neuroblastoma cell proliferation. Research applications include studies on multidrug-resistant bacterial infections, pneumococcal infections, and neuroblastoma therapeutics. -
Antibacterial Agent
Lasalocid sodium is an antibacterial and anticoccidial agent primarily utilized in veterinary medicine as a feed additive. This compound exhibits significant antitumor activity, demonstrating potential for additional therapeutic applications. Its oral bioactivity further enhances its utility in various research studies focused on microbial resistance and cancer biology. -
Bacterial Inhibitor
Citrinin is a mycotoxin known for its role as a bacterial inhibitor. It exhibits a range of biological activities, including the regulation of immune cell populations, induction of apoptosis and autophagy in immune cells, and modulation of toll-like receptor expression and cytokine production. Citrinin also induces oxidative stress, leading to apoptosis in oocytes, while low doses demonstrate neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. This compound's diverse mechanisms make it a valuable reagent for research in immunology, neurobiology, and antibacterial applications. -
Anti-bacterial Agent
Pinosylvin is a stilbenoid toxin derived from the heartwood of Pinus species, exhibiting significant anti-bacterial activity. As a resveratrol analogue, it has been shown to induce apoptosis and autophagy in leukemia cells, making it a valuable agent for research in cancer therapy and infectious disease studies. Its unique properties position Pinosylvin as a promising candidate for further exploration in the development of anti-microbial and anti-cancer compounds. -
Antibacterial Agent
5-Fluoroindole is a fluorinated indole derivative that serves as an antibacterial agent. It has been shown to induce reactive oxygen species (ROS) accumulation and initiate apoptosis in bacterial cells. 5-Fluoroindole effectively inhibits the growth of pan-susceptible Mycobacterium tuberculosis H37Rv strains and demonstrates significant bactericidal activity against Pseudomonas syringae pv. actinidiae, with an EC50 of 15.34 µg/mL. This compound is valuable for research focused on tuberculosis and bacterial infections in kiwifruit. Additionally, its fluorinated structure makes it suitable for protein labeling applications. -
Bacterial/Fungal Inhibitor, Preservative Agent
Methylisothiazolinone is a potent bacterial and fungal inhibitor with significant applications as a preservative agent. It activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Additionally, this compound is linked to the exacerbation of atopic dermatitis in mice through the disruption of Th2/Th17-related immune responses. Furthermore, Methylisothiazolinone has been shown to induce mitochondrial damage in the endothelium of rat cerebral blood vessels, highlighting its potential impact on vascular health. -
Bacterial Inhibitor
Oligomycin B is an antibiotic derived from marine Streptomyces, primarily acting as an inhibitor of ATP synthase in eukaryotic cells. Its mechanism of action leads to a decrease in ATP production, resulting in cellular stress and the induction of apoptosis. Oligomycin B is widely utilized in research focused on mitochondrial function, energy metabolism, and apoptosis-related studies. -
Bacterial Inhibitor
Lactoferrin (17-41) acetate is a peptide derived from residues 17-41 of bovine lactoferrin, primarily functioning as a bacterial inhibitor. It exhibits potent antimicrobial activity against various microorganisms, including Gram-positive and Gram-negative bacteria, viruses, protozoa, and fungi. In addition to its antimicrobial properties, Lactoferrin (17-41) acetate also demonstrates antitumor activities, making it a valuable reagent in studies related to infection control and cancer research. -
Antibacterial Agent
(±)-Trolline, also known as (±)-Oleracein E, is an isoquinoline alkaloid with notable antibacterial properties against respiratory pathogens. Additionally, it demonstrates antiviral activity against influenza viruses A and B. (±)-Trolline is also a potent inducer of hepatic stellate cell apoptosis, making it a valuable tool for studying liver fibrosis and associated liver disorders. -
Antibacterial Growth Promoter
Nitrovin is an antibacterial growth promoter that targets thioredoxin reductase 1 (TrxR1). It acts by inducing reactive oxygen species (ROS)-mediated non-apoptotic and apoptotic-like cell death. Nitrovin exhibits anticancer activity, demonstrating IC50 values ranging from 1.31 to 6.60 μM in various tumor and normal cell lines, making it a valuable tool for research in cancer and antibacterial studies. -
Antibacterial Agent
Antibacterial Agent 292 is a 3-pyrazolylindole derivative targeting bacterial pathogens. This compound exhibits potent inhibitory activity against Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv citri (Xac), with EC50 values of 2.54 and 3.49 μg/mL, respectively. It suppresses biofilm formation, bacterial motility, and extracellular polysaccharide production while inducing morphological changes and promoting ROS accumulation, leading to bacterial apoptosis. Additionally, it down-regulates genes associated with the type VI secretion system (T6SS), making it a valuable tool for research on rice bacterial blight and citrus canker. -
Bacterial
(-)-Isoledene primarily functions as an antibacterial agent, exhibiting significant antibacterial and anti-inflammatory activities. This natural organic compound has been investigated for its role in the synthesis of various compound intermediates, highlighting its potential applications in compound development and pharmaceutical research. Its diverse biological activity positions it as a valuable reagent for studies related to bacterial infections and inflammation. -
Bacterial Inhibitor
(Z)-Methyl tetradec-9-enoate functions as a bacterial inhibitor, primarily exerting its cytotoxic effects in human prostate cancer LNCaP cells through the induction of apoptosis and necrosis. Isolated from S. repens fruit extract, this compound also demonstrates antifungal activity, effectively inhibiting the germination of Candida albicans with a minimum inhibitory concentration (MIC) of 9 μM in vivo. Its applications extend to studies in both cancer research and microbiology, making it a valuable reagent for understanding cellular processes and developing therapeutic strategies. -
Bacterial Metabolite Xie
Collismycin A is a bacterial metabolite targeting multiple cellular pathways, originally isolated from Streptomyces. Exhibiting antibacterial, antiproliferative, and neuroprotective properties, it demonstrates activity against various bacteria and fungi (MICs ranging from 6.25 to 100 μg/mL). Notably, Collismycin A inhibits the proliferation of A549 lung, HCT116 colon, and HeLa cervical cancer cells, with IC50 values of 0.3, 0.6, and 0.3 μM, respectively, while demonstrating minimal impact on MDA-MB-231 breast cancer cells (IC50 > 100 μM). Furthermore, it forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, where the presence of iron ions can attenuate its antiproliferative effects in HeLa cells, and it exhibits protective effects against neuronal cell death in zebrafish larvae models. -
Antibacterial Agent/eEF2K Inhibitor
Cefatrizine is a broad-spectrum cephalosporin antibiotic that primarily targets bacterial infections while also acting as an eEF2K inhibitor. This compound exhibits anti-proliferative activity in human breast cancer cells, inducing endoplasmic reticulum stress and subsequent cell death. Cefatrizine is a valuable reagent for research applications in understanding mechanisms of cancer therapy and exploring antibacterial efficacy. -
Antibacterial Agent
Chlorhexidine acetate hydrate is a cationic antimicrobial agent that targets microbial cell membranes. By non-specifically binding to cell membrane phospholipids, it disrupts membrane integrity, leading to leakage of cellular contents and bacterial cell death. This compound exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Its ability to interfere with membrane permeability and induce protein precipitation makes it valuable for research applications focused on microbial growth inhibition and mechanisms of cell death. -
Antibacterial/anti-inflammatory Agent
Sinapaldehyde is a methoxyphenol that primarily functions as a selective COX-2 inhibitor with an IC50 of 47.8 µM. This compound exhibits notable antibacterial and anti-inflammatory properties, demonstrating efficacy against both Gram-positive and Gram-negative bacteria. Additionally, Sinapaldehyde possesses antioxidant activity through its ability to scavenge DPPH free radicals, with an IC50 of 172 μM, making it a valuable reagent for research in inflammation and microbial resistance. -
Antibacterial Agent
1-Tetradecanol is a straight-chain saturated fatty alcohol that serves as an effective antibacterial agent. Isolated from Myristica fragrans, it exhibits notable antibacterial and anti-inflammatory properties, particularly in the context of periodontitis. This compound can be utilized in research applications focusing on antimicrobial activity and the modulation of inflammatory responses. -
Antibacterial Agent
Terminolic acid is a pentacyclic triterpene glycoside that acts as an antibacterial agent. It exhibits significant antibacterial activity against Staphylococcus aureus, Escherichia coli, and Enterococcus faecalis, with minimum inhibitory concentrations (MICs) ranging from 64 to 256 μg/mL. Terminolic acid also demonstrates the ability to inhibit pro-inflammatory cytokines by binding to the receptor active sites of IL-1β and IL-6, contributing to a reduction in IL-8 levels. This compound is utilized in research targeting colon cancer and inflammatory conditions. -
Antibacterial Agent
Antibacterial Agent 69 is a novel antimicrobial compound that targets and inhibits the growth of multidrug-resistant bacteria. With a reported minimum inhibitory concentration (MIC) of 2.978 μM, it demonstrates significant antibacterial activity. This agent is primarily employed in research focused on combating antibiotic resistance and developing new therapeutic strategies against challenging bacterial infections.
