1-Methyl-4-nitroimidazole

Catalog No.: A27434
Antibacterial Agent
1-Methyl-4-nitroimidazole is an antibacterial agent that functions primarily through reduction by bacterial nitroreductases, leading to the generation of toxic derivatives. These derivatives induce DNA damage and inhibit bacterial nucleic acid synthesis, while also producing toxic superoxides that promote bacterial cell death. This compound demonstrates moderate in vitro activity against both bacterial and fungal pathogens and is applicable in research focused on skin infections, purulent infections, and urinary tract infections.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1-Methyl-4-nitroimidazole is an antibacterial agent that functions primarily through reduction by bacterial nitroreductases, leading to the generation of toxic derivatives. These derivatives induce DNA damage and inhibit bacterial nucleic acid synthesis, while also producing toxic superoxides that promote bacterial cell death. This compound demonstrates moderate in vitro activity against both bacterial and fungal pathogens and is applicable in research focused on skin infections, purulent infections, and urinary tract infections.
Product Information
Catalog NumA27434
FormulaC4H5N3O2
Molecular Weight127.10
CAS Number3034-41-1
SMILESCN1C=NC([N+]([O-])=O)=C1
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