Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Antibacterial Agent 69 is a novel antimicrobial compound that targets and inhibits the growth of multidrug-resistant bacteria. With a reported minimum inhibitory concentration (MIC) of 2.978 μM, it demonstrates significant antibacterial activity. This agent is primarily employed in research focused on combating antibiotic resistance and developing new therapeutic strategies against challenging bacterial infections. -
Anti-inflammatory/Antioxidant/Antibacterial Agent
Eukovoside is a cinnamic acid derivative that primarily exerts anti-inflammatory, antioxidant, and antibacterial effects. This compound shows potential in the study of hyperglycemic diseases and is useful for investigating various inflammatory conditions, including eye inflammation and respiratory tract disorders. Additionally, Eukovoside may contribute to research focused on allergic responses such as hay fever and conjunctivitis, as well as infections like colds, influenza, and sinusitis. -
Bacterial Inhibitor
Ceftiofur is a cell wall synthesis inhibitor targeting bacterial penicillin-binding proteins (PBPs). It demonstrates bactericidal activity by interfering with the peptidoglycan synthesis in bacterial cell walls, resulting in cell lysis. Additionally, Ceftiofur exhibits anti-inflammatory properties by inhibiting the activation of NF-κB and MAPKs, which decreases the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. This makes Ceftiofur a valuable reagent in research investigating bacterial infections and inflammation processes. -
Bacterial Quorum-sensing Signaling Molecule
N-3-oxo-dodecanoyl-L-homoserine lactone is a bacterial quorum-sensing signaling molecule primarily associated with Pseudomonas aeruginosa and Burkholderia cepacia complex. This compound plays a critical role in bacterial communication, regulating gene expression in response to changes in cell density. Additionally, N-3-oxo-dodecanoyl-L-homoserine lactone has been shown to induce interleukin-8 (IL-8) production in human bronchial epithelial cells, making it valuable for research in host-pathogen interactions and inflammatory responses. -
Bacterial Inhibitor
Aeroplysinin 1 is a secondary metabolite with a primary target as a bacterial inhibitor. It exhibits significant antibiotic activity against Gram-positive bacteria and demonstrates antiviral efficacy against HIV-1, with an IC50 of 14.6 μM. Additionally, Aeroplysinin 1 possesses anti-inflammatory, anti-angiogenic, and anti-tumor properties, and has been shown to induce apoptosis in endothelial cells. This compound is valuable for research applications in microbiology, virology, and cancer studies. -
Antibacterial Growth Promoter
Nitrovin hydrochloride is an antibacterial growth promoter that targets thioredoxin reductase 1 (TrxR1) to induce reactive oxygen species (ROS)-mediated cell death. This compound exhibits both non-apoptotic and apoptotic-like mechanisms of action. It also demonstrates anticancer activity, with IC50 values ranging from 1.31 to 6.60 μM in various tumor and normal cell lines, making it a valuable tool for cancer research and therapeutic development. -
Bacterial/Fungal Inhibitor, Preservative Agent
Methylisothiazolinone hydrochloride is a bacterial and fungal inhibitor, primarily functioning as a preservative agent. It activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and an inflammatory response. Research indicates that it may promote the development of atopic dermatitis in murine models by disrupting Th2/Th17 immune responses. Additionally, Methylisothiazolinone hydrochloride has been shown to cause mitochondrial damage in the endothelium of rat cerebral blood vessels, highlighting its cellular impact. -
Bacterial Inhibitor
K-252c is a staurosporine analog that selectively inhibits protein kinase C (PKC), exhibiting an IC50 value of 2.45 µM. This compound is known for its ability to induce apoptosis in human chronic myelogenous leukemia cells, making it a valuable tool in cancer research. Additionally, K-252c demonstrates inhibitory effects on β-lactamase, chymotrypsin, and malate dehydrogenase, further expanding its utility in studying bacterial resistance and enzyme activity. -
Antibacterial Agent
Lasalocid is an antibacterial and anticoccidial agent that functions as a feed additive in agricultural applications. It has demonstrated antitumor activity, suggesting potential utility in oncological research. Additionally, Lasalocid is orally bioactive, making it suitable for studies involving gastrointestinal absorption and pharmacokinetics. -
Bacterial Agent And Polyamine Transport System Inhibitor
AMXT-1501 is an antibacterial agent and polyamine transport system inhibitor that targets membrane phospholipids. It exhibits significant antibacterial activity against a range of multidrug-resistant Gram-positive and Gram-negative bacteria, specifically inhibiting capsular biosynthesis in Streptococcus pneumoniae. Additionally, AMXT-1501 interferes with ornithine decarboxylase and polyamine pathways, leading to the inhibition of neuroblastoma cell proliferation. Research applications include studies on multidrug-resistant bacterial infections, pneumococcal infections, and neuroblastoma therapeutics. -
Antibacterial Agent
Lasalocid sodium is an antibacterial and anticoccidial agent primarily utilized in veterinary medicine as a feed additive. This compound exhibits significant antitumor activity, demonstrating potential for additional therapeutic applications. Its oral bioactivity further enhances its utility in various research studies focused on microbial resistance and cancer biology. -
Antibacterial Agent
Deoxyshikonin is an antibacterial agent that exhibits significant activity against methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) of 17 μg/mL. It enhances the expression of VEGF-C and VEGF-A mRNA in human microvascular endothelial cells, promotes the interaction of HIF-1α and HIF-1β subunits, and binds to specific DNA sequences associated with HIF. Additionally, Deoxyshikonin demonstrates proangiogenic and antitumor effects by inhibiting colorectal cancer via the PI3K/Akt/mTOR signaling pathway, making it valuable for both antibacterial and cancer research applications. -
Bacterial Inhibitor
Vasicine, a quinazoline alkaloid derived from Justicia adhatoda, primarily targets bacterial strains as an inhibitor. This compound is known to activate the PI3K/Akt signaling pathway and demonstrates significant antioxidant and anti-inflammatory activities. Its unique biological profile makes Vasicine valuable for research in microbial resistance and inflammation-related studies. -
Bacterial Inhibitor
Vasicine hydrochloride, a quinazoline alkaloid derived from Justicia adhatoda, acts primarily as a bacterial inhibitor. It activates the PI3K/Akt signaling pathway and demonstrates significant antioxidant and anti-inflammatory properties. This compound is valuable for research involving antimicrobial activity and cellular signaling pathways, making it a useful tool for studies in infectious disease and inflammation. -
Antibacterial Agent
Canthin-6-one is an indole alkaloid that serves as an effective antibacterial agent. Its primary mechanism involves the inhibition of bacterial growth, making it valuable for research in antimicrobial applications. Additionally, Canthin-6-one exhibits anti-inflammatory properties, suggesting potential in studies related to inflammation. -
Bacterial Inhibitor
Bavachalcone is a bacterial inhibitor known for its multifaceted biological activities. It induces apoptosis and enhances autophagy in HepG2 cancer cells, contributing to its anticancer potential. Additionally, Bavachalcone demonstrates anti-neuroinflammatory and antidepressant effects through modulation of the NF-κB pathway. It also inhibits osteoclast differentiation by interfering with ERK and Akt signaling pathways, as well as the expression of c-Fos and NFATc1, and shows a significant inhibitory effect on BACE-1 activity in vitro. -
Antibacterial Agent
Desfuroylceftiofur is an antibacterial agent and the predominant microbiologically active metabolite of ceftiofur, retaining an intact β-lactam ring. This compound exhibits in vitro activity against a range of Gram-negative and Gram-positive veterinary pathogens, including common equine pathogens. Desfuroylceftiofur is suitable for research applications focused on respiratory infections in veterinary medicine. -
Bacterial Inhibitor
Lysozyme, also known as Muramidase, is a conserved antimicrobial protein that targets bacterial cell wall peptidoglycan (PG). It exerts a bactericidal effect by hydrolyzing PG, thereby limiting bacterial growth on mucosal surfaces and controlling potential pathogens while preventing dysbiosis through microbiota regulation. Additionally, extracellular lysozyme degrades polymeric PG into soluble fragments, activating NOD receptors in mucosal epithelial cells and stimulating the secretion of chemokines and activating factors by neutrophils and macrophages. This makes lysozyme a valuable reagent for studies involving antimicrobial activity, immune response, and microbiome research. -
Bacterial Inhibitor
Ciclopirox olamine is a synthetic antifungal agent primarily targeting various fungal pathogens. It exhibits a broad spectrum of activity against dermatophytes, yeasts, molds, and multiple Gram-positive and Gram-negative bacteria. In addition to its antibacterial properties, Ciclopirox olamine has demonstrated anticancer and anti-inflammatory effects, making it a valuable reagent for research in superficial mycoses, cancer biology, and inflammation studies. -
Antibacterial Preservative
Imidazolidinyl urea functions as an antibacterial preservative by releasing formaldehyde through its decomposition. It exhibits broad-spectrum antibacterial activity, effectively inhibiting the growth of both gram-negative and gram-positive bacteria, as well as limiting yeast and mold proliferation. Additionally, it can be utilized in the formulation of multifunctional hydrogels for managing infectious wounds. Notably, Imidazolidinyl urea may also induce non-histaminergic allergic responses via the activation of MRGPRX2 in mast cells. -
Antibacterial Agent
Ornidazole is a nitroimidazole derivative primarily used as an antibacterial agent. It demonstrates anti-trichomonad activity and is effective against a range of anaerobic bacteria in vitro. Additionally, Ornidazole inhibits the Sonic hedgehog (Shh) signaling pathway and exhibits antitumor properties, making it a valuable tool in the investigation of conditions such as Crohn’s disease. -
Bacterial Inhibitor
X-Neu5Ac sodium is a neuraminidase substrate that facilitates the chromogenic assay of neuraminidase activity in bacterial expression systems. This compound has a Km value of 0.89 mM for neuraminidase, making it an effective tool for studying neuraminidase function and inhibition. Its use in research applications provides insights into bacterial mechanisms and potential therapeutic targets for bacterial infections. -
Antibacterial Agent
Domiphen bromide is a cationic quaternary ammonium salt primarily known for its antibacterial activity. It exhibits potent inhibition of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, and various bacterial phosphatases, making it versatile for medicinal applications. Due to its antibacterial and antimalarial properties, Domiphen bromide is utilized as a preservative and disinfectant and serves as a research tool in the study of bacterial infections such as pharyngitis, thrush, and oral ulcers. -
Bacterial Inhibitor
Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic that primarily targets bacterial growth by inhibiting dihydropteroate synthase and disrupting folate synthesis. This compound exhibits significant antibacterial activity and is primarily utilized in research applications focused on understanding bacterial infections and exploring antibiotic resistance mechanisms. Suitable for studies related to dermatological conditions, it aids in exploring therapeutic strategies for diseases like dermatitis herpetiformis. -
Bacterial Inhibitor
Enoxacin hydrate, a fluoroquinolone antibiotic, targets bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication with IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. This compound exhibits significant antibacterial activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin hydrate functions as an activator of miRNA processing, facilitating siRNA-mediated mRNA degradation and enhancing the biogenesis of endogenous miRNAs. Its unique mode of action also includes the inhibition of cancer cell growth through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing. -
Bacterial Inhibitor
Chlorprothixene hydrochloride functions as an antagonist of dopamine and histamine receptors, exhibiting Kis of 18 nM for hD1, 2.96 nM for hD2, 4.56 nM for hD3, 9 nM for hD5, and 3.75 nM for hH1 receptors. This compound demonstrates significant antipsychotic activity, making it a valuable tool for research into neuropharmacology and the mechanisms underlying psychotic disorders. Its receptor modulation also indicates potential applications in the study of bacterial inhibition mechanisms, providing insights into the interplay between neurotransmitter systems and microbial pathogenesis. -
Bacterial Inhibitor
Bafilomycin B1 is a macrolide antibiotic that targets vacuolar H+-ATPases (V-ATPases). It exhibits neuroprotective properties against Chloroquine-induced cell death and can significantly inhibit the accumulation of lipid droplets induced by oxidized low-density lipoprotein (LDL). Bafilomycin B1 is valuable for research focused on bacterial inhibition and studying lipid metabolism and cellular stress responses. -
Antibacterial Agent
L18-MDP is a derivative of muramyl dipeptide, functioning primarily as an antibacterial agent. It exhibits significant antibacterial activity, making it a valuable candidate for research in the treatment of bacterial and fungal infections. Its mechanism of action involves immune system stimulation, potentially enhancing host defense responses against microbial pathogens. -
Bacterial Inhibitor
Robinetin, a naturally occurring flavonoid, primarily acts as a bacterial inhibitor. This compound exhibits diverse biological activities, including antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant properties. Additionally, Robinetin has demonstrated the ability to inhibit lipid peroxidation and protein glycosylation, making it valuable for various research applications in microbiology and biochemistry. -
Bacterial Inhibitor
Tricyclazole is a pentaketone compound that acts as a bacterial inhibitor primarily by disrupting melanin biosynthesis in fungi. This unique fungicide is effective in controlling rice blast disease by altering the structure and function of fungal cell walls, thereby reducing pathogenicity and penetration. Tricyclazole’s mechanism of action also highlights its potential for studying fungal biology and the effects of melanin on fungal virulence. -
Anti-bacterial/fungal Agent
Eugenol acetate is an antibacterial and antifungal agent that targets multiple biological pathways. It exhibits significant anti-inflammatory and antioxidant properties, acting through the inhibition of NF-κB while enhancing the expression of tumor suppressor proteins such as p53 and p21 (WAF1). Eugenol acetate is also implicated in cancer research, demonstrating the ability to prevent chemically induced skin cancer, inhibit cancer cell proliferation, and induce apoptosis in various cancer cell lines. Its diverse biological activities make it a valuable tool in chemical and biomedical research applications. -
Bacterial/Fungal Inhibitor
2-Methoxybenzaldehyde, also known as o-Anisaldehyde, serves as a bacterial and fungal inhibitor, with a BA50 value of 0.19 against Salmonella. This compound is utilized in the investigation of bacterial and fungal infectious diseases, providing insights into their mechanisms and potential therapeutics. Its effectiveness in hindering microbial growth makes it a valuable reagent for microbiological research. -
Antibacterial Agent
Germacrene D is an antibacterial agent derived from Solidago canadensis. It exhibits significant antibacterial and antifungal activities, demonstrating potential as an adjuvant in enhancing the efficacy of aminoglycosides and azoles. This compound is valuable for research applications focused on combating microbial infections and exploring synergistic effects in antimicrobial therapies. -
Antibacterial Agent
GI261520A functions as an antibacterial agent primarily by inhibiting the PhoQ phosphorylation pathway. This compound exhibits a dose-dependent suppression of PhoP/PhoQ activity and demonstrates an IC50 value of 3.2 μM in inhibiting pagC reporter expression levels. Additionally, GI261520A effectively reduces PhoQc autokinase activity by 80%, allowing it to penetrate eukaryotic cell membranes and target intravacuolar Salmonella, thereby preventing intramacrophage proliferation. It serves as a valuable tool for research into antibacterial mechanisms and intracellular bacterial behavior. -
Bacterial Inhibitor
Enoxacin is a fluoroquinolone antibacterial that primarily targets bacterial DNA gyrase and topoisomerase IV, with reported IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. It exhibits strong inhibitory activity against both gram-positive and gram-negative bacteria. Additionally, Enoxacin acts as a miRNA processing activator, facilitating siRNA-mediated mRNA degradation and promoting the biogenesis of endogenous miRNAs. Notably, Enoxacin serves as a cancer-specific growth inhibitor through the enhancement of TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing, making it valuable for research in bacterial inhibition and cancer biology. -
Bacterial Inhibitor
Roxithromycin is a semi-synthetic macrolide antibiotic that exerts its antibacterial effects by inhibiting protein biosynthesis at the elongation step through binding to the 50S subunit of the bacterial ribosome. This compound demonstrates broad biological activity, including antimicrobial, antiproliferative, and anti-inflammatory properties. Additionally, Roxithromycin has been shown to inhibit tumor vasculature and alleviate lung injury, making it a valuable reagent for research applications in infectious disease, cancer therapy, and respiratory health. -
Antibacterial/Anticancer Agent
Usnic acid is a secondary metabolite derived from lichens, exhibiting significant antibacterial and anticancer properties. It functions primarily by inhibiting DNA and RNA synthesis, leading to cell cycle arrest and apoptosis in various cancer cell lines. Additionally, usnic acid suppresses RANKL-mediated osteoclast formation and function through downregulation of NFATc1. Its antioxidant and anti-inflammatory effects are attributed to the inhibition of lipid peroxidation and myeloperoxidase activity, making it a valuable reagent for diverse biological research applications. -
Antioxidant/Antibacterial/Anticancer Agent
Carvacrol is a monoterpenic phenol that functions as an antioxidant, antibacterial, and anticancer agent. It has demonstrated the ability to cause cell cycle arrest in the G0/G1 phase, downregulate Notch-1 and Jagged-1, and induce apoptosis in cancerous cells. Carvacrol is frequently utilized in research to investigate its therapeutic effects in various biological systems, alongside its applications in food preservation and cosmetic formulations due to its flavoring and fragrance properties. -
Bacterial Inhibitor
Benzoic acid is an aromatic carboxylic acid that functions as a bacterial inhibitor. It demonstrates significant antimicrobial activity by inhibiting the growth of bacteria and fungi, making it an effective preservative. Benzoic acid is widely utilized in food, beverages, cosmetics, and various research applications to study microbial growth inhibition and preservation techniques. -
Bacterial Inhibitor
Tilmicosin is a macrolide antibiotic and calcium channel antagonist that targets the bacterial ribosome's 50S subunit, effectively inhibiting protein synthesis. It possesses significant antimicrobial activity and is primarily utilized in treating respiratory diseases in livestock, including cattle, sheep, and pigs. Additionally, Tilmicosin exhibits immunomodulatory and anti-inflammatory properties, making it a valuable reagent in veterinary medicine research. -
Antibacterial Agent
Tilmicosin phosphate is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes, effectively inhibiting protein synthesis. This compound exhibits antibacterial properties, making it particularly useful for treating respiratory infections in livestock, including cattle, sheep, and pigs. Additionally, Tilmicosin phosphate demonstrates immunomodulatory and anti-inflammatory activities that may enhance its therapeutic efficacy in veterinary applications. -
Antibacterial Agent
Chlorhexidine diacetate is a cationic antimicrobial agent that primarily targets microbial cell membranes. Its mechanism involves non-specific binding to membrane phospholipids, leading to structural disruption and leakage of cellular contents. Chlorhexidine diacetate exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria, making it valuable for applications in microbiology and infection control. Additionally, it can adversely affect membrane permeability, resulting in protein precipitation and metabolic disturbances, which contribute to rapid microbial growth inhibition and induction of cell death. -
Antibacterial Agent
5,7-Dihydroxy-4-methylcoumarin is a coumarin derivative known for its antibacterial properties. This compound exhibits significant antifungal and antibacterial activities, making it valuable for research in microbial inhibition. Its potential applications include studying mechanisms of action against various pathogens and developing new antimicrobial agents. -
Antibacterial Agent
D-Gluconic acid calcium hydrate is a carboxylic acid known for its antibacterial and chelating properties. It plays a significant role in inhibiting bacterial growth and is commonly used in various biomedical and pharmaceutical research applications. Its ability to complex with metal ions makes it valuable for studies involving metal ion regulation and antimicrobial effectiveness. -
Bacterial Inhibitor
Sodium citrate dihydrate is a bacterial inhibitor that acts by disrupting cellular processes in bacteria. This compound exhibits antibacterial, anti-tumor, and antioxidant activities, demonstrating potential in both microbial and cancer research applications. It can be utilized as a cosolvent or buffer in various biochemical assays, facilitating enhanced stability and solubility of target compounds. -
Anti-Bacterial Agent
Cephemimycin is an antibacterial agent that exhibits modest activity against bacterial and fungal pathogens. This compound is primarily utilized in research focused on antimicrobial resistance and the development of new antibiotic therapies. Its spectrum of activity may provide insights into the mechanisms of bacterial inhibition and inform further studies in pharmacology and microbiology. -
Anti-Bacterial/Fungal Agent
Aspochalasin A is an anti-bacterial and anti-fungal agent that targets microbial cell wall synthesis. It demonstrates significant inhibitory activity against a range of pathogenic bacteria and fungi, making it a valuable tool in the study of antimicrobial resistance. Research applications include examining its efficacy in infection models and investigating potential therapeutic uses in treating bacterial and fungal infections. -
Anti-Bacterial/Fungal Agent
Clavalanine is an anti-bacterial and anti-fungal agent that specifically inhibits a range of bacterial and fungal strains. Its mechanism of action involves disruption of microbial cell wall synthesis, leading to cell lysis and death. Clavalanine is utilized in research applications focused on investigating and combating infectious diseases caused by resistant microbial strains. -
Antibacterial Agent
(9Z)-9,17-Octadecadiene-12,14-diyne-1,11,16-triol is a natural product primarily recognized for its antibacterial properties. It exhibits significant activity against Bacillus subtilis and Pseudomonas fluorescens, as well as antifungal activity against Cladosporium cucumerinum and molluscicidal effects on Biomphalaria glabrata. Additionally, this compound serves as a valuable click chemistry reagent due to its alkyne functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating diverse applications in chemical biology and pharmaceutical research. -
Antibacterial Agent
SMTP-0 (ent-Stachybotrin B) is an antibacterial agent derived from Stachybotrys microspora. While it is an enantiomer of Stachybotrin B and a member of the SMTP family, it does not exhibit plasminogen modulation activity. SMTP-0 demonstrates notable antibacterial and antifungal properties, making it a valuable tool for research into infectious diseases.
