Domiphen bromide is a cationic quaternary ammonium salt primarily known for its antibacterial activity. It exhibits potent inhibition of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, and various bacterial phosphatases, making it versatile for medicinal applications. Due to its antibacterial and antimalarial properties, Domiphen bromide is utilized as a preservative and disinfectant and serves as a research tool in the study of bacterial infections such as pharyngitis, thrush, and oral ulcers.
Domiphen bromide is a cationic quaternary ammonium salt primarily known for its antibacterial activity. It exhibits potent inhibition of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, and various bacterial phosphatases, making it versatile for medicinal applications. Due to its antibacterial and antimalarial properties, Domiphen bromide is utilized as a preservative and disinfectant and serves as a research tool in the study of bacterial infections such as pharyngitis, thrush, and oral ulcers.
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