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OV-1, sheep

Catalog No.: A49519
Bacterial Inhibitor
OV-1, sheep is an alpha-helical antimicrobial peptide derived from the SMAP29 peptide of sheep, specifically designed to target and inhibit a range of antibiotic-resistant bacterial strains. This compound demonstrates significant efficacy against both mucoid and nonmucoid strains of Pseudomonas aeruginosa. OV-1, sheep is a valuable tool for research applications focusing on antimicrobial resistance and the development of peptide-based therapeutics.
OV-1, sheep 326855-45-2 Bacterial Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOV-1, sheep is an alpha-helical antimicrobial peptide derived from the SMAP29 peptide of sheep, specifically designed to target and inhibit a range of antibiotic-resistant bacterial strains. This compound demonstrates significant efficacy against both mucoid and nonmucoid strains of Pseudomonas aeruginosa. OV-1, sheep is a valuable tool for research applications focusing on antimicrobial resistance and the development of peptide-based therapeutics.
Product Information
Catalog NumA49519
FormulaC105H188N34O21
Molecular Weight2262.83
CAS Number326855-45-2
SequenceLys-Asn-Leu-Arg-Arg-Ile-Ile-Arg-Lys-Ile-Ile-His-Ile-Ile-Lys-Lys-Tyr-Gly
Sequence shorteningKNLRRIIRKIIHIIKKYG
SMILES[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(NCC(O)=O)=O)=O)CCCCN)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CC(N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O
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Microbiology > Antifection > Bacterial