Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
T145 is an oxazolidinone antibacterial agent that demonstrates potent inhibitory activity against a range of Gram-negative bacteria, including Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter cloacae. It also targets Gram-positive organisms such as Enterococcus faecalis and Staphylococcus aureus, as well as acid-fast pathogens like Mycobacterium abscessus, Mycobacterium avium, and Mycobacterium tuberculosis. This compound is useful in the development of new strategies to combat multi-drug resistant bacterial infections. -
Anti-Bacterial Agent
Nocardicin B is a natural antibacterial agent derived from Nocardia uniformis subsp. tsugamanensis. It exhibits selective antibacterial properties, demonstrating effectiveness primarily against specific Gram-negative bacteria such as Proteus species and axillary bacillus. Research applications include studying its mechanism of action and potential therapeutic roles in combating bacterial infections. -
Anti-Bacterial Agent
Midecamycin A2 is a macrolide antibiotic that exerts its primary antibacterial action against Gram-positive bacteria, demonstrating significant efficacy while showing limited activity against Gram-negative bacteria, mycobacteria, and fungi. This compound is valuable for research applications focusing on the mechanisms of antibiotic resistance, bacterial pathogenesis, and the development of new antimicrobial agents. Its unique profile positions it as a useful reagent in studies involving bacterial infections and treatment strategies. -
Bacterial Metabolite
Leucanicidin is a macrolide bacterial metabolite that targets various pathogenic larvae. Demonstrating significant toxicity, it effectively affects L. separata fourth instar larvae at a concentration of 20 ppm, as well as H. contortus, T. colubriformis, and O. circumcincta larvae, with LD50 values ranging from 0.23 to 0.42 μg/mL. This compound is applicable in research exploring biological pest control and the development of antimicrobial agents. -
Antibacterial Agent
FK 089 is an antibacterial agent that targets bacterial cell function. It exhibits significant antimicrobial activity, making it valuable for research into infection mechanisms and potential therapies. This compound is particularly useful for studies investigating bacterial resistance and the development of new antibacterial strategies. -
Antimycobacterial Agent
Antibacterial Agent 328 is an enoyl-ACP reductase (InhA) inhibitor targeting mycolic acid biosynthesis in Mycobacterium tuberculosis. This compound demonstrates significant activity against both drug-resistant and drug-susceptible strains of M. tuberculosis. With favorable pharmacokinetic properties and a promising safety-related selectivity index, Antibacterial Agent 328 is a valuable tool for research focused on tuberculosis and related infections. -
Antibacterial Agent
CCR-11 is an antibacterial agent that targets bacterial cell division by inhibiting the assembly of FtsZ. It demonstrates potent activity against B. subtilis with an IC50 value of 1.2 μM and is also effective in inhibiting HeLa cell proliferation at an IC50 of 18.1 μM. CCR-11 is a valuable reagent for research focused on FtsZ-targeted antibacterial strategies and the mechanistic understanding of bacterial cytokinesis. -
Anti-Bacterial Agent
6-Deoxyparomomycin is a glycoside antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. Derived from the strain of Streptomyces rimosus forma paromomycinus, it exhibits significant antibacterial activity against a range of Gram-positive and Gram-negative bacteria. This compound is of interest for research into antibiotic mechanisms and the development of novel antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 300 ((S)-3-[4-(Methylthio)phenyl]-2-oxo-5-(aminomethyl)-oxazolidine) is a potent antibacterial compound targeting bacterial protein synthesis. This aminomethyl oxooxazolidinyl benzene derivative exhibits significant antimicrobial activity, making it a valuable tool for research in microbiology and pharmacology. It can be utilized in studies focused on developing new antibacterial therapies and understanding antibiotic resistance mechanisms. -
Bacterial Inhibitor
Timcodar mesylate is a bacterial efflux pump inhibitor that targets multidrug-resistant strains by directly inhibiting ethidium bromide efflux in Staphylococcus aureus. This compound enhances the effectiveness of antibiotic treatments by reducing the minimum inhibitory concentration required against Gram-positive pathogens, including Staphylococcus aureus, Enterococcus, and Streptococcus pneumoniae. Timcodar mesylate serves as a valuable tool in microbial resistance studies and antibiotic synergy research. -
Bacterial
Novobiocic acid is the aglycone form of the antibiotic Novobiocin, targeting bacterial DNA gyrase. This compound exhibits potent antibacterial activity by inhibiting the ATPase activity of the enzyme, thereby disrupting bacterial DNA replication and transcription. Novobiocic acid is widely utilized in microbial research to study antibiotic resistance mechanisms and to evaluate new antibacterial agents. -
Bacterial Inhibitor
Anti-MRSA agent 24 is a potent antimicrobial compound specifically targeting methicillin-resistant Staphylococcus aureus (MRSA), with particular efficacy against penicillin-resistant strains. This reagent demonstrates significant antibacterial activity, making it essential for research applications focused on combating resistant bacterial infections and studying mechanisms of antibiotic resistance. -
Bacterial Inhibitor
Streptovitacin A is a potent antibacterial agent derived from microorganisms, designed to inhibit a wide range of bacterial strains and demonstrate antiproliferative effects on tumor cells. Its primary mechanism involves interference with essential bacterial processes, making it a valuable tool in microbiological research and cancer studies. Researchers can utilize Streptovitacin A to explore bacterial resistance mechanisms and evaluate its therapeutic potential in oncology. -
Anti-Bacterial Agent
Chloropolysporin C is an antibacterial agent with potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus species. Its efficacy in inhibiting these pathogens makes it a valuable tool for research related to bacterial resistance and the development of new antimicrobial therapies. Chloropolysporin C is particularly useful in studies focused on combating antibiotic-resistant infections. -
Antibacterial Agent
6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone is an antibacterial agent that exhibits significant activity against Escherichia coli and Staphylococcus epidermidis, with a minimum inhibitory concentration (MIC) of 10 μg/mL. This compound can be isolated from the plant species Piper obliquum and may serve as a valuable tool for research into antibacterial mechanisms and potential therapeutic applications. -
Anti-Bacterial Agent
Coriolin A is an anti-bacterial agent that demonstrates significant inhibitory activity against Gram-positive bacteria, with some effectiveness against Gram-negative bacteria and yeast, as well as the protozoan Trichomonas vaginalis. At a concentration of 5 μg/mL, it has been shown to inhibit the growth of Yoshida sarcoma by 61.6%. However, Coriolin A does not exhibit inhibitory effects on Ehrlich ascites carcinoma in animal models. Its diverse biological activities make it a valuable reagent for research in antimicrobial therapies and cancer studies. -
Anti-Bacterial Agent
Norplicacetin is an anti-bacterial agent primarily targeting Gram-positive bacteria and mycobacteria. Isolated from Str. plicatus NCIB 11305, it exhibits significant antimicrobial activity, making it a valuable reagent for research into bacterial infections. Its effectiveness against resistant strains can be pivotal in studies aimed at developing new therapeutic strategies in infectious disease management. -
Antibacterial/Antitumor Agent
10-Thiofolic acid is an effective antibacterial and antitumor agent that functions by targeting folate metabolism. This compound demonstrates significant inhibitory activity against Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 7469). Its properties make 10-Thiofolic acid a valuable tool for research focused on leukemia and other related oncological pathways. -
Anti-Bacterial Agent
Amicoumacin C is an anti-bacterial agent that demonstrates moderate activity against various bacterial strains. While its pharmacological effects may be limited, it serves as a valuable tool for research in microbial studies and the development of antibacterial agents. This compound can assist in exploring mechanisms of bacterial resistance and contribute to the identification of new therapeutic targets. -
Anti-Bacterial Agent
Antibiotic U 44590 primarily targets bacterial pathogens as an anti-bacterial agent. It exhibits effective activity against Gram-positive and Gram-negative bacteria, as well as DNA viruses. This compound is valuable for research applications focusing on bacterial resistance mechanisms and the development of novel antibacterial therapies. -
Anti-Bacterial Agent
Saframycin H is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits potent inhibitory activity against mouse lymphocyte L-1210 cells, with an ID50 value of 0.033 μM. This compound is valuable for research applications exploring bacterial infections and immune response mechanisms. -
Antibacterial Agent
IMB-H4 is an antibacterial agent that specifically targets BamA, disrupting the interaction between BamA and BamD. This compound demonstrates significant growth inhibition against various bacterial strains, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. IMB-H4 serves as a valuable tool for research focused on bacterial resistance and the development of novel antibacterial strategies. -
Anti-Bacterial Agent
Elloramycin is an anti-bacterial agent that exhibits weak activity against Gram-positive bacteria and certain leukemic cells, specifically L-1210. Additionally, it demonstrates significant inhibition of Streptomyces activity, including the suppression of their own production. However, it has no effect on mouse leukemic P388 cells in vivo. This compound is relevant for research exploring bacterial inhibition and leukemia treatment alternatives. -
Anti-Bacterial Agent
Senfolomycin A is an anti-bacterial agent that exhibits activity against Gram-positive bacteria and mycobacteria. Notably, it is effective against penicillin-resistant Staphylococcus aureus as well as strains resistant to Streptomycin, Neomycin, and macrolide antibiotics. Senfolomycin A also demonstrates reduced efficacy against Gram-negative bacteria, making it a valuable compound for research in the study of antibiotic resistance and bacterial infections. -
Anti-Bacterial Agent
Leucomycin A6 is an effective anti-bacterial agent targeting Gram-positive bacteria. It exhibits potent antibacterial activity, making it valuable in microbiological research and the study of bacterial infections. Its utility in identifying and characterizing bacterial resistance mechanisms further supports its application in research settings focused on antibiotic efficacy. -
Anti-Bacterial Agent
Cremimycin acts as an anti-bacterial agent with significant activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), demonstrating a minimum inhibitory concentration (MIC) of 0.2-0.39 μg/mL. Additionally, Cremimycin exhibits cytotoxic properties against various mouse tumor cell lines, including P388, L1210, IMC, S180, B16, and SS3 in vitro, making it a valuable compound for cancer research and antibiotic studies. -
Antibacterial Peptide
Plantaricin F is an antibacterial peptide that demonstrates potent inhibitory activity against various gram-negative bacteria, including the foodborne pathogens Salmonella enteritidis and Pseudomonas aeruginosa. Additionally, Plantaricin F effectively targets several species of Lactobacillus, Pediococcus, and Leuconostoc. This reagent is suitable for research applications focused on antibiotic development and the study of antimicrobial peptides. -
Anti-Bacterial Agent
7-O-Isopentenyl-γ-fagarine is an alkaloid derived from Peltostigma guatemalense, known for its antibacterial properties. This compound exhibits significant antimicrobial activity, making it a valuable reagent for research in the development of antibacterial agents and potential therapeutics against various infections. Additionally, it demonstrates antimalarial activities in vitro, contributing to investigations into malaria treatment options. -
Antibacterial Agent
9-Oxonerolidol is a farnesane-type sesquiterpenoid known for its antibacterial properties. Isolated from the plant Chiliadenus lopadusanus, this compound exhibits significant activity against both Gram-positive and Gram-negative bacteria, including strains resistant to conventional antibiotics. It serves as a valuable research tool for studies focused on combating bacterial infections and exploring natural antimicrobial agents. -
Antibacterial Agent
(3R)-7,4’-Dihydrohomoisoflavanone targets bacterial pathogens and exhibits significant antibacterial activity. It has been shown to be effective against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research aimed at developing new antibacterial strategies and understanding the mechanisms of bacterial resistance. -
Antibacterial Inhibitor
HA5 is an antibacterial inhibitor that targets biofilm formation in Streptococcus mutans. It demonstrates a potent inhibitory effect with an IC50 value of 6.42 μM, selectively disrupting biofilm structure without impacting bacterial growth. Additionally, HA5 reduces glucan production and extracellular DNA levels, making it a valuable tool for studying bacterial pathogenesis and potential therapeutic interventions in dental caries research. -
Anti-Neuroinflammatory/Antibacterial Agent
Anti-neuroinflammation agent 2 is an effective anti-neuroinflammatory and antibacterial agent. It exhibits potent inhibition of pro-inflammatory cytokines, with IC50 values of 3.06 µM for TNF-α and 4.31 µM for IL-6. Additionally, it demonstrates antibacterial activity against Gram-positive bacteria, with EC50 values ranging from 0.87 to 3.16 µM. This compound is suitable for research applications targeting neuroinflammatory pathways and microbial infection studies. -
Bacterial Inhibitor
7-O-Methylaloeresin A is a 5-methylchromone glycoside isolated from Commiphora socotrana, acting primarily as a bacterial inhibitor. It demonstrates significant antimicrobial activity against methicillin-resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255), with minimum inhibitory concentrations (MIC) of 0.72 mM and 0.18 mM, respectively. Additionally, 7-O-Methylaloeresin A exhibits antioxidant properties, with IC50 values of 0.026 mM for the DPPH assay and 0.021 mM for the 2-deoxyribose degradation assay, making it useful in studies related to microbial resistance and oxidative stress. -
Antibacterial Agent
Guajaphenone A is a benzophenone glycoside identified as an antibacterial agent, derived from the leaves of Psidium guajava L. It exhibits notable inhibitory effects against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. This compound is valuable for research focused on bacterial infections and the development of antibacterial therapeutics. -
Antibacterial Agent
Antibacterial Agent 261 is a potent inhibitor of peptidomimetic peptide deformylase (PDF), demonstrating IC50 values of 2.5 nM against Staphylococcus aureus and 10.6 nM against Escherichia coli. This compound exhibits significant antibacterial activity, making it a valuable tool for research focused on combating bacterial infections and understanding bacterial resistance mechanisms. Its efficacy against key pathogens highlights its potential applications in drug development and antibacterial studies. -
Antibacterial Agent
Bromamphenicol is a potent antibacterial agent that functions by binding to the 50S ribosomal subunit, thereby inhibiting peptidyl transferase activity and disrupting protein synthesis. This compound demonstrates significant antibacterial activity and is valuable in research applications involving bacterial infections and antibiotic resistance mechanisms. Its effectiveness in targeting bacterial protein synthesis makes it an essential tool for studying antibiotic efficacy and ribosomal function. -
Antibacterial Peptide
Zaloganan is an antibacterial peptide that functions by disrupting bacterial membranes. This compound displays broad-spectrum antibacterial activity against various pathogens, making it useful in research related to antimicrobial resistance and infection control. Its ability to compromise membrane integrity can provide insights into peptide-mediated mechanisms of action and the development of novel therapeutic agents. -
Antibacterial Agent
Antibacterial agent 199 is an activator of caseinolytic protease (ClpP) with a dissociation constant (Kd) of 0.7 μM. This compound demonstrates significant antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae, as well as the Gram-negative bacterium Neisseria meningitidis, with minimum inhibitory concentrations (MICs) of 16 μg/mL, 0.5 μg/mL, and 0.5 μg/mL, respectively. Antibacterial agent 199 is suitable for studies focused on bacterial resistance and the development of novel antimicrobial therapies. -
Bacterial
Acridine-9-carboxaldehyde is a bioactive compound recognized for its antibacterial and antitumor properties. This reagent serves as an essential building block in the synthesis of diverse bioactive derivatives, facilitating compound development in medicinal chemistry. Additionally, Acridine-9-carboxaldehyde demonstrates notable cytotoxic effects against specific cancer cell lines, positioning it as a valuable candidate for research in cancer inhibition. -
Antibacterial Agent
Antibacterial Agent 37 is a potent antibacterial compound derived from patent WO2015063714A1, specifically compound B. This agent exhibits significant activity against a range of bacterial pathogens, making it suitable for the study of bacterial infections and their mechanisms. It provides researchers with a valuable tool for investigating antibacterial properties and developing potential therapeutic strategies. -
Antibacterial Agent
Macrocarpal E is a phloroglucinol dialdehyde diterpene derivative with demonstrated antibacterial properties. Isolated from the leaves of Eucalyptus macrocarpa, it exhibits significant activity against a range of bacterial strains. This compound is valuable for research focused on antibacterial drug development and the investigation of natural product pharmacology. -
Antibacterial Agent
α-Mycolic acid, keto cis is a structural lipid component of the mycobacterial cell wall, serving as a potential antibacterial agent. Isolated from Mycobacterium tuberculosis Canetti, this compound plays a key role in modulating membrane permeability and stability. Its unique properties make it a valuable tool for research focused on mycobacterial infections, particularly those caused by Mycobacterium tuberculosis. -
Anti-Mycobacterial Agent
BM635 hydrochloride is a potent MmpL3 inhibitor recognized for its exceptional anti-mycobacterial activity. It exhibits a MIC50 of 0.08 μM against Mycobacterium tuberculosis H37Rv, demonstrating significant efficacy in inhibiting bacterial growth. This compound also enhances the in vivo exposure compared to its free base form, making it a valuable reagent for research targeting mycobacterial infections. -
Antibacterial Agent
Antibacterial Agent 169 is a pyrrolamide-based inhibitor targeting GyrB and ParE, demonstrating significant antibacterial activity. It effectively inhibits Gyrase and Topo IV in Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L, respectively. This compound is valuable for research applications focused on combating bacterial infections and exploring mechanisms of antibiotic resistance. -
Antibacterial Agent
NU-3 (Bisphosphocin NU-3) is a potent antibacterial agent that targets bacterial DNA and cell wall integrity. It induces DNA condensation and cell wall deformation, leading to impaired bacterial function. NU-3 is suitable for research applications focused on the pathogenicity of Escherichia coli and Pseudomonas aeruginosa, enabling the investigation of mechanisms underlying bacterial infections and potential therapeutic interventions. -
Antibacterial Agent
Antibacterial Agent 83 (compound 17h) acts as a potent antibacterial agent targeting vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). This compound effectively reduces biofilm formation in MRSA and demonstrates promising selectivity against resistant bacterial strains. Additionally, Antibacterial Agent 83 shows metabolic stability in human liver microsomes, making it a valuable candidate for further research in the development of novel antibacterial therapies. -
Antibacterial Agent
BT-33 is a fluorinated macrobicyclic oxepanoprolinamide that functions as a potent antibacterial agent. It exhibits broad-spectrum activity against multidrug-resistant bacterial pathogens, making it a valuable tool for combating infections caused by resistant strains. This compound is particularly useful for research applications aimed at understanding antibacterial mechanisms and developing new therapeutic strategies. -
Anti-Bacterial Agent
11-Hydroxynovobiocin is an anti-bacterial agent that primarily targets Gram-negative bacteria. This compound exhibits potent antibacterial activity, making it suitable for research applications focused on the development of novel antimicrobial therapies. Its efficacy against resistant bacterial strains provides valuable insights into combating bacterial infections. -
Bacterial Inhibitor
1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone is a bacterial inhibitor derived from the genus Garcinia. This compound exhibits significant antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentration (MIC) values of 128 μg/mL and 200 μg/mL, respectively. It serves as a valuable tool in research applications aimed at understanding bacterial resistance and developing new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 32 functions primarily as an antibacterial agent, demonstrating potent activity against E. coli strains with minimum inhibitory concentrations (MIC) of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL for NCTC 13351, M 50, and 7 MP, respectively. This compound is valuable for research applications targeting bacterial infections and can be utilized in studies focused on antibiotic resistance mechanisms and the development of new antibacterial therapies.
