Manumycin E is an anti-bacterial agent primarily targeting Gram-positive bacteria, with notable activity against Escherichia coli. It inhibits RAS Faraday base transfer, demonstrating a cytotoxic effect on human cancer cell lines, specifically HCT-116, with an IC50 of 15.6 μg/mL. Due to its limited efficacy against Gram-negative bacteria and fungi, Manumycin E may be primarily utilized in research focused on Gram-positive infections and cancer biology.
Manumycin E is an anti-bacterial agent primarily targeting Gram-positive bacteria, with notable activity against Escherichia coli. It inhibits RAS Faraday base transfer, demonstrating a cytotoxic effect on human cancer cell lines, specifically HCT-116, with an IC50 of 15.6 μg/mL. Due to its limited efficacy against Gram-negative bacteria and fungi, Manumycin E may be primarily utilized in research focused on Gram-positive infections and cancer biology.
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