Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Urease-IN-1 is a specific urease inhibitor, demonstrated by an IC50 value of 2.21 ± 0.45 µM. This compound is primarily used for research into bacterial inhibition and is relevant for studies investigating the role of urease in microbial metabolism and pathogenesis. Further applications may include exploring its potential in controlling microbial infections associated with urease-producing bacteria. -
Bacterial Inhibitor
CysHHC10 is a synthetic antimicrobial peptide that acts as a bacterial inhibitor by disrupting the integrity of microbial membranes. This compound demonstrates potent antibacterial activity against a range of both Gram-positive and Gram-negative bacteria, with minimum inhibitory concentrations (MIC) of 10.1 mM for E. coli, 20.2 mM for P. aeruginosa, 2.5 mM for S. aureus, and 1.3 mM for S. epidermidis. CysHHC10 is valuable for research applications focused on combating bacterial infections and studying microbial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 88 (Compound 5h) is a highly effective antibacterial agent that targets a range of bacterial strains. It demonstrates minimal inhibitory concentration (MIC) values of ≤0.0156 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE), and Staphylococcus aureus. Additionally, Antibacterial Agent 88 exhibits inhibitory activity against Bacillus subtilis with an MIC of 4 μg/mL. This compound is suitable for research applications focused on bacterial resistance and infection control. -
Bacterial Inhibitor
SCH-538415 is an acyl carrier protein synthase inhibitor that disrupts bacterial cell functions by targeting the AcpS enzyme. It demonstrates significant antibacterial activity, specifically against Staphylococcus aureus, with an IC50 value of 4.19 μM in enzymatic assays. This compound is valuable for research focused on bacterial inhibition mechanisms and the development of new antimicrobial agents. -
Antibacterial Agent
Antimicrobial agent-22 (THI 6c) is a broad-spectrum antibacterial agent that targets multiple pathways within bacterial cells. It exhibits rapid bactericidal activity and demonstrates significant anti-biofilm properties, making it effective in combating bacterial infections. With low cytotoxicity and minimal hemolytic effects, it is suitable for various biological research applications focusing on antimicrobial efficacy and biofilm prevention. -
Bacterial Inhibitor
(±)-Heraclenol is a coumarin compound known for its antibacterial properties. Isolated from the fruits of Angelica lucida, it demonstrates effective inhibition against various bacterial strains. This compound is utilized in research applications focused on understanding bacterial resistance mechanisms and exploring novel antimicrobial agents. -
Antimycobacterial Agent
Tetrahydroxysqualene is a triterpene with demonstrated antimycobacterial activity against Mycobacterium tuberculosis, exhibiting a minimum inhibitory concentration (MIC) of 10.0 μg/mL. This compound can be isolated from the methanolic extracts of Rhus taitensis Guill. Its efficacy makes it a valuable tool for research into possible treatments for tuberculosis and other mycobacterial infections. -
Antibacterial Agent
MC 304 is a β-resorcylate compound derived from the cultures of Phanerochaete chrysosporium, acting primarily as an antibacterial agent. This compound demonstrates significant antibacterial activity, making it valuable for microbiological research. Additionally, MC 304 promotes root elongation in Lepidium sativum, highlighting its potential applications in plant growth studies. -
Anti-bacterial Agent
Kumbicin C is a bis-indolyl benzenoid compound derived from the Australian soil fungus Aspergillus kumbius. This compound primarily functions as an anti-bacterial agent, exhibiting inhibitory effects on the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis. Kumbicin C holds potential applications in antimicrobial research and the development of new therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
E 5065 is an orally active antibacterial agent that targets a broad spectrum of microorganisms. This compound exhibits potent in vitro activity against Gram-negative bacteria, Gram-positive cocci, and anaerobes, with an MIC90 of 0.5 μg/mL against Clostridium spp. E 5065 is effective in providing protection against experimental infections caused by Pseudomonas aeruginosa, making it a valuable tool for research in infectious disease and antibiotic efficacy studies. -
Bacterial Inhibitor
Pyrithione sodium primarily targets bacterial inhibition and exhibits antimicrobial properties. This compound is commonly utilized in research applications related to skin microbiome studies and the development of anti-fungal and anti-bacterial treatments. While it is noted for its effectiveness in inhibiting bacterial growth, its limited skin penetration should be considered in experimental designs. -
Anticancer/Anti-inflammatory/Antibacterial Agent
Aspergillumarin A is a dihydroisocoumarin derivative that primarily targets antitumor and anti-inflammatory pathways. It inhibits cell proliferation by inducing G0/G1 phase arrest in HepG2 hepatocellular carcinoma cells, making it a valuable tool for cancer research, particularly in studies of hepatocellular carcinoma (HCC). Additionally, Aspergillumarin A demonstrates weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis, supporting its potential use in exploring antibacterial applications. -
Bacterial Biofilm Inhibitor
Antibacterial synergist 1 (compound 20P) is an effective bacterial biofilm inhibitor. It specifically inhibits the production of pyocyanin and biofilm formation in Pseudomonas aeruginosa with IC50 values of 8.6 μM and 4.5 μM, respectively. This compound is valuable for researching therapeutic strategies against P. aeruginosa infections, particularly in the context of chronic infections characterized by biofilm development. -
Antibacterial Agent
Cucurbitacin F is a bioactive compound extracted from Hemsleya gigantha, primarily acting as an antibacterial agent. It exhibits significant antibacterial properties, making it a valuable tool for studies focused on bacterial infections. This reagent can aid in the exploration of antimicrobial mechanisms and the development of new therapeutic approaches in combating bacterial pathogens. -
Bacterial Inhibitor
Eupatarone, also known as Caleprunin B, is a bacterial inhibitor derived from Calea platylepis. This compound exhibits significant antibacterial activity, making it a valuable tool in research focused on combating bacterial infections. Its ability to inhibit bacterial growth positions Eupatarone as an important reagent in microbiological studies and drug discovery efforts targeting antibiotic resistance. -
Antibacterial Agent
Antibacterial agent 106 is a potent antibacterial compound targeting multi-drug resistant Gram-positive pathogens. This orally active agent demonstrates significant antibacterial efficacy, achieving a 99.7% clearance of intracellular methicillin-resistant Staphylococcus aureus (MRSA) within macrophages. Additionally, antibacterial agent 106 features an alkyne moiety, facilitating its use as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, offering valuable applications in chemical biology and medicinal research. -
Bacterial Inhibitor
Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide derived from Bombina species, primarily functioning as a bacterial inhibitor. This peptide exhibits potent activity against a range of bacterial strains, making it a valuable tool for research in antimicrobial resistance and the development of new therapeutic agents. Its unique mechanism and efficacy position it as an important candidate for studies focused on infection control and peptide-based drug design. -
Antibacterial Agent
α-Mycolic acid (C80) is a structural lipid of the mycobacterial cell wall, primarily targeting membrane integrity. Isolated from Mycobacterium tuberculosis Canetti, this compound plays a crucial role in modulating membrane permeability and stability. It is valuable for research applications focused on understanding and treating infections caused by Mycobacterium tuberculosis. -
Antibacterial Agent
Antibacterial Agent 44 is a potent antibacterial compound designed to target bacterial pathogens. This agent exhibits significant antibacterial activity, making it suitable for investigating various bacterial infections. Its efficacy in research supports the development of novel therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Antibacterial Agent 103 primarily targets bacterial cells, exhibiting strong antibacterial activity against a wide range of both Gram-positive and Gram-negative bacteria. This reagent is valuable for research involving the inhibition of resistant bacterial strains, making it a critical tool for studies aimed at addressing antibiotic resistance in clinical settings. -
Antibacterial Agent
Antibacterial Agent 79 is a potent antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant activity against both Gram-positive and Gram-negative bacteria, making it a valuable tool for research into antibiotic mechanisms and resistance. This agent is suitable for studies focused on understanding bacterial infections and developing new therapeutic strategies. -
Antibacterial Agent
Rupesin E is a natural antibacterial agent derived from Patrinia rupestris, exhibiting potent activity against Escherichia coli. This compound is valuable for research into antimicrobial strategies and the development of novel antibacterial therapies. Its efficacy in targeting bacterial infections highlights its potential applications in pharmaceutical research and infection control studies. -
Antibacterial Agent
U-97456 is an N-hydroxyacetyl derivative with potent antibacterial properties, specifically targeting Mycobacterium tuberculosis. It demonstrates a minimum inhibitory concentration (MIC) of less than 50 μg/mL against the M. tuberculosis H37Rv strain. This compound is useful for research focused on infectious diseases, particularly in the development of novel antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 98 (Compound G37) is a potent orally active antibacterial compound that primarily targets Gyrase B by inhibiting its ATPase activity. This mechanism disrupts DNA supercoiling in Staphylococcus aureus, effectively exhibiting antibacterial activity. Notably, Antibacterial Agent 98 does not promote the development of resistance in methicillin-resistant S. aureus (MRSA), making it a valuable candidate for research in antimicrobial resistance. -
Bacterial Inhibitor
Antimicrobial agent-21 is a potent bacterial inhibitor that demonstrates significant activity against both gram-positive and gram-negative bacteria. This compound serves as a valuable tool in microbiological research and antibiotic development, aiding in the study of bacterial resistance mechanisms and the efficacy of new antimicrobial strategies. Its broad-spectrum activity makes it applicable in various experimental settings focused on understanding bacterial pathogenesis and treatment. -
Bacterial
MBX-1162 is a bisindole compound that primarily targets bacterial resistance mechanisms. This compound has been studied in relation to Staphylococcus aureus, demonstrating a unique resistance profile without cross-resistance to similar compounds. Research indicates that MBX-1162's activity is associated with the substrate specificity of the MepA and MepR proteins, making it a valuable tool for investigating bacterial resistance and developing novel therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 61 is a potent antibacterial compound targeting specific bacterial pathways. Its primary mechanism involves disruption of bacterial cell wall synthesis, leading to cell lysis and death. This reagent is essential for research applications focused on antibiotic resistance mechanisms and the development of new antibacterial therapies. -
Bacterial Inhibitor
Carbendazim mixture with flusilazole is a potent bacterial inhibitor utilized in the management of sooty mold, particularly attributable to Botrytis narcissicola. This fungicide combination demonstrates efficacy in diminishing lesion size and alleviating secondary sooty mold symptoms, especially when employed alongside other fungicides. In field trials conducted in regions such as Cambridgeshire and Lincolnshire, the application of this mixture significantly controlled sooty mold and enhanced bulb production by employing a strategic spray program that alternated fungicides with varying modes of action. This research emphasizes the importance of selecting appropriate fungicides and methodologies to optimize disease management while minimizing the required applications. -
Antibacterial Agent
Angustifoline hydrochloride is an alkaloid derived from the extract of Lupinus angustifolius L. This compound demonstrates significant antibacterial properties, exhibiting bacteriostatic effects against a range of organisms, including Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Bacillus thuringiensis. Its antimicrobial activity makes it an important reagent for research in the field of antibacterial drug development and microbiology. -
Antibacterial Agent
Antibacterial Agent 154 is a derivative of fluoroquinolones designed to target bacterial strains effectively. It exhibits robust antibacterial activity against both Gram-positive and Gram-negative bacteria. In preclinical studies, Antibacterial Agent 154 displayed significant in vivo efficacy in a mouse model of staphylococcal sepsis, highlighting its potential for further research in antibacterial therapies. -
Antibacterial Agent
Cerastecin D is an antibacterial agent with activity against Acinetobacter baumannii ATCC19606, exhibiting an MITC95 value of 165 nM. This compound is valuable in research focused on bacterial resistance and development of new antimicrobial therapies. Its potential for targeting multi-drug resistant pathogens makes it significant in the field of infectious disease research. -
Bacterial Inhibitor
Cellocidin is a bacterial inhibitor that targets the α-ketoglutarate-succinate system in Xanthomonas species. This agricultural antibiotic demonstrates preventive activity against rice bacterial leaf blight, offering a valuable tool for managing bacterial infections in crop production. Its mechanism of action makes it an essential reagent for research into plant-pathogen interactions and the development of sustainable agricultural practices. -
Bacterial Inhibitor
Phentolamine acetate is a bacterial inhibitor that targets and disrupts the growth of specific bacterial strains, including Staphylococcus aureus. This compound exhibits notable anti-inflammatory and anticancer properties, highlighting its potential for diverse biological applications. Its significant in vitro activity makes it a valuable tool for researchers studying bacterial infections and inflammation-related disorders. -
Antibacterial Agent
Sulfamethomidine is a sulfonamide antibiotic that primarily targets bacterial folic acid synthesis by inhibiting dihydropteroate synthase. This compound exhibits potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria. It is commonly utilized in research applications focusing on antimicrobial efficacy, resistance mechanisms, and the development of combination therapies. -
Antibacterial Agent
7-Phloroeckol is a potent antibacterial agent targeting virulence-associated proteins of Pseudomonas aeruginosa. It demonstrates strong and stable binding to 18 distinct proteins, highlighting its potential in combating bacterial infections. This compound is valuable for research focused on understanding and treating Pseudomonas aeruginosa infections. -
Antibacterial agent
Antibacterial agent 160 is a potent antibacterial compound that disrupts bacterial DNA function, leading to cell death. This reagent effectively eliminates bacterial cells and inhibits biofilm formation, making it a valuable tool for studies on bacterial infections and resistance mechanisms. Its application extends to researching antibacterial efficacy and strategies for combating biofilm-associated infections. -
Antibacterial Agent
Javanicin is an antibacterial agent that targets various pathogenic bacteria, demonstrating activity against Bacillus megaterium, Staphylococcus aureus, Salmonella typhi, and Escherichia coli. Additionally, Javanicin exhibits weak cytotoxicity against the human lung cancer cell line, making it a potential candidate for research into antibacterial and anticancer applications. -
Antibacterial Agent
Antibacterial agent 156 is a potent bactericidal compound that selectively targets cell-wall synthesis in Clostridium difficile. This agent demonstrates significant antibacterial activity, with a minimal inhibitory concentration (MIC) of 0.5 μg/mL against a broad range of strains (MIMIC50 of 101 strains) and an MIC90 of 1 μg/mL. It is an important tool for research applications focused on combating C. difficile infections and studying bacterial cell-wall biosynthesis. -
Antibacterial Agent
Antibacterial Agent 255 is a selective inhibitor of 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE), demonstrating potent antibacterial activity with IC50 values of 13.0 µM for E. coli IspE, 8.0 µM for K. pneumoniae IspE, and 20 µM for A. baumannii IspE. This compound is instrumental in the study of bacterial biosynthesis pathways and can be utilized in antibacterial drug development research. -
Bacterial Inhibitor
Ethionamide hydrochloride is an antituberculosis agent that acts as a bacterial inhibitor. It disrupts mycobacterial cell wall synthesis by inhibiting fatty acid synthesis, leading to potential bacteriostatic or bactericidal effects based on concentration and microorganism susceptibility. Ethionamide hydrochloride forms an adduct with NAD+, which is crucial for its antimicrobial activity. This compound is primarily utilized in research for understanding tuberculosis treatment and the mechanisms of drug resistance in Mycobacterium tuberculosis. -
Antibacterial Agent
5-Hydroxymethyl flucloxacillin is an active metabolite of Flucloxacillin, targeting bacterial infections. This compound demonstrates notable antibacterial activity, making it useful for research applications focused on antimicrobial resistance and bacterial pathogenesis studies. Its efficacy in inhibiting bacterial growth supports investigations into therapeutic strategies for treating infections caused by resistant strains. -
Anti-Bacterial Agent
Saquayamycin C is an anti-bacterial agent with significant antimicrobial activity, though it exhibits a weaker efficacy against Gram-negative bacteria. This compound also demonstrates cytotoxic effects against leukemia P388 cells, including those resistant to Adriamycin. Its applications extend to research in cancer biology and microbial resistance, making it valuable for studies focused on therapeutic development and resistance mechanisms. -
Bacterial Inhibitor
Allergen Gal d 4 (46-61), chicken is a peptide derived from hen egg white lysozyme, exhibiting bacterial inhibitory activity. This compound is utilized in research related to allergenic responses and microbial interactions, making it significant in studies of food allergies and immunological reactions. Its targeted application in bacterial inhibition aids in understanding the role of allergens in various biological systems. -
Antibacterial Agent
Maniladiol is a triterpenoid that serves as an antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 4 mg/mL against the H37Rv strain of M. tuberculosis. This compound is valuable for research focused on tuberculosis infection mechanisms and potential therapeutic applications. -
Antibacterial Agent
8-Desmethyleleutherin is an antibacterial agent derived from the bulbs of Eleutherine americana. It exhibits potent antibacterial activity with minimal inhibitory concentration (MIC) values of 62.5 µg/mL against Staphylococcus aureus strains ATCC27664 and ATCC25923. This compound is valuable for research applications focusing on bacterial resistance and the development of new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 80 is an antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant inhibitory activity against a wide range of gram-positive and gram-negative bacteria. This reagent is valuable for research applications aimed at investigating bacterial resistance mechanisms and developing novel antimicrobial therapies. -
Antibacterial Agent
Xanthoascin is a natural phenolic metabolite that exhibits strong antibacterial activity. Derived from the fermentation products of the endophytic fungus Aspergillus sp. IFB-YXS found in Ginkgo biloba leaves, Xanthoascin demonstrates a minimum inhibitory concentration (MIC) of 0.3125 µg/mL against Clavibacter michiganense subsp. sepedonicus, along with moderate activity against other bacterial pathogens (MIC = 5-20 µg/mL). Its mechanism involves disrupting bacterial cell membrane permeability, resulting in the leakage of nucleic acids. This compound holds potential for research applications in antimicrobial development and the study of plant pathogen interactions. -
Antibacterial Agent
Penamecillin is an acetoxymethyl ester of Penicillin G designed as an orally active antibacterial agent. It acts by inhibiting bacterial cell wall synthesis, rendering it effective against a range of gram-positive bacteria. This compound is primarily utilized in research applications focused on understanding bacterial resistance and the pharmacodynamics of antibiotic treatments. -
Antibacterial Agent
Anti-MRSA agent 8 is a DAPG derivative that exhibits potent antibacterial activity. This compound targets bacterial cell membranes, disrupting their integrity and function. It is particularly valuable for research focused on methicillin-resistant Staphylococcus aureus (MRSA), making it an essential tool for studies on antibiotic resistance and bacterial infection. -
Antibacterial Agent
Antibacterial Agent 57 is an antibacterial compound that exhibits potent activity against a variety of bacterial strains. Its primary mechanism involves the inhibition of bacterial growth, making it a valuable tool for research applications focused on antimicrobial resistance and the development of new therapeutic agents. This compound is essential for studies investigating the efficacy of novel antibacterial therapies and understanding bacterial pathogenesis.
