Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Fungal Agent
Enactin Va is an anti-fungal agent derived from the strain of Streptomyces roseoviridis. It exhibits mild antifungal activity, making it suitable for research applications aimed at exploring antifungal properties and mechanisms of action. This compound can be utilized in studies focused on the development of novel antifungal therapies and the assessment of fungal resistance. -
Antifungal Agent
Cryptosporiopsin A is a polyketide that acts as an antifungal agent, demonstrating significant motility inhibitory and lytic activities against the zoospores of Plasmopara viticola, the pathogen responsible for grapevine downy mildew. This compound is valuable for research applications focused on understanding fungal biology and developing innovative antifungal strategies. -
Antimicrobial Agent
Octacosamicin B is an antimicrobial agent that exhibits activity against yeast and filamentous fungi. While its efficacy against bacteria is limited, it serves as a valuable tool in the study of antifungal mechanisms and the development of new antifungal therapies. This compound is useful in various research applications focused on microbial resistance and antifungal activity. -
Antifungal Antibiotic
Mucidin is an antifungal antibiotic that primarily targets the cytochrome bc1 complex within the mitochondrial respiratory chain, inhibiting electron-transfer reactions. This mechanism disrupts ATP production in fungi, leading to their growth inhibition. Mucidin is useful in research applications focused on fungal pathogenesis and mitochondrial function, providing insights into antifungal resistance and treatment strategies. -
Anti-Fungal Agent
Clavamycin A functions as a potent anti-fungal agent, exhibiting significant activity against Candida species. Its antifungal mechanism is characterized by substantial effectiveness that can be antagonized by the presence of dipeptides or tripeptides, while amino acids do not interfere with its action. Notably, Clavamycin A demonstrates no antibacterial properties and does not inhibit β-lactamase activity. This compound is valuable in studying fungal infections and antifungal resistance mechanisms. -
Antifungal Agent
Amphocil is an equimolar mixture of Amphotericin B and cholesteryl sulfate, serving as a potent antifungal agent. It demonstrates significant antifungal activity, making it particularly relevant for research focused on disseminated cryptococcosis. This formulation enhances the efficacy of Amphotericin B, thereby supporting investigations into treatment strategies for this invasive fungal infection. -
Antifungal Agent
Tetrahydroechinocandin B is a potent antifungal agent that primarily inhibits 1,3-beta-D-glucan synthesis, exhibiting an IC50 value of 0.85 μg/mL. This mechanism of action disrupts fungal cell wall integrity, making it effective against various fungal pathogens. Tetrahydroechinocandin B is commonly utilized in research applications aimed at understanding antifungal mechanisms and developing therapeutic strategies against fungal infections. -
Anti-Fungal Agent
Crocacin B is an anti-fungal agent that exhibits significant activity against both yeast and filamentous fungi. It has been shown to inhibit mouse fibroblast cells (L929), demonstrating its potential cytotoxic effects. Additionally, Crocacin B disrupts the bc1 segment of electron transport in calf heart microsomes, resulting in a redshift of the 569 nm peak in the cytochrome b reduction spectrum. This compound may serve as a valuable tool in fungal research and related applications. -
Antimicrobial Agent
Scorodonin is an antimicrobial agent that exhibits potent antibacterial and antifungal activities, particularly against Streptomyces species. It functions by inhibiting DNA-dependent RNA polymerases, demonstrating an IC50 of 25 μg/mL. This compound may be utilized in research applications focused on microbial resistance, the characterization of RNA polymerase activity, and the development of new antimicrobial agents. -
Anti-Fungal Agent
Neoenactin M2 is an anti-fungal agent that exhibits potent activity against both yeast-like and filamentous fungi. Its mechanism involves disrupting fungal cell membrane integrity, leading to cell death. This compound is valuable for research applications focused on fungal pathogenesis, drug resistance studies, and the development of antifungal therapies. -
Anti-Fungal Agent
Cyclopaldic acid is a potent anti-fungal agent that effectively inhibits spore germination in Garlic botrytis, demonstrating an inhibition rate of 95%-100% at a concentration of 2.5 μg/mL. This compound is valuable for research in fungal biology and plant pathology, providing insights into fungal inhibition mechanisms and potential agricultural applications. -
Phytotoxin
Zinniol is a penta-substituted benzene phytotoxin primarily associated with various phytopathogenic fungi. It has been identified in sunflower tissues during the early stages of infection, suggesting a role in the pathogenesis of sunflower diseases. This compound serves as a valuable tool for research into plant-fungal interactions and the biochemical mechanisms underlying plant diseases. -
Antimicrobial Agent
Darlucin B is an antimicrobial agent exhibiting potent antibacterial and antifungal activity while demonstrating weak cytotoxicity. It is primarily utilized in research applications focused on developing new antimicrobial therapies and understanding microbial resistance mechanisms. Its diverse biological activity makes it a valuable tool in the field of infectious disease research. -
Macrocyclic dilactone
De-N-methylpamamycin-593B is a macrocyclic dilactone characterized by its 16-membered ring structure. This compound exhibits Aerial Mycelium-inducing activity, making it a valuable tool for the study of fungal development and morphology. Its unique properties facilitate research into microbial fermentation processes and the regulation of secondary metabolism in various organisms. -
1,3-β-D-glucan Synthase Inhibitor
L 705589 is an inhibitor of 1,3-β-D-glucan synthase, targeting the synthesis of key structural components in the fungal cell wall. This semi-synthetic penicillin-type antifungal exhibits potent activity against various Candida species, including Candida albicans and Candida glabrata, with minimum fungicidal concentrations ranging from 0.06 to 8 µg/mL. It demonstrates limited efficacy against Cryptococcus neoformans (MFC: 32 - 64 µg/mL) yet maintains effectiveness against drug-resistant Candida strains and shows a reduced tendency to induce resistance. Additionally, L 705589 has been shown to enhance survival rates in models of minor invasive aspergillosis. -
Antifungal Agent
10-Undecenoic acid (copper) serves as an antifungal agent through its diverse mechanisms of action. It inhibits Aβ oligomerization, scavenges reactive oxygen species (ROS), and suppresses μ-calpain activity, contributing to its neuroprotective effects. Additionally, it demonstrates anticancer properties across various tumor types and effectively inhibits biofilm formation by Candida albicans and infections caused by Methicillin-resistant Staphylococcus aureus (MRSA). Furthermore, 10-Undecenoic acid (copper) disrupts quorum sensing signals in Bacillus subtilis and Pseudomonas aeruginosa, making it a valuable reagent for research in fungal infections and cancer biology. -
Secondary Metabolite
Aranorosinol A is a secondary metabolite known for its moderate antibacterial and antifungal activity. This compound is primarily utilized in research applications focused on natural product chemistry and pharmacological screening. Its efficacy against microbial pathogens makes it a valuable candidate for investigating new therapeutic approaches in infectious disease treatments. -
Fungal Inhibitor
Aliconazole is an imidazole derivative that functions as an antifungal agent by inhibiting fungal ergosterol synthesis, which is critical for maintaining cell membrane integrity. This compound exhibits activity against a range of fungal pathogens, making it suitable for applications in mycology research and exploring antifungal mechanisms. Its efficacy in treating fungal infections makes it a valuable reagent for studies focused on antifungal drug development and resistance mechanisms. -
CYP51 Inhibitor
CYP51-IN-30 is a potent inhibitor of CYP51, targeting sterol 14α-demethylase, an essential enzyme in sterol biosynthesis. This compound exhibits significant fungicidal activity, demonstrated by an EC50 value of 2.97 mg/L against Sclerotinia sclerotiorum. Its efficacy makes it a valuable tool for research in antifungal studies and applications in plant pathology. -
Antifungal Agent
Appenolide A is an antifungal furanone compound that derives from the coprophilous fungus Podospora appendiculata. It exhibits significant antifungal activity, making it a valuable tool for studying fungal biology and developing antifungal therapies. Its unique mechanism of action provides insights into fungal resistance and can aid in the discovery of new antifungal agents. -
Antifungal Agent
Rhizocticin A is an antifungal phosphono-oligopeptide that effectively targets fungi such as Ascodesmis, Plicaria, and Rhizoctonia. With a minimum inhibitory concentration (MIC) of 3.5 μg/mL, Rhizocticin A is capable of inhibiting fungal growth by producing the toxic metabolite L-2-Amino-5-phospho-3-cis-pentenoic acid (L-APPA), which disrupts vital cellular metabolism. This compound is valuable for research focused on fungal pathogenesis and the development of antifungal agents. -
Lead Compound
3-Amino-1,2,4-triazin-5(2H)-one is a lead compound targeting various biological pathways. This organic triazine derivative exhibits a wide array of biological activities, including antibacterial, antifungal, antiviral, and potential antitumor effects, which are influenced by its chemical structure and functional groups. It serves as a valuable reagent for research applications in pharmacology and medicinal chemistry, facilitating the discovery of new therapeutic agents. -
Fungicide
Iprovalicarb is a fungicide that functions by inhibiting fungal growth, targeting specific pathways involved in fungal cell metabolism. This compound is primarily utilized in research focused on fungal diseases, particularly within the winemaking industry. Its effectiveness against various fungal pathogens makes it a valuable tool for studying disease management strategies and developing protective measures in viticulture. -
Antifungal Agent
D13 is an acylhydrazone derivative that exhibits potent antifungal activity. It has demonstrated effectiveness against murine sporotrichosis, making it a valuable candidate for research in fungal infections. Its unique mechanism of action and efficacy profile support its potential applications in the study and treatment of antifungal resistance and related diseases. -
Anti-Fungal Agent
Haliangicin B is an anti-fungal agent primarily targeting filamentous fungi and demonstrating efficacy against oomycetes. This compound exhibits potent biological activity, making it useful for research applications focused on fungal pathogenesis and the development of antifungal therapies. Its selective action excludes antibacterial properties, positioning it specifically within the realm of mycology research. -
Antimicrobial Agent
Terrestribisamide, also known as (E)-N,N′-Diferuloylputrescine, serves as an antimicrobial agent derived from the dried fruits of Tribulus terrestris. This compound exhibits notable antibacterial, antifungal, antioxidant, and anticancer activities, making it a valuable tool for various biological research applications. Its diverse pharmacological properties contribute to its potential in studying microbial resistance and cancer therapies. -
Isomer of Pneumocandin B0
Pneumocandin C0 is an isomer of Pneumocandin B0 known for its antifungal properties. It exhibits significant activity against fungal infections, making it suitable for research in the development of antifungal agents. Derived from the fermentation of Glarea lozoyensis under conditions of high residual fructose concentration, Pneumocandin C0 serves as a valuable compound for studies focusing on fungal pathogenesis and treatment strategies. -
Fungal Inhibitor
BHBM is an aromatic acylhydrazone compound that acts as a potent antifungal agent targeting Cryptococcus neoformans. Its high bactericidal activity makes it a valuable tool for research applications focused on fungal infections and the development of new antifungal therapies. BHBM can be used to explore mechanisms of action and resistance in fungi, contributing to advancements in infectious disease research. -
Antifungal Agent
YZK-C22 is an antifungal agent characterized by its unique 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole framework. It exhibits broad-spectrum fungicidal activity, making it a promising candidate for developing effective antifungal treatments. This compound is suitable for research applications focused on fungal pathogen control and antifungal drug discovery. -
Anti-Fungal Agent
Neocopiamycin B is an antifungal agent derived from the strain Streptomyces hygroscopicus var. crystallogenes. It exhibits potent antifungal activity against various fungal pathogens, making it a valuable tool for studying fungal infections and developing new antifungal therapies. This compound is applicable in research focused on mycology and the exploration of novel antifungal mechanisms. -
Group II introns Inhibitor
Group II intron-IN-1 acts as an inhibitor of fungal Group II introns, demonstrating an IC50 of 3 μM. This compound is valuable for research focusing on fungal infections, particularly those caused by Candida species. Its ability to selectively target intronic processes makes it a significant tool for studying fungal biology and the mechanisms of infection. -
Anti-tubercular Agent
Giparmen is an anti-tubercular agent that demonstrates significant efficacy in targeting Mycobacterium tuberculosis. This compound shows promise for further research into fungal infections, specifically those caused by Candida species. Its unique mechanism and biological activity make it a valuable tool for investigators studying tuberculosis and fungal pathogenesis. -
Antifungal
Neocryptolepine-Cl is a selective inhibitor of Bcthi4, demonstrating potent antifungal activity against Botrytis cinerea, with an EC50 value of 0.56 μg/mL. This compound is useful for research applications targeting fungal pathogens, particularly in studies investigating antifungal mechanisms and resistance. Neocryptolepine-Cl may facilitate the development of new antifungal strategies and therapies. -
Phytoalexin
Moracin B is a phytoalexin targeting fungal pathogens. This compound exhibits significant antifungal activity and can be isolated from infected mulberry (Morus alba Linne) tissues, specifically the cortex and phloem, associated with Fusarium solani f. sp. mori. Moracin B serves as a valuable tool for investigating plant disease resistance mechanisms and demonstrates potential applications in the control of plant diseases caused by microbial infections. -
Antifungal Compound
Lanomycin is an antifungal compound that targets various fungal pathogens, including Candida species and dermatophytes. It exhibits potent antifungal activity, making it suitable for research applications focused on fungal infections and therapeutic development. Lanomycin's mechanism of action can help elucidate the biology of fungal resistance and guide the discovery of novel antifungal agents. -
Antifungal Agent
8-Acetylverrucarin L is a mycotoxin with potent antifungal properties. It demonstrates significant cytotoxicity against cancer cell lines HCT116 and A2780S, exhibiting an IC100 value of 9.77 ng/mL. In addition to its antitumor effects, 8-Acetylverrucarin L shows effective antifungal activity against Saccharomyces cerevisiae, Candida albicans, and Geotrichum candidum, making it a valuable reagent for research in both cancer biology and fungal infections. -
Anti-Fungal Agent
Phoslactomycin F is an anti-fungal agent that targets fungal organisms with high efficacy. It demonstrates weak activity against Gram-positive bacteria, highlighting its specific application in fungal research. This compound can be utilized in studies exploring fungal pathogenesis and the development of novel antifungal therapies. -
Anticancer And Antimicrobial Agent
α-Thujaplicin is a potent antimicrobial agent that exhibits anticancer activity by targeting Carboxypeptidase A, with an IC50 of 32.4 μM. This compound demonstrates significant antifungal activity against various plant-pathogenic fungi, with MICs ranging from 12.0 to 50.0 μg/mL. Additionally, α-Thujaplicin shows antibacterial properties against Legionella pneumophila and Enterococcus faecalis, with respective MICs of 12.5-50 μg/mL and 1.56 μg/mL. Moreover, it inhibits the germination of Echinochloa utilis seeds and has been associated with the suppression of lymphocytic leukemia and stomach cancer. -
Broad-spectrum antifungal Agent
Pramiconazole is a broad-spectrum antifungal agent that targets 14α-demethylase, disrupting ergosterol synthesis in fungal cell membranes. It exhibits oral bioactivity and is effective against a variety of fungal infections, including those affecting the skin, hair, nails, oral cavity, and genital mucosa. This compound is valuable in research focused on antifungal therapies and the mechanisms of antifungal resistance. -
Antifungal Agent
Antifungal Agent 150 is an antifungal compound primarily targeting ergosterol biosynthesis, effectively inhibiting key enzymes involved in this pathway. It demonstrates significant activity against phytopathogenic fungi, providing lesion suppression in planta. This agent is suitable for researching plant diseases caused by Rhizoctonia solani, including banded leaf and sheath blight in maize. -
Antifungal Metabolite
Dihydrocompactin is an antifungal metabolite that acts primarily as an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase). This compound, derived from Penicillium citrinum, exhibits significant antifungal activity and is valuable in studying fungal infections and metabolic pathways. Dihydrocompactin may be used in research focused on the development of antifungal agents and the elucidation of HMG-CoA reductase's role in cellular processes. -
Antifungal Agent
Anticapsin is a potent inhibitor of glucosamine-6-phosphate synthase, functioning primarily as an antifungal agent. It exhibits efficacy against various fungal pathogens by disrupting cell wall synthesis, leading to compromised integrity and cellular death. This compound is valuable in antifungal research applications, especially in studying mechanisms of resistance and evaluating new therapeutic strategies. -
Antifungal Agent
MFB-1041 is an orally active antifungal agent that targets fungal cell function. Though it has poor oral absorption, MFB-1041 is known to facilitate the binding of the drug to serum albumin, which may enhance its efficacy. This compound is utilized in research focused on antifungal mechanisms and therapeutic development. -
Antimicrobial Agent
Concanamycin F is a specific inhibitor of V-type ATPase, exhibiting a Ki value of 0.02 nM. This compound demonstrates a range of biological activities, including antifungal, antiviral, immunosuppressive, and cytotoxic effects. It serves as a valuable tool in biochemical research, enabling investigations into cellular processes and the study of ATPase function. -
Laccase Inhibitor
Laccase-IN-6 is a potent laccase inhibitor with an IC50 of 0.097 nM. This compound demonstrates a broad-spectrum anti-fungal activity, effectively disrupting normal fungal morphology. Laccase-IN-6 is suitable for research applications focused on fungal infections and the role of laccase in pathogenicity. -
Antifungal Agent
Dihydrobiochanin A is a flavonoid with demonstrated antifungal activity. Isolated from Swartzia polyphylla, it is primarily used in research to investigate its potential as a therapeutic agent against fungal infections. Its efficacy in combating various fungal strains makes it a valuable tool in the study of antifungal mechanisms and treatments. -
Antifungal Compound
SM-4470 is an orally active antifungal compound targeting a broad spectrum of fungal pathogens. It demonstrates significant inhibitory activity against yeast, Aspergillus species, and dermatophytes in vitro. This compound is suitable for research applications focused on antifungal mechanisms and the development of novel therapeutic strategies. -
Anti-Fungal Agent
Crotocin is an anti-fungal agent that primarily targets Cryptococcus neoformans, Candida albicans, and Trichophyton species. It exhibits significant biological activity against these fungi, making it valuable for research into antifungal therapies and mechanisms of action. Notably, its efficacy may be compromised in the presence of blood, indicating potential considerations for in vivo applications. -
Anti-Fungal Agent
Maniwamycin A is an anti-fungal agent that selectively inhibits fungal growth by interfering with cellular processes. This compound exhibits potent antifungal activity against a range of fungal strains, making it valuable for studying fungal biology and testing antifungal therapies. Its application in research provides insights into fungal resistance mechanisms and potential therapeutic strategies. -
Antifungal Agent
(E)-4-Methyl-5-styrylbenzene-1,3-diol is an antifungal agent that demonstrates significant activity against various fungal pathogens. This compound is notable for its potential applications in the development of antifungal therapies, with a natural source being Dracaena cochinchinensis (Lour.) S. C. Chen. Researchers may employ this reagent to explore mechanisms of antifungal action and to evaluate its efficacy in vitro and in vivo systems.
