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Tetrahydroechinocandin B

Catalog No.: A27099
Antifungal Agent
Tetrahydroechinocandin B is a potent antifungal agent that primarily inhibits 1,3-beta-D-glucan synthesis, exhibiting an IC50 value of 0.85 μg/mL. This mechanism of action disrupts fungal cell wall integrity, making it effective against various fungal pathogens. Tetrahydroechinocandin B is commonly utilized in research applications aimed at understanding antifungal mechanisms and developing therapeutic strategies against fungal infections.
Tetrahydroechinocandin B 54651-06-8 Antifungal Agent
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTetrahydroechinocandin B is a potent antifungal agent that primarily inhibits 1,3-beta-D-glucan synthesis, exhibiting an IC50 value of 0.85 μg/mL. This mechanism of action disrupts fungal cell wall integrity, making it effective against various fungal pathogens. Tetrahydroechinocandin B is commonly utilized in research applications aimed at understanding antifungal mechanisms and developing therapeutic strategies against fungal infections.
Product Information
Catalog NumA27099
FormulaC52H85N7O16
Molecular Weight1064.27
CAS Number54651-06-8
SMILESO=C(CCCCCCCCCCCCCCCCC)N[C@H](C(N[C@@]1([H])[C@H](O)C)=O)C[C@H]([C@H](NC([C@@]([C@H]2O)([H])N(C[C@@H]2C)C([C@](NC([C@](NC([C@@](C[C@H]3O)([H])N(C3)C1=O)=O)([H])[C@H](O)[C@H](C(C=C4)=CC=C4O)O)=O)([H])[C@H](O)C)=O)=O)O)O
SynonymsL-687901
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Microbiology > Antifection > Fungal