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7-O-Demethyl rapamycin

Catalog No.: A28279
Rapamycin Derivative
7-O-Demethyl rapamycin, a rapamycin derivative, primarily targets the mTOR pathway. This compound exhibits antifungal activity and demonstrates immunosuppressant properties, making it valuable in research related to immune response modulation. Additionally, 7-O-Demethyl rapamycin effectively inhibits tumor cell growth, contributing to studies on cancer biology and therapeutic strategies.
7-O-Demethyl rapamycin 151519-50-5 Rapamycin Derivative
Grouped product items
Size Price Stock Qty
2.5mg
$30.00
In stock
5mg
$60.00
In stock
10mg
$90.00
In stock
25mg
$150.00
In stock
50mg
$205.00
In stock
100mg
$275.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description7-O-Demethyl rapamycin, a rapamycin derivative, primarily targets the mTOR pathway. This compound exhibits antifungal activity and demonstrates immunosuppressant properties, making it valuable in research related to immune response modulation. Additionally, 7-O-Demethyl rapamycin effectively inhibits tumor cell growth, contributing to studies on cancer biology and therapeutic strategies.
Product Information
Catalog NumA28279
FormulaC50H77NO13
Molecular Weight900.15
CAS Number151519-50-5
SMILESO[C@]1(O[C@@](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C2=O)C)C)O)([H])CC[C@H]1C)C(C(N(CCCC3)[C@]3([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H]2OC)O)\C)C)=O)([H])[C@H](C)C[C@H](CC[C@H]4O)C[C@H]4OC)=O)=O)=O
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Microbiology > Antifection > Fungal