Mefentrifluconazole is a novel azole derivative that functions as a potent antifungal agent, targeting fungal CYP51 with a Kd of 0.5 nM. This compound exhibits broad-spectrum efficacy against various fungal pathogens while demonstrating significantly lower inhibitory activity on human aromatase, with an IC50 of 0.92 μM. It is suitable for research applications focusing on antifungal therapy and agrochemical development.
Mefentrifluconazole is a novel azole derivative that functions as a potent antifungal agent, targeting fungal CYP51 with a Kd of 0.5 nM. This compound exhibits broad-spectrum efficacy against various fungal pathogens while demonstrating significantly lower inhibitory activity on human aromatase, with an IC50 of 0.92 μM. It is suitable for research applications focusing on antifungal therapy and agrochemical development.
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