Catalog No.
Product Name
Application
Product Information
Citations
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Parasite Inhibitor
Phebestin is a compound that exhibits potent antimalarial activity by inhibiting the growth of Plasmodium spp. It demonstrates significant efficacy in both in vitro and in vivo studies. Additionally, Phebestin interacts with key enzymes associated with the Plasmodium life cycle, making it a valuable tool for research in parasitology and the development of novel antimalarial therapies. -
Parasite Inhibitor
M&B 5124 is a potent inhibitor targeting Schistosoma mansoni, a pathogenic trematode responsible for schistosomiasis. This compound demonstrates significant antiparasitic activity in murine models, making it a valuable tool for research into therapeutic strategies against schistosomiasis. Its efficacy positions it as a candidate for further studies aimed at understanding parasitic infections and developing new treatment options. -
Antileishmanial Agent
Antileishmanial agent-31 is a pyrazole derivative that targets Leishmania species. It exhibits significant anti-leishmanial activity, with an IC50 value of 35.53 μg/mL, indicating its potential effectiveness in combating leishmaniasis. This compound demonstrates high stability, making it suitable for research applications aimed at understanding and developing treatments for Leishmania infections. -
Parasite
Atropine Oxide is a derivative of Atropine that functions as a competitive antagonist at muscarinic acetylcholine receptors M1, M2, M3, M4, and M5. This compound exhibits significant biological activity in blocking parasympathetic neuro-transmission. It is primarily utilized in research applications focused on the treatment of specific nerve agent and pesticide poisonings. -
Parasite
Cardol triene is a phenolic compound that serves as a competitive and irreversible inhibitor of mushroom tyrosinase, with an IC50 of 22.5 μM. This compound exhibits significant schistosomicidal activity, demonstrating the ability to eliminate 25%, 75%, and 100% of Schistosoma mansoni worms within 24 hours at concentrations of 50, 100, and 200 μM, respectively. Additionally, Cardol triene is utilized as a precursor in the synthesis of bis-benzoxazines, making it a valuable reagent for research in parasitology and synthetic chemistry. -
Parasite Inhibitor
Melarsonyl dipotassium is a potent anthelmintic agent that targets various parasitic organisms. By interfering with metabolic processes in parasites, it exhibits significant inhibitory activity, making it valuable for research in parasitology and drug development. This compound is particularly relevant in studying the mechanisms of anthelmintic resistance and developing novel therapeutic strategies against parasitic infections. -
Parasite Inhibitor
trans-Cinnamic anhydride is a parasite inhibitor with a primary target of Plasmodium falciparum. This compound, isolated from Cinnamomum zeylanicum, demonstrates moderate antimalarial activity. It is utilized in pharmacological studies aimed at developing therapeutic agents against parasitic infections. -
Parasite
Pyriftalid is a novel insecticide that exhibits potent inhibitory activity against a range of pests. Its primary application in agriculture focuses on effectively managing pest populations in crops, which in turn enhances crop yield and quality. Additionally, Pyriftalid is being investigated for its potential to bolster plant resistance against both pests and diseases, making it an important tool in sustainable agricultural practices. -
Parasite Inhibitor
Epsiprantel is a potent anti-Echinococcus compound that functions as a parasite inhibitor, effectively inducing the death of protoscolex, larvae, and adult stages of the parasite in vitro. In vivo studies demonstrate its higher efficacy against mature worms compared to larvae, making it a valuable tool for research into Echinococcus infections and potential therapeutic strategies. Epsiprantel is characterized by its safety profile, showing no adverse side effects in tested models. -
Parasite Inhibitor
6-O-Methacrylate is a trilobolide derivative derived from the leaves of Wedelia trilobata, functioning primarily as a parasite inhibitor. It exhibits significant antimalarial activity with an IC50 of 8.9 μg/mL against the Plasmodium falciparum parasite. Additionally, 6-O-Methacrylate demonstrates antiviral properties by inhibiting the tobacco mosaic virus (TMV). This compound is valuable for research in parasitology and virology. -
Antileishmanial Agent
Eugenitin is a polyketide compound derived from the fungus Mycoleptodiscus indicus, serving as an antileishmanial agent. It demonstrates significant inhibitory activity against Leishmania major, with an LD50 of 39.9 μM, while exhibiting low cytotoxicity against various human cancer cell lines (IC50 > 131 μM). This profile makes Eugenitin a valuable compound for research focused on leishmaniasis and cancer biology. -
Parasite Inhibitor
Cyclobendazole is a benzimidazole derivative targeting protozoan parasites. It demonstrates potent in vitro activity against Trichomonas vaginalis and Giardia lamblia, with IC50 values of 1.1 μg/mL and 0.047 μg/mL, respectively. This compound is useful in research applications focused on combating protozoal infections and studying their biological pathways. -
Antileishmanial Agent
Antileishmanial agent-7 is an effective antileishmanial compound targeting Leishmania donovani. It demonstrates potent biological activity, with IC50 values of 6.89 μM against L. donovani and 259 μM against L-6. This agent can be utilized in research focused on leishmaniasis treatment and drug development. -
Parasite Inhibitor
Fenbendazole sulfone is a benzimidazole anthelmintic agent that acts as a parasite inhibitor. It is a minor metabolite of fenbendazole, demonstrating significant activity against various helminths. This compound is primarily utilized in research focused on parasitic infections and anthelmintic drug development. -
Parasite Inhibitor
Anti-infective agent 9 is an inhibitor of Plasmodium falciparum, exhibiting an IC50 of 600 nM, which targets metabolic pathways by downregulating pyruvate levels and interfering with the TCA cycle. This compound demonstrates favorable metabolic stability and low toxicity in human liver cells, making it a viable candidate for further research into antimalarial therapies. Additionally, studies suggest that its mechanism of action may involve pathways beyond 1-deoxy-D-xylulose-5-phosphate synthase (DXPS), highlighting its potential as a multifaceted therapeutic agent in combating malaria. -
Parasite Inhibitor
Lettowienolide is a geranylbenzoquinonoid that targets the Plasmodium falciparum malaria parasite. It demonstrates mild in vitro inhibitory activity, with an IC50 of approximately 20 μg/mL. This compound is relevant for research applications focusing on malaria treatment and the exploration of new therapeutic agents against parasitic infections. -
Antileishmanial Agent
Antileishmanial agent-24 (compound 33) is a potent antileishmanial agent, demonstrating an IC50 value of 5.39 μM against Leishmania amastigotes. This compound inhibits the viability of the pathogen, making it a valuable tool for research in treating leishmaniasis. Its efficacy supports further exploration in drug development and therapeutic applications against this infectious disease. -
Parasite Inhibitor
Amabiline is a natural compound derived from specific plant sources, exhibiting potent activity as a parasite inhibitor. It demonstrates notable biological effects that make it valuable for research involving parasitic infections. Amabiline’s unique pharmacological properties may also provide insights into potential therapeutic applications, while its safety profile warrants consideration in various experimental contexts. -
Parasite Inhibitor
Antimalarial Agent 3 is a potent parasite inhibitor that exhibits nanomolar antiplasmodial activity, with an IC50 value of 0.035 μM. This compound demonstrates a high selectivity index, indicating minimal toxicity to mammalian cells. Its effectiveness makes it a valuable tool for research focused on developing antimalarial therapies and understanding parasite biology. -
Antileishmanial Agent
Piperolactam A is a natural compound derived from the root of Piper betle, functioning as an effective antileishmanial agent. It demonstrates significant leishmanicidal activity against both wild type and drug-resistant strains of Leishmania donovani. This compound is valuable for research applications focused on developing treatments for leishmaniasis and examining mechanisms of drug resistance in parasitic infections. -
Parasite Modulator
TCMDC-125431 is a novel modulator of parasite calcium dynamics, primarily targeting the malaria parasite. It effectively disrupts the regulatory mechanisms of calcium signaling while showing minimal inhibition of heme crystallization. This compound holds potential for research applications in understanding malaria pathophysiology and identifying new therapeutic strategies against malaria. -
Parasite Inhibitor
LAPTc-IN-1 is a competitive inhibitor of acidic M17 leucinopeptidase (LAPTc), exhibiting a Ki value of 0.27 μM. This compound demonstrates potent antagonistic activity against the parasite Trypanosoma cruzi, making it a valuable tool for research into parasitic infections. Its specificity towards LAPTc positions it as a potential candidate for the development of therapeutic strategies targeting Chagas disease and other related conditions. -
Parasite Inhibitor
Linearolactone is a compound that exhibits potent anti-Giardia activity, primarily targeting Giardia trophozoites. It induces necrotic cell death in these parasites, which can be attributed to its interaction with a predicted target protein. This compound is valuable for research applications focused on parasitic infections and the development of new therapeutic strategies against Giardia. -
Parasite Inhibitor
Anti-parasitic agent 3 is a potent inhibitor targeting resistant parasites, exhibiting significant anti-parasitic activity. This compound is essential for research applications focused on parasitic infections and the development of effective treatments. Its mechanism of action provides valuable insights into overcoming resistance in various parasitic species. -
Parasite Inhibitor
SSJ-183 is a parasite inhibitor with notable antimalarial activity. It functions by modulating both the efficacy and pharmacokinetic properties relevant to antimalarial treatment. Studies have demonstrated its potential in antimalarial research, positioning SSJ-183 as a significant candidate for the development of new combination therapies targeting malaria. -
Parasite Inhibitor
GSK932121 is a selective antimalarial agent that targets the electron transport chain of Plasmodium falciparum by inhibiting cytochrome bc1 (complex III). This compound disrupts the parasite's metabolic processes, demonstrating significant activity against malaria. Due to its efficient five-step synthesis process, GSK932121 can be produced at kilogram scale, making it suitable for extensive clinical research applications. -
Parasite Inhibitor
MMV674850 is a potent inhibitor targeting asexual stage parasites, exhibiting IC50 values of 2.7 and 4.5 nM. This compound preferentially affects early-stage gametocytes, with an IC50 of 4.5 ± 3.6 nM, while late-stage gametocytes display an IC50 of 28.7 ± 0.2 nM. MMV674850 serves as a valuable tool for research focused on malaria and parasite biology, particularly in investigating gametocyte development and inhibition strategies. -
Antileishmanial Agent
Antileishmanial agent-3 is a potent inhibitor targeting Leishmania major, demonstrating significant growth-inhibitory activity. This compound is valuable for investigating leishmaniasis and exploring potential therapeutic strategies against this parasitic infection. Its mechanism of action makes it a useful tool in antileishmanial research applications. -
Parasite Inhibitor
PfPKG-IN-1 is an imidazole-based inhibitor targeting Plasmodium falciparum cGMP-dependent protein kinase (PfPKG). This compound exhibits significant biological activity by interfering with the function of PfPKG, an essential enzyme in the life cycle of the malaria parasite. PfPKG-IN-1 is utilized in research applications aimed at developing effective antimalarial therapies and understanding the molecular mechanisms of parasite survival and replication. -
Parasite Inhibitor
6-Benzylthioinosine acts as a potent inhibitor of parasite growth, demonstrating significant antileukemic activity by enhancing cytotoxic effects against acute myeloid leukemia cells. It operates by modulating cellular metabolism and influencing signaling pathways, particularly when used in combination with metformin. This compound is valuable for research applications focused on leukemia treatment and understanding metabolic regulation in cancer. -
Parasite Inhibitor
Antileishmanial agent-2 is a potent inhibitor targeting Leishmania parasites, demonstrating submicromolar antileishmanial activity with an IC50 value of 0.29 μM. This compound exhibits a high selectivity index, indicating minimal toxicity to mammalian cells. It is suitable for research applications focused on the development of therapies for leishmaniasis and related parasitic infections. -
Parasite Inhibitor
(+)-Isopulegol functions primarily as a parasite inhibitor, derived from the terpenoid constituents of Mentha canadensis L. It exhibits phagostimulatory effects on adult pests, particularly S. granarius and T. confusum, acting as a feeding attractant for adult T. confusum and larvae of T. granarium. This compound is valuable for research applications in pest control and management strategies targeting stored product insects. -
Antileishmanial Agent
LC-61 is a potent antileishmanial agent that exhibits significant efficacy with an IC50 value of 0.076 µM against intracellular Leishmania infantum. This compound is crucial for research in parasitology and can be utilized in studies focusing on leishmaniasis treatment and drug development. Its high potency makes it a valuable tool for investigating the mechanisms of action and therapeutic strategies against leishmanial infections. -
Anti-parasite Agent
ELQ-316 is an endochinlike quinolone compound that serves as an anti-parasitic agent. It exhibits significant efficacy against both acute and chronic experimental toxoplasmosis, making it a valuable tool in parasitology research. This compound's mechanism of action targets essential pathways in the parasite, providing insights into potential therapeutic strategies for Toxoplasma infections. -
Parasite
Doramectin monosaccharide, an acid degradation product of Doramectin, targets glutamate- and GABA-gated chloride channels in nematodes, enhancing their opening and resulting in effective anthelminthic activity. This compound is useful for studying the pharmacodynamics of anthelmintics and exploring mechanisms of resistance in parasitic infection research. Its significance lies in its role in understanding the biochemical pathways involved in nematode neuromuscular function and development. -
Parasite
Trimethacarb is a carbamate insecticide that primarily targets the nervous system of parasites. It inhibits key cholinesterase enzymes, leading to accumulation of acetylcholine and subsequent paralysis of target organisms. This compound is commonly utilized in research settings to study pest control methods and the biochemical mechanisms underlying insecticide action against various parasites. -
Parasite Inhibitor
SLU-10906 is a potent inhibitor targeting the protozoan parasite Cryptosporidium. Demonstrating significant efficacy in a cell-based infection model with an EC50 of 0.19 μM, SLU-10906 is non-cytotoxic, making it a valuable tool for investigating cryptosporidiosis. Its oral bioavailability further enhances its potential for preclinical studies and therapeutic exploration. -
Anti-parasite Agent
MED6-189 is an anti-parasitic agent that disrupts apicoplast function and vesicular trafficking in Plasmodium falciparum, with an inhibitory concentration (IC50) of less than 50 nM. This kalihinol analog specifically targets the apicoplast, a vital non-photosynthetic plastid in Apicomplexa parasites essential for isoprenoid synthesis. Its primary biological activity makes it an important tool for research in malaria treatment and the development of anti-parasitic strategies. -
Anti-Parasite Agent
NEU617 is an anti-parasite agent that targets the proliferation of human African trypanosomiasis (HAT) pathogens. It effectively inhibits Trypanosoma brucei with an EC50 of 42 nM and shows activity against T. cruzi with an EC50 of 1.8 μM. This compound is a derivative of Lapatinib, providing a novel approach for research applications focused on parasitic infections and potential treatment strategies. -
Parasite
Vinclozolin M2 is an active metabolite of vinclozolin, primarily functioning as an antagonist of the mineralocorticoid receptor (IC50 = 1,400 nM) and the androgen receptor (IC50 = 0.17 nM). This compound is obtained through esterase activity and decarboxylation processes in C. elegans and human liver microsomes. Vinclozolin M2 exhibits significant biological activity, making it useful for investigating receptor-mediated signaling pathways and studying endocrine disruption in parasitic and mammalian systems. -
Parasite Inhibitor
Carbonic anhydrase inhibitor 27 is a targeted antitrypanosomal agent that inhibits carbonic anhydrase activity, impacting parasite viability. This compound effectively reduces parasitic load in the bloodstream and enhances the survival rate of infected murine models. It is valuable for research applications focused on the treatment of parasitic infections such as Trypanosomiasis. -
Anti-Parasite Agent
Hynapene B is an effective anti-parasitic agent that targets Eimeria tenella. With a minimum inhibitory concentration (MIC) of 34.7 μM, it demonstrates significant biological activity in inhibiting the growth and development of this protozoan parasite. This compound is suitable for research applications focusing on the control of coccidiosis and other parasitic infections. -
Parasite
Japonilure is a synthetic chemical compound known for its role as a pheromone that attracts specific parasitic insects. It exhibits key biological activity in pest management by disrupting the life cycle of targeted insect populations. Research applications include exploring its potential as a biocontrol agent in agriculture and studying its behavioral effects on insect hosts. -
Parasite
Eprinomectin B1b is a member of the avermectin family, primarily targeting parasites. It exhibits potent anthelmintic and insecticidal properties, making it a valuable reagent in research applications focused on parasite control and management. Eprinomectin B1b is utilized in studies investigating its effects on helminths and arthropod pests, contributing to the development of effective treatment strategies in agricultural and veterinary settings. -
Antileishmanial Agent
Antileishmanial agent-34 is an aurone that exhibits potent antileishmanial activity, specifically targeting Leishmania species. This compound demonstrates efficacy against both extracellular forms of Leishmania major, Leishmania donovani, Leishmania infantum, and Leishmania enriettii, as well as intracellular forms of Leishmania donovani, with an IC50 value of less than 2 µg/mL. Antileishmanial agent-34 is a valuable tool for research focused on leishmaniasis and the development of new therapeutic strategies against this infectious disease. -
Parasite
Isonicotinaldehyde 2-pyridin is an antileishmanial compound targeting Leishmania species, particularly effective against the promastigotes of L. amazonensis and L. braziliensis. Its primary mechanism involves the enhancement of reactive oxygen species (ROS) production, leading to disruption of mitochondrial function in parasites. Notably, Isonicotinaldehyde 2-pyridin exhibits low toxicity to mouse macrophages, making it a promising candidate for further pharmacological studies in the treatment of leishmaniasis. -
Parasite Inhibitor
MMV665852 is an antischistosomal agent that targets Schistosoma mansoni, inhibiting worm viability in vitro. This compound has demonstrated efficacy in reducing worm burden in murine models of schistosomiasis, making it a valuable tool for research in parasitic disease treatment and prevention. -
Anti-Parasite Agent
Hynapene A is an anti-parasitic agent that targets Eimeria tenella, a coccidian parasite responsible for avian coccidiosis. This compound has a minimum inhibitory concentration (MIC) of 123 μM, demonstrating significant efficacy against the parasite. Hynapene A is useful in research applications aimed at understanding coccidiosis and developing effective treatments for parasitic infections in poultry. -
Anti-parasite Agent
Norselic acid B is a natural compound known for its anti-parasitic properties, primarily targeting the Leishmania parasite. Isolated from the Antarctic sponge Crella sp., norselic acid B exhibits significant biological activity against these pathogens, making it a valuable reagent for research applications focusing on Leishmaniasis and related parasitic diseases. Its unique origin and efficacy position it as a promising candidate for further investigation in the field of parasitology. -
Parasite
Z3-Dodecenyl E2-butenoate is a female sex pheromone synthesized by the sweet potato weevil, Cylas formicarius. This compound is utilized in baiting and trapping male weevils, facilitating effective population management in agricultural settings while minimizing reliance on chemical insecticides. Its application contributes to sustainable pest control strategies.
