Antileishmanial agent-34

Catalog No.: A52978
Antileishmanial Agent
Antileishmanial agent-34 is an aurone that exhibits potent antileishmanial activity, specifically targeting Leishmania species. This compound demonstrates efficacy against both extracellular forms of Leishmania major, Leishmania donovani, Leishmania infantum, and Leishmania enriettii, as well as intracellular forms of Leishmania donovani, with an IC50 value of less than 2 µg/mL. Antileishmanial agent-34 is a valuable tool for research focused on leishmaniasis and the development of new therapeutic strategies against this infectious disease.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAntileishmanial agent-34 is an aurone that exhibits potent antileishmanial activity, specifically targeting Leishmania species. This compound demonstrates efficacy against both extracellular forms of Leishmania major, Leishmania donovani, Leishmania infantum, and Leishmania enriettii, as well as intracellular forms of Leishmania donovani, with an IC50 value of less than 2 µg/mL. Antileishmanial agent-34 is a valuable tool for research focused on leishmaniasis and the development of new therapeutic strategies against this infectious disease.
Product Information
Catalog NumA52978
FormulaC15H10O3
Molecular Weight238.24
CAS Number139276-16-7
SMILESOC1=CC=C2C(/C(OC2=C1)=C/C3=CC=CC=C3)=O
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