Catalog No.
Product Name
Application
Product Information
Citations
-
Anthraquinone-type Natural Product
Chrysophanol dimethyl ether is an anthraquinone-type natural product that enhances the bioavailability of antibacterial and antifungal antibiotics. This compound serves as a chemical marker for distinguishing between raw and processed samples of Rheum palmatum, showing lower signal intensity in raw materials and higher intensity in processed forms. Chrysophanol dimethyl ether is valuable for research focusing on bacterial and fungal infections, facilitating the study of therapeutic efficacy and natural product chemistry. -
Antifungal/Antibacterial Benzoquinone
Anserinone B is a benzoquinone recognized for its antifungal and antibacterial properties. It effectively inhibits the radial growth of S. fimicola and A. furfuraceus by 50% and 37%, respectively. Additionally, Anserinone B exhibits moderate cytotoxicity against a broad range of human tumor cell lines, as demonstrated by a GI50 value of 4.4 µg/mL in the NCI’s 60 cancer cell line panel. This compound is relevant for research in antimicrobial therapies and cancer treatment. -
Natural Product
Cuspidiol is a natural product derived from the CH2Cl2 extract of Fagara zanthoxyloides Lam. It exhibits significant antifungal and antioxidant activities, making it a valuable reagent for studies in microbiology and oxidative stress research. Cuspidiol's diverse biological properties may offer insights into potential therapeutic applications and the mechanisms of action involved in fungal resistance and oxidative damage. -
Natural Products
Dehydro-α-lapachone is a natural product isolated from the methanol extract of Catalpa ovata G Don. It demonstrates significant antifungal activity, inhibiting the mycelial growth of Botrytis cinerea with an IC50 value of 0.41 mg/L. This compound is useful for research applications focused on natural antifungal agents and the study of fungal plant pathogenesis. -
Alkaloids
(-)-Antofine is a levorotatory alkaloid that exhibits significant antifungal activity. It serves as a valuable tool in biological research, particularly in studies focused on the mechanisms of fungal inhibition and the development of antifungal agents. This compound can aid in elucidating the interactions between alkaloids and fungal targets, contributing to the understanding of antifungal resistance and efficacy. -
Natural Products, ROS, Apoptosis
Macrocarpal C is a naturally occurring compound derived from the 95% ethanol extract of Eucalyptus globulus leaves, primarily targeting reactive oxygen species (ROS). It demonstrates significant antifungal activity by inhibiting the growth of Trichophyton mentagrophytes through increased permeability of the fungal membrane. Additionally, Macrocarpal C enhances the production of intracellular ROS, leading to apoptosis characterized by DNA fragmentation. This compound is valuable in research focusing on natural product pharmacology, fungal infections, and mechanisms of apoptosis. -
Natural Product
α-Guaiene is a sesquiterpene primarily derived from Pogostemon cablin, known as the main constituent of patchouli essential oil. It demonstrates notable antifungal activity against various Aspergillus species, making it a valuable compound for research in mycology and natural product pharmacology. α-Guaiene may be used in studies investigating the mechanisms of action of antifungal agents and the development of new therapeutic strategies. -
Natural Isoflavone
Luteone is a natural isoflavone known for its antioxidant, antibacterial, and antifungal properties. This compound plays a significant role in various biological processes and is utilized in research applications focusing on oxidative stress, microbial resistance, and pharmacological studies on plant-derived compounds. Luteone's diverse activities make it a valuable tool for understanding the therapeutic potential of isoflavones in health and disease. -
Quinolizidine Alkaloid
Tetrahydrorhombifoline is a quinolizidine alkaloid derived from the aerial parts of Genista vuralii A. Duran & H. Dural (Fabaceae). This compound exhibits significant antibacterial and antifungal activities, making it a valuable reagent for research in microbiology and pharmacology. Its potential applications extend to exploring natural product drug development and studying the mechanisms of antimicrobial action. -
Natural Compound
Valtrate hydrine B4 is a natural compound known for its antifungal properties. It exhibits biological activity by inhibiting the growth of various fungal strains, making it a valuable reagent for research in mycology and the development of antifungal therapeutics. This compound is useful for studies aimed at understanding fungal pathogenesis and screening potential antifungal agents. -
Natural Product
(-)-Dicentrine is an aporphine alkaloid derived from the stem bark of Talauma arcabucoana. This compound exhibits moderate antimicrobial activity, demonstrating growth inhibition against Staphylococcus aureus and Candida albicans. It serves as a valuable tool for studies exploring the therapeutic potential of natural products in combating bacterial and fungal infections. -
Natural Product
Ergosterol acetate is a natural product derived from fungi that serves as a potent precursor in the biosynthesis of various steroids. This compound exhibits significant biological activity, including modulating membrane permeability and serving as a valuable tool in studies of fungal metabolism and drug development. Ergosterol acetate is widely utilized in research applications focused on antifungal therapies and understanding lipid metabolism in eukaryotic cells. -
Cinnamaldehyde
3-Hydroxy-4-methoxycinnamaldehyde, a derivative of cinnamaldehyde, displays significant antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal properties with a minimum inhibitory concentration (MIC) ranging from 12.5 to 50 μg/mL. Isolated from the stem bark of Flemingia paniculata, this compound is suitable for research focused on microbial infections and the development of new antimicrobial agents. -
Antifungal Alkaloid
Norsanguinarine is an antifungal alkaloid that demonstrates potent activity against fungal pathogens, including Alternaria brassicicola and Curvularia maculans, at concentrations of 1000 ppm. This compound is of interest for research applications focused on the development of natural antifungal agents and the study of plant-microbe interactions. Its mechanism of action may provide insights into novel strategies for controlling fungal diseases in agricultural settings. -
Natural Product
Alloocimene is a diterpenoid that activates defense genes and enhances resistance to Botrytis cinerea in Arabidopsis thaliana. This compound serves as a valuable tool in plant research, particularly in studies examining plant-pathogen interactions and the regulation of defense mechanisms. Alloocimene can provide insights into the biochemical pathways involved in plant immunity and potential applications in agricultural biotechnology. -
Disaccharide
Nigerose is a disaccharide composed of glucose and fructose units. It exhibits potential biological activity in various metabolic pathways and is utilized in biochemical research to study carbohydrate interactions and enzymatic processes. Nigerose serves as an important tool in the exploration of glycoprotein dynamics and carbohydrate-based signaling in cellular systems. -
olysaccharide Copolymer
L-Triguluronic acid is a linear polysaccharide copolymer consisting of three L-guluronic acid units. It serves as a precursor to alginate, a class of unbranched polyanionic polysaccharides that exhibits significant biological activities. This compound is particularly useful in research focused on the development of delivery systems for anti-fungal agents, aiding in the exploration of innovative therapeutic strategies. -
Natural Product
Polypodine B is a natural ecdysone ester derived from the bark of Dacrydium intermedium. This compound exhibits significant inhibitory activity against Acanthamoeba castellani and demonstrates moderate antifungal properties. Polypodine B is valuable for research focused on parasitic diseases and fungal infections, providing insights into their mechanisms and potential therapeutic targets. -
Aromatic Aldehyde
Octanal is an aromatic aldehyde known for its antioxidant and antibacterial properties. It exhibits antifungal activity against G. citri-aurantii, potentially through the disruption of cell membrane integrity, leading to cellular component leakage. Furthermore, Octanal demonstrates cytotoxic effects on HeLa cells, with an IC50 value of 3.5 μg/mL, making it a valuable compound for research in cell biology and pharmacology. -
Antioxidant Agent
Clitorin is a flavonoid compound with potent antioxidant properties, primarily extracted from Carica papaya. Acting as an inhibitor of epidermal growth factor receptor (EGFR) and aromatase, Clitorin demonstrates significant anti-tumor activity. It exhibits IC50 values of 89.58 nM and 77.41 nM for EGFR and aromatase inhibition, respectively. Additionally, Clitorin influences lipogenesis and fatty acid oxidation, making it relevant for research related to non-alcoholic fatty liver disease. -
Natural Mineral
Talc is a naturally occurring mineral composed primarily of magnesium, silicon, and oxygen. Due to its unique properties, it serves as an effective excipient and absorbent in various cosmetic formulations, including powders and foundations. Talc’s primary role is to enhance texture, reduce friction, and absorb moisture, making it valuable in both research and application settings in the cosmetic and personal care industries. -
Phenol
Mequinol (4-Methoxyphenol) primarily targets phenolic compounds and serves as an important bioactive agent in dermatological research. It exhibits antioxidant properties and demonstrates additive or synergistic effects on carcinogenesis when used in combination with other phenolic antioxidants. Additionally, Mequinol promotes the production of chaperones dependent on the estrogen receptor alpha, indicating potential estrogenic activity for various applications in cancer and skin health research. -
Anthraquinone Glycoside
Sennoside is an anthraquinone glycoside that functions as a stimulant laxative. It promotes gastrointestinal motility and secretory actions by activating 5-HT4 receptors in the myenteric plexus and inhibiting Na+/K+-ATPase activity. This compound shows potential for research applications in chronic constipation and may facilitate investigations into gastrointestinal disorders. -
Natural Product
Tetracosane (ALKANE C24) is a natural product derived from Acrostichum aureum. It has demonstrated cytotoxic activity and the ability to induce apoptosis in various cell types. Tetracosane is of interest in research related to peptic ulcers, contributing to the understanding of its therapeutic potential in gastrointestinal health. -
Bioactive Natural Chalcone
Millepachine is a bioactive natural chalcone derived from Millettia pachycarpa Benth, demonstrating significant antitumor activity against various human cancer cell lines in both in vitro and in vivo studies. This compound serves as a valuable tool in cancer research, offering insights into potential therapeutic strategies targeting tumor growth and proliferation. Its natural origin and potent biological effects make Millepachine a promising candidate for further investigation in cancer pharmacology. -
Phenolic Compound
Hydroxytyrosol acetate is a prodrug of Hydroxytyrosol, functioning primarily as a phenolic compound. Upon administration, it is converted into the active Hydroxytyrosol form, which has been shown to alleviate oxidative stress and enhance mitochondrial function, contributing to neuroprotective effects. This compound can induce apoptosis in cancer cells by increasing reactive oxygen species (ROS) production and exhibits both antibacterial and antiviral properties. Hydroxytyrosol acetate is relevant for research into various diseases, including cancer, infections, inflammatory conditions, metabolic disorders, and neurodegenerative diseases such as Alzheimer's Disease and atherosclerosis. -
Natural Compound
2-Hydroxy-3-methylanthraquinone selectively targets protein tyrosine kinases, specifically v-src and pp60src. This natural compound, derived from Hedyotis diffusa WILLD, demonstrates significant inhibitory activity, leading to growth arrest and apoptosis in HepG2 cancer cells. Its biological properties make it a valuable tool for cancer research and studies focused on kinase signaling pathways. -
Phenolic Compound
Cardanol monoene is a phenolic compound derived from cashew nut shell liquid, primarily targeting cellular mechanisms involved in cancer progression. It exhibits significant anti-cancer activities, including the inhibition of cell proliferation and migration, S phase arrest, and induction of apoptosis via reactive oxygen species (ROS) production and mitochondrial depolarization. Cardanol monoene modulates key signaling pathways by downregulating MMP-2 and MMP-9 expressions and regulating the expression of CDK2, p53, and Bax, among others. Additionally, it demonstrates weak DPPH radical scavenging and acetylcholinesterase inhibition activities, making it suitable for research in cancer, infection, and inflammation. -
2-Hydroxycinnamaldehyde
(E)-2-Hydroxycinnamaldehyde is an aldehyde primarily targeting the STAT3 signaling pathway. It exhibits significant biological activity by inhibiting cell proliferation and inducing apoptosis through the modulation of reactive oxygen species production. This compound is valuable in cancer research, demonstrating antitumor effects and potential therapeutic applications in oncological studies. -
Quaternary Isoquinoline Alkaloid
Columbamine is a quaternary isoquinoline alkaloid that acts primarily by inhibiting the cytochrome P450 isoform CYP3A4, with an IC50 of 30.6 µM. This compound demonstrates significant biological activities, including the induction of apoptosis in cancer cells, as well as antioxidant, anti-inflammatory, antitumor, antifungal, antiparasitic, hepatoprotective, neuroprotective, hypolipidemic, and hypoglycemic effects. It is suitable for various research applications exploring therapeutic interventions and mechanisms in cancer and metabolic diseases. -
Natural Product
Ginsenoside F4 (GF4) is a natural product derived from notoginseng and red ginseng, with a primary mechanism of inducing apoptosis in human lymphocytoma JK cells. GF4 demonstrates biological activity by inhibiting the expression of matrix metalloproteinase 13 (MMP-13) in interleukin-1β-treated chondrocytes. This compound shows promise in therapeutic applications aimed at preventing cartilage breakdown and preserving collagen matrix integrity in diseased tissues, particularly in cartilage research. -
Flavonoid
5,6,7,8,4'-Pentahydroxyflavone is a flavonoid with demonstrated antitumor activity. It exerts cytotoxic effects through the inhibition of cell proliferation and the induction of apoptosis. This compound is valuable for cancer research, facilitating studies on cellular mechanisms and potential therapeutic applications in oncology. -
Phenolic Compound
Hydroxytyrosol-d4 is a deuterium-labeled derivative of Hydroxytyrosol, a phenolic compound abundant in olive oil. This compound exhibits antioxidant properties, mitigating oxidative stress and enhancing mitochondrial function, which contributes to its neuroprotective effects. Hydroxytyrosol-d4 is involved in promoting apoptosis in cancer cells through the production of reactive oxygen species (ROS) and demonstrates antibacterial and antiviral activities. It serves as an important tool in research on cancer, infections, inflammation, immunology, metabolic conditions, neurology, and cardiovascular diseases, including colon cancer, diabetes, Alzheimer’s disease, and atherosclerosis. -
Active Alkaloid
Neoechinulin A is an isoprenyl indole alkaloid that primarily acts as an active scavenger. This compound demonstrates neurotrophic factor-like properties and exhibits anti-apoptotic effects. Research indicates that Neoechinulin A can enhance memory and produce antidepressant-like effects in murine models, making it a valuable tool for investigations in neurobiology and mental health studies. -
Natural Product
Pectic acid, a polygalacturonic acid, primarily targets cancer cells by inducing apoptosis and necrosis in pituitary tumor cells. Its key biological activity makes it a valuable reagent in cancer research and studies related to autoimmune diseases. Pectic acid's role in modulating cellular processes provides useful insights into therapeutic strategies for various malignancies and immune disorders. -
Anticancer Agent
Sotetsuflavone is a flavonoid extracted from Cycas revolute, primarily targeting cancer cell migration and invasion. It has been shown to reverse epithelial-mesenchymal transition (EMT), induce apoptosis, and activate autophagy in A549 lung cancer cells. Additionally, Sotetsuflavone downregulates key factors such as HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13, contributing to its anticancer properties. This compound is also investigated for its protective effects in models of Crohn's disease-like colitis, making it a valuable reagent for research in non-small cell lung cancer (NSCLC) and inflammatory bowel diseases. -
Natural Product
Vitexilactone is a diterpenoid derived from the leaves of Vitex negundo L. It exhibits antimicrobial properties against E. coli and has demonstrated the ability to induce apoptosis in cancer cells while inhibiting their cell cycle progression. This compound is particularly valuable for research in cancer biology and microbiology. -
Isoquinoline Alkaloid
Chelidonine hydrochloride is a potent isoquinoline alkaloid derived from Chelidonium majus L. This compound induces G2/M cell cycle arrest and triggers both caspase-dependent and caspase-independent apoptosis, effectively inhibiting stem cell proliferation in Dugesia japonica. Chelidonine hydrochloride demonstrates significant cytotoxic effects against melanoma cell lines, along with notable anticancer and antiviral properties. Its unique biological activities make it a valuable reagent for cancer research and antiviral studies. -
Natural Product
Dehydroeffusol is a phenanthrene derivative isolated from the medicinal herb Juncus effusus. This compound demonstrates potent inhibitory effects on gastric cancer cell proliferation and tumorigenicity by selectively triggering endoplasmic reticulum stress and modulating apoptotic pathways. Notably, Dehydroeffusol exhibits low toxicity, making it a promising candidate for further research in cancer treatment applications. -
Natural Products
Celosin K is a natural product isolated from the seeds of Semen Celosiae, known for its potent inhibitory effects on neuron injury induced by t-BHP. This compound demonstrates significant activity in mitigating oxidative stress and apoptosis, while promoting autophagy. Celosin K is valuable for research applications focused on neuroprotection, oxidative stress, and apoptosis mechanisms. -
Natural Compound
Pancratistatin is an isoquinoline alkaloid derived from the plant Hymenocallis littoralis. It is known to induce apoptosis in human melanoma cells, showcasing its potential as an anticancer agent. This compound is relevant for research applications in various cancer types, including neuroblastoma, leukemia, and breast cancer. -
Natural Products
Shizukaol D is a dimeric sesquiterpene derived from Chloranthus serratus that primarily targets the induction of apoptosis in cellular systems. This compound exhibits significant inhibitory effects on Wnt signaling pathways, making it a valuable tool for research in cancer biology and the study of cell signaling mechanisms. Its unique properties make Shizukaol D an important candidate for investigating therapeutic strategies against Wnt-related diseases. -
Aporphine Alkaloid
Xylopine is an aporphine alkaloid that targets cancer cells with potent cytotoxic activity. It induces oxidative stress, leading to G2/M cell cycle arrest and apoptosis in these cells. Xylopine is primarily utilized in cancer research to explore mechanisms of cell death and to evaluate potential therapeutic strategies. -
Triterpenoid Saponin
Pulchinenoside B is a triterpenoid saponin derived from Pulsatilla chinensis. This compound exhibits various biological activities, including anti-inflammatory and antioxidant effects, and has been studied for its potential therapeutic applications in cancer and cardiovascular diseases. Researchers may find Pulchinenoside B valuable in exploring its mechanistic roles in cellular processes and its potential as a lead compound in drug development. -
Anti-Cancer Agent
Glycoborinine is a natural carbazole alkaloid extracted from Glycosmis pentaphylla, primarily acting as an anti-cancer agent. It induces apoptosis in HepG2 cells through the mitochondrial pathway, showcasing significant potential for cancer research. Additionally, Glycoborinine demonstrates the ability to inhibit HIV replication in cultured cells, highlighting its versatility in various biological applications. -
Flavonoid Antioxidant
Quercetin hydrate is a natural flavonoid with potent antioxidant properties, primarily targeting SIRT1. It acts as a stimulant for recombinant SIRT1 and serves as an inhibitor of phosphoinositide 3-kinases (PI3K), exhibiting IC50 values of 2.4 μM, 3.0 μM, and 5.4 μM for PI3K γ, PI3K δ, and PI3K β, respectively. This compound is widely used in research applications focused on cellular signaling, oxidative stress, and metabolic diseases. -
Phenolic Compound
Hydroxytyrosol is a phenolic compound primarily derived from olive oil, recognized for its antioxidant properties. It mitigates oxidative stress and enhances mitochondrial function, which contributes to its neuroprotective effects. Additionally, Hydroxytyrosol induces apoptosis in cancer cells through the generation of reactive oxygen species (ROS) and exhibits antibacterial and antiviral activities. This compound is applicable in research related to cancer, infectious diseases, inflammation, immunology, and conditions such as diabetes, Alzheimer's disease, and atherosclerosis. -
Phospholipid
Cardiolipin (Heart, Bovine) sodium is a specific phospholipid found predominantly in mitochondria, extracted from bovine heart tissue. This compound plays a crucial role in maintaining mitochondrial function, regulating cellular metabolism and signaling processes, as well as inducing apoptosis and autophagy. Cardiolipin (Heart, Bovine) sodium is suitable for applications in inflammation, immunology, cardiovascular research, and studies of neurological diseases. Additionally, it can be coated onto microplate wells for use in ELISA assays. -
Natural Product
Daucosterol is a natural sterol compound with demonstrated anti-inflammatory, anticancer, and immunomodulatory properties. It exerts its effects by inducing autophagy through a reactive oxygen species (ROS)-dependent mechanism, inhibiting the proliferation of cancer cells. Additionally, Daucosterol impedes colon cancer growth by promoting apoptosis, suppressing cell migration and invasion, and engaging the caspase signaling pathway, making it a valuable tool for research in cancer biology and therapeutic development. -
Apoptosi Inducer
4-Vinylphenol (10% in Propylene Glycol) is a potent apoptosis inducer targeting cancer cell viability and angiogenesis. Extracted from the medicinal herb Hedyotis diffusa and produced by lactic acid bacteria during the metabolism of p-coumaric and ferulic acid, this compound demonstrates significant anti-cancer activity. It inhibits blood vessel formation and suppresses the growth of invasive breast tumors in vivo, making it a valuable tool for cancer research and therapeutic studies.
