Sotetsuflavone is a flavonoid extracted from Cycas revolute, primarily targeting cancer cell migration and invasion. It has been shown to reverse epithelial-mesenchymal transition (EMT), induce apoptosis, and activate autophagy in A549 lung cancer cells. Additionally, Sotetsuflavone downregulates key factors such as HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13, contributing to its anticancer properties. This compound is also investigated for its protective effects in models of Crohn's disease-like colitis, making it a valuable reagent for research in non-small cell lung cancer (NSCLC) and inflammatory bowel diseases.
Sotetsuflavone is a flavonoid extracted from Cycas revolute, primarily targeting cancer cell migration and invasion. It has been shown to reverse epithelial-mesenchymal transition (EMT), induce apoptosis, and activate autophagy in A549 lung cancer cells. Additionally, Sotetsuflavone downregulates key factors such as HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13, contributing to its anticancer properties. This compound is also investigated for its protective effects in models of Crohn's disease-like colitis, making it a valuable reagent for research in non-small cell lung cancer (NSCLC) and inflammatory bowel diseases.
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