Catalog No.
Product Name
Application
Product Information
Citations
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Multifunctional Natural Flavonoid Glycoside
Rutin trihydrate is a multifunctional natural flavonoid glycoside primarily known for its antioxidant and anti-inflammatory properties. This compound exhibits significant activity in countering diabetic complications and shows potential anti-carcinogenic effects. Research applications for rutin trihydrate include investigations into cardioprotection and neuroprotection, making it a valuable reagent for studies in various areas of health and disease. -
Human Milk Oligosaccharide
Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide known for its antiviral and antibacterial properties. It acts by reducing the capsid protein VP1, thereby blocking virus adsorption, and promotes the regulation of CDK2 and cyclin E to restore the S phase of the cell cycle. Additionally, LNFPI inhibits reactive oxygen species (ROS) production and apoptosis in virus-infected cells. Its ability to regulate intestinal microbiota also highlights its potential role in influencing immune system development. -
Flavonoid compound
Isoxanthohumol is a flavonoid compound known for its diverse biological activities, including anti-tumor, anti-inflammatory, antioxidant, antiviral, and antifungal properties. This compound has been shown to induce apoptosis, autophagy, and cell migration in tumor cells, making it a valuable tool for cancer research. Additionally, Isoxanthohumol exhibits efficacy against various viruses, including HSV, BVDV, CMV, and rhinovirus. It is applicable in studies related to tumors, metabolic disorders, and inflammatory diseases. -
Diterpenoid
Lasiokaurin is a diterpenoid compound that exhibits a range of biological activities. Isolated from Isodon lasiocarpus, it has been studied for its potential anti-inflammatory and anticancer properties. This compound serves as a valuable tool in chemical research focused on natural products and their therapeutic applications. -
Quaternary Isoquinoline Alkaloid
Columbamine chloride is a quaternary isoquinoline alkaloid known for its biological activity as a cytochrome P450 (CYP) isoform CYP3A4 inhibitor, with an IC50 of 30.6 µM. This compound induces apoptosis in cancer cells and exhibits a range of biological effects, including antioxidant, anti-inflammatory, antitumor, antifungal, antiparasitic, hepatoprotective, neuroprotective, hypolipidemic, and hypoglycemic properties. Columbamine chloride is suitable for various research applications focusing on cancer biology, metabolic disorders, and neuroprotection. -
Vnca Alkaloid
Vindoline, a vinca alkaloid, primarily targets tubulin by exhibiting a weak inhibitory effect on its self-assembly. Derived from the leaves of Catharanthus roseus, Vindoline demonstrates biological activity in modulating apoptosis and inhibiting key signaling pathways involving p-p65 and p-ERK. This compound has potential applications in research related to diabetes, bone loss, osteoarthritis, and kidney damage. -
Sesquiterpenoid
ar-Turmerone is a sesquiterpenoid derived from the herb Curcuma longa, known for its anti-tumorigenic and anti-inflammatory properties. It has been shown to induce apoptosis in U937 cells and positively modulate murine dendritic cells. Additionally, ar-Turmerone promotes neural stem cell proliferation in both in vitro and in vivo studies, making it useful for research on various neurological disorders. -
Triterpenoid
Gypenoside A is a triterpenoid compound derived from Gynostemma pentaphyllum, known for its anti-inflammatory and antioxidant properties. This compound exhibits protective effects on cardiomyocytes by inhibiting apoptosis, making it a valuable tool in studying cardiovascular diseases. Additionally, Gypenoside A is relevant for research into inflammation-related disorders, contributing to the understanding of various pathophysiological mechanisms. -
Methoxyflavonoid
Pachypodol is a methoxyflavonoid that primarily activates the ERK-dependent Nrf2 pathway while inhibiting apoptosis. This compound exhibits notable biological activities, including antioxidant, cytoprotective, and anti-inflammatory effects. Research applications include its potential to enhance cognitive function and provide protective effects against cardiac and liver damage. Additionally, Pachypodol demonstrates anticancer activity, particularly against colon cancer, making it a valuable reagent for various biomedical studies. -
Flavonoid
PERK/eIF2α activator 1 is a flavonoid that primarily activates the PERK-eIF2α-ATF4 signaling pathway, exerting significant anti-tumor activity. This compound effectively induces apoptosis in cancer cells and shows a notable inhibition of HepG2 cell proliferation, with an IC50 value of 23 μM. Its mechanism and biological effects make it a valuable tool for research in cancer biology and therapeutic development. -
Diterpenoid Compound
Ferruginol, a natural diterpenoid compound, primarily acts as an inhibitor of Epstein-Barr virus early antigen (EBV-EA) activation. This compound exhibits significant biological activity by inducing mitochondrial apoptosis, which contributes to its efficacy against thyroid cancer cells. Additionally, Ferruginol demonstrates antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective properties, making it a valuable reagent for cancer research and studies on cellular protection mechanisms. -
Triterpenoid Aglycone
Soyasapogenol A is a triterpenoid aglycone derived from soyasaponins. It exhibits notable anti-inflammatory, anti-cancer, and hepatoprotective properties, along with antiviral activity against HSV-1. This compound is valuable for research applications focusing on tumor biology and immune-inflammatory diseases. -
Alkaloid
(Z)-Indirubin is a bis-indole alkaloid that primarily targets multiple signaling pathways associated with cancer progression. This compound exhibits significant anticancer activity, particularly against chronic myelogenous leukemia (CML). Researchers can utilize (Z)-Indirubin for investigations into cancer biology and the development of novel therapeutic strategies targeting CML and other malignancies influenced by similar pathways. -
Cucurbitane-Type Triterpenoid
25-Deacetylcucurbitacin A is a Cucurbitane-Type triterpenoid that targets the JAK/STAT3 signaling pathway. It exhibits significant potential as an anti-cancer agent, demonstrating the ability to inhibit tumor growth and promote apoptosis in malignant cells. This compound can be utilized in research focused on cancer therapeutics and the modulation of tumor-related signaling pathways. -
Flavonoids
3',4'-Dihydroxyflavone is a flavonoid that exhibits notable antiallergic activity, with an IC50 value of 30 μM. This compound serves as a valuable tool for investigating type I allergies and their underlying mechanisms. Its biochemical properties make it suitable for research focused on inflammation and allergic responses. -
Tyrosinase Inhibitor
Kurarinol is a flavanone extracted from the root of Sophora flavescens that functions as a competitive inhibitor of tyrosinase, exhibiting an IC50 value of 0.1 μM against mushroom tyrosinase. This compound is primarily utilized in research focused on skin pigmentation and related disorders, making it valuable in the study of melanogenesis and potential therapeutic applications in hyperpigmentation. -
Phenolic Heterocyclic Compound
Antioxidant agent-21 is a phenolic heterocyclic compound that demonstrates potent antioxidant and anticancer properties. This compound exhibits significant cytotoxic effects against human gastric adenocarcinoma (AGS) and lung cancer (A549) cell lines, highlighting its potential in cancer research. Additionally, Antioxidant agent-21 induces caspase-dependent apoptosis in these cancer cells, making it a valuable tool for studies on cancer therapeutics and apoptosis mechanisms. -
Antitumor Alkaloid
Angustilongine M is a microtubule-targeting antitumor alkaloid that demonstrates significant cytotoxicity with an IC50 of 0.2 μM against HT-29 colorectal cancer cells. This compound induces G0/G1 cell cycle arrest and promotes mitochondrial apoptosis through enhanced tubulin polymerization. Angustilongine M is valuable for research applications related to colorectal cancer and other solid tumors. -
natural product
Diselaginellin B is a natural product derived from Selaginella pulvinata, known for its potent anti-proliferative effects. It induces apoptosis and demonstrates significant antimetastatic activity in human hepatocellular carcinoma cells. This compound is valuable for research applications focusing on cancer biology and therapeutic development. -
Alkaloid
Cinchonine hydrochloride is a natural alkaloid derived from Cinchona bark, primarily known for its antimalarial activity. This compound effectively activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells, making it a valuable tool in cancer research. Its unique mechanism and biological activity provide insights into therapeutic strategies targeting liver malignancies and highlight its potential in studying ER stress responses. -
Steroidal Alkaloid
Solasodine hydrochloride is a steroidal alkaloid derived from plants in the Solanaceae family. It exerts its biological activity by inducing apoptosis through the inhibition of the p53-MDM2 complex, as well as modulating the expression of p21Waf1/Cip1 and Bcl-2 proteins. This compound showcases a variety of therapeutic potentials, including neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic, and anti-inflammatory effects, making it suitable for diverse research applications in pharmacology and toxicology. -
Natural Sunscreen
Gadusol is a natural sunscreen synthesized by the mother during oogenesis, providing vital protection against UVB-induced DNA damage in early developmental stages of fish. By preventing cellular stress and apoptosis, Gadusol serves as a primary sunscreen mechanism stored in eggs. This compound does not exhibit antioxidant properties in zebrafish embryos, making it particularly relevant for studies in topical photoprotective cosmetics. Its unique protective qualities enhance research into natural photoprotection strategies. -
Alkaloid
Harmalol is a β-carbazine alkaloid that exhibits significant anticancer activity by targeting nucleic acids. It binds to both natural and synthetic DNA and RNA with varying motifs, facilitating its interactions. Harmalol also induces apoptosis in human hepatoma cells in vitro, making it a valuable reagent for cancer research and studies involving nucleic acid interactions. -
Natural Product
Barbigerone, a natural product derived from Amomum nilgiricum, is characterized by its unique chemical structure. This compound exhibits significant biological activity, serving as a valuable resource for research in various fields, including pharmacology and biochemistry. Its potential applications include the exploration of therapeutic properties and interactions within biological systems, making it an important tool for studying natural bioactive compounds. -
Alkaloid
Pipermethystine is an alkaloid isolated from the Kava plant, known to modulate cellular energy dynamics. It decreases ATP levels and mitochondrial membrane potential in HepG2 cells, ultimately leading to the induction of apoptosis. This compound is of interest for research focused on cancer biology and mitochondrial function. -
Flavonoids
3′-Hydroxyflavanone is a cyclized flavanone that primarily targets flavonoid pathways. It has been shown to induce apoptosis in HeLa cells and exhibits significant antitumor activity. This compound is valuable for research applications focused on cancer biology and the therapeutic potential of flavonoids in tumor suppression. -
Natural Product
Aloin (mixture of A&B) is an orally active anthraquinone derivative derived from Aloe vera, known for its extensive biological activities. It demonstrates neuroprotective, anti-inflammatory, antioxidant, antibacterial, antifungal, antiviral, and antitumor properties. Aloin inhibits key enzymes such as Clostridium histolyticum collagenase, granulocyte matrix metalloproteinases, and the human 20S proteasome, while modulating important pathways including Nrf2/HO-1 and TGF-β/Smad2/3. Its application extends to research involving chronic ulcers, burns, wounds, inflammatory and degenerative disorders, asthma, and neuroblastoma. -
Flavonoid Glycoside
Luteolin-7-rutinoside is a flavonoid glycoside known for its anti-arthritic and antifungal properties. This compound can be utilized in combination therapies targeting fungal arthritis, particularly in cases associated with Candida albicans infection. Its diverse biological activities make it a valuable tool for research in inflammatory diseases and mycological studies. -
Natural Alkaloid
Isoharringtonine is a natural alkaloid derived from Cephalotaxus koreana Nakai. This compound demonstrates significant inhibitory effects on cancer cell proliferation and migration, while also promoting apoptosis in cancer cells. Isoharringtonine is useful in cancer research, particularly in studies exploring therapeutic strategies and mechanisms of action against various malignancies. -
Alkaloid
Mycoleptodiscin A is a cytotoxic indole alkaloid derived from fungi, primarily known for its pro-apoptotic activity and ability to disrupt cell cycle progression. It is utilized in research to investigate mechanisms of apoptosis and assess potential therapeutic applications in cancer treatment. This compound serves as a valuable tool for studying the biological effects of alkaloids on cellular processes. -
Natural Compound
Uvaol diacetate is a triterpenoid derived from the leaves of Nerium oleander L. This compound exhibits protective effects against DNA damage and has been shown to induce apoptosis in cancer cells. Research applications include investigations into its potential as a therapeutic agent in cancer treatment and its protective roles in cellular biology. -
Active Natural Molecule
Viridiflorol is an active natural molecule recognized for its anti-cancer properties. It induces apoptosis in various cancer cell lines, demonstrating effective anti-neoplastic activity with IC50 values of 10 µM for breast (MCF-7), 30 µM for lung (A549), and 0.1 µM for brain (Daoy) cancer cells. This compound is valuable for research aimed at understanding and treating breast, lung, and brain cancers. -
Pentachlorophenol Metabolite
Tetrachlorohydroquinone (TCHQ) is a metabolite of pentachlorophenol known for its ability to induce reactive oxygen species (ROS) production. It has been shown to inhibit apoptosis and promote necrosis in primary mouse splenocytes. Additionally, TCHQ increases DNA lesions and induces oxidative stress in rodent models, making it a valuable tool for studying oxidative damage and cellular stress responses in toxicology and environmental research. -
Anti-pathoangiogenic Polysaccharide
CM101 is an anti-pathoangiogenic polysaccharide derived from group B streptococcus. It exhibits significant biological activity by inhibiting inflammatory angiogenesis and promoting wound healing in mouse models, while also minimizing scarring following spinal cord injury. Additionally, CM101 induces rapid tumor neovascularization and inflammatory cell infiltration, leading to inhibition of tumor growth and promotion of tumor apoptosis, making it valuable in cancer research and therapeutic studies. -
Natural Product
Embinin is a natural product derived from the petals of Iris germanica Linnaeus, known for its ability to enhance lumbar disc neovascularization. This compound induces apoptosis in nucleus pulposus cells, demonstrating potential applications in research related to lumbar disc herniation and associated therapeutic strategies. Its biological activity may offer insights into tissue regeneration and injury recovery processes. -
Glycoalkaloid
Tomatine hydrochloride is a glycoalkaloid derived from the tomato plant (Lycopersicon esculentum Mill.). It has been shown to induce neurotoxicity through mechanisms that are independent of RIP1 kinase and caspases, leading to the upregulation of nuclear apoptosis-inducing factor (AIF) in neuroblastoma cells. Additionally, tomatine hydrochloride inhibits 20S proteasome activity, making it a valuable reagent for research applications in cancer biology and neurodegeneration studies. -
Steroidal Alkaloid Glycoside
Esculeoside A is a spirosolane-type steroidal alkaloid glycoside that primarily targets NF-κB and Nrf2/Keap1 signaling pathways. This compound exhibits significant cardioprotective and hypoglycemic properties, regulating glucose metabolism and modulating lipid profiles. Research applications include the study of diabetic cardiomyopathy, type 2 diabetes, atopic dermatitis, tumors, and atherosclerotic diseases. Additionally, Esculeoside A inhibits dendritic cell maturation and T-cell proliferation, and exhibits anti-tumor activity against breast cancer and melanoma cells. -
Natural Product
Altechromone A is a natural product derived from Polygonum cuspidatum, exhibiting significant potential as a bioactive compound. It has demonstrated various biological activities, including antioxidant and anti-inflammatory effects. This compound is valuable for research applications focusing on natural product chemistry and the exploration of therapeutic agents targeting oxidative stress-related disorders. -
Natural Product
(-)-Sativan is a natural product classified as a flavonoid, primarily isolated from the leaves of birdsfoot trefoil. This compound exhibits various biological activities, including antioxidant properties, which may contribute to its potential applications in research focused on plant-based therapeutics and the study of phytochemicals. Its unique profile makes it valuable for investigations in biochemistry and pharmacology. -
Natural Product
Sesame Oil is a natural product derived from the seeds of Sesamum indicum L. It exhibits a variety of biological activities, including the ability to reduce NF-κB, aspartate aminotransferase, alanine aminotransferase, IL-1β, IL-4, and nitric oxide levels. Sesame Oil demonstrates antitumor activity against malignant melanoma and provides protective effects against liver damage induced by agents such as Cisplatin and Acetaminophen. Additionally, it possesses notable antinociceptive and anti-inflammatory properties, making it a valuable reagent for various research applications. -
Monosaccharide
Rhamnose (L-Rhamnose) is a naturally occurring deoxysugar that primarily targets inflammatory pathways. It has been shown to inhibit pro-inflammatory interleukins and matrix metalloproteinases (MMPs) in models of skin aging, highlighting its potential in anti-aging research. Additionally, Rhamnose enhances the phosphorylation of protein kinase A (PKA) substrates and hormone-sensitive lipase (HSL) in adipocytes, promoting PKA signaling and fat metabolism. Its ability to stimulate dopamine receptors and induce thermogenesis makes Rhamnose a valuable compound in obesity studies, while Rhamnose monohydrate is also utilized in research involving Ehrlich’s solid tumors and sarcomas. -
Polysaccharide Compound
Mannan is a polysaccharide compound that primarily targets the mannose receptor (MR). It facilitates bacterial uptake and endosomal degradation, which in turn increases IL-12 production in immune cells. Mannan also enhances reactive oxygen species (ROS) generation, modulates immune responses, inhibits Aflatoxin B1-induced toxicity, and reduces lipid accumulation, making it a valuable tool in immunological research and toxicology studies. -
Flavonoid Compound
Breviscapine is a flavonoid compound that exhibits antioxidant, anti-inflammatory, anti-fibrotic, and neuroprotective activities. It effectively mitigates cerebral ischemia/reperfusion injury and vascular dementia while inhibiting the formation of postoperative abdominal adhesions. The mechanism of action is linked to the modulation of oxidative stress, inflammatory cytokines, TGF-β/Smad signaling pathways, and calcium overload in cells. Breviscapine is primarily utilized in research on cardiovascular and cerebrovascular diseases. -
Triterpenoid Saponin
Tubeimoside III is a triterpenoid saponin known for its anti-inflammatory and antitumor properties. This compound exhibits biological activity that supports research into tumorigenesis and inflammation. With an LD50 of 15 mg/kg when administered via intraperitoneal injection in ICR mice, Tubeimoside III serves as a valuable tool for investigating therapeutic interventions in cancer and inflammatory diseases. -
Flavonoid
Tribuloside is a flavonoid known for its inhibitory effects on phosphodiesterase 4 (PDE4), with an IC50 of 6 μM. It demonstrates significant antibacterial and antioxidant properties, effectively scavenging DPPH free radicals. Additionally, Tribuloside enhances melanogenesis, making it a valuable tool in the study of hypopigmentary disorders, sun protection mechanisms, and inflammatory conditions such as acute lung injury. -
Flavonoid
Saponarin is a flavonoid compound that functions primarily as an inhibitor of ERK/p38, NF-κB, and MAPK phosphorylation while activating AMPK. It exhibits significant biological activities, including antioxidant, anti-inflammatory, hepatoprotective, hypoglycemic, and hypotensive effects. Additionally, Saponarin has been shown to reduce IL-1β and COX-2 levels, making it relevant for research applications related to inflammation and metabolic disorders. Furthermore, this compound has demonstrated potential in addressing sleep disorders. -
Triterpenoid Compound
Poricoic acid B is a triterpenoid compound derived from Poria cocos, primarily known for its ability to inhibit intracellular lipid accumulation. This compound demonstrates significant effects on reducing levels of hepatocyte injury markers and suppressing the production of pro-inflammatory cytokines, including NO, TNF-α, IL-1β, and IL-6. Poricoic acid B is valuable for research applications related to metabolic dysfunction-associated fatty liver disease and various inflammatory conditions. -
Natural Product
Genistein 7-β-D-Glucuronide is a natural product known for its inhibitory effects on tubulogenesis and endothelial migration. This compound serves as a valuable tool in angiogenesis research and vascular biology studies, helping to elucidate the mechanisms underlying these critical processes. Its role in modulating cellular behaviors makes it significant for investigations in cancer biology and tissue engineering. -
Alkaloid
(±)-Glaziovine is a proaporphine alkaloid that exhibits notable anxiolytic activity. This compound is utilized in neuropharmacological research to investigate its effects on anxiety and related disorders. Its biological properties make it a valuable tool for studying the underlying mechanisms of anxiety and potential therapeutic approaches. -
Natural Product
Lamalbid is a natural product derived from Lantana montevidensis that acts primarily as an inhibitor of reactive oxygen species (ROS) generation. This compound exhibits significant antioxidant properties, making it valuable in research applications focused on oxidative stress and related cellular processes. Its potential therapeutic implications may extend to conditions associated with oxidative damage and inflammation.
