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Sennoside

Catalog No.: A29449
Anthraquinone Glycoside
Sennoside is an anthraquinone glycoside that functions as a stimulant laxative. It promotes gastrointestinal motility and secretory actions by activating 5-HT4 receptors in the myenteric plexus and inhibiting Na+/K+-ATPase activity. This compound shows potential for research applications in chronic constipation and may facilitate investigations into gastrointestinal disorders.
Sennoside 517-43-1 Anthraquinone Glycoside
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$60.00
In stock
25mg
$120.00
In stock
50mg
$185.00
In stock
100mg
$290.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSennoside is an anthraquinone glycoside that functions as a stimulant laxative. It promotes gastrointestinal motility and secretory actions by activating 5-HT4 receptors in the myenteric plexus and inhibiting Na+/K+-ATPase activity. This compound shows potential for research applications in chronic constipation and may facilitate investigations into gastrointestinal disorders.
Product Information
Catalog NumA29449
FormulaC42H38O20
Molecular Weight862.74
CAS Number517-43-1
SMILESOC[C@@H](O1)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OC2=CC=CC3=C2C(C4=C(C=C(C(O)=O)C=C4O)C3C5C6=C(C(C7=C5C=C(C(O)=O)C=C7O)=O)C(O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)=CC=C6)=O
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