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Spiramine A

Catalog No.: A48768
diterpene alkaloids
Spiramine A is a diterpene alkaloid that exhibits significant antitumor and antimicrobial properties. It effectively inhibits platelet aggregation induced by platelet-activating factor (PAF) in rabbit models, demonstrating a concentration-dependent response with an IC50 value of 6.7 μM. This compound is valuable for research applications focused on cancer biology and hematological studies.
Spiramine A 114531-28-1 diterpene alkaloids
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5mg
$605.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSpiramine A is a diterpene alkaloid that exhibits significant antitumor and antimicrobial properties. It effectively inhibits platelet aggregation induced by platelet-activating factor (PAF) in rabbit models, demonstrating a concentration-dependent response with an IC50 value of 6.7 μM. This compound is valuable for research applications focused on cancer biology and hematological studies.
Product Information
Catalog NumA48768
FormulaC24H33NO4
Molecular Weight399.52
CAS Number114531-28-1
SMILESC[C@@]12[C@]3([H])[C@@]([C@@](O4)([H])N5[C@@]1([H])OCC5)(CCC2)[C@@](CC6([H])C7=C)([H])[C@]([C@H]7OC(C)=O)(CC6)[C@@]4([H])C3
SynonymsSpiramine C acetate (ester)
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