Catalog No.
Product Name
Application
Product Information
Citations
- Stiripentol is an epilepsy drug. It has been used as co-therapy for treatment of epilepsy
- Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
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Glycogen phosphorylase (GP) inhibitor
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes. -
ECE inhibitor
(±)-WS75624B is an endothelin converting enzyme (ECE) inhibitor with an IC50 of 0.03 μg/mL. - Tepilamide fumarate (XP-23829) is an oral fumaric acid ester, acts as a prodrug of monomethyl fumarate, and is used in the research of moderate to severe chronic plaque psoriasis.
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fast-skeletal-troponin activator
Tirasemtiv amplifies skeletal muscle response to nerve activation in humans. -
immunomodulator
Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity. - Substituted piperidines-1 is a compound that can promote the release of growth hormone in humans and animals.
- Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors.
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CNT2 Inhibitor
CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2. -
ocular β-blocker
(E)-Alprenoxime is the isomer of the Alprenoxime. Alprenoxime is a site-activated ocular β-blocker. - Ombrabulin is a synthetic water-soluble analogue of combretastatin A4, derived from the South African willow bush (Combretum caffrum), with potential vascular-disrupting and antineoplastic activities.
- Teglarinad chloride, also known as GMX1777, is a water-soluble prodrug of a cyanoguanidine compound with potential antineoplastic activity. In vivo, teglarinad chloride is rapidly converted into active drug through hydrolytic cleavage of a carbonate ester bond.
- Pyronaridine Tetraphosphate is a common antimalarial agent that has been found to enhance the antitumor activity of doxorubicin against multidrug-resistant cancers K562/A02 and MCF-7/ADR.
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squalene epoxidase inhibitor
FR194738 free base is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. -
synthesized plant gowth regulator
Prohydrojasmon racemate is a synthesized plant gowth regulator. -
Neutrophil elastase inhibitor
Freselestat is a potent neutrophil elastase inhibitor. Freselestat reduces inflammatory mediators during simulated extracorporeal circulation. ONO-6818 significantly reduced interleukin 8 and C5b-9 production. ONO-6818 did not modulate changes of CD11b and L-selectin during recirculation. -
Histone-H2A peptide
Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. - Prochloraz manganese is a sterol C-14 demethylation inhibitor which impairs biosynthesis of ergosterol, an essential compound for the stability and functioning of lipoprotein membranes
- Ibutamoren, also known as MK-677 (L-163,191), is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin.
- Cardiolipin is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.
- Ceftobiprole medocaril is a fifth-generation[2] cephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus, penicillin-resistant Streptococcus pneumoniae, Pseudomonas aeruginosa, and enterococci.
- D2PM (hydrochloride) is a psychoactive designer drug that has recently been demonstrated to have toxic effects in humans.
- Lomifylline is a methylxanthine analogue which induces Ca2+-release from intracellular stores via the ryanodine receptor.
- Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.
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MC4 antagonist
SNT207858 is a 22 nM MC4 antagonist with a 170-fold selectivity vs. MC3 and a 40-fold selectivity versus MC5. - 4-Epi Minocycline is an impurity of Minocyclin, a second generation tetracycline antibiotic.
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SCD1 inhibitor
stearoyl-CoA desaturase 1 (SCD1) inhibitor. Used to selectively eliminate undifferentiated human pluripotent stem cells (hPSCs) from culture; induces ER stress, attenuates protein synthesis and induces apoptosis in hPSCs. Prevents teratoma formation in immunocompromised mice. - Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of ??-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
