Catalog No.
Product Name
Application
Product Information
Citations
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HA Peptide Segment
Influenza HA (529-537) is a peptide segment derived from positions 529-537 of hemagglutinin (HA) of the influenza A virus, consisting of the amino acid sequence IYATVAGSL. This peptide is recognized by various specificities of CD8+ cytotoxic T-lymphocyte (CTL) clones, including H1-specific, H2-specific, and H1/H2 cross-reactive responses. Influenza HA (529-537) is instrumental in studying T-cell immune specificity and has potential applications in the design of novel vaccines against influenza. -
Hemagglutinin Peptide
Influenza HA (126-138) is a peptide derived from the hemagglutinin (HA) of the influenza virus, consisting of amino acids 126-138. This peptide induces apoptosis in thymic and peripheral T-cells, making it a valuable tool for investigating T-cell responses to influenza virus infection. It serves as an important reagent for studies in immunology and virology, particularly in the development of vaccines and therapies targeting influenza. -
Peptide
PA (224-233), Influenza is a 10-amino acid peptide derived from the polymerase 2 protein of the influenza A virus. This peptide plays a crucial role in viral RNA synthesis and is important for understanding influenza pathogenesis. It can be utilized in research applications aimed at studying viral replication mechanisms, developing vaccines, and evaluating antiviral drug candidates. -
Bioactive Peptide
Influenza NP (311-325) is a bioactive peptide derived from the nucleoprotein (NP) of the influenza virus, acting as an MHC class II restricted epitope to stimulate host immune responses. This peptide is known for its ability to induce substantial interferon gamma (IFN-γ) production while avoiding activation of CD8 T cells in murine models. Its unique properties make Influenza NP (311-325) a valuable tool for research in immunology and vaccine development. -
Antiviral Peptide
Urumin is an antiviral peptide that targets the conserved stalk of H1 hemagglutinin, exhibiting potent antiviral activity against human influenza A virus. With an IC50 value of 3.8 μM against the PR8 strain, Urumin effectively inhibits the growth of both drug-sensitive and drug-resistant H1 influenza viruses. In preclinical studies, Urumin has demonstrated protective effects in naive mice against lethal influenza infection, highlighting its potential for therapeutic applications in influenza management. -
Antiviral Peptide
Cyclo(-Met-Pro) is a cyclic dipeptide comprised of methionine and proline, serving as an antiviral peptide. It demonstrates weak inhibitory activity against the influenza A virus (H3N2), achieving 2.1% inhibition at a concentration of 5 mM. This compound may be useful in studies targeting viral infections and exploring the structure-activity relationships of peptide-based antivirals. -
Antiparasitic Peptide
LL-37 FK-13 is an antimicrobial peptide that targets Trichomonas vaginalis, demonstrating significant antiparasitic activity. It has been characterized by low cytotoxicity in human fibroblasts and only mild hemolytic effects on human erythrocytes, making it a valuable candidate for research applications involving parasitic infections and related therapeutic strategies. -
Antimicrobial Peptide
Halictine 2 is an antimicrobial peptide that exhibits significant anti-parasitic activity against Leishmania species. It effectively targets both extracellular infective metacyclic promastigotes and intracellular amastigotes, making it a valuable tool for investigating leishmaniasis. This compound is suitable for research focused on the mechanisms of leishmaniasis and potential therapeutic strategies against this parasitic infection. -
Antiviral Peptide
Antiviral agent 76 is an antiviral peptide featuring azide functional groups, specifically designed to inhibit the hepatitis C virus (HCV). This compound demonstrates significant antiviral activity, making it a valuable tool for researching HCV interactions and potential therapeutic strategies. Its unique structure allows for investigations into peptide-based antiviral mechanisms and applications in virology. -
Peptide Substrate
Hepatitis C Virus S5A/5B is a synthetic peptide substrate designed to mimic the NS5A/5B junction of the nonstructural protein (NS) in the Hepatitis C virus. This peptide serves as an effective substrate for studying the activity of HCV NS3 protease, facilitating research on viral replication and proteolytic processing. It is valuable for investigations into antiviral drug development and the molecular mechanisms of HCV pathology. -
HIV-1 TAT Peptide
TAT (YGRKKRRQRRR) is a cell-penetrating peptide derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1). It enhances the solubility and yield of heterologous proteins, making it a valuable tool in research applications related to protein expression and purification. TAT's ability to facilitate cellular uptake has made it a useful reagent in studies exploring intracellular delivery mechanisms and molecular therapeutics. -
HIV-1 Polypeptide
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from residues 48-60 of the HIV-1 Tat protein, functioning as a facilitator for cellular uptake. This peptide enables the effective delivery of exogenous macromolecules into cells without causing disruption to cellular integrity. Its unique mechanism enhances research applications in drug delivery, gene therapy, and the study of intracellular processes associated with HIV-1. -
CD4 Receptor Ligand
Peptide T is an octapeptide derived from the V2 region of the HIV-1 gp120 protein. It functions as a ligand for the CD4 receptor, effectively blocking the interaction between HIV and CD4, thereby inhibiting viral entry into host cells. This compound is essential for research in HIV pathogenesis and therapeutic development targeting CD4 receptor interactions. -
HIV-1 Polypeptide
TAT (48-57) is a cell-permeable peptide derived from the HIV-1 transactivator of transcription (Tat) protein, specifically residues 48 to 57. This peptide facilitates the study of viral gene expression and replication by interacting with intracellular targets to enhance the transcriptional activity of HIV-1. TAT (48-57) is utilized in research applications focused on HIV pathogenesis, viral life cycle analysis, and the development of antiviral strategies. -
Competitive Peptide Against HiBiT
DrkBiT is a competitive peptide that targets HiBiT and is membrane-impermeable. It effectively binds to LgBiT, facilitating studies in the context of HIV-1 infection research. This peptide serves as a valuable tool for understanding viral dynamics and developing potential therapeutic strategies. -
Cell-penetrating Peptide/Delivery Carrier
TAT (47-57) GGG-Cys (Npys) is a cell-penetrating peptide that functions as an effective delivery carrier for therapeutic agents. This peptide facilitates the transport of conjugated drug molecules across biological membranes, enhancing their bioavailability. It is particularly suited for delivering MT1-MMP inhibitors and serves as a valuable tool in research on diseases linked to MT1-MMP activity, including cancer, arthritis, heart disease, and vascular disorders. -
Polypeptide
HIV-1 gag Protein p24 (194-210) is a polypeptide that serves as a critical target for immunoassays in HIV research. This peptide is essential for studying protein interactions and conducting functional analyses, particularly in the context of epitope mapping and agent development. Its application in peptide screening facilitates the identification of active peptides, aiding researchers in advancing their understanding of HIV biology and potential therapeutic strategies. -
Dipeptide
Gamma-glutamyl-beta-cyanoalanine is a dipeptide that acts as a neurotoxin, primarily found in the seeds of common vetch. This compound is of interest in biological research due to its potential effects on neurotransmission and its role in studying neurotoxic mechanisms. It may serve as a valuable tool for investigating neurodegenerative conditions and metabolic processes influenced by dipeptides. -
Peptide
Amylin (8-37), human is a peptide fragment derived from human Amylin, targeting vasodilation pathways. This compound exhibits direct vasodilatory effects in the isolated mesenteric resistance artery of rat models. As a derivative of human Amylin, it plays a role in the study of metabolic conditions associated with insulin deficiency and is relevant for research into the pathophysiology of type II diabetes mellitus. -
Angiotensin II-Related Peptide
(Des-Asp1,Ile8)-Angiotensin II is a modified peptide that targets angiotensin II receptors. It plays a crucial role in elucidating the functional dynamics of the renin-angiotensin system. This reagent is valuable for research applications involving cardiovascular physiology, hypertension, and peptide-receptor interaction studies. -
Bioactive Peptide
Biotin-Ahx-Angiotensin II human is a biochemically active peptide that targets the angiotensin II receptor. This compound plays a crucial role in regulating blood pressure and fluid balance, making it invaluable for cardiovascular research. It can be utilized in various applications, including receptor binding studies and the investigation of angiotensin signaling pathways. -
Angiogenin Peptide
Angiogenin (108-122) is a peptide derived from the angiogenin protein, known for its role in promoting angiogenesis. This peptide has been demonstrated to enhance endothelial cell proliferation and capillary tube formation, making it useful in studying vascular biology and therapeutic angiogenesis. Its applications include research in cancer, wound healing, and cardiovascular disorders, where modulation of angiogenic activity is critical. -
AR1 Receptor Inverse Agonist
Angiotensin II antipeptide is an inverse agonist of the angiotensin II type 1 (AR1) receptor. This peptide, derived from the sequence complementary to angiotensin II, demonstrates significant interaction with the AR1 receptor, altering its activity and signaling pathways. Its biological activity makes it a valuable tool in research focusing on cardiovascular physiology, hypertension, and related signaling mechanisms. -
Ang I Peptide
5-Valine-angiotensin I is an angiotensin I peptide that primarily targets the renin-angiotensin system. This compound is known to induce muscle contraction and is valuable for studying the physiological and pathological roles of angiotensin peptides. As a precursor to angiotensin II and angiotensin fragment 1-7, it plays a critical role in fluid volume regulation and aldosterone release, making it significant in cardiovascular and renal research. -
Peptide
Hippuryl-Phe-Arg-OH is a peptide substrate specifically designed for the active site of angiotensin I converting enzyme (ACE). This compound is utilized in biochemical assays to study ACE activity and inhibition, making it valuable for research in cardiovascular diseases and hypertension. Its use facilitates the investigation of the enzyme's role in the renin-angiotensin system and potential therapeutic interventions. -
Tool Peptide
Angiotensin II type 1 receptor (181-187) is a peptide derived from the second extracellular loop of the angiotensin II receptor, playing a critical role in the renin-angiotensin system. This 9-amino acid sequence acts as a key localization epitope for angiotensin II receptor autoantibodies (AT1RaAb). It is utilized in research applications to detect and quantify AT1RaAb levels in serum, facilitating studies on cardiovascular and renal pathophysiology. -
Bioactive Peptide
Renin substrate, angiotensinogen (1-14), rat is a bioactive peptide that serves as a substrate for the enzyme renin. Derived from the first 14 amino acid residues of rat angiotensinogen, this synthetic peptide is essential for studying the renin-angiotensin system. It enables researchers to investigate cardiovascular regulation and hypertension-related mechanisms. -
Angiotensin peptide
Angiotensinogen (1-13) (human) is a fragment of the renin substrate angiotensinogen, serving as a precursor for all angiotensin peptides. This bioactive peptide plays a crucial role in the renin-angiotensin system, influencing blood pressure regulation and fluid balance. It is primarily utilized in research applications focused on cardiovascular physiology, metabolism, and the pathophysiology of hypertension and related disorders. -
Brain Natriuretic Peptide
Brain Natriuretic Peptide (1-32), rat is a 32-amino acid polypeptide that primarily targets natriuretic peptide receptors in the cardiovascular system. It plays a crucial role in regulating blood pressure and fluid balance by promoting natriuresis and vasodilation. This reagent is valuable for research into heart failure, hypertension, and other cardiovascular conditions, as well as for studying the physiological effects of heart stretch on cardiac function. -
Natriuretic Peptide
C-Type Natriuretic Peptide (1-53), human, is a bioactive fragment of the natriuretic peptide family that primarily targets the regulation of electrolyte-fluid balance and vascular tone. This peptide plays a crucial role in cardiovascular homeostasis by promoting natriuresis and vasodilation. Research applications include studies on heart failure, hypertension, and other cardiovascular disorders, making it a valuable tool for elucidating the physiological and pathological roles of natriuretic peptides in the cardiovascular system. -
Cardiac Developmental Peptide
ELA-32 (human) is a potent cardiac developmental peptide that acts primarily through the G-protein-coupled apelin receptor. This peptide plays a crucial role in cardiovascular development and function, making it a valuable tool for studying cardiac biology and related disorders. ELA-32 can be utilized in research applications focused on cardiac tissue differentiation, regeneration, and signaling pathways involved in heart development. -
Cardiac developmental peptide
1-Methyl-3-phenylpropylamine is a potent cardiac developmental peptide that acts through the G-protein–coupled apelin receptor. It plays a crucial role in cardiovascular development and function, making it a valuable tool for research in heart health and related developmental biology. This compound is ideal for studies investigating the mechanisms of cardiac tissue regeneration and the effects of apelin in cardiac diseases. -
Bioactive Peptide
Apelin-16, human, bovine is a bioactive peptide that serves as an endogenous ligand for the G-protein-coupled APJ receptor. This 16-amino acid fragment of the pre-proprotein Apelin plays a significant role in various physiological processes, including regulation of blood pressure and metabolism. It is widely utilized in research focused on cardiovascular health, obesity, and neurobiology to explore its therapeutic potential and mechanisms of action. -
Neuropeptide
Neuromedin B-30 is a neuropeptide initially isolated from porcine brain and spinal cord, targeting smooth muscle tissues. Its biological activities include stimulating smooth muscle contraction, promoting local vasodilation, increasing vascular permeability, and contributing to neurogenic inflammation and hyperalgesia. Neuromedin B-30 plays a significant role in appetite regulation, thermoregulation, and behavioral stress responses, as well as modulating secretory functions in the gastrointestinal system. It is a valuable reagent for research in neurobiology, smooth muscle physiology, and inflammatory processes. -
Bioactive Peptide
Biotin-Bradykinin is a bioactive peptide that targets the bradykinin receptor, playing a significant role in modulating inflammatory responses and pain pathways. This compound is widely used in research applications related to cardiovascular studies, pain management, and cellular signaling mechanisms. Its biotin labeling facilitates easy detection and analysis in biochemical assays and cellular experiments. -
Peptide
Bradykinin (2-9) is a truncated peptide derived from the parent Bradykinin sequence, specifically produced through the cleavage by Aminopeptidase P. This peptide retains significant biological activity, including roles in vasodilation and inflammation modulation. It is utilized in research to study the physiological effects of kinins and their involvement in cardiovascular and pain pathways. -
Peptide
T-kinin (Ile-Ser-bradykinin) is a peptide that specifically targets bradykinin pathways. It demonstrates significant biological activity in modulating inflammatory responses. T-kinin is primarily utilized in research related to the mechanisms of inflammation and related signaling pathways. -
PTH2 receptor Agonist
TIP 39, Tuberoinfundibular Neuropeptide, is an endogenous agonist of the PTH2 receptor, exhibiting antihypertensive effects. This peptide selectively activates the PTH2 receptor without affecting the PTH1 receptor, leading to increased cAMP production, adenylate cyclase activation, and enhanced intracellular calcium mobilization. TIP 39 is conserved across humans, mice, and rats, making it a valuable tool for research into nociception and inflammation-related pain mechanisms. -
CGRP Agnalogue
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a CGRP analogue that targets the CGRP receptor and modulates adenylate cyclase activity. This peptide fragment, derived from the rat CGRP sequence, exhibits key biological activities associated with pain modulation and vasodilation. It is suitable for research applications studying neurogenic inflammation, cardiovascular regulation, and the pathophysiology of migraine headaches. -
Adenylate Cyclase Activator
Small Cardioactive Peptide B (SCPB) functions primarily as an adenylate cyclase activator. It significantly enhances adenylate cyclase activity in cardiac and gill tissue fractions, exhibiting EC50 values of 0.1 μM and 1.0 μM, respectively. This peptide is valuable for research exploring cardiac function and signaling pathways associated with neural regulation in various biological systems. -
VIP-secretin-like Peptide
Helodormin is a VIP-secretin-like peptide derived from the venom of the Mexican monster lizard (Heloderma suspectum). It primarily targets intracellular signaling pathways by activating adenylate cyclase, leading to various cellular responses. This reagent is valuable for investigating the evolutionary relationships and functional mechanisms within the secretin and VIP peptide families in biochemical research. -
GT1b Ligand
Tet1-Cys peptide is a specifically designed peptide that targets the GT1b ligand. It demonstrates the ability to bind to the neuronal ganglioside receptor GT1b, facilitating neuronal targeting in research applications. The inclusion of a cysteine residue in the Tet1-Cys peptide allows for efficient drug conjugation, making it a valuable tool for studies focused on drug delivery mechanisms and neuronal interactions. -
Neuron-Specific Ligand for GT1B
Tet1 peptide (HLNILSTLWKYR) is a neuron-specific ligand that selectively targets GT1B gangliosides. This peptide plays a crucial role in studies related to neuronal function and cell signaling. A commonly used variant includes a cysteine residue at the C-terminus (HLNILSTLWKYRC), facilitating peptide conjugation for drug delivery studies and enhancing research applications in neurobiology. -
cyclopentapeptide
Segetalin B is a cyclopentapeptide derived from Vaccaria segetalis, exhibiting estrogen-like activity. This compound promotes mineralization in ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and enhances levels of osteocalcin, BMP-2, alkaline phosphatase (ALP), and SIRT1 activity. Segetalin B holds potential for research into post-menopausal osteoporosis (PMOP) and related bone health studies. -
Tyrosinase Inhibitor
Decapeptide-12 is a selective inhibitor of tyrosinase, exhibiting a Kd of 61.1 μM and acting as a competitive inhibitor with an IC50 of 40 μM against mushroom tyrosinase. This decapeptide enhances the transcription of SIRT and effectively reduces melanin content in melanocytes. Decapeptide-12 is valuable for research involving melanogenesis, cellular senescence, and inflammation. -
Peptide Vaccine
Tertomotide hydrochloride is a peptide vaccine that targets the 16-amino acid sequence of human telomerase reverse transcriptase (hTERT). This compound exhibits neuroprotective properties and is primarily applied in research related to neurodegenerative conditions, including Alzheimer's disease. Its mechanism potentially aids in understanding disease pathways and developing therapeutic strategies. -
N-cadherin Agonist
N-Cadherin mimic peptide is an N-cadherin agonist that enhances N-cadherin homodimerization and β-catenin signaling. This peptide promotes early chondrogenesis and cartilage matrix production in mesenchymal stem cells (MSCs), making it a valuable tool for investigating MSC-based cartilage regeneration. Its role in promoting cell adhesion and differentiation underscores its potential in regenerative medicine research. -
Peptide Containing His-Ala-Val
HAV peptide (Ac-SHAVSS-NH2) specifically targets the E-cadherin signaling pathway and plays a crucial role in the regulation of intercellular junctions. This peptide is instrumental in various research applications focused on cellular adhesion, tissue integrity, and tumor biology. Its ability to modulate E-cadherin-mediated processes makes HAV peptide a valuable tool for investigating cellular interactions and their implications in disease models. -
Self-assembling peptides
CREKA peptide is a self-assembling peptide that selectively binds to fibrin, type IV collagen, and fibronectin. This peptide is utilized as a targeting ligand for modifying delivery carriers, facilitating the accumulation of therapeutic agents in tumor microenvironments and fibrotic tissues. By promoting drug internalization into specific target cells, such as cancer cells and activated hepatic stellate cells, CREKA peptide enhances targeted delivery efficiency, increasing local drug concentration while minimizing systemic side effects. -
Antioxidant Peptide
Tetrapeptide-1 is an antioxidant peptide that promotes the synthesis of extracellular matrix components, including collagen, elastin, and fibronectin. This activity makes Tetrapeptide-1 valuable in addressing the visible signs of skin aging, such as wrinkles and sagging. Its properties are widely utilized in cosmetic formulations aimed at improving skin texture and elasticity.
