Catalog No.
Product Name
Application
Product Information
Citations
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Collagen Mimetic Peptide
Vezocolmitide is a collagen mimetic peptide designed to simulate collagen's structural properties. This compound primarily targets pathways involved in dry eye disease (DED), making it a valuable tool for research focused on ocular surface disorders. Its ability to mimic collagen may facilitate the study of tissue repair mechanisms and the development of potential therapeutic interventions for DED. -
Hair-generating Peptide
Myristoyl pentapeptide-4 is a bioactive peptide targeting hair follicles to promote hair growth. This molecule stimulates the anagen phase of hair development, making it beneficial in cosmetic applications aimed at enhancing hair density and health. Its activity supports research in both dermatology and cosmetic science, particularly in the formulation of hair restoration products. -
Cyclic Dipeptide
Cyclo(Ala-Hyp) is a cyclic dipeptide that targets collagen synthesis and hydroxyproline metabolism. This compound exhibits notable biological activity, demonstrating a significantly higher area under the curve (AUC0-6h) of 2.350 μg/mL·h compared to traditional collagen oligopeptides. Research applications for Cyclo(Ala-Hyp) include investigations into its protective effects on liver and kidney functions, as well as its potential benefits in skin care and joint health. -
βARK Substrate
RESA peptide is a substrate for β-adrenergic receptor kinase (βARK) that facilitates βARK-mediated phosphorylation. Its N-terminal acidic residues enhance both the efficiency of phosphorylation and the binding affinity to the kinase. This peptide is valuable for studies investigating βARK signaling pathways and the regulation of adrenergic receptors, contributing to the understanding of cardiac function and other physiological processes. -
α1 Adrenergic Receptor Inhibitor
Conopeptide rho-TIA is a peptide originating from the venom of the predatory sea snail Conus tulipa, serving as a highly selective noncompetitive inhibitor of the human α1B-adrenergic receptor. It also acts as a competitive inhibitor for both the α1A- and α1D-adrenergic receptors. By selectively binding to these receptor subtypes, conopeptide rho-TIA offers valuable insights for the development of novel, subtype-selective α1-adrenergic receptor therapies. Its unique mechanism of action makes it a potent tool for cardiovascular and pharmacological research. -
Peptide
G-Protein antagonist peptide is a peptide that inhibits G protein binding to its receptors. This compound competitively and reversibly obstructs M2 muscarinic receptor activation of Gi or Go and impedes Gs activation by β-adrenoceptors. Its biological activity makes it a valuable tool for studies involving G protein-coupled receptors and their signaling pathways, contributing to research in pharmacology and neurobiology. -
Adrenergic Receptor Agonist
Prenalterol hydrochloride is a selective partial agonist of the β1-adrenergic receptor, known for its positive inotropic effects. This compound has demonstrated significant efficacy in the management of acute heart failure, low output syndrome following myocardial infarction, and shock. Additionally, it has been used to alleviate orthostatic hypotension associated with Shy-Drager syndrome, making it a valuable reagent for cardiovascular research. -
Anti-aging Peptide
Palmitoyl pentapeptide 4 is a bioactive peptide that primarily targets skin aging mechanisms. It promotes collagen synthesis and enhances skin elasticity, leading to visible anti-aging effects. This peptide is widely utilized in cosmetic formulations aimed at reducing the appearance of fine lines and wrinkles, making it a valuable reagent in dermatological research and cosmetic development. -
Collagen Mimetic Peptide
P15 is a collagen mimetic peptide characterized by the sequence GTPGPQGIAGQRGVV, designed to replicate the cell-binding domain of human type I collagen. It effectively promotes the adhesion, proliferation, and differentiation of osteoblasts, making it a valuable tool in bone regeneration research. Biomaterials modified with P15 are utilized for studies aimed at enhancing bone healing and tissue engineering applications. -
COLIV-peptide
COLIV-peptide is a specific binding peptide that targets Collagen IV, a critical non-cellular component found in atherosclerotic plaques. This peptide facilitates the investigation of atherosclerosis by allowing researchers to study the role of Collagen IV in plaque formation and progression. COLIV-peptide can be utilized in various applications, including diagnostics and therapeutic research related to cardiovascular diseases. -
Dynamin Inhibitor
DynaMin inhibitory peptide, myristoylated is a specific inhibitor of dynamin, targeting the interaction between dynamin and amphiphysin. This membrane-permeant peptide effectively disrupts endocytosis processes, making it valuable for studying vesicle trafficking and membrane dynamics in various cellular contexts. Its ability to inhibit endocytic pathways allows for investigations into related cellular mechanisms and potential therapeutic applications in modulating cellular uptake processes. -
Drp1 Inhibitor
Drp1 peptide inhibitor P110 is a selective inhibitor of Dynamin-related protein 1 (Drp1), targeting mitochondrial dynamics. This compound exhibits neuroprotective effects by inhibiting Drp1 activation, preventing MPTP-induced mitochondrial translocation, and mitigating dopaminergic neuron loss along with associated behavioral deficits. Research applications include studies on Alzheimer's disease, as well as models of Huntington's disease, cerebral ischemic injury, and myocardial infarction, where P110 has demonstrated the ability to reduce mitochondrial damage and alleviate organ injury. -
Peptide
ACT1 is a peptide that enhances the stability and activity of endogenous connexin 43 (Cx43) at gap junctions. This stabilization promotes intercellular communication in breast cancer cells, thereby enhancing the efficacy of therapeutic agents such as Tamoxifen and Lapatinib. ACT1 serves as a valuable tool in research focused on breast cancer mechanisms and treatment strategies. -
Bioactive Peptide
Connexin mimetic peptide 40GAP27 is a bioactive peptide that targets the gap junction connexin 40 (Cx40). It is primarily utilized to study the effects of oxidative stress on gap junction intercellular communication. Research has demonstrated that 40GAP27 can attenuate endothelium-dependent subintimal smooth muscle hyperpolarization, providing insights into vascular function and pathology. This peptide is a valuable tool for investigations into cardiovascular health and the role of gap junctions in cellular signaling. -
Integrin Binding Peptide
GRGDSPK is an integrin binding peptide that functions as a competitive and reversible inhibitor of integrin-fibronectin interactions. This peptide is instrumental in elucidating the roles of integrins in bone formation and resorption, making it valuable for research in cell adhesion and tissue engineering. Its ability to modulate integrin activity enables studies on cellular responses in various biological contexts. -
Peptide
REDV is a peptide derived from the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. It effectively mediates cell adhesion by binding to the integrin α4β1, facilitating interactions with plasma fibronectin. This peptide is widely utilized in research applications focused on cell adhesion mechanisms and the effects of gene vectors incorporating REDV on cellular behavior. -
Collagen Receptor Antagonist
α2β1 Integrin Ligand Peptide serves as an antagonist of the α2β1 integrin receptor, which is essential for mediating cellular responses to extracellular matrix components, specifically collagen. This peptide disrupts integrin signaling, making it a valuable tool for exploring collagen-related pathways and studying cellular adhesion processes. Its applications include research in fibrosis, tissue remodeling, and other disorders where integrin-collagen interactions are pivotal. -
Peptide
Integrin Binding Peptide is a derived peptide that targets integrins, facilitating cell adhesion and migration. This peptide is primarily utilized in biomaterials research, specifically in the preparation of polyethylene glycol (PEG) hydrogels, enhancing their biocompatibility and functionality for tissue engineering applications. Its ability to promote cellular interactions makes it a valuable tool in studies involving cell behavior and manipulation. -
Collagen-mimetic Sequence
GFOGER peptide is a collagen-mimetic sequence that functions primarily as a ligand for integrins α2β1, α11β1, and α1β1, promoting integrin-mediated cell adhesion to collagen. This peptide triggers signaling pathways through the α2β1 integrin receptor, facilitating osteoblast differentiation and enhancing bone formation, particularly in challenging femoral defects. GFOGER peptide is suitable for incorporation into biomaterials such as hydrogels and 3D bioinks, making it a valuable tool for tissue engineering applications focused on bone regeneration. Additionally, it can be passively adsorbed onto polymer scaffolds for effective cell-free and growth factor-free bone formation strategies. -
Integrin
G4RGDSP is an integrin-binding peptide designed to specifically interact with integrin receptors, facilitating improved cell adhesion and viability. Coupled with alginate, this peptide enhances chondrocyte delivery within 3D printed scaffolds. G4RGDSP is valuable for research applications involving tissue engineering and regenerative medicine, particularly in the formulation of bioactive materials that support cell proliferation and structural integrity within three-dimensional constructs. -
cRGDfK Peptide
cRGDfK-thioacetyl ester is a bioactive polypeptide that selectively targets integrins. This compound has significant applications in cancer research, particularly as a modifying agent for near-infrared (NIR) fluorescent probes used in imaging studies. The cRGDfK peptide's ability to enhance targeting efficacy makes it a valuable tool for investigating integrin-mediated processes in oncology. -
Peptides
E(c(RGDfK))2 is an αvβ3 integrin-specific binding peptide, designed for targeted therapy in oncology research. This agent demonstrates enhanced uptake in human ovarian cancer OVCAR-3 xenograft tumors, making it a valuable tool for studying tumor localization and targeting strategies in cancer treatment. Its specificity for integrin receptors facilitates investigations into tumor biology and the development of targeted therapies. -
Adhesion Peptide
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is a cell adhesion peptide that targets the α2bβ3 integrin, enhancing cellular adhesion processes. This peptide, derived from the carboxyl-terminal sequence of the fibrinogen γ-chain, serves as a potent ligand for smooth muscle cells (SMCs). Its biological activity makes it valuable for research applications in cell adhesion studies, tissue engineering, and vascular biology. -
Fibrinogen Binding Inhibitor Peptide
Fibrinogen Binding Inhibitor Peptide is a dodecapeptide derived from the carboxy-terminal sequence of the fibrinogen γ-chain (γ400-411). It specifically targets the binding site for activated glycoprotein (GP) IIb/IIIa, playing a crucial role in inhibiting fibrinogen interactions. This peptide is valuable for research applications focused on thrombosis, platelet aggregation, and cardiovascular disease mechanisms. -
αvβ3 Targeting Peptide
Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) targets the integrin αvβ3 and serves as a cyclic RGD peptide. This compound exhibits cell adhesion and migration activity, making it a valuable tool for modifying drug-loaded nanoparticles in therapeutic applications. It is widely utilized in cancer research, particularly for studies related to pancreatic cancer, enabling exploration of integrin-mediated processes in tumor biology. -
Inhibitory Peptide
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) functions as an inhibitory peptide targeting the α5β1 integrin. This synthetic ligand effectively competes with invasin for binding to the α5β1 integrin on Caco-2 cells, thereby disrupting cell adhesion and signaling processes. Its application is significant in studying integrin-related interactions and cellular behaviors, making it a valuable tool in cancer and cell biology research. -
RGD-related Peptide
Arg-Gly-Glu-Ser is an RGD-related peptide that serves as a negative control for studies involving Arg-Gly-Asp-Ser. This polypeptide is commonly utilized in research applications focused on integrin binding and cellular adhesion processes, helping to elucidate the functional roles of RGD sequences in various biological contexts. Its distinct activity allows for the differentiation between specific and non-specific interactions in cellular assays. -
Fibronectin Peptide Fragment
EILEVPST is a recombinant peptide fragment derived from human fibronectin, designed to specifically target α4 integrin. This low-molecular-weight peptide facilitates cell type-specific adhesion, making it a valuable tool in cellular and molecular biology research. EILEVPST is particularly relevant for studies investigating thrombogenesis and related vascular processes. -
VLA-3 Blocking Peptide
LXY3 is a VLA-3-blocking peptide that inhibits the interaction between the integrin α3β1 (VLA-3) present on neutrophils and laminin in the basement membrane. By obstructing this interaction, LXY3 effectively prevents neutrophil migration across the tumor vascular basement membrane barrier, thereby mitigating neutrophil-mediated nanoparticle release from perivascular pools into the tumor interstitium. This peptide is particularly useful in targeted imaging studies related to breast cancer. -
Peptide
GREDVGC is a peptide that functions by mimicking vascular cell adhesion molecule 1 (VCAM-1) to facilitate binding to integrin α4β1. This interaction plays a crucial role in cell adhesion and migration processes, making GREDVGC a valuable tool for cancer research and studies involving tumor metastasis. Its utility extends to investigating the physiological and pathological roles of integrin-mediated signaling pathways. -
Anti-adhesive Peptide
FNIII14 is an anti-adhesive peptide derived from the 14th fibronectin type III repeat. It effectively inhibits cell adhesion to the extracellular matrix by inducing a conformational change in β1-integrin, shifting it from an active to an inactive state and blocking integrin-mediated signaling. FNIII14 demonstrates anti-fibrotic and anti-cancer properties, making it a valuable tool for research in areas such as metabolic diseases, organ fibrosis, and malignant tumors. -
Cyclic Peptide
Relitegatide is a cyclic peptide that selectively targets the αvβ6 integrin, known for its involvement in cellular processes such as adhesion, migration, and signaling. This compound exhibits potential utility in research related to fibrosis and cancer progression, facilitating studies of integrin-mediated pathways and their implications in disease models. Additionally, it can be utilized in the synthesis of Relitegatide brexetan for further applications in scientific investigations. -
Cyclic RGD Peptide
Cyclo(GRGDSPA) is a cyclic RGD peptide that selectively targets the αvβ3 integrin. It exhibits significant biological activity by inhibiting colony formation in mice injected with B16-FE7 melanoma cells. This compound is valuable for research applications focused on melanoma biology and integrin-mediated signaling pathways. -
Fibronectin Decapeptide
RGDSPASSKP is a fibronectin decapeptide that contains the integrin-binding sequence RGDS. This compound is known for its ability to promote cell adhesion and migration through interaction with integrins, making it valuable in studies of cellular processes such as wound healing, tissue engineering, and cancer metastasis. Its applications extend to investigating the role of extracellular matrix components in cell behavior and signaling pathways. -
αvβ3 Inhibiting Peptide
G-Pen-GRGDSPCA is an αvβ3-inhibiting peptide designed to modulate cellular interactions with the extracellular matrix. This compound effectively limits neointimal hyperplasia and lumen stenosis following vascular injury, while also regulating the migration and proliferation of smooth muscle cells. G-Pen-GRGDSPCA is a valuable tool for investigating the mechanisms underlying vascular injury repair and cellular response in cardiovascular research. -
Antitumor Agent
Fibronectin CS1 Peptide is an antitumor agent that targets cell adhesion processes involved in tumor progression. By lacking the Arg-Gly-Asp sequence, this peptide effectively inhibits tumor metastasis in both spontaneous and experimental models. Its unique mechanism makes it a valuable tool for research focused on understanding and combating metastatic cancer. -
Integrin Antagonist
Cyclopeptide-5 is an integrin antagonist specifically targeting the αvβ3 integrin. It demonstrates the ability to ameliorate PAF-induced adhesion of sickle red blood cells and enhance blood flow dynamics following capillary obstruction. Additionally, Cyclopeptide-5 exhibits cytotoxic effects, making it a valuable compound for research applications in vascular biology and pathophysiology. -
RGT Peptide
Myr-RGT is a myristoylated RGT peptide that targets integrin β3. It effectively inhibits extracellular signaling pathways associated with integrin β3, making it a valuable reagent for studying atherosclerosis and related cardiovascular conditions. Myr-RGT may provide insights into the molecular mechanisms underlying integrin-mediated cellular processes and contribute to the development of therapeutic strategies. -
RGD based Peptide
GR83895 is an RGD-based peptide that inhibits ADP-induced platelet aggregation in human gel-filtered platelets, with an IC50 of 0.9 μM. This compound is valuable for research exploring platelet function and thrombosis. Its ability to modulate platelet aggregation makes it a useful tool in studies related to cardiovascular diseases and hemostasis. -
Integrin-binding Peptide
Ventegatide is an integrin-binding peptide that specifically targets integrin proteins involved in cell adhesion and signaling. This compound exhibits significant biological activity in modulating extracellular matrix interactions, making it a valuable tool for investigating the pathophysiology of osteoarthritis. Researchers can utilize Ventegatide for studies focused on cartilage repair and synovial inflammation, contributing to the understanding of joint diseases and potential therapeutic strategies. -
PAR Activating Peptide
TRAP-14 amide is a PAR-activating peptide that acts as an agonist with an EC50 of 24 μM. It significantly promotes platelet aggregation through ADP- and MMP-2-dependent pathways, demonstrating resistance to inhibition by Aspirin. Additionally, TRAP-14 amide enhances the surface expression of glycoprotein Ib and GPIIb/IIIa while facilitating ADP release, making it a valuable tool for research into platelet function and thrombus formation. -
Glycoprotein IIb/IIIa Peptide Antagonist
RPR-109891 is an orally active glycoprotein IIb/IIIa peptide antagonist that functions by inhibiting platelet aggregation. This compound has demonstrated the ability to decrease platelet count and shorten platelet survival time. RPR-109891 is valuable for research into cardiovascular diseases, including myocardial infarction, by providing insights into platelet function and thrombotic processes. -
MARCKS Inhibitor
MANS peptide is an inhibitor of myristoylated alanine-rich C kinase substrate (MARCKS), which functions by competing with MARCKS for membrane binding in cellular environments. This competitive inhibition effectively reduces the stimulation of mucin secretion and can impede processes related to tumor metastasis. MANS peptide is valuable for research investigating cellular signaling pathways and the role of MARCKS in cancer progression. -
Non-MARCKS Effector Peptide
MPSD control peptide is a non-MARCKS effector peptide designed to serve as a control for the MPSD peptide. This 25-amino acid peptide is derived from the effector domain sequence of the myristoylated alanine-rich C-kinase substrate (MARCKS), enabling it to interact with membrane curvature and phosphatidylserine. MPSD control peptide can be utilized as a biological probe to investigate membrane shape and lipid composition, providing valuable insights for cellular and biochemical research applications.
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Control Peptide for MPSD
Ala-MPSD is a control peptide for the study of the multidomain protein MPSD. This variant features substitutions of the four serine residues with alanine, allowing researchers to investigate the functional consequences of serine modifications. Ala-MPSD is primarily utilized in biochemical assays and structural studies to elucidate the role of serine phosphorylation in MPSD-related pathways. -
smMLCK Inhibitor
smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK) that functions by mimicking the substrate and competitively inhibiting substrate binding. This mechanism disrupts kinase activity, preventing phosphorylation of the myosin light chain and subsequently inhibiting muscle contraction. It is a valuable tool for studying smooth muscle function and exploring therapeutic strategies for related disorders. -
Peptide Substrate of MLCK
Kemptamide is a peptide substrate for myosin light-chain kinase (MLCK), comprised of a 13 amino acid sequence corresponding to residues 11-23 of gizzard light chain. This compound plays a crucial role in studies investigating MLCK activity and myosin phosphorylation. Its applications include exploring muscle contraction mechanisms and intracellular signaling pathways relevant to various physiological and pathological conditions. -
Active Substrate
AMARA peptide is an active substrate for Salt-Inducible Kinases (SIKs) and AMP-activated Protein Kinase (AMPK). This peptide serves as a crucial tool for studying the phosphorylation and regulation of these kinases, facilitating research in metabolic pathways and energy homeostasis. Its use in biochemical assays can aid in understanding the molecular mechanisms of various diseases related to metabolic dysfunction. -
Antimicrobial Peptide
Peptide 5f is an antimicrobial peptide derived from wasp venom, targeting bacterial and fungal pathogens. It exhibits significant antimicrobial activity while demonstrating minimal hemolytic effects on human red blood cells. This peptide serves as a valuable tool for researchers investigating antimicrobial mechanisms and potential therapeutic applications in combating infectious diseases. -
Antimicrobial Peptide
G(IIKK)3I-NH2 is an antimicrobial peptide that targets bacterial membranes, exhibiting significant antibacterial properties against both Gram-negative and Gram-positive bacteria. This peptide demonstrates low toxicity in primary cells and mouse models, making it a suitable candidate for therapeutic applications. Additionally, G(IIKK)3I-NH2 is noted for its ability to resist induction of bacterial resistance, positioning it as a valuable reagent in the research of anti-infection agents.
