Catalog No.
Product Name
Application
Product Information
Citations
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VLA-3 Blocking Peptide
LXY3 is a VLA-3-blocking peptide that inhibits the interaction between the integrin α3β1 (VLA-3) present on neutrophils and laminin in the basement membrane. By obstructing this interaction, LXY3 effectively prevents neutrophil migration across the tumor vascular basement membrane barrier, thereby mitigating neutrophil-mediated nanoparticle release from perivascular pools into the tumor interstitium. This peptide is particularly useful in targeted imaging studies related to breast cancer. -
Peptide
GREDVGC is a peptide that functions by mimicking vascular cell adhesion molecule 1 (VCAM-1) to facilitate binding to integrin α4β1. This interaction plays a crucial role in cell adhesion and migration processes, making GREDVGC a valuable tool for cancer research and studies involving tumor metastasis. Its utility extends to investigating the physiological and pathological roles of integrin-mediated signaling pathways. -
Anti-adhesive Peptide
FNIII14 is an anti-adhesive peptide derived from the 14th fibronectin type III repeat. It effectively inhibits cell adhesion to the extracellular matrix by inducing a conformational change in β1-integrin, shifting it from an active to an inactive state and blocking integrin-mediated signaling. FNIII14 demonstrates anti-fibrotic and anti-cancer properties, making it a valuable tool for research in areas such as metabolic diseases, organ fibrosis, and malignant tumors. -
Cyclic Peptide
Relitegatide is a cyclic peptide that selectively targets the αvβ6 integrin, known for its involvement in cellular processes such as adhesion, migration, and signaling. This compound exhibits potential utility in research related to fibrosis and cancer progression, facilitating studies of integrin-mediated pathways and their implications in disease models. Additionally, it can be utilized in the synthesis of Relitegatide brexetan for further applications in scientific investigations. -
Cyclic RGD Peptide
Cyclo(GRGDSPA) is a cyclic RGD peptide that selectively targets the αvβ3 integrin. It exhibits significant biological activity by inhibiting colony formation in mice injected with B16-FE7 melanoma cells. This compound is valuable for research applications focused on melanoma biology and integrin-mediated signaling pathways. -
Fibronectin Decapeptide
RGDSPASSKP is a fibronectin decapeptide that contains the integrin-binding sequence RGDS. This compound is known for its ability to promote cell adhesion and migration through interaction with integrins, making it valuable in studies of cellular processes such as wound healing, tissue engineering, and cancer metastasis. Its applications extend to investigating the role of extracellular matrix components in cell behavior and signaling pathways. -
αvβ3 Inhibiting Peptide
G-Pen-GRGDSPCA is an αvβ3-inhibiting peptide designed to modulate cellular interactions with the extracellular matrix. This compound effectively limits neointimal hyperplasia and lumen stenosis following vascular injury, while also regulating the migration and proliferation of smooth muscle cells. G-Pen-GRGDSPCA is a valuable tool for investigating the mechanisms underlying vascular injury repair and cellular response in cardiovascular research. -
Antitumor Agent
Fibronectin CS1 Peptide is an antitumor agent that targets cell adhesion processes involved in tumor progression. By lacking the Arg-Gly-Asp sequence, this peptide effectively inhibits tumor metastasis in both spontaneous and experimental models. Its unique mechanism makes it a valuable tool for research focused on understanding and combating metastatic cancer. -
Integrin Antagonist
Cyclopeptide-5 is an integrin antagonist specifically targeting the αvβ3 integrin. It demonstrates the ability to ameliorate PAF-induced adhesion of sickle red blood cells and enhance blood flow dynamics following capillary obstruction. Additionally, Cyclopeptide-5 exhibits cytotoxic effects, making it a valuable compound for research applications in vascular biology and pathophysiology. -
RGT Peptide
Myr-RGT is a myristoylated RGT peptide that targets integrin β3. It effectively inhibits extracellular signaling pathways associated with integrin β3, making it a valuable reagent for studying atherosclerosis and related cardiovascular conditions. Myr-RGT may provide insights into the molecular mechanisms underlying integrin-mediated cellular processes and contribute to the development of therapeutic strategies. -
RGD based Peptide
GR83895 is an RGD-based peptide that inhibits ADP-induced platelet aggregation in human gel-filtered platelets, with an IC50 of 0.9 μM. This compound is valuable for research exploring platelet function and thrombosis. Its ability to modulate platelet aggregation makes it a useful tool in studies related to cardiovascular diseases and hemostasis. -
Integrin-binding Peptide
Ventegatide is an integrin-binding peptide that specifically targets integrin proteins involved in cell adhesion and signaling. This compound exhibits significant biological activity in modulating extracellular matrix interactions, making it a valuable tool for investigating the pathophysiology of osteoarthritis. Researchers can utilize Ventegatide for studies focused on cartilage repair and synovial inflammation, contributing to the understanding of joint diseases and potential therapeutic strategies. -
PAR Activating Peptide
TRAP-14 amide is a PAR-activating peptide that acts as an agonist with an EC50 of 24 μM. It significantly promotes platelet aggregation through ADP- and MMP-2-dependent pathways, demonstrating resistance to inhibition by Aspirin. Additionally, TRAP-14 amide enhances the surface expression of glycoprotein Ib and GPIIb/IIIa while facilitating ADP release, making it a valuable tool for research into platelet function and thrombus formation. -
Glycoprotein IIb/IIIa Peptide Antagonist
RPR-109891 is an orally active glycoprotein IIb/IIIa peptide antagonist that functions by inhibiting platelet aggregation. This compound has demonstrated the ability to decrease platelet count and shorten platelet survival time. RPR-109891 is valuable for research into cardiovascular diseases, including myocardial infarction, by providing insights into platelet function and thrombotic processes. -
MARCKS Inhibitor
MANS peptide is an inhibitor of myristoylated alanine-rich C kinase substrate (MARCKS), which functions by competing with MARCKS for membrane binding in cellular environments. This competitive inhibition effectively reduces the stimulation of mucin secretion and can impede processes related to tumor metastasis. MANS peptide is valuable for research investigating cellular signaling pathways and the role of MARCKS in cancer progression. -
Non-MARCKS Effector Peptide
MPSD control peptide is a non-MARCKS effector peptide designed to serve as a control for the MPSD peptide. This 25-amino acid peptide is derived from the effector domain sequence of the myristoylated alanine-rich C-kinase substrate (MARCKS), enabling it to interact with membrane curvature and phosphatidylserine. MPSD control peptide can be utilized as a biological probe to investigate membrane shape and lipid composition, providing valuable insights for cellular and biochemical research applications.
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Control Peptide for MPSD
Ala-MPSD is a control peptide for the study of the multidomain protein MPSD. This variant features substitutions of the four serine residues with alanine, allowing researchers to investigate the functional consequences of serine modifications. Ala-MPSD is primarily utilized in biochemical assays and structural studies to elucidate the role of serine phosphorylation in MPSD-related pathways. -
smMLCK Inhibitor
smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK) that functions by mimicking the substrate and competitively inhibiting substrate binding. This mechanism disrupts kinase activity, preventing phosphorylation of the myosin light chain and subsequently inhibiting muscle contraction. It is a valuable tool for studying smooth muscle function and exploring therapeutic strategies for related disorders. -
Peptide Substrate of MLCK
Kemptamide is a peptide substrate for myosin light-chain kinase (MLCK), comprised of a 13 amino acid sequence corresponding to residues 11-23 of gizzard light chain. This compound plays a crucial role in studies investigating MLCK activity and myosin phosphorylation. Its applications include exploring muscle contraction mechanisms and intracellular signaling pathways relevant to various physiological and pathological conditions. -
Active Substrate
AMARA peptide is an active substrate for Salt-Inducible Kinases (SIKs) and AMP-activated Protein Kinase (AMPK). This peptide serves as a crucial tool for studying the phosphorylation and regulation of these kinases, facilitating research in metabolic pathways and energy homeostasis. Its use in biochemical assays can aid in understanding the molecular mechanisms of various diseases related to metabolic dysfunction. -
Antimicrobial Peptide
Peptide 5f is an antimicrobial peptide derived from wasp venom, targeting bacterial and fungal pathogens. It exhibits significant antimicrobial activity while demonstrating minimal hemolytic effects on human red blood cells. This peptide serves as a valuable tool for researchers investigating antimicrobial mechanisms and potential therapeutic applications in combating infectious diseases. -
Antimicrobial Peptide
G(IIKK)3I-NH2 is an antimicrobial peptide that targets bacterial membranes, exhibiting significant antibacterial properties against both Gram-negative and Gram-positive bacteria. This peptide demonstrates low toxicity in primary cells and mouse models, making it a suitable candidate for therapeutic applications. Additionally, G(IIKK)3I-NH2 is noted for its ability to resist induction of bacterial resistance, positioning it as a valuable reagent in the research of anti-infection agents. -
Cell Penetrating Peptide
(KFF)3K is a cell-penetrating peptide designed to enhance the delivery of antibiotics by disrupting bacterial outer membranes. This peptide exhibits significant antimicrobial properties and can be incorporated into hydrocarbon scaffolds to improve its efficacy. (KFF)3K is ideal for researching and developing new antimicrobial agents. -
GarKS Peptide
Garvicin KS, GakA is a 34-amino acid peptide designed to inhibit the viability and proliferation of fibroblasts. This peptide, part of the garvicin KS bacteriocin family, functions alongside GakB and GakC to enhance antimicrobial efficacy. Notably, Garvicin KS, GakA demonstrates potency against Methicillin-Sensitive Staphylococcus Aureus (MSSA), exhibiting minimum inhibitory concentration (MIC) values that rank GakB as the most effective, followed by GakC and GakA. This peptide's stability and biological activity make it valuable for research in antimicrobial and fibroblast-related applications. -
Antimicrobial Peptide
HR1 is an antimicrobial peptide that functions as a mastoid protease, increasing the permeability of human erythrocyte membranes. It effectively induces cytoplasmic membrane permeation in both bacteria and mast cells, making it a valuable reagent for studies in microbial resistance and immune response research. Applications of HR1 include investigations into membrane disruption mechanisms and the development of novel antimicrobial therapies. -
Antimicrobial/Antitumor Peptide
Crotalicidin is an antimicrobial and anti-tumor peptide derived from rattlesnake venom, targeting Gram-negative bacteria and tumor cells. This peptide exhibits significant inhibitory activity against microbial infections and cancerous cell proliferation. Crotalicidin is valuable for research applications focused on exploring novel antimicrobial strategies and cancer therapeutics. -
Antimicrobial Peptide
Temporin B is an antimicrobial peptide primarily targeting Gram-positive bacteria. It exhibits potent bactericidal activity, making it a valuable tool for research in antimicrobial resistance and the development of new antibiotics. Due to its lower efficacy against Gram-negative bacteria, Temporin B serves as an important compound for studies focused on Gram-positive infectious agents. -
Antibacterial Peptide
LDKA is a helical membrane-active antibacterial peptide that primarily disrupts bacterial membranes. This compound demonstrates significant antibacterial activity against both Gram-positive bacteria, such as Staphylococcus aureus, and Gram-negative bacteria, including Escherichia coli and Pseudomonas aeruginosa, in nutrient-rich environments. The minimum inhibitory concentrations (MICs) for LDKA range from 10 to 70 μM, making it a valuable tool for research in antibacterial therapeutic development. -
Immunodominant CEF Controlling Peptide
EBV BZLF1 (190-197) is an immunodominant peptide derived from the Epstein-Barr virus (EBV) that specifically targets CD8+ T cells. It stimulates the release of interferon-gamma (IFNg), initiating cytotoxic T lymphocyte (CTL) responses. This peptide exhibits cross-reactivity with similar sequences from both host self-proteins and bacterial proteins, making it valuable for studying autoimmune diseases and the immune response to viral infections. -
Bioactive Peptide
Pyrrhocoricin is a bioactive peptide with antimicrobial activity primarily against Gram-negative bacteria. This compound exhibits potential as an antibiotic agent, making it valuable for research in infectious diseases and antibiotic development. Its unique mechanism of action and specificity offer insights into peptide-based therapeutics and bacterial resistance studies. -
Antimicrobial Peptide
Retrocyclin-2 is an antimicrobial peptide primarily targeting viral infections. It exhibits potent activity against human immunodeficiency virus (HIV), influenza A, and herpes simplex virus (HSV). This compound is valuable for research applications focused on antiviral therapeutics and the study of peptide-based resistance mechanisms. -
Plant Peptide
Mram 8 is a cyclotide derived from Viola philippica, a member of the Violaceae family. This plant peptide exhibits unique structural properties that contribute to its stability and biological activity. Mram 8 is of particular interest for research applications involving peptide synthesis, functional studies of plant-derived compounds, and exploration of potential therapeutic uses in agriculture and biotechnology. -
Skin Repair Peptide
Oligopeptide-20 is a bioactive peptide known for its skin repair properties, primarily targeting cellular regeneration and enhancing skin barrier function. It promotes the synthesis of key extracellular matrix components, contributing to improved skin texture and elasticity. This peptide is commonly utilized in cosmetic formulations aimed at skin rejuvenation and anti-aging applications. -
Cell-penetrating Peptide/Proteasome Inhibitor
Octaarginine is a cell-penetrating peptide and potent proteasome inhibitor. It exhibits mixed-type inhibition against the chymotrypsin-like, caspase-like, and trypsin-like activities of the 20S proteasome while displaying reduced efficacy against the 26S proteasome. This compound facilitates the accumulation of ubiquitin-conjugated proteins and promotes HSPG-dependent cellular internalization through macropinocytosis, thereby enhancing the uptake of liposomal cargo and gene delivery. Octaarginine is valuable for research related to cervix carcinoma, collagen antibody-induced arthritis, and bacterial infections. -
Antimicrobial Peptide
HPA3NT3-A2 is an analogue of the host defense peptide HP (2-20), targeting bacterial membrane integrity. This antimicrobial peptide demonstrates significant activity against multi-drug resistant bacterial strains, making it a valuable tool for research in antimicrobial resistance mechanisms and peptide-based therapeutics. Its efficacy in combating resistant pathogens positions it as a critical compound for studies aimed at developing novel antimicrobial agents. -
Bacterial Peptide Deformylase Inhibitor
Lanopepden camsylate is a high-affinity inhibitor of bacterial peptide deformylase, an enzyme critical for protein maturation in bacteria. This compound exhibits potent activity against bacterial infections by disrupting essential protein processing. Lanopepden camsylate is primarily utilized in research applications focused on the development of new antibacterial agents and the study of bacterial pathogenicity. -
Antimicrobial Peptide
AMPR-22 is an antimicrobial peptide that interacts with bacterial membranes to induce membrane permeabilization. This compound exhibits significant antimicrobial activity, effectively targeting multidrug-resistant (MDR) strains in preclinical murine models of sepsis. AMPR-22 is a valuable tool for researchers investigating novel antimicrobial agents and strategies to combat antibiotic resistance. -
Antimicrobial Peptide
GLK-19 is an antimicrobial peptide that exerts its activity against Escherichia coli, exhibiting a minimum inhibitory concentration (MIC) of 10 μM. This compound demonstrates significant antibacterial properties, making it valuable for research applications focused on antimicrobial resistance and peptide therapeutics. Its ability to selectively target bacterial cells positions GLK-19 as a promising candidate for further studies in infection control and antibiotic development. -
Antimicrobial Peptide
Pleurocidin is an antimicrobial peptide that exerts its effects by disrupting bacterial cell membranes. Derived from the skin secretions of Winter Flounder, it exhibits significant antibacterial activity against a range of pathogenic microorganisms. This compound is useful in research applications focused on developing novel antimicrobial agents and studying host defense mechanisms. -
Antimicrobial Peptide
Distinctin is an antimicrobial peptide extracted from frog skin, exhibiting potent antibacterial activity against pathogens such as Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli, with minimum inhibitory concentrations (MIC) of 14.5 μM and 28.0 μM. This compound plays a crucial role in studies focused on antimicrobial resistance and therapeutic applications in treating bacterial infections. Its unique mechanism of action enhances its utility in various microbiological and biomedical research endeavors. -
Antibacterial Peptide
Hc-CATH is an antibacterial peptide derived from sea snake cathelicidin, exhibiting broad-spectrum antimicrobial activity. It effectively inhibits the growth of Shigella dysenteriae and Klebsiella pneumoniae, with minimum inhibitory concentrations (MIC) ranging from 0.16 mM to 20.67 mM. Additionally, Hc-CATH demonstrates anti-inflammatory properties, making it a valuable tool for research in the fields of infectious disease and inflammation. -
Dipeptide Probe
EDA-DA is a dipeptide probe designed to label peptidoglycan (PG) in bacterial cell walls. Peptidoglycan is crucial for bacterial division, structural integrity, and maintaining osmotic pressure. EDA-DA features an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating the conjugation of azide-containing molecules for various biochemical studies and applications in microbiology. -
Peptide
FliC, Serotype a (427-441), S.paratyphi A is a peptide corresponding to amino acids 427 to 441 of the FliC protein from Salmonella paratyphi A. This fragment serves as an important epitope for studying the immune response against this serotype. It is primarily utilized in research focused on bacterial pathogenesis, vaccine development, and immune recognition assays. -
GarKS Peptide
Garvicin KS, GakC is a 32-amino acid peptide that acts as a bacteriocin, specifically targeting the GarKS peptide. This compound exhibits significant antibacterial activity, particularly against Methicillin-Sensitive Staphylococcus aureus (MSSA), with minimal inhibitory concentration (MIC) values revealing a potency hierarchy of GakB > GakC > GakA. Additionally, Garvicin KS, GakC has been shown to inhibit fibroblast viability and proliferation, making it valuable for investigating antibacterial mechanisms and cellular responses in research applications. -
Bioactive Peptide
Drosocin is a bioactive peptide derived from Drosophila melanogaster that functions as a cationic antimicrobial agent. It exhibits significant antibacterial activity, which makes it a valuable tool for studying innate immunity and developing antimicrobial therapies. This synthetic variant retains the original 19-amino acid sequence but lacks the native disaccharide moiety, allowing for comprehensive research on peptide structure-activity relationships and applications in infectious disease models. -
Antimicrobial Peptides
P-113D is an antimicrobial peptide specifically targeting Pseudomonas aeruginosa. It exhibits significant antibacterial activity, making it a valuable tool for research related to cystic fibrosis. The minimum inhibitory concentration (MIC) of P-113D against the ATCC 27853 strain is 3.1 μg/mL. -
Antimicrobial Peptide
Maximin 9 is an antimicrobial peptide derived from the skin secretions of the toad Bombina maxima. This peptide exhibits significant antimicrobial activity, providing a potent defense against a broad spectrum of bacteria and fungi. Maximin 9 is applicable in research focused on antimicrobial mechanism studies and the development of novel therapeutic agents for infectious diseases. -
Antimicrobial Peptide
Maximin 8 is an antimicrobial peptide derived from B. maxima, exhibiting potent antibacterial and antifungal properties. This peptide targets microbial membranes, disrupting integrity and leading to cell death. Due to its broad-spectrum activity, Maximin 8 has applications in the development of novel antimicrobial agents and therapeutic strategies for combating infection. -
Antimicrobial Peptide
Bombolitin II is an antimicrobial peptide derived from bumblebee venom, known for its ability to disrupt cell membranes. It exerts its biological activity by lysing erythrocytes and liposomes, making it a valuable tool in studies of membrane integrity and antimicrobial mechanisms. This peptide is commonly applied in research related to antimicrobial activity and the development of novel therapeutic strategies against infections. -
Lipopeptide
Aspartocin D is a lipopeptide antibiotic known for its antimicrobial activity, particularly against Gram-positive bacteria. This compound serves as an analogue of Amphomycin, providing a valuable tool for investigating bacterial resistance and developing new antimicrobial strategies. Aspartocin D's unique mechanism of action makes it suitable for research applications focused on the study of bacterial infections and the development of novel therapeutics.
