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TAT (47-57) GGG-Cys(Npys)

Catalog No.: A51423
Cell-penetrating Peptide/Delivery Carrier
TAT (47-57) GGG-Cys (Npys) is a cell-penetrating peptide that functions as an effective delivery carrier for therapeutic agents. This peptide facilitates the transport of conjugated drug molecules across biological membranes, enhancing their bioavailability. It is particularly suited for delivering MT1-MMP inhibitors and serves as a valuable tool in research on diseases linked to MT1-MMP activity, including cancer, arthritis, heart disease, and vascular disorders.
TAT (47-57) GGG-Cys(Npys) 1231898-26-2 Cell-penetrating Peptide/Delivery Carrier
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTAT (47-57) GGG-Cys (Npys) is a cell-penetrating peptide that functions as an effective delivery carrier for therapeutic agents. This peptide facilitates the transport of conjugated drug molecules across biological membranes, enhancing their bioavailability. It is particularly suited for delivering MT1-MMP inhibitors and serves as a valuable tool in research on diseases linked to MT1-MMP activity, including cancer, arthritis, heart disease, and vascular disorders.
Product Information
Catalog NumA51423
FormulaC78H135N39O19S2
Molecular Weight1987.29
CAS Number1231898-26-2
SequenceTyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Cys(NPYS)-NH2
Sequence shorteningYGRKKRRQRRRGGG-C(Npys)-NH2
SMILESNCCCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CSSc1ncccc1N(=O)=O)C(N)=O
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