Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Peptide
KT2 is a cationic amphipathic antibacterial peptide that targets bacterial membranes. It exhibits potent antibacterial activity against E. coli O157:H7, demonstrating complete bactericidal effects and significant inhibition of biofilm formation. KT2 interacts with bacterial surface lipopolysaccharides (LPS) and penetrates lipid layers, facilitating its binding to DNA and other cytoplasmic components, making it a valuable reagent for research in antimicrobial therapies and biofilm-related studies. -
Neuropeptide
CART(62-76)(human,rat) targets neuropeptide pathways and functions as a neurotransmitter modulator. This peptide fragment (residues 62-76 of the CART peptide) influences the activity of the striatal noradrenergic system, as well as the corticostriatal and hypothalamic serotoninergic (5-HT) systems in the rat brain. CART(62-76) is valuable for research related to neurobiology, neuropharmacology, and the understanding of neuropeptide signaling in various physiological processes. -
Autoantigen Peptide
Myelin basic protein, MBP (68-86), is a peptide derived from the 68th to 86th amino acid residues of the myelin basic protein sequence. This peptide functions as an autoantigen, initiating immune responses that can lead to the destruction of myelin. MBP (68-86) is utilized in the experimental autoimmune encephalomyelitis (EAE) animal model, making it a valuable tool for investigating the immunological mechanisms involved in multiple sclerosis (MS). -
Bioactive Peptide
PKCε (85-92) is a bioactive peptide that selectively activates epsilon protein kinase C (e-PKC). This peptide effectively induces MARCKS phosphorylation in wild-type cells, demonstrating its role in signaling pathways related to cellular function. However, it does not influence MARCKS phosphorylation in cells derived from knockout mice, indicating its specificity. PKCε (85-92) is valuable for research applications focused on PKC signaling and the study of related cellular processes. -
PKC Substrate
EGFR Peptide is a selective substrate for Protein Kinase C (PKC), facilitating the measurement of PKC activity in various biological contexts. This peptide is instrumental in studies examining PKC's role in cellular signaling pathways, making it a valuable tool for researchers exploring cancer biology, cell proliferation, and differentiation processes. Its specific interaction with PKC allows for accurate assessments of enzyme activity, contributing to a deeper understanding of PKC-mediated signaling mechanisms. -
Peptide
[Glu27]-PKC (19-36) is a peptide that serves as an inactive control for protein kinase C (PKC) (19-36). As a pseudosubstrate peptide inhibitor, it is designed to maintain PKC in an inactive state without the presence of allosteric activators, such as phospholipids. This reagent is applicable in studies examining the regulation of PKC activity and its role in various cellular signaling pathways. Researchers can utilize [Glu27]-PKC (19-36) to assess the impact of active and inactive states of PKC in experimental setups. -
Peptide
Protein Kinase C β Peptide is a peptide fragment derived from Protein Kinase Cβ, which plays a critical role in regulating vascular function. It has been shown that hyperglycemia negatively impacts endothelium-derived nitric oxide production, leading to impaired vasodilation. The inhibition of Protein Kinase Cβ can counteract the reduction in endothelium-dependent vasodilation that occurs during acute hyperglycemia, making this peptide a valuable tool for research into vascular complications associated with diabetes and metabolic disorders. -
Bioactive Peptide
KRPpSQRHGSKY-NH2 is a bioactive peptide that serves as a phosphorylated substrate for protein kinase C (PKC). This compound is utilized in research applications to study signaling pathways and phosphorylation events mediated by PKC. Its role in cellular processes makes it valuable for investigating various biological functions and potential therapeutic targets. -
PKC βII V5 Peptide
Protein Kinase C (660-673) is a peptide derived from the PKC βII isoform, specifically designed to exhibit RACK1-binding affinity. This peptide serves as a valuable tool for studying the interactions of PKC βII with RACK1, providing insights into signaling pathways mediated by Protein Kinase C. Its unique structural properties make it suitable for investigating PKC βII's role in cellular processes, including proliferation and differentiation. -
PKC Pseudosubstrate Inhibitor
Protein Kinase C (19-35) Peptide serves as a pseudosubstrate inhibitor of Protein Kinase C (PKC). By potentially blocking the substrate-binding site within the kinase domain, this peptide renders the cytoplasmic form of PKC inactive. This inhibition is valuable for investigating PKC-related signaling pathways and understanding its role in various cellular processes. Its applications extend to research focused on cell proliferation, differentiation, and apoptosis associated with PKC activity. -
PKCδ Substrate
PKCδ Peptide Substrate is a highly specific substrate that targets the δ isoform of Protein Kinase C (PKCδ). Featuring the amino acid sequence corresponding to residues 422-443 of murine eEF-1α and incorporating Thr-431, this peptide supports detailed studies of PKCδ activity. It is suitable for a variety of research applications, including kinase assays and understanding PKCδ's role in cellular signaling pathways. -
Inhibitor Peptide
pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively targets and disrupts the interactions of Protein Interacting with C kinase 1 (PICK1). This compound is known to exert opposing effects on synaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) function relative to PICK1 expression. It serves as a valuable tool for studying synaptic signaling pathways and understanding the role of PICK1 in synaptic plasticity and related neurobiological processes. -
MBP Peptide
Ac-MBP (4-14) Peptide is an acetylated derivative of the myelin basic protein (MBP) sequence encompassing amino acids 4 to 14. This peptide serves as a selective substrate for protein kinase C (PKC), facilitating accurate biochemical assays. Ac-MBP (4-14) Peptide is suitable for PKC activity assays in crude extracts, allowing for the assessment of PKC function without the need for prior purification steps to remove interfering kinases or phosphatases. -
PKC Inhibitor
[Ala107]MBP(104-118) is a noncompetitive inhibitor of protein kinase C (PKC), exhibiting IC50 values between 46-145 μM. This peptide is utilized in research to study PKC activity and its role in cellular signaling pathways. Its ability to selectively inhibit PKC makes it a valuable tool in investigating the implications of PKC in various disease states and pharmacological interventions. -
Neuropeptide
Neuropeptide DF2 is a neuropeptide derived from crayfish, specifically a member of the DRNFLRFamide family. It enhances neurotransmitter release and increases the amplitude of excitatory post-synaptic potentials (EPSP) via activation of calcium/calmodulin-dependent protein kinase pathways. This compound is valuable for research in neurobiology and synaptic transmission. -
Peptide
Protein Kinase C γ Peptide is a bioactive peptide fragment derived from Protein Kinase Cγ, which plays a crucial role in cellular signaling pathways. This peptide is involved in the regulation of nuclear import mechanisms associated with recessive ataxia-related aprataxin and has implications in the study of dominant ataxia disorders. It is a valuable tool for researchers exploring the molecular mechanisms underlying ataxia and related neurodegenerative conditions. -
Peptide
Pep2m, myristoylated is a cell-permeable peptide that targets protein kinase ζ (PKMζ). This compound is known to disrupt the interactions between N-ethylmaleimide-sensitive factor (NSF) and glutamate receptor subunit 2 (GluR2), providing valuable insights into the roles of PKMζ in cellular signaling. Pep2m, myristoylated is useful for researching synaptic transmission and plasticity, as well as studying the molecular mechanisms underlying memory and learning processes. -
PKC Inhibitor
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a selective inhibitor of protein kinase C (PKC), exhibiting an IC50 of 75 μM. This compound effectively inhibits the induction of the IL-2 receptor and production of IL-2 in the Jurkat human leukemic cell line. It can be utilized in research focused on understanding PKC-related signaling pathways and their role in immune responses. -
Protein Kinase C Peptide
Protein Kinase C α Peptide (TFA) is a synthetic peptide derived from Protein Kinase C alpha, which functions as a lipid-dependent serine/threonine protein kinase. This reagent plays a critical role in modulating various cellular processes such as cell survival, proliferation, differentiation, migration, and adhesion. It is widely utilized in research applications exploring signaling pathways and cellular responses pertinent to cancer and other diseases. -
PKC Activator
Protein Kinase C (530-558) is a potent activator of Protein Kinase C (PKC). This peptide fragment has been shown to significantly inhibit osteoclastic bone resorption, making it valuable for research on bone metabolism and related disorders. Its specific activation of PKC can provide insights into the signaling pathways involved in various cellular processes, contributing to studies in cell biology and pharmacology. -
Peptide
FKKSFKL-NH2 is a selective peptide targeting protein kinase C (PKC). This compound is valuable for studying PKC-mediated signaling pathways and its involvement in various biochemical processes. Researchers can utilize FKKSFKL-NH2 to explore its potential roles in cell signaling, proliferation, and differentiation, contributing to a deeper understanding of PKC-related functions in cellular biology. -
PKC Substrate
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) serves as a selective substrate for phosphorylation by protein kinase C (PKC). This reagent is useful for assessing PKC activity in various biological contexts, providing insights into signaling pathways involving PKC and glycogen metabolism. Researchers can utilize this substrate to elucidate the regulatory mechanisms of PKC in cellular processes. -
Signal Accepts Peptide
Protein Kinase C Peptide Substrate is specifically designed to act as a substrate for Protein Kinase C, a crucial player in cellular signal transduction. This substrate participates in the phosphorylation of serine and threonine residues in target proteins, modulating various cellular processes in response to second messengers. Its key biological activities include regulation of nervous, endocrine, exocrine, inflammatory, and immune responses. This reagent is valuable for research applications aimed at understanding signaling pathways and the functional roles of Protein Kinase C in cellular physiology. -
BMP Encephalitogenic Epitope
Ac-MBP (1-11) is a synthetic peptide that represents the primary encephalitogenic epitope derived from myelin basic protein (MBP). This peptide is critical for studies on multiple sclerosis and other autoimmune disorders, as it plays a significant role in immune response and T cell activation. Ac-MBP (1-11) is widely utilized in research to understand the mechanisms of demyelination and to explore potential therapeutic interventions. -
Bioactive Peptide
PKCd (8-17) is a bioactive peptide derived from the V1 domain of protein kinase C (PKC)d. This peptide effectively inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Its inhibitory effects on PKCd contribute to reduced ischemic damage in cardiac and cerebral cells, promote fibroblast proliferation, and inhibit graft coronary artery disease in murine models, making it valuable for research in cardiac and cerebrovascular conditions. -
PKA Substrate
Phosphate acceptor peptide is a specific substrate for cyclic AMP-dependent protein kinase (PKA), facilitating the study of phosphorylation processes. Additionally, it exhibits weak inhibitory activity against protein kinase C (PKC), making it useful in exploring the mechanisms of kinase signaling pathways. This reagent is applicable in various biochemical assays aimed at understanding cellular signaling and regulation. -
PKCβII Inhibitor
PKCβII Peptide Inhibitor I is a selective inhibitor of Protein Kinase C beta II (PKCβII). This peptide demonstrates significant cardioprotective effects in rat models of ischemia/reperfusion injury, making it a valuable tool in cardiovascular research. Additionally, it has been shown to prevent vascular endothelial dysfunction, highlighting its potential applications in studying vascular health and related pathologies. -
TfR Binding Peptide
TfR-T12 is a transferrin receptor (TfR) binding peptide that effectively penetrates the blood-brain barrier. With a binding affinity in the nanomolar range, it serves as a valuable tool for targeted delivery of therapeutic agents across the central nervous system. This peptide is particularly applicable in research focused on neurological disorders and drug delivery systems involving TfR interactions. -
TfR Binding Peptide
Cys-LT7 is a Cysteine-modified analog of the LT7 peptide, which targets the transferrin receptor (TfR) through a binding site that is distinct from that of transferrin. This peptide demonstrates high affinity for TfR, making it a valuable tool for constructing targeted drug delivery systems aimed at enhancing cellular uptake of therapeutics. Cys-LT7 is applicable in various research studies focusing on peptide-mediated targeting and drug formulation strategies. -
Folate Receptor Alpha Peptide Ligand
FRα-targeting peptide C7 is a selective ligand that specifically binds to the folate receptor alpha (FRα). This peptide demonstrates targeted binding to FRα-expressing cells, facilitating in vivo tumor localization. It is a valuable tool for research applications in tumor diagnosis and therapeutic development, enabling targeted delivery of diagnostic and therapeutic agents. -
Chromogenic Peptide Substrate
Pyr-Pro-Arg-pNA hydrochloride is a chromogenic peptide substrate primarily targeting Factor XI and Activated Protein C (APC). It serves as a noncompetitive inhibitor of factor XI activation by binding to the active site of the factor XIa-light chain. This compound is essential for quantifying APC amidolytic activity in various biological assays, making it a valuable tool in coagulation research. -
Chromogenic Peptide Substrate
Pyr-Pro-Arg-pNA is a chromogenic peptide substrate specifically designed for Factor XI and Activated Protein C (APC). This reagent enables noncompetitive inhibition of Factor XI activation by binding to the active site of the factor XIa light chain. Pyr-Pro-Arg-pNA is primarily utilized for assessing APC amidolytic activity, making it a valuable tool in coagulation research and related studies. -
ATR Substrate
ATR kinase substrate peptide (ASELPASQPQPFSAKKK) functions as a specific substrate for ATR protein kinase, facilitating the detection of ATR kinase activity in biological research. This peptide is instrumental in studying cellular responses to DNA damage and the associated signaling pathways. It plays a critical role in validating ATR kinase activity and exploring its implications in cancer biology and therapeutic development. -
Cdk5 Peptide Inhibior
Cdk5i peptide is an inhibitor targeting cyclin-dependent kinase 5 (CDK5), displaying a strong binding affinity for the CDK5/p25 complex with a dissociation constant (Kd) of 0.17 μM. This peptide effectively disrupts the interaction between CDK5 and p25, subsequently reducing the kinase activity of the CDK5/p25 complex. Cdk5i peptide is particularly relevant for research into neurodegenerative diseases, providing a valuable tool for elucidating the role of CDK5 in neuronal function and pathology. -
Phosphopeptide
Histone H1-derived Peptide is a phosphopeptide designed to serve as a substrate for cyclin-dependent kinases (CDKs), specifically aligning with the optimal recognition motif for CDK1-cyclin B1. Its primary application lies in the detection of CDK1-cyclin B1 enzyme activity, making it an essential tool for studies focused on cell cycle regulation and protein phosphorylation dynamics. This peptide can facilitate research into the mechanisms governing cellular proliferation and the roles of CDKs in various biological processes. -
CDK2 Inhibitor
Cdk2/Cyclin Inhibitory Peptide I (Tat-LFG) is a specific inhibitor of cyclin-dependent kinase 2 (CDK2). It has demonstrated the ability to induce apoptosis in U2OS osteosarcoma cells in a dose-dependent manner, making it a valuable tool for studying CDK2-mediated cell cycle regulation. This peptide is suitable for research applications aimed at understanding the role of CDK2 in cancer biology and potential therapeutic interventions. -
Bioactive Peptide
Cdc2 kinase substrate is a bioactive peptide that serves as a specific substrate for cyclin-dependent protein kinase 1 (CDC2; CDK1). This substrate plays a crucial role in the regulation of the cell cycle by facilitating the phosphorylation activity associated with CDC2, enabling the transition from G2 to M phase. It is particularly useful in studies focused on cell cycle regulation, protein kinase signaling pathways, and the development of CDK inhibitors. -
CDK2 Inhibitor
Cdk2/Cyclin Inhibitory Peptide II is a specific inhibitor of cyclin-dependent kinase 2 (CDK2), primarily influencing cell cycle regulation. This peptide has demonstrated the ability to induce apoptosis in U2OS osteosarcoma cells in a dose-dependent manner. Its application in research includes investigations into cell cycle dynamics and therapeutic strategies for cancer treatment. -
Bioactive Peptide
SAP6 is a bioactive peptide that inhibits viral entry into host cells. This compound exhibits significant antiviral activity, making it a valuable tool for research in virology and infectious diseases. SAP6 can be utilized in studies aimed at understanding viral mechanisms and developing potential therapeutic strategies against viral infections. -
Immunodominant Peptides
NQK-Q8 peptide is an immunodominant peptide derived from the SARS-CoV-2 virus, specifically targeting T cell responses. It plays a crucial role in the evaluation of immune responses in COVID-19 research, making it a valuable tool for vaccine development and immunological studies. This peptide can assist in the identification and characterization of SARS-CoV-2-specific T cell responses in various experimental settings. -
Bioactive Peptide
HR2-18 is a bioactive peptide that targets the interaction between the SARS-CoV virus and host cell membranes. It demonstrates potent inhibition of viral penetration, thereby providing a valuable tool for studying viral entry mechanisms and developing antiviral strategies. This peptide is particularly relevant for research focused on coronavirus infections and therapeutic interventions. -
Arginine-enriched Peptide
BMV Gag-(7−25) is an arginine-enriched peptide known for its cell-penetrating capabilities. This peptide facilitates the delivery of therapeutic agents and genetic material, making it a valuable tool in drug delivery and gene therapy research. Its cellular uptake properties enhance the efficacy of treatments involving nucleic acids and other biomolecules. -
Peptide
Glu-Ala-Leu-Phe-Gln-pNA is a peptide substrate specific for Chiba virus 3C-like protease (CVP). This compound can be utilized to study proteolytic activity and enzyme kinetics related to CVP, providing insights into viral replication and pathogenesis. Its application in biochemical assays enables researchers to investigate therapeutic targets and potential inhibitors of the Chiba virus. -
Peptide-Paclitaxel Conjugate
ANG1005 is a peptide-paclitaxel conjugate designed to enhance brain delivery through targeted transport mechanisms. By covalently linking three paclitaxel molecules to Angiopep-2, ANG1005 effectively utilizes the low-density lipoprotein receptor-related protein (LRP1) pathway to cross the blood-brain and blood-cerebrospinal barriers. This innovative compound exhibits potent cytotoxicity against malignant cells, making it a valuable tool for research in brain tumor therapeutics and assessing drug delivery systems in neuro-oncology. -
Dipeptide
L-gamma-Glutamyl-L-threonine, a dipeptide, is formed through the condensation of the carboxyl group of L-glutamic acid and the amino group of L-threonine. This compound demonstrates antibacterial activity against Gram-negative bacteria and is linked to immune regulation. Additionally, L-gamma-Glutamyl-L-threonine serves as a flavor compound and can be utilized in research focused on inflammation and bacterial infections. -
Peptide-Drug Conjugate
PhAc-ALGP-Dox is a peptide-drug conjugate designed for targeted anticancer therapy. This prodrug demonstrates significant cytotoxic activity against triple-negative breast cancer (TNBC) cell lines, with IC50 values ranging from 311 nM to 34.25 μM for E0771, MDA-MB-231, and MDA-MB-468, as well as exhibiting effects on colorectal carcinoma (CrC) cells (LS 174T) and normal epithelial cells. Its unique mechanism allows for selective delivery of doxorubicin, making it a valuable tool for research applications focused on improving chemotherapy efficacy and reducing off-target effects in cancer treatment. -
Peptide
BPP 5a is a bradykinin-potentiating peptide known for its vasorelaxant properties, derived from Bothrops jararaca venom. This peptide functions as an angiotensin-converting enzyme (ACE) inhibitor with a Ki value of 400 nM. BPP 5a is primarily utilized in research focused on hypertension and cardiovascular diseases, offering insights into potential therapeutic applications. -
Bioinspired Peptide
DDDEEKC is a bioinspired peptide that selectively adsorbs onto enamel surfaces, mimicking the function of statherin, a salivary protein. This peptide acts as a guiding agent for the remineralization of tooth enamel, significantly enhancing the regeneration of hydroxyapatite (HAP). DDDEEKC is valuable for research focused on in-situ repair of enamel demineralization, including conditions such as dental caries. -
Antitumor Peptide
Tezuvotide tetraxetan is an antitumor peptide designed to target cancer cells through specific receptor interactions. It exhibits potent antineoplastic activity, making it a valuable tool for studying tumor biology and therapeutic approaches in cancer research. Its mechanism of action and specificity provide insights into potential applications in targeted therapies and clinical investigations. -
Polypeptide
Ganipatide is a glucose-dependent insulinotropic polypeptide consisting of 31 amino acids. It plays a pivotal role in enhancing insulin secretion in response to food intake, making it significant in the study of glucose metabolism and diabetes management. This polypeptide is useful for investigating mechanisms of insulin regulation and potential therapeutic approaches for type 2 diabetes.
