Catalog No.
Product Name
Application
Product Information
Citations
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ACE2PD α1 Helix Peptide
SBP1 peptide is a 23-amino acid synthetic fragment derived from the α1 helix of the ACE2 PD region. This peptide demonstrates micromolar affinity for the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein, facilitating insights into viral entry mechanisms. It is useful in research applications focused on viral pathogenesis and the development of therapeutic strategies targeting ACE2 interactions. -
Antihypertensive Peptide
YKYY is an antihypertensive peptide that functions as an Angiotensin I-converting enzyme (ACE) inhibitor, with an IC50 of 64.2 μM. Isolated from the peptic digest of wakame (Undaria pinnatifida), YKYY exhibits potential for modulating blood pressure. This compound is valuable for research investigating mechanisms of hypertension and the development of novel antihypertensive therapies. -
Antihypertensive Peptide
Tyrosylhistidine is a dipeptide comprised of tyrosine and histidine, exhibiting antihypertensive properties. It has demonstrated the ability to significantly reduce blood pressure in murine models of spontaneous hypertension. This compound serves as a valuable tool for research in cardiovascular physiology and antihypertensive drug development. -
ACE Substrate Peptide
AC-SDKP-NH2 is a substrate peptide of Angiotensin-converting enzyme (ACE). It exhibits significant anti-inflammatory and anti-fibrotic activities by directly targeting tissues, thereby preventing or reversing excessive fibrosis without impacting blood pressure or left ventricular hypertrophy (LVH). AC-SDKP-NH2 effectively attenuates inflammation, as well as cell differentiation, proliferation, and migration, resulting in reduced fibrosis in cardiac, vascular, and renal tissues in mouse models. This reagent is applicable in cardiovascular research, particularly in studies related to hypertension and fibrosis-associated conditions. -
Peptide Fragment
[Tyr6]-Angiotensin II is a peptide fragment that functions as a selective antagonist of the angiotensin II receptor. This compound exhibits biological activity by modulating cardiovascular responses and renal function, making it valuable for research on hypertension and related disorders. Its ability to influence the renin-angiotensin system positions it as a useful tool in studies aimed at understanding the physiological and pathophysiological roles of angiotensin peptides. -
Tripeptide
IRW is an orally active tripeptide derived from egg white, known for its angiotensin-converting enzyme (ACE) inhibitory properties. This compound exhibits significant potential in preventing high-fat diet-induced non-alcoholic fatty liver disease (NAFLD) by modulating hepatic lipid metabolism and enhancing mitochondrial content. IRW has been shown to reduce hepatic triglyceride levels and lipid droplet size, while also increasing the activity of mitochondrial complexes and citrate synthase. Its ability to activate key pathways, including phosphorylation of 5’-AMP-activated protein kinase and increasing microsomal triglyceride transfer protein abundance, makes IRW a valuable reagent for studies in inflammation and metabolic disorders. -
Neuropeptide Y Y1 Receptor Antagonist
Neuropeptide Y Y1 Receptor Antagonist 1 is a potent antagonist of the neuropeptide Y Y1 receptor (Y1R), exhibiting a Ki value of 0.19 nM. This compound serves as a valuable tool in neurobiology research, facilitating the investigation of neuropeptide signaling pathways and their roles in various physiological processes. Its applications include studying the effects of Y1R modulation on neuroendocrine responses, food intake, and anxiety-related behaviors. -
β-catenin/GSK-3β Activator
C-Peptide 1 (rat) is a peptide that functions as an activator of β-catenin and GSK-3β. Its primary mechanism involves the regulation of the Wnt/β-catenin signaling pathway, which plays a crucial role in cellular processes such as proliferation and differentiation. C-Peptide 1 (rat) is utilized in cancer research, contributing to studies aimed at understanding tumorigenesis and potential therapeutic interventions. -
GSK-3 Substrate
Phospho-Glycogen Synthase Peptide-2 is a specific substrate for glycogen synthase kinase-3 (GSK-3). This peptide facilitates the study of GSK-3 activity and its role in various signaling pathways. It is also suitable for affinity purification of protein-serine kinases, enabling researchers to investigate kinase interactions and functions in cellular processes. -
Chromogenic Peptide Substrate
Pyr-Pro-Arg-pNA hydrochloride is a chromogenic peptide substrate primarily targeting Factor XI and Activated Protein C (APC). It serves as a noncompetitive inhibitor of factor XI activation by binding to the active site of the factor XIa-light chain. This compound is essential for quantifying APC amidolytic activity in various biological assays, making it a valuable tool in coagulation research. -
Chromogenic Peptide Substrate
Pyr-Pro-Arg-pNA is a chromogenic peptide substrate specifically designed for Factor XI and Activated Protein C (APC). This reagent enables noncompetitive inhibition of Factor XI activation by binding to the active site of the factor XIa light chain. Pyr-Pro-Arg-pNA is primarily utilized for assessing APC amidolytic activity, making it a valuable tool in coagulation research and related studies. -
ATR Substrate
ATR kinase substrate peptide (ASELPASQPQPFSAKKK) functions as a specific substrate for ATR protein kinase, facilitating the detection of ATR kinase activity in biological research. This peptide is instrumental in studying cellular responses to DNA damage and the associated signaling pathways. It plays a critical role in validating ATR kinase activity and exploring its implications in cancer biology and therapeutic development. -
Cdk5 Peptide Inhibior
Cdk5i peptide is an inhibitor targeting cyclin-dependent kinase 5 (CDK5), displaying a strong binding affinity for the CDK5/p25 complex with a dissociation constant (Kd) of 0.17 μM. This peptide effectively disrupts the interaction between CDK5 and p25, subsequently reducing the kinase activity of the CDK5/p25 complex. Cdk5i peptide is particularly relevant for research into neurodegenerative diseases, providing a valuable tool for elucidating the role of CDK5 in neuronal function and pathology. -
Phosphopeptide
Histone H1-derived Peptide is a phosphopeptide designed to serve as a substrate for cyclin-dependent kinases (CDKs), specifically aligning with the optimal recognition motif for CDK1-cyclin B1. Its primary application lies in the detection of CDK1-cyclin B1 enzyme activity, making it an essential tool for studies focused on cell cycle regulation and protein phosphorylation dynamics. This peptide can facilitate research into the mechanisms governing cellular proliferation and the roles of CDKs in various biological processes. -
CDK2 Inhibitor
Cdk2/Cyclin Inhibitory Peptide I (Tat-LFG) is a specific inhibitor of cyclin-dependent kinase 2 (CDK2). It has demonstrated the ability to induce apoptosis in U2OS osteosarcoma cells in a dose-dependent manner, making it a valuable tool for studying CDK2-mediated cell cycle regulation. This peptide is suitable for research applications aimed at understanding the role of CDK2 in cancer biology and potential therapeutic interventions. -
Bioactive Peptide
Cdc2 kinase substrate is a bioactive peptide that serves as a specific substrate for cyclin-dependent protein kinase 1 (CDC2; CDK1). This substrate plays a crucial role in the regulation of the cell cycle by facilitating the phosphorylation activity associated with CDC2, enabling the transition from G2 to M phase. It is particularly useful in studies focused on cell cycle regulation, protein kinase signaling pathways, and the development of CDK inhibitors. -
CDK2 Inhibitor
Cdk2/Cyclin Inhibitory Peptide II is a specific inhibitor of cyclin-dependent kinase 2 (CDK2), primarily influencing cell cycle regulation. This peptide has demonstrated the ability to induce apoptosis in U2OS osteosarcoma cells in a dose-dependent manner. Its application in research includes investigations into cell cycle dynamics and therapeutic strategies for cancer treatment. -
Bioactive Peptide
SAP6 is a bioactive peptide that inhibits viral entry into host cells. This compound exhibits significant antiviral activity, making it a valuable tool for research in virology and infectious diseases. SAP6 can be utilized in studies aimed at understanding viral mechanisms and developing potential therapeutic strategies against viral infections. -
Immunodominant Peptides
NQK-Q8 peptide is an immunodominant peptide derived from the SARS-CoV-2 virus, specifically targeting T cell responses. It plays a crucial role in the evaluation of immune responses in COVID-19 research, making it a valuable tool for vaccine development and immunological studies. This peptide can assist in the identification and characterization of SARS-CoV-2-specific T cell responses in various experimental settings. -
Bioactive Peptide
HR2-18 is a bioactive peptide that targets the interaction between the SARS-CoV virus and host cell membranes. It demonstrates potent inhibition of viral penetration, thereby providing a valuable tool for studying viral entry mechanisms and developing antiviral strategies. This peptide is particularly relevant for research focused on coronavirus infections and therapeutic interventions. -
Arginine-enriched Peptide
BMV Gag-(7−25) is an arginine-enriched peptide known for its cell-penetrating capabilities. This peptide facilitates the delivery of therapeutic agents and genetic material, making it a valuable tool in drug delivery and gene therapy research. Its cellular uptake properties enhance the efficacy of treatments involving nucleic acids and other biomolecules. -
Peptide
Glu-Ala-Leu-Phe-Gln-pNA is a peptide substrate specific for Chiba virus 3C-like protease (CVP). This compound can be utilized to study proteolytic activity and enzyme kinetics related to CVP, providing insights into viral replication and pathogenesis. Its application in biochemical assays enables researchers to investigate therapeutic targets and potential inhibitors of the Chiba virus. -
Peptide-Paclitaxel Conjugate
ANG1005 is a peptide-paclitaxel conjugate designed to enhance brain delivery through targeted transport mechanisms. By covalently linking three paclitaxel molecules to Angiopep-2, ANG1005 effectively utilizes the low-density lipoprotein receptor-related protein (LRP1) pathway to cross the blood-brain and blood-cerebrospinal barriers. This innovative compound exhibits potent cytotoxicity against malignant cells, making it a valuable tool for research in brain tumor therapeutics and assessing drug delivery systems in neuro-oncology. -
Dipeptide
L-gamma-Glutamyl-L-threonine, a dipeptide, is formed through the condensation of the carboxyl group of L-glutamic acid and the amino group of L-threonine. This compound demonstrates antibacterial activity against Gram-negative bacteria and is linked to immune regulation. Additionally, L-gamma-Glutamyl-L-threonine serves as a flavor compound and can be utilized in research focused on inflammation and bacterial infections. -
Antibiotic/Antimicrobial Peptide
Aurein 5.2 is an antimicrobial peptide with potent antibiotic properties. It exhibits broad-spectrum activity against various bacterial strains, making it a valuable tool in studies related to infection control and antibiotic resistance. Its mechanism of action involves disrupting bacterial cell membranes, leading to cell lysis. Aurein 5.2 is applicable in research focused on antimicrobial development and the understanding of peptide-based therapeutics. -
Bioactive Peptide
NRC-16 is a bioactive peptide that functions as a pleurocidin-like cationic antimicrobial peptide (AMP). It exhibits potent antimicrobial activity against a range of pathogens, making it a valuable tool for research in infectious diseases and host defense mechanisms. Its unique properties facilitate studies in peptide structural biology and the development of novel antimicrobial therapies. -
antimicrobial peptides
LZ1 peptide is an antimicrobial peptide that exhibits antimalarial activity. It demonstrates the ability to inhibit the growth of Plasmodium species, making it a valuable candidate for research in malaria treatment and prevention strategies. This peptide can be utilized in studies focusing on the development of novel antimicrobial agents and the mechanisms of host-pathogen interactions. -
Tool Peptide
SP2 is a 14-amino acid synthetic tool peptide that functions by inducing growth arrest in MTLa cells of Candida albicans through modulation of cell cycle regulation. This peptide is valuable for research applications focusing on fungal biology, specifically in understanding the mating type locus and associated regulatory mechanisms. Its unique properties make it an essential reagent for studies investigating cell growth and development in yeast models. -
Antibiotic/Antimicrobial Peptide
Aurein 2.3 is an antibiotic antimicrobial peptide targeting bacterial ATPases, primarily inhibiting E. coli ATPase activity. This compound demonstrates significant antibacterial activity, effectively suppressing cell growth in susceptible bacterial strains. Aurein 2.3 serves as a valuable tool in microbiological studies and the development of new antimicrobial therapies. -
Antibiotic Peptide
Aurein 1.1 is an antibiotic peptide derived from the skin of the Australian Bell Frog (Litoria raniformis). It demonstrates potent antimicrobial activity against a variety of Gram-positive and Gram-negative bacteria. This peptide is valuable for research applications in the field of antimicrobial resistance and the development of new therapeutic agents targeting bacterial infections. -
Antibiotic Peptide
Aurein 2.1 is an antibiotic peptide derived from the skin secretions of Australian Bell Frogs, specifically Litoria aurea and Litoria raniformis. It exhibits significant antimicrobial activity against a range of bacterial strains, making it a valuable tool for research in antibiotic development and investigations into novel antimicrobial mechanisms. This peptide is of particular interest for studies related to infection control and the exploration of natural antimicrobial agents. -
Cationic antimicrobial peptide
Omiganan is a cationic antimicrobial peptide that exhibits potent activity against both gram-positive and gram-negative bacteria, as well as Candida species. As an analogue of indolicidin, Omiganan is valuable for studying its effects on microbial infections. Its applications extend to research on conditions such as acne and addressing issues related to alcohol-induced nasal problems. -
Skin-Antimicrobial Peptide
Human β-defensin-1 (HβD-1) is a cationic skin-antimicrobial peptide that targets a broad spectrum of bacteria. It is produced by various epithelial surfaces as well as circulatory and reproductive tract cells. This peptide exhibits significant antimicrobial activity, making it a valuable reagent for research applications focused on innate immunity and skin defense mechanisms. -
Polypeptide Antibiotic
Colistin is a polypeptide antibiotic primarily targeting Gram-negative bacteria. It demonstrates potent activity against multidrug-resistant strains such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. Due to its nephrotoxic potential, careful consideration is required during research. Colistin is valuable for studying infections caused by Gram-negative bacilli and exploring antibiotic resistance mechanisms. -
Lipoglycopeptide Antibiotic
Dalbavancin is a semisynthetic lipoglycopeptide antibiotic targeting Gram-positive bacteria. It exhibits potent bactericidal activity, with minimal inhibitory concentrations (MIC90) of 0.06 μg/mL against Staphylococcus aureus and 0.25 μg/mL against Bacillus anthracis. This compound is primarily utilized in research applications focused on bacterial infections and the development of novel antimicrobial therapies. -
Polypeptide Antibiotics
Polymyxin B2 is a polypeptide antibiotic that primarily targets the cell membrane of gram-negative bacteria. It exerts its antibacterial effect by binding to lipopolysaccharide components, leading to membrane disruption and subsequent cell lysis. This compound is relevant for antibiotic research and development, particularly in addressing drug-resistant bacterial strains. -
Antibiotic Peptide
Aurein 1.2 is an antibiotic peptide derived from amphibian sources, exhibiting potent antimicrobial and anticancer properties. This peptide targets bacterial membranes, leading to disruption and cell death, making it valuable in the study of antibiotic resistance and cancer therapeutics. Aurein 1.2 is ideal for research applications focused on the development of novel antimicrobial agents and exploring mechanisms of cancer cell apoptosis. -
Glycopeptide Antibiotic
A40926 is a glycopeptide antibiotic that targets the bacterial cell wall peptidoglycan precursor D-alanyl-D-alanine (D-Ala-D-Ala). It functions by irreversibly inhibiting cell wall synthesis through competitive binding, demonstrating significant bactericidal activity against Gram-positive bacteria, including Staphylococcus and Streptococcus, as well as Neisseria gonorrhoeae, with MIC values ranging from 0.06 to 2 μg/mL. Additionally, A40926 is effective against penicillin-resistant strains, disrupting peptidoglycan cross-linking and leading to bacterial lysis and death. The compound's fat-soluble fatty acid structure enhances serum concentrations and extends its duration of action, with a terminal half-life of 61.22 hours in rats. -
Antibiotic Peptide
Dermcidin-1L (human) is an antibiotic peptide that targets microbial pathogens with its inherent antimicrobial activity. Secreted by sweat glands, it plays a crucial role in skin defense mechanisms. Research applications include studies of inflammatory skin disorders and the investigation of innate immune responses. -
Lipopeptide Antibiotic
Globomycin is a lipopeptide antibiotic that acts as an irreversible inhibitor of signal peptidase II (LspA). By binding to the peptidase, Globomycin disrupts the processing of prolipoproteins, demonstrating significant antibacterial activity against the mollicute Spiroplasma melliferum with a minimum inhibitory concentration (MIC) of 6.25-12.5 μM. This compound is valuable for research applications focused on bacterial protein processing and antibiotic resistance mechanisms. -
Glycopeptide Antibiotic
Chloroorienticin A is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by targeting the transglycosylation activity in gram-positive bacteria. This compound demonstrates potent antibacterial activity against staphylococci and streptococci, making it a valuable tool for research on antibiotic resistance and bacterial pathogenesis. Its efficacy in inhibiting the growth of these pathogens supports its use in studying the mechanisms of antibiotic action and resistance development in clinical strains. -
Glycopeptide Antibiotic
Phleomycin D1 is a glycopeptide antibiotic that targets DNA. It exerts its biological activity by binding to and cleaving DNA, leading to cell death. Additionally, Phleomycin D1 induces cell cycle arrest at the S phase, making it a valuable reagent for research applications in cancer biology and molecular genetics. -
Antifungal Peptide
Pezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections. -
Antibacterial Peptide
D2A21 is an antibacterial peptide derived from cecropins that exhibits potent antimicrobial activity. It has a minimum cidal concentration of 21.69 μg/mL against Chlamydia trachomatis, demonstrating its effectiveness in combating bacterial infections. This peptide is valuable for research applications aimed at developing novel antimicrobial therapies and studying bacterial resistance mechanisms. -
HPV Epitope Peptides Fragment
Human Papillomavirus (HPV) E7 protein (49-57) is a fragment of the E7 protein, specifically the epitope spanning amino acid residues 49 to 57, which is restricted by the H-2d MHC class I molecule. This peptide is vital for studying HPV-induced tumorigenesis and immune response mechanisms. It is commonly utilized in research applications focusing on HPV vaccination, T cell recognition, and the understanding of viral oncogenesis. -
Polypeptide
HHV-2 Envelope Glycoprotein G (552-574) is a polypeptide derived from the glycoprotein G (gG-2) of herpes simplex virus type 2 (HSV-2). This immunodominant region elicits a robust immune response, making it a valuable target for serological studies and vaccine development related to HSV-2. It is critical for understanding the pathogenesis of herpes simplex virus infections and can be used in diagnostic assays to detect HSV-2 specific antibodies. -
FITC Labeled Peptide
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578) is a fluorescently labeled peptide that targets the immunodominant region of herpes simplex virus type 2 (HSV-2) glycoprotein G (gG-2). This reagent exhibits strong reactivity with HSV-2 sera, making it suitable for various research applications in virology, including antibody detection and vaccine development studies. Its fluorescent labeling facilitates visualization and analysis in cellular assays. -
Virus Replication Inhibitor
Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH) is a potent inhibitor of viral replication, targeting and disrupting the membrane fusion activity of viral glycoproteins. This compound is essential for studying viral pathogenesis and developing antiviral therapies, as it effectively impedes the entry of viruses into host cells. Its applications extend to research focused on the mechanisms of viral infections and the exploration of therapeutic strategies to prevent viral replication. -
Peptide
Bursin is a peptide targeting B precursor cells, promoting their phenotypic differentiation in both mammalian and avian systems. This compound is known to enhance cyclic guanosine monophosphate (cGMP) levels in human B-cell lines, such as Daudi. Additionally, Bursin exhibits immunomodulatory properties, which bolster the immune response against infections, including those caused by H9N2. Its applications in immunology and cellular biology research make it a valuable tool for investigating immune mechanisms and enhancing vaccine efficacy. -
Peptide Fragment
NS2 (114-121), Influenza is a peptide fragment derived from the nonstructural protein 2 (NS2) of the influenza virus. This influenza epitope is primarily utilized in research focused on CD8+ cytotoxic T lymphocyte (CTL) responses during antiviral immune reactions. NS2 (114-121) serves as an important tool for studying the mechanisms of T cell-mediated immunity against influenza infections.
