Catalog No.
Product Name
Application
Product Information
Citations
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Antiviral Peptide
Antiviral agent 76 is an antiviral peptide featuring azide functional groups, specifically designed to inhibit the hepatitis C virus (HCV). This compound demonstrates significant antiviral activity, making it a valuable tool for researching HCV interactions and potential therapeutic strategies. Its unique structure allows for investigations into peptide-based antiviral mechanisms and applications in virology. -
Peptide Substrate
Hepatitis C Virus S5A/5B is a synthetic peptide substrate designed to mimic the NS5A/5B junction of the nonstructural protein (NS) in the Hepatitis C virus. This peptide serves as an effective substrate for studying the activity of HCV NS3 protease, facilitating research on viral replication and proteolytic processing. It is valuable for investigations into antiviral drug development and the molecular mechanisms of HCV pathology. -
HIV-1 TAT Peptide
TAT (YGRKKRRQRRR) is a cell-penetrating peptide derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1). It enhances the solubility and yield of heterologous proteins, making it a valuable tool in research applications related to protein expression and purification. TAT's ability to facilitate cellular uptake has made it a useful reagent in studies exploring intracellular delivery mechanisms and molecular therapeutics. -
HIV-1 Polypeptide
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from residues 48-60 of the HIV-1 Tat protein, functioning as a facilitator for cellular uptake. This peptide enables the effective delivery of exogenous macromolecules into cells without causing disruption to cellular integrity. Its unique mechanism enhances research applications in drug delivery, gene therapy, and the study of intracellular processes associated with HIV-1. -
CD4 Receptor Ligand
Peptide T is an octapeptide derived from the V2 region of the HIV-1 gp120 protein. It functions as a ligand for the CD4 receptor, effectively blocking the interaction between HIV and CD4, thereby inhibiting viral entry into host cells. This compound is essential for research in HIV pathogenesis and therapeutic development targeting CD4 receptor interactions. -
HIV-1 Polypeptide
TAT (48-57) is a cell-permeable peptide derived from the HIV-1 transactivator of transcription (Tat) protein, specifically residues 48 to 57. This peptide facilitates the study of viral gene expression and replication by interacting with intracellular targets to enhance the transcriptional activity of HIV-1. TAT (48-57) is utilized in research applications focused on HIV pathogenesis, viral life cycle analysis, and the development of antiviral strategies. -
Competitive Peptide Against HiBiT
DrkBiT is a competitive peptide that targets HiBiT and is membrane-impermeable. It effectively binds to LgBiT, facilitating studies in the context of HIV-1 infection research. This peptide serves as a valuable tool for understanding viral dynamics and developing potential therapeutic strategies. -
Cell-penetrating Peptide/Delivery Carrier
TAT (47-57) GGG-Cys (Npys) is a cell-penetrating peptide that functions as an effective delivery carrier for therapeutic agents. This peptide facilitates the transport of conjugated drug molecules across biological membranes, enhancing their bioavailability. It is particularly suited for delivering MT1-MMP inhibitors and serves as a valuable tool in research on diseases linked to MT1-MMP activity, including cancer, arthritis, heart disease, and vascular disorders. -
Polypeptide
HIV-1 gag Protein p24 (194-210) is a polypeptide that serves as a critical target for immunoassays in HIV research. This peptide is essential for studying protein interactions and conducting functional analyses, particularly in the context of epitope mapping and agent development. Its application in peptide screening facilitates the identification of active peptides, aiding researchers in advancing their understanding of HIV biology and potential therapeutic strategies. -
Glycopeptide Antibiotic
Balhimycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to the D-alanine-D-alanine termini of precursor units. This compound exhibits potent antibacterial activity against strains of staphylococci and various anaerobic bacteria, making it valuable in the study of antibiotic resistance and infection management. Its application extends to research focused on the mechanisms of antibacterial action and the development of novel therapeutic agents. -
Herbicide
N-Acetyldemethylphosphinothricin tripeptide is a prodrug herbicide targeting amino acid biosynthesis in plants. Comprising the unique amino acid phosphinothricin and two alanine residues, this compound exhibits significant herbicidal activity by inhibiting the biosynthetic pathway of glutamine and glutamate. Its ability to penetrate bacterial cells via peptide uptake systems enhances its efficacy, making it a valuable tool in agricultural research and development related to herbicide mechanisms and plant growth regulation. -
Polypeptide
LL-37 SKE is a bioactive fragment of the human cathelicidin peptide LL-37, functioning primarily as an antimicrobial peptide. It exhibits significant antibacterial, antifungal, and antiviral properties, making it valuable for research in innate immunity and host defense mechanisms. LL-37 SKE is employed in studies exploring the modulation of immune responses and the development of therapeutic interventions for infectious diseases. -
Antibiotic/Antimicrobial Peptide
Aurein 3.2 is an antimicrobial peptide that exhibits potent antibiotic activity against a range of bacterial pathogens. In addition to its bactericidal properties, Aurein 3.2 demonstrates anticancer activity, making it a valuable compound for research in both infectious disease and cancer therapeutics. Its unique mechanism of action and dual functionality make it an important tool for exploring therapeutic applications in microbiology and oncology. -
Skin-Antimicrobial Peptide
Human β-defensin-2 (HβD-2) is a cysteine-rich cationic skin-antimicrobial peptide that primarily targets microbial pathogens. It exhibits significant antimicrobial activity against gram-negative bacteria and Candida species, while demonstrating limited efficacy against gram-positive Staphylococcus aureus. This peptide is valuable for research applications assessing its role in antimicrobial defense, particularly in models of colitis and skin-related disorders. -
Peptide
Urofollitropin is a recombinant form of follicle-stimulating hormone (FSH) targeting the follicle development pathway. It plays a crucial role in stimulating ovarian follicle maturation, making it essential for reproductive research and assisted reproductive technologies. Urofollitropin's biological activity supports studies in fertility treatments and the regulation of reproductive endocrinology. -
Antibacterial peptide
LL-37 GKE is an antibacterial peptide derived from the active domain of LL-37. It exhibits significant antibacterial activity, making it a valuable candidate for research in antibiotic development. LL-37 GKE’s properties offer potential applications in the study of infection control and the enhancement of antimicrobial therapies. -
Antimicrobial Peptide
Brevinin-1 is an antimicrobial peptide that targets microbial membranes. Isolated from the skin secretions of Rana esculenta, it demonstrates potent antibacterial and antifungal activity. Brevinin-1 is useful in microbiological studies and the development of novel antimicrobial treatments. -
Antibiotic/Antimicrobial Peptide
Aurein 3.1 is an antibiotic antimicrobial peptide that exhibits notable activity against Gram-positive bacteria. It demonstrates a minimum inhibitory concentration (MIC) of 80 μM against Micrococcus luteus and 50 μM against Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, and Bacillus subtilis. Aurein 3.1 is valuable for research applications focused on combating bacterial infections and studying antimicrobial mechanisms. -
Antibiotic/Antimicrobial Peptide
Aurein 3.3 is an antimicrobial peptide with potent antibiotic properties. It exhibits a dual mechanism of action, targeting bacterial membranes and disrupting cellular integrity. Additionally, Aurein 3.3 demonstrates anticancer activity, making it a valuable resource for research into antimicrobial therapeutics and cancer biology. Its unique properties allow for diverse applications in the study of microbial resistance and cancer treatment strategies. -
Antibiotic/Antimicrobial Peptide
Aurein 2.2 is an antimicrobial peptide that exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria including Staphylococcus aureus and S. epidermidis. Isolated from the skin secretions of L. aurea, Aurein 2.2 demonstrates potential as an effective antibiotic, making it a valuable tool for research in microbiology and antimicrobial therapy. Its unique mechanism of action and efficacy against resistant strains underline its relevance in the study of infection control and antibiotic development. -
Peptide Antibiotic
Angiotensin III antipeptide is a peptide antibiotic that inhibits the activity of angiotensin II, a key regulator in the renin-angiotensin system. It exhibits biological activity by modulating blood pressure and fluid balance, making it a valuable tool in cardiovascular and renal research. Its applications include studying the effects of angiotensin peptides on physiological processes and exploring potential therapeutic interventions in related diseases. -
Antibiotic/Antimicrobial Peptide
Aurein 2.6 is an antimicrobial peptide that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity, with minimum inhibitory concentrations (MIC) of 25 to 30 μM against various strains, including Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, and Bacillus subtilis. Aurein 2.6 is valuable for research applications involving antibiotic resistance studies and the development of new antimicrobial agents. -
Peptide Antibiotic
Clavanin A is a peptide antibiotic that disrupts the integrity of the cytoplasmic membrane in target cells. It demonstrates effective bactericidal activity against Micrococcus flavus, making it a valuable tool for studying bacterial membrane dynamics and antibiotic mechanisms. Researchers can utilize Clavanin A for investigations into microbial resistance and the development of new antimicrobial strategies. -
Antibacterial Peptide
KT2 is a cationic amphipathic antibacterial peptide that targets bacterial membranes. It exhibits potent antibacterial activity against E. coli O157:H7, demonstrating complete bactericidal effects and significant inhibition of biofilm formation. KT2 interacts with bacterial surface lipopolysaccharides (LPS) and penetrates lipid layers, facilitating its binding to DNA and other cytoplasmic components, making it a valuable reagent for research in antimicrobial therapies and biofilm-related studies. -
Neuropeptide
CART(62-76)(human,rat) targets neuropeptide pathways and functions as a neurotransmitter modulator. This peptide fragment (residues 62-76 of the CART peptide) influences the activity of the striatal noradrenergic system, as well as the corticostriatal and hypothalamic serotoninergic (5-HT) systems in the rat brain. CART(62-76) is valuable for research related to neurobiology, neuropharmacology, and the understanding of neuropeptide signaling in various physiological processes. -
Autoantigen Peptide
Myelin basic protein, MBP (68-86), is a peptide derived from the 68th to 86th amino acid residues of the myelin basic protein sequence. This peptide functions as an autoantigen, initiating immune responses that can lead to the destruction of myelin. MBP (68-86) is utilized in the experimental autoimmune encephalomyelitis (EAE) animal model, making it a valuable tool for investigating the immunological mechanisms involved in multiple sclerosis (MS). -
Bioactive Peptide
PKCε (85-92) is a bioactive peptide that selectively activates epsilon protein kinase C (e-PKC). This peptide effectively induces MARCKS phosphorylation in wild-type cells, demonstrating its role in signaling pathways related to cellular function. However, it does not influence MARCKS phosphorylation in cells derived from knockout mice, indicating its specificity. PKCε (85-92) is valuable for research applications focused on PKC signaling and the study of related cellular processes. -
PKC Substrate
EGFR Peptide is a selective substrate for Protein Kinase C (PKC), facilitating the measurement of PKC activity in various biological contexts. This peptide is instrumental in studies examining PKC's role in cellular signaling pathways, making it a valuable tool for researchers exploring cancer biology, cell proliferation, and differentiation processes. Its specific interaction with PKC allows for accurate assessments of enzyme activity, contributing to a deeper understanding of PKC-mediated signaling mechanisms. -
Peptide
[Glu27]-PKC (19-36) is a peptide that serves as an inactive control for protein kinase C (PKC) (19-36). As a pseudosubstrate peptide inhibitor, it is designed to maintain PKC in an inactive state without the presence of allosteric activators, such as phospholipids. This reagent is applicable in studies examining the regulation of PKC activity and its role in various cellular signaling pathways. Researchers can utilize [Glu27]-PKC (19-36) to assess the impact of active and inactive states of PKC in experimental setups. -
Peptide
Protein Kinase C β Peptide is a peptide fragment derived from Protein Kinase Cβ, which plays a critical role in regulating vascular function. It has been shown that hyperglycemia negatively impacts endothelium-derived nitric oxide production, leading to impaired vasodilation. The inhibition of Protein Kinase Cβ can counteract the reduction in endothelium-dependent vasodilation that occurs during acute hyperglycemia, making this peptide a valuable tool for research into vascular complications associated with diabetes and metabolic disorders. -
Bioactive Peptide
KRPpSQRHGSKY-NH2 is a bioactive peptide that serves as a phosphorylated substrate for protein kinase C (PKC). This compound is utilized in research applications to study signaling pathways and phosphorylation events mediated by PKC. Its role in cellular processes makes it valuable for investigating various biological functions and potential therapeutic targets. -
PKC βII V5 Peptide
Protein Kinase C (660-673) is a peptide derived from the PKC βII isoform, specifically designed to exhibit RACK1-binding affinity. This peptide serves as a valuable tool for studying the interactions of PKC βII with RACK1, providing insights into signaling pathways mediated by Protein Kinase C. Its unique structural properties make it suitable for investigating PKC βII's role in cellular processes, including proliferation and differentiation. -
PKC Pseudosubstrate Inhibitor
Protein Kinase C (19-35) Peptide serves as a pseudosubstrate inhibitor of Protein Kinase C (PKC). By potentially blocking the substrate-binding site within the kinase domain, this peptide renders the cytoplasmic form of PKC inactive. This inhibition is valuable for investigating PKC-related signaling pathways and understanding its role in various cellular processes. Its applications extend to research focused on cell proliferation, differentiation, and apoptosis associated with PKC activity. -
PKCδ Substrate
PKCδ Peptide Substrate is a highly specific substrate that targets the δ isoform of Protein Kinase C (PKCδ). Featuring the amino acid sequence corresponding to residues 422-443 of murine eEF-1α and incorporating Thr-431, this peptide supports detailed studies of PKCδ activity. It is suitable for a variety of research applications, including kinase assays and understanding PKCδ's role in cellular signaling pathways. -
Inhibitor Peptide
pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively targets and disrupts the interactions of Protein Interacting with C kinase 1 (PICK1). This compound is known to exert opposing effects on synaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) function relative to PICK1 expression. It serves as a valuable tool for studying synaptic signaling pathways and understanding the role of PICK1 in synaptic plasticity and related neurobiological processes. -
MBP Peptide
Ac-MBP (4-14) Peptide is an acetylated derivative of the myelin basic protein (MBP) sequence encompassing amino acids 4 to 14. This peptide serves as a selective substrate for protein kinase C (PKC), facilitating accurate biochemical assays. Ac-MBP (4-14) Peptide is suitable for PKC activity assays in crude extracts, allowing for the assessment of PKC function without the need for prior purification steps to remove interfering kinases or phosphatases. -
PKC Inhibitor
[Ala107]MBP(104-118) is a noncompetitive inhibitor of protein kinase C (PKC), exhibiting IC50 values between 46-145 μM. This peptide is utilized in research to study PKC activity and its role in cellular signaling pathways. Its ability to selectively inhibit PKC makes it a valuable tool in investigating the implications of PKC in various disease states and pharmacological interventions. -
Neuropeptide
Neuropeptide DF2 is a neuropeptide derived from crayfish, specifically a member of the DRNFLRFamide family. It enhances neurotransmitter release and increases the amplitude of excitatory post-synaptic potentials (EPSP) via activation of calcium/calmodulin-dependent protein kinase pathways. This compound is valuable for research in neurobiology and synaptic transmission. -
Peptide
Protein Kinase C γ Peptide is a bioactive peptide fragment derived from Protein Kinase Cγ, which plays a crucial role in cellular signaling pathways. This peptide is involved in the regulation of nuclear import mechanisms associated with recessive ataxia-related aprataxin and has implications in the study of dominant ataxia disorders. It is a valuable tool for researchers exploring the molecular mechanisms underlying ataxia and related neurodegenerative conditions. -
Peptide
Pep2m, myristoylated is a cell-permeable peptide that targets protein kinase ζ (PKMζ). This compound is known to disrupt the interactions between N-ethylmaleimide-sensitive factor (NSF) and glutamate receptor subunit 2 (GluR2), providing valuable insights into the roles of PKMζ in cellular signaling. Pep2m, myristoylated is useful for researching synaptic transmission and plasticity, as well as studying the molecular mechanisms underlying memory and learning processes. -
PKC Inhibitor
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a selective inhibitor of protein kinase C (PKC), exhibiting an IC50 of 75 μM. This compound effectively inhibits the induction of the IL-2 receptor and production of IL-2 in the Jurkat human leukemic cell line. It can be utilized in research focused on understanding PKC-related signaling pathways and their role in immune responses. -
Protein Kinase C Peptide
Protein Kinase C α Peptide (TFA) is a synthetic peptide derived from Protein Kinase C alpha, which functions as a lipid-dependent serine/threonine protein kinase. This reagent plays a critical role in modulating various cellular processes such as cell survival, proliferation, differentiation, migration, and adhesion. It is widely utilized in research applications exploring signaling pathways and cellular responses pertinent to cancer and other diseases. -
PKC Activator
Protein Kinase C (530-558) is a potent activator of Protein Kinase C (PKC). This peptide fragment has been shown to significantly inhibit osteoclastic bone resorption, making it valuable for research on bone metabolism and related disorders. Its specific activation of PKC can provide insights into the signaling pathways involved in various cellular processes, contributing to studies in cell biology and pharmacology. -
Peptide
FKKSFKL-NH2 is a selective peptide targeting protein kinase C (PKC). This compound is valuable for studying PKC-mediated signaling pathways and its involvement in various biochemical processes. Researchers can utilize FKKSFKL-NH2 to explore its potential roles in cell signaling, proliferation, and differentiation, contributing to a deeper understanding of PKC-related functions in cellular biology. -
PKC Substrate
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) serves as a selective substrate for phosphorylation by protein kinase C (PKC). This reagent is useful for assessing PKC activity in various biological contexts, providing insights into signaling pathways involving PKC and glycogen metabolism. Researchers can utilize this substrate to elucidate the regulatory mechanisms of PKC in cellular processes. -
Signal Accepts Peptide
Protein Kinase C Peptide Substrate is specifically designed to act as a substrate for Protein Kinase C, a crucial player in cellular signal transduction. This substrate participates in the phosphorylation of serine and threonine residues in target proteins, modulating various cellular processes in response to second messengers. Its key biological activities include regulation of nervous, endocrine, exocrine, inflammatory, and immune responses. This reagent is valuable for research applications aimed at understanding signaling pathways and the functional roles of Protein Kinase C in cellular physiology. -
BMP Encephalitogenic Epitope
Ac-MBP (1-11) is a synthetic peptide that represents the primary encephalitogenic epitope derived from myelin basic protein (MBP). This peptide is critical for studies on multiple sclerosis and other autoimmune disorders, as it plays a significant role in immune response and T cell activation. Ac-MBP (1-11) is widely utilized in research to understand the mechanisms of demyelination and to explore potential therapeutic interventions. -
Bioactive Peptide
PKCd (8-17) is a bioactive peptide derived from the V1 domain of protein kinase C (PKC)d. This peptide effectively inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Its inhibitory effects on PKCd contribute to reduced ischemic damage in cardiac and cerebral cells, promote fibroblast proliferation, and inhibit graft coronary artery disease in murine models, making it valuable for research in cardiac and cerebrovascular conditions. -
PKA Substrate
Phosphate acceptor peptide is a specific substrate for cyclic AMP-dependent protein kinase (PKA), facilitating the study of phosphorylation processes. Additionally, it exhibits weak inhibitory activity against protein kinase C (PKC), making it useful in exploring the mechanisms of kinase signaling pathways. This reagent is applicable in various biochemical assays aimed at understanding cellular signaling and regulation. -
PKCβII Inhibitor
PKCβII Peptide Inhibitor I is a selective inhibitor of Protein Kinase C beta II (PKCβII). This peptide demonstrates significant cardioprotective effects in rat models of ischemia/reperfusion injury, making it a valuable tool in cardiovascular research. Additionally, it has been shown to prevent vascular endothelial dysfunction, highlighting its potential applications in studying vascular health and related pathologies.
