Neuropeptide AF1 is a FMRFamide-like neuropeptide that demonstrates significant neuromodulatory activity in nematodes. Isolated from head extracts of Ascaris suum, Neuropeptide AF1 effectively abolishes slow membrane potential oscillations in both ventral and dorsal inhibitory motoneurons, while selectively decreasing their input resistances. This neuropeptide is useful for studying locomotion and inhibitory signaling in nematodes, making it a valuable tool for researchers investigating neurobiology and muscle control in invertebrates.
Neuropeptide AF1 is a FMRFamide-like neuropeptide that demonstrates significant neuromodulatory activity in nematodes. Isolated from head extracts of Ascaris suum, Neuropeptide AF1 effectively abolishes slow membrane potential oscillations in both ventral and dorsal inhibitory motoneurons, while selectively decreasing their input resistances. This neuropeptide is useful for studying locomotion and inhibitory signaling in nematodes, making it a valuable tool for researchers investigating neurobiology and muscle control in invertebrates.
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