NG2 binding peptide

Catalog No.: B19430
NG2 Targeting Peptide
NG2 Binding Peptide is a selective ligand that targets the NG2 proteoglycan, identified through phage display technology. This peptide engages specifically with NG2 binding sites, facilitating precise targeting of tumor-associated angiogenesis in both in vitro and in vivo models. Demonstrating notable homing capabilities in wild-type tumor-bearing mice, it has no localization in NG2 knockout models, underscoring its specificity. Due to the restricted expression of NG2 in certain tissues, NG2 Binding Peptide is suitable for applications in tumor-targeted therapy, drug delivery, and molecular imaging diagnostics.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNG2 Binding Peptide is a selective ligand that targets the NG2 proteoglycan, identified through phage display technology. This peptide engages specifically with NG2 binding sites, facilitating precise targeting of tumor-associated angiogenesis in both in vitro and in vivo models. Demonstrating notable homing capabilities in wild-type tumor-bearing mice, it has no localization in NG2 knockout models, underscoring its specificity. Due to the restricted expression of NG2 in certain tissues, NG2 Binding Peptide is suitable for applications in tumor-targeted therapy, drug delivery, and molecular imaging diagnostics.
Product Information
Catalog NumB19430
FormulaC40H69N15O14S
Molecular Weight1016.13
CAS Number241478-23-9
SequenceThr-Ala-Ala-Ser-Gly-Val-Arg-Ser-Met-His
Sequence shorteningTAASGVRSMH
SMILES[C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)C)=O)C)=O)CO)=O)=O)[C@H](C)C)=O)(C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(O)=O)=O)CCSC)=O)CO)=O)CCCNC(=N)N
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