Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
D-Glyceric acid sodium is the sodium salt of D-Glyceric acid, an endogenous metabolite found in human urine. This compound plays a significant role in metabolic pathways and serves as a valuable research tool for investigating conditions such as primary hyperoxaluria type I and glutaric acidemia type II. Its application extends to studying metabolic disorders and understanding related biochemical processes. -
Endogenous Metabolite
3-Phenylbutyric acid is an endogenous metabolite known for its role in various metabolic pathways. This compound exhibits potential as a selective agent for isolating Rhodococcus rhodochrous PB1, facilitating research into microbial biotechnology and environmental sciences. Its unique structure enables exploration in studies related to phenylpropanoid metabolism and microbial interactions in compost environments. -
Endogenous Metabolite
N-Lactylleucine is an endogenous metabolite associated with metabolic processes in the human body. It plays a notable role in identifying patients with intermediate maple syrup urine disease, a disorder impacting amino acid metabolism. This compound is valuable for research applications focused on metabolic disorders and the biochemical pathways related to amino acid regulation. -
Endogenous Metabolite
N-Lactylvaline is an endogenous metabolite primarily associated with metabolic pathways related to branched-chain amino acids. It has been identified in patients with intermediate maple syrup urine disease, serving as a potential biomarker for diagnosing metabolic disorders. This compound can be utilized in research applications aimed at understanding metabolic derangements and developing therapeutic interventions. -
Endogenous Metabolite
Glutathione sulfonate (S-Sulfoglutathione) is a competitive inhibitor of glutathione S-transferase, targeting its substrate binding site, which significantly impacts the enzyme's catalytic activity. This endogenous metabolite is known for its multifunctional properties, including the inhibition of angiogenesis and tumor growth. It plays a crucial role in the detoxification of various exogenous and endogenous compounds and is valuable for research applications focusing on cancer biology and metabolic processes. -
Endogenous Metabolite
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that serves as a critical component of cell membranes. This phospholipid plays a significant role in modulating cellular signaling pathways and contributing to membrane fluidity. It is utilized in research applications involving lipid metabolism, membrane biology, and the study of lipid-mediated signaling processes. -
Endogenous Metabolite
3-Hydroxypropionic acid sodium is an endogenous metabolite involved in various biochemical pathways. It serves as a versatile building block in chemical synthesis, particularly in the production of polymers and other complex molecules. This compound is crucial for research applications focused on metabolic pathways and synthetic biology, enhancing the understanding of metabolic processes and enabling the development of innovative materials. -
Endogenous Metabolite
3-Oxochenodeoxycholic acid is an endogenous metabolite that plays a role in several physiological processes. As a potential biomarker, it may assist in the diagnosis of certain conditions, including COVID-19. This compound is primarily utilized in research focused on metabolic pathways and disease state characterization. -
Endogenous Metabolite
Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that serves as an endogenous metabolite. It acts as a precursor in the synthesis of guanosine monophosphate (GMP) and adenosine monophosphate (AMP), playing a pivotal role in nucleotide metabolism. This compound is utilized in various research applications, including studies of taste perception and metabolism in cellular processes. -
Endogenous Metabolite
PAz-PC (Azelaoyl Phosphatidylcholine) is an endogenous metabolite derived from oxidized low-density lipoprotein (oxLDL) particles. It contains a unique oxidized short-chain fatty acid remnant at the sn-2 position, contributing to its cytotoxic and pro-atherogenic properties. PAz-PC is a critical structural component in oxLDL and is valuable in research exploring lipid metabolism, atherosclerosis, and cardiovascular disease mechanisms. -
Endogenous Metabolite
5-Hydroxymethylcytosine (5hmC) is an oxidized derivative of 5-methylcytosine found within mammalian DNA. Generated through an enzymatic process involving the Ten-eleven translocation (TET) enzymes TET1, TET2, and TET3, 5hmC serves as an important marker for investigating the dynamic processes of DNA demethylation and gene transcription. Its presence is particularly significant in the study of conditions such as non-small cell lung cancer, neurodegenerative diseases like Alzheimer’s and Parkinson’s, and various hematological malignancies, including acute myeloid leukemia and myelodysplastic syndromes. -
Endogenous Metabolite
1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC is an endogenous metabolite and a plasmalogen, featuring 1(Z)-octadecenoic acid at the sn-1 position and arachidonic acid at the sn-2 position. It exhibits significant singlet oxygen scavenging activity in cell-free assays, making it valuable for research into oxidative stress and related biological processes. This compound has potential applications in studies focusing on lipid metabolism, cell signaling, and neuroprotection. -
Endogenous Metabolite
2,8-Dihydroxyadenine is an endogenous metabolite with a crucial role in the diagnosis of adenine phosphoribosyltransferase (APRT) deficiency. Its accumulation can lead to the formation of urinary crystals and kidney stones, making it significant in renal pathology studies. This compound is valuable for investigating metabolic disorders and understanding crystal-induced nephropathy. -
Endogenous Metabolite
2-Methylbenzaldehyde is a naturally occurring metabolite that functions primarily as a signaling molecule in various biochemical pathways. It is involved in the regulation of metabolic processes and plays a role in the synthesis of aromatic compounds. This compound is useful in research applications related to metabolic profiling, enzymatic studies, and the investigation of cellular signaling mechanisms. -
Endogenous Metabolite
(S)-Nornicotine is an endogenous metabolite of nicotine with implications in nicotine addiction and neurobiological research. It serves as a valuable tool for studying the pharmacological effects of nicotine and its derivative compounds. Its role in receptor modulation and potential influence on neurotransmitter systems makes it relevant for investigations into smoking cessation and substance use disorders. -
Endogenous Metabolite
(E)-Oct-2-enoic acid is an endogenous metabolite that plays a role in various biological processes. This compound is involved in metabolic pathways and can serve as a valuable tool in research focused on metabolic regulation and physiological functions. Its unique properties make it suitable for studies investigating the impact of metabolites on cellular signaling and related activities. -
Endogenous Metabolite
Fructosyl-lysine dihydrochloride is an amadori glycation product that arises from the reaction between glucose and lysine via the Maillard reaction. This compound serves as a precursor to glucosepane, a significant lysine–arginine protein cross-link implicated in diabetic pathology. Its measurement can be valuable for assessing glycemic control and may serve as a biomarker for the early detection of diabetes. Research applications include studying glycation processes and their impact on protein function and structure in various biological systems. -
Endogenous Metabolite
3-Methylindolin-2-one is an endogenous metabolite known for its involvement in various biochemical pathways. This compound plays a critical role in biological processes and is utilized in research focused on metabolic studies and the exploration of cellular functions. Its applications extend to studies in pharmacology and toxicology, contributing to the understanding of drug metabolism and physiological responses. -
Endogenous Metabolite
5-Methoxy-5-oxopentanoic acid is an endogenous metabolite known to play a role in various metabolic pathways. It has been implicated in regulating energy metabolism and may influence physiological processes related to metabolic disorders. This compound is suitable for research applications focused on understanding metabolic functions and the role of endogenous metabolites in biological systems. -
Endogenous Metabolite
Trans-2-butene-1,4-dicarboxylic acid is an endogenous metabolite with significant roles in various biochemical pathways. This compound is of interest for studying metabolic processes and cellular responses, particularly in the context of energy metabolism and biosynthesis. Its unique structure and biological activity make it a valuable reagent for research applications in metabolomics and related fields. -
Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid and serves as an endogenous metabolite. This compound plays a significant role in lipid metabolism and may influence various physiological processes. It is commonly used in research to study fatty acid biosynthesis, metabolic pathways, and their implications in health and disease. -
Endogenous Metabolite
3-(2,4-Dihydroxyphenyl)propanoic acid is a competitive inhibitor of tyrosinase, primarily targeting the conversion of L-Tyrosine and DL-DOPA. It exhibits potent inhibitory effects, with an IC50 of 3.02 μM and a Ki of 11.5 μM. This compound is valuable in research applications focused on melanogenesis, skin pigmentation, and the study of related metabolic pathways. -
Endogenous Metabolite
1-Palmitoyl-sn-glycerol 3-phosphate sodium salt is an endogenous metabolite that serves as a key regulator in lipid metabolism. This compound is particularly relevant in the study of non-alcoholic fatty liver disease, where it can aid in understanding lipid dysregulation and related pathological processes. Its role in cellular signaling makes it a valuable tool for research in metabolic disorders. -
Endogenous Metabolite
Inosinic acid disodiumhydrate (1:2:X) is an endogenous metabolite known to play a significant role in cellular energy transfer and nucleotide synthesis. This compound is primarily utilized as a flavor enhancer due to its umami taste profile and has applications as a dietary supplement to enhance meat quality in livestock, particularly in pigs. Its ability to influence metabolic pathways makes it a valuable reagent for research in nutrition and food science. -
Endogenous Metabolite
Imidazol-1-yl-acetic acid is an endogenous metabolite that plays a significant role in various biological processes. It is involved in the regulation of cellular signaling pathways and metabolism. This reagent is valuable for research applications focused on metabolic studies, as well as the exploration of its role in physiological and pathological conditions. -
Endogenous Metabolite
5α-Cholestan-3-one is an endogenous metabolite primarily involved in cholesterol metabolism. This compound serves as a crucial intermediate in the biosynthesis of steroid hormones and is important for investigating lipid-related metabolic pathways. Its biological activity is significant in studies related to metabolic disorders and hormonal regulation. -
Endogenous Metabolite
3-Methyl-2-buten-1-ol is an endogenous metabolite that modulates physiological processes in various biological systems. This compound exhibits potential weight reduction effects, as evidenced by studies demonstrating its efficacy in animal models. It is primarily utilized in research applications related to metabolism and may hold significance for studies on fragrance compounds due to its presence in pine trees. -
Endogenous Metabolite
19-Hydroxyandrost-4-ene-3,17-dione serves as a substrate for the enzymes Corticotropin-lipotropin and Cytochrome P450 19A1. This endogenous metabolite plays a crucial role in steroidogenesis and is valuable in studies of adrenal and gonadal function. Its utility extends to research on hormone biosynthesis and the physiological effects of androgens and estrogens. -
Endogenous Metabolite
D-Threitol functions as an endogenous metabolite and plays a critical role in cryoprotection. Its primary biological activity includes acting as an antifreeze agent in organisms such as the Alaskan beetle Upis ceramboides. This compound is of interest in studies investigating metabolic adaptations to extreme cold environments and cellular responses to stress conditions. -
Endogenous Metabolite
Ac-DL-Trp-OH is an endogenous metabolite that serves as a precursor in the biosynthesis of various tryptophan-derived compounds. This compound is utilized in studies focused on metabolic pathways and neurotransmitter synthesis, particularly in relation to serotonin and melatonin production. Its application extends to research involving tryptophan metabolism and related phenotypic effects in biological systems. -
Endogenous Metabolite
L-Cysteic acid monohydrate is an endogenous metabolite and the oxidation product of L-cystine. It serves as a substrate for glutamate decarboxylase (GADCase) and cysteine sulfinic acid decarboxylase (CADCase II), playing a crucial role in neurotransmitter synthesis. This compound is valuable for research into amino acid metabolism and neurological function. -
Endogenous Metabolite
3-Furanoic acid is an endogenous metabolite known for its anti-inflammatory properties. It and its derivatives can modulate inflammation-related signaling pathways and inhibit the proliferation of synovial fibroblasts, thereby exerting significant immunomodulatory effects. This compound is valuable for research in inflammation, autoimmune disorders, and related therapeutic developments. -
Endogenous Metabolite
3-Methoxybenzoic acid is an endogenous metabolite that exhibits the ability to form complexes with metal ions, including europium (III) and gadolinium (III). It is known to undergo metabolism by anaerobic bacteria primarily through an O-demethylation mechanism. This compound is utilized in studies involving metal ion coordination and investigations into microbial metabolic pathways. -
Endogenous Metabolite
Cyclohexaneacetic acid serves as an endogenous metabolite involved in the metabolic pathways of n-alkylcyclohexanes (nACH) in microorganisms. This compound can be metabolized into monohydroxycyclohexaneacetic acids by various strains of Chlorella pyrenoidosa. Its biological activity makes it relevant for studies focusing on microbial metabolism and environmental biochemistry. -
Endogenous Metabolite
DL-Glutamic acid is the conjugate acid of glutamic acid, functioning as a key endogenous metabolite. It plays a critical role in various biochemical pathways, including neurotransmission and metabolic processes. Compared to the α and β polymorphs of L-Glutamic acid, DL-Glutamic acid exhibits enhanced stability, making it a valuable reagent for research applications in biochemistry and neurobiology. -
Endogenous Metabolite
Isomaltulose hydrate is an endogenous carbohydrate metabolite. It serves as a source of energy through enzymatic hydrolysis and plays a role in metabolic processes. This compound is useful in research related to energy metabolism, glycemic response, and the exploration of dietary carbohydrates' impact on health. -
Endogenous Metabolite
Undecanedioic acid is an endogenous metabolite that plays a significant role in the structural integrity of intercellular matrix macromolecules, particularly elastin. Its biological activity is essential for studying extracellular matrix dynamics, cellular interactions, and tissue elasticity. This compound is valuable in research applications focusing on connective tissue disorders and metabolic studies related to elastin synthesis and degradation. -
Endogenous Ceramide
C14 Ceramide (d18:1/14:0) is an endogenous ceramide synthesized by ceramide synthetase 6. This compound plays a critical role in various cellular processes, including apoptosis and inflammation. It holds significant potential for research applications in the fields of neurodegenerative diseases, such as Parkinson's disease, and metabolic disorders like diabetes, providing insights into lipid signaling pathways and their implications in disease mechanisms. -
Endogenous metabolites
AAMU (5-Acetylamino-6-amino-3-methyluracil) is a key endogenous metabolite of caffeine, predominantly found in human biological systems. This compound is important for studying caffeine metabolism and its biological effects. AAMU serves as a valuable biomarker in research focused on caffeine's role in various physiological processes and may aid in understanding its impact on health. -
Endogenous Metabolite
Oxaloacetic acid-13C4 is the stable isotopically labeled form of oxaloacetic acid, a key endogenous metabolite. This compound plays a critical role as a metabolic intermediate in the citric acid cycle, gluconeogenesis, urea cycle, glyoxylate cycle, and various biosynthetic pathways, including amino acid and fatty acid synthesis. Oxaloacetic acid-13C4 is essential for tracing metabolic dynamics in biological research and can be utilized in studies involving metabolic flux analysis and the assessment of metabolic pathways. -
Endogenous Metabolite
H-Trp-NH2.HCl, a derivative of tryptophan, functions primarily as an endogenous metabolite involved in various biochemical pathways. It plays a significant role in metabolic processes and can be utilized in research applications focused on amino acid metabolism and neurotransmitter synthesis. This compound is valuable for studies investigating the physiological effects of tryptophan derivatives in cellular and molecular biology. -
Endogenous Metabolite
Ethyl arachidonate is an esterified form of arachidonic acid, functioning as a lipophilic endogenous metabolite. It serves as a source of exogenous arachidonate in dietary regimens and cell culture, facilitating studies on fatty acid metabolism. Notably, ethyl arachidonate is the predominant fatty acid ethyl ester found in the brains of individuals with alcohol intoxication, making it relevant for research into alcohol-related neurobiology. -
Endogenous Metabolite
Decyl aldehyde is a ten-carbon aldehyde that functions as a substrate for bacterial luciferase. This compound serves as an important endogenous metabolite in various biological systems. It is utilized in research applications focused on bioluminescence and metabolic studies, offering insights into cellular processes and enzyme activity. -
Endogenous Metabolite
Estromustine is the active metabolite of Estramustine phosphate, primarily targeting the mutant androgen receptor (m-AR). It demonstrates an EC50 of 2.6 μM in LNCaP prostate cancer cells and exhibits cytotoxicity with an IC50 of 9.73 μM. This compound is valuable for research focused on androgen receptor mutations and their role in prostate cancer therapeutics. -
Endogenous Estrogen Precursor
β-Estradiol 17-acetate serves as an endogenous estrogen precursor, demonstrating significant cell viability and proliferation-enhancing properties. This compound promotes adhesion and proliferation in freshly isolated and revived female-derived human brain microvascular endothelial cells while reversing decreased viability in revived male-derived counterparts. β-Estradiol 17-acetate exhibits the microvascular protective effects of estrogen, facilitating the culture of non-tumor human brain microvascular endothelial cells in vitro for up to two months post-cryopreservation. In the human skin and other models, it is biotransformed into β-estradiol through hydrolase activity. -
Endogenous Protein Marker
N-TCO-L-lysine is a non-canonical amino acid featuring a trans-cyclooctene (TCO) bioorthogonal reactive linker. This compound is engineered for the selective labeling of endogenous proteins through a bioorthogonal click reaction with SiR-Tz, facilitating site-specific incorporation. N-TCO-L-lysine is valuable for super-resolution and live-cell imaging applications, enabling researchers to study the dynamics and localization of proteins in their native environments. -
Endogenous metabolites
2α-Methyl androsterone is an anabolic androgenic steroid that acts as a metabolite of mesterolone and drostanolone. It exhibits key biological activities related to androgen receptors, playing a significant role in various androgen-dependent processes. This compound is primarily utilized in research applications focused on steroid hormone metabolism and the development of anabolic therapies. -
Endogenous Metabolite
G-4'G-7S is an endogenous metabolite of genistein that primarily targets estrogen receptors. This compound exhibits estrogenic activity, making it valuable for research into mechanisms of hormone action and the role of phytoestrogens in biological systems. Its study may provide insights into the effects of dietary components on estrogen signaling and related health outcomes. -
Endogenous Autacoid
Adenosine-15N5 is a 15N-labeled analogue of adenosine, an endogenous autacoid that primarily targets four G protein-coupled receptors: A1, A2A, A2B, and A3. This compound plays a critical role in various physiological processes, influencing neuronal signaling, vascular tone, platelet aggregation, and the regulation of blood cells. Its applications in research include studying cellular signaling pathways, metabolic regulation, and tissue response to physiological challenges. -
Endogenous metabolites
11β-Prostaglandin F1β is an endogenous metabolite and a stereoisomer of PGF1α, characterized by inverted hydroxyl groups at C-9 and C-11. This compound plays a significant role in modulating various physiological processes, including inflammation and reproductive functions. It is utilized in research applications focused on prostaglandin signaling pathways and their impact on cellular responses in various biological systems.
