Nucleoside Antimetabolite/Analog

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  1. Nucleoside Analog

    pApG is a nucleoside analog that serves as a monomeric building block for nucleic acid synthesis. It is utilized in biochemical research for the development of oligonucleotides and the study of nucleic acid interactions. Additionally, pApG may assist in the investigation of enzyme activities and the modulation of RNA and DNA functionality in various biological systems.
  2. Purine Nucleoside Analog

    3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is useful in cancer research, particularly for studies investigating therapeutic strategies against lymphoid cancers.
  3. Nucleoside Analog

    5-Formyl-CTP is a nucleoside analog that serves as a crucial monomeric building block for nucleic acid synthesis. It plays a key role in various molecular biology applications, including the construction of DNA and RNA sequences. This compound is valuable in research settings focused on gene expression, genetic engineering, and the development of synthetic biology tools.
  4. Nucleoside Analog

    3'-P-dTTP is a nucleoside analog that serves as a vital component for nucleic acid synthesis. Its incorporation into DNA strands facilitates the study of replication processes and the development of synthetic nucleic acids. 3'-P-dTTP is essential for exploring enzyme kinetics and for applications in gene editing and molecular biology research.
  5. Nucleoside Analog

    2′-O-MOE-AMP is a nucleoside analog that serves as a building block for oligonucleotide synthesis. Its modification enhances the stability and efficiency of oligonucleotides, making it valuable in various molecular biology applications. This compound is particularly useful in the development of therapeutics and diagnostic tools, as well as in studies involving gene expression and regulation.
  6. Nucleoside Analog

    Thymidine 5′-diphosphate disodium is a nucleoside analog that serves as an essential monomer for nucleic acid synthesis. It plays a critical role in DNA and RNA polymerization processes, facilitating the incorporation of thymidine into nucleic acid strands. This reagent is particularly valuable in molecular biology research, synthetic biology, and the development of nucleic acid-based therapeutics.
  7. Nucleoside Analog

    5-Azdio-UTP is a nucleoside analog that serves as a monomeric building block for nucleic acid synthesis. Its unique structure allows for incorporation into RNA molecules, providing valuable insights into RNA biology and function. This reagent is useful in research applications such as studying RNA transcription and the development of RNA-based therapeutics.
  8. Nucleoside Analog

    Peracetylated GalNAc PEG linker-azide is a versatile nucleoside analog designed for efficient nucleic acid synthesis. This compound features a peracetylated galactosamine moiety linked to a polyethylene glycol (PEG) azide, facilitating conjugation reactions. It is particularly valuable in the development of glyco-nucleic acid constructs and other bioconjugation applications.
  9. Nucleoside Analog

    3'-O-Phthalimido-2'-dA is a nucleoside analog that serves as a versatile monomeric substrate in nucleic acid synthesis. Its structural modifications facilitate the incorporation of modified nucleotides into oligonucleotides, enhancing their stability and functionality. This reagent is essential for applications in molecular biology, particularly in the design and development of oligonucleotide-based therapeutics and probes.
  10. Nucleoside Analog

    DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-phosphoramidite is a nucleoside analog utilized in the synthesis of oligonucleotides. This phosphoramidite serves as a key building block, enabling the incorporation of modified nucleotides into nucleic acid sequences. It is particularly valuable in research applications involving the development of therapeutics and diagnostics, where enhanced stability and specificity are desired.
  11. Nucleoside Analog

    2',3'-Dideoxy-C(Ac) is a nucleoside analog that serves as a crucial building block for nucleic acid synthesis. This compound inhibits RNA and DNA polymerases by lacking the necessary hydroxyl groups for elongation, making it useful in studying viral replication and cellular processes. Its application extends to research in antiviral drug development, gene expression studies, and the exploration of nucleic acid structure and function.
  12. Nucleoside Analog

    2'-O-MOE-rC(Ac) is a modified nucleoside analog designed to enhance the stability and efficacy of nucleic acids. This compound serves as a valuable monomeric building block in the synthesis of RNA and DNA oligonucleotides, facilitating improved hybridization and cellular uptake. Its unique chemical structure promotes resistance to nucleases, making it ideal for various applications in antisense oligonucleotide research and RNA interference studies.
  13. Nucleoside Analog

    N6-Methyl-dATP is a nucleoside analog that serves as a crucial building block for nucleic acid synthesis. It exhibits unique properties that can enhance the fidelity and efficiency of enzymatic reactions in molecular biology applications. This compound is valuable for researchers studying DNA replication, transcription, and the incorporation of modifications in nucleic acid sequences.
  14. Nucleoside Analog

    2'-F-iBu-G (2′-Deoxy-2′-fluoro-N-isobutyrylguanosine) is a nucleoside analog that serves as a valuable building block in the synthesis of oligoribonucleotides. Its structural modifications enhance nuclease resistance and improve cellular uptake, making it a useful reagent in ribonucleic acid (RNA) research. This compound is suitable for various applications, including studies in RNA biology and the development of therapeutic oligonucleotides.
  15. Nucleoside Analog

    3'-O-Phthalimido-2'-dG is a nucleoside analog that serves as a critical monomeric building block for nucleic acid synthesis. It is utilized in various molecular biology applications, including the preparation of oligonucleotides and the development of modified nucleic acids. Its structural modifications enable enhanced stability and functionality in nucleic acid formulations, making it an essential reagent for researchers in genomics and related fields.
  16. Nucleoside Analog

    Im-GDP is a monomeric nucleoside analog utilized in nucleic acid synthesis. It serves as a building block for the formation of RNA and DNA molecules, facilitating the study of genetic material and its various functions. Im-GDP is particularly useful in research applications involving oligonucleotide synthesis, genetic engineering, and molecular biology.
  17. Nucleoside Analog

    DMTr-2'-O-Me-pseudoU-3'-CE-phosphoramidite is a nucleoside analog designed for the synthesis of RNA and DNA. This phosphoramidite monomer provides enhanced stability and modified properties, making it suitable for the development of oligonucleotides with specific functionalities. Applications include research on RNA interference, antisense oligonucleotide therapies, and the study of RNA structure and function.
  18. Nucleoside Analog

    5'-DMTr-2'-O-MOE-rG(iBu)-3'-succinate TEA is a nucleoside analog designed for use in nucleic acid synthesis. Its structural properties facilitate the incorporation of modified nucleotides into oligonucleotides, enhancing their stability and performance. This reagent is ideal for applications in molecular biology, including the development of therapeutics and tools for gene modulation.
  19. Nucleoside Analog

    Abasic Succinate is a nucleoside analog designed for use in nucleic acid synthesis. This monomeric raw material serves as a key building block in the construction of nucleic acid sequences, enabling research applications in gene editing, molecular cloning, and the development of nucleic acid-based therapeutics. Its unique structure allows for the modification and study of DNA and RNA interactions.
  20. Nucleoside Analog

    3'-O-TBDMS-2'-dA(Bz) is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. It is widely utilized in the development of oligonucleotides, enabling advancements in genetic research, medicinal chemistry, and the synthesis of novel therapeutics. This compound provides enhanced stability and versatility in reaction conditions, facilitating the exploration of various biochemical pathways.
  21. Nucleoside Analog

    2'-Azido-dCTP is a nucleoside analog that serves as a building block in nucleic acid synthesis. This compound is utilized in various research applications, including the development of modified oligonucleotides and studies in gene expression. Its unique structure allows for incorporation into DNA, facilitating the exploration of nucleic acid functionality and stability.
  22. Nucleoside Analog

    Cytidine-5'-triphosphate trisodium is a nucleoside analog that serves as a critical monomer for nucleic acid synthesis. Its primary mechanism involves acting as a substrate for RNA polymerases and kinases, facilitating the incorporation of cytidine into RNA strands. This compound is essential for various applications in molecular biology, including RNA synthesis, enzyme studies, and nucleotide metabolism research.
  23. Nucleoside Analog

    DMTr-2'-O-Me-rU-3'-(D)-DPSE-phosphoramidite is a nucleoside analog designed for use in oligonucleotide synthesis. This phosphoramidite provides a versatile building block for the incorporation of modified ribonucleotides into RNA sequences. Its unique structure enhances stability and functionality, making it suitable for various molecular biology applications, including RNA probing and therapeutic development.
  24. Nucleoside Analog

    5-Hme-CTP is a monomeric nucleoside analog that serves as a substrate for nucleic acid synthesis. This compound is utilized in research applications involving the design and analysis of nucleic acid sequences, enabling the study of various biological processes. Its incorporation into nucleic acids can facilitate investigations into gene expression, replication, and repair mechanisms.
  25. Nucleoside Analog

    DMTr-2'-O-propyl-rU-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite monomer facilitates the incorporation of modified uridine residues, enhancing the stability and functionality of oligonucleotides. It serves as a valuable tool in the fields of oligonucleotide chemistry and molecular biology research.
  26. Purine Nucleoside Analog

    2’-Deoxy-2’-iodouridine, also known as 2’-iodo-2’-deoxyuridine, is a purine nucleoside analog that serves as an important tool in cancer research. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. It is valuable for studies aimed at elucidating the molecular pathways involved in cancer cell growth and survival.
  27. Nucleoside Analog

    4'-Fluorouridine triphosphate (4'-F-UTP) is a nucleoside analog that serves as a substrate for RNA synthesis. It incorporates into RNA molecules, allowing for the study of RNA behavior and function. This reagent is valuable in research applications such as exploring RNA modification, gene expression, and the mechanism of action of antiviral compounds.
  28. Nucleoside Analog

    3'-O-TBDMS-2'-dC(Bz) is a nucleoside analog that serves as a key monomeric substrate for nucleic acid synthesis. This compound is utilized in the construction of oligonucleotides, enabling studies in genetic engineering, molecular biology, and therapeutic development. Its unique structural features facilitate incorporation into DNA and RNA sequences, making it a valuable reagent for researchers in the field of nucleic acid chemistry.
  29. Nucleoside Analog

    2'-O-MOE-GMP is a nucleoside analog that serves as a key building block in the synthesis of oligonucleotides. Its unique structural modifications enhance stability and bioavailability of oligonucleotides, making it valuable for various applications in molecular biology, including antisense therapy and RNA interference studies. This compound is instrumental in advancing research in gene expression and regulation.
  30. Nucleoside Analog

    Thiol-modifier C6 S-S CE phosphoramidite is a synthetic nucleoside analog designed for the modification of oligonucleotides. This reagent facilitates the introduction of thiol groups into nucleic acids, enabling the formation of disulfide bonds, which can stabilize oligonucleotide structures and enhance their biological properties. Its primary applications include the synthesis of labeled or modified oligonucleotides for use in molecular biology and genetic research.
  31. Nucleoside Analog

    3'-O-TBDMS-2'-F-dG(iBu) is a nucleoside analog designed for use in nucleic acid synthesis. This compound features a 3'-TBDMS protective group and a 2'-fluorine substitution, enhancing its stability and reactivity in various synthetic protocols. It is instrumental in advancing research in fields such as oligonucleotide chemistry and genetic engineering.
  32. Nucleoside Analog

    DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog designed for incorporation into oligonucleotides during DNA synthesis. This compound serves as a phosphoramidite monomer, providing a stable building block for generating modified nucleic acids. Its unique structural features facilitate the development of oligonucleotide-based probes and therapeutics, making it valuable for applications in molecular biology and genetic research.
  33. Nucleoside Analog

    2′-OMe-GDP is a nucleoside analog that serves as a valuable precursor in the synthesis of modified oligonucleotides. This compound is designed to enhance the stability and binding affinity of nucleic acids, making it useful for various applications in molecular biology and genetic research. Its incorporation into oligonucleotides can facilitate studies involving gene expression, RNA interference, and antisense therapies.
  34. Nucleoside Analog

    N4-Bz-5-Me-DMT-2'-O-MOE-Cr is a nucleoside analog featuring a dimethoxytrityl (DMT) protection group. It is primarily utilized in the synthesis of nucleic acids, serving as a crucial building block for the development of RNA and DNA sequences. This compound provides enhanced stability and compatibility in various biochemical applications, facilitating efficient oligonucleotide synthesis for research in genomics, molecular biology, and therapeutic development.
  35. Nucleoside Analog

    6-Palmitamidohexyl CE phosphoramidite is a nucleoside analog that serves as a monomeric precursor for the synthesis of nucleic acids. This reagent plays a critical role in the preparation of oligonucleotides, facilitating studies in gene expression, molecular diagnostics, and therapeutic applications. Its unique structural properties enable the incorporation of hydrophobic moieties into nucleic acid sequences, contributing to the development of novel nucleic acid-based technologies.
  36. Nucleoside Analog

    Cy3-dUTP is a nucleoside analog that serves as a valuable building block for the synthesis of nucleic acids. This fluorescently tagged nucleotide enables the incorporation of Cy3 into DNA during polymerization, facilitating visualization and study of nucleic acid interactions. Its applications include use in fluorescence microscopy, in situ hybridization, and other molecular biology techniques requiring detection of nucleic acids.
  37. Nucleoside Analog

    2'-F-AMP is a nucleoside analog that serves as a building block for the synthesis of oligonucleotides. Its fluorinated modification enhances thermal stability and hybridization properties, making it valuable for various molecular biology applications. This compound is utilized in the development of DNA and RNA-based therapeutics, as well as in the study of nucleic acid interactions and enzymatic processes.
  38. Nucleoside Analog

    2'-F-UMP is a nucleoside analog that serves as a building block for the synthesis of modified oligonucleotides. Its incorporation into nucleic acid sequences can enhance stability and provide unique properties for various biochemical assays. This compound is valuable in the fields of genetic research, therapeutic development, and molecular biology applications.
  39. Nucleoside Analog

    (2'OMe-5'p-A)pG is a nucleoside analog that serves as a key component in the synthesis of modified nucleic acids. This compound features a 2'-O-methyl modification, enhancing its stability and cellular uptake. It is widely utilized in research applications involving RNA synthesis, oligonucleotide design, and developing therapeutic agents targeting nucleic acids.
  40. Nucleoside Analog

    2'-F-ADP is a nucleoside analog that acts as a building block for oligonucleotide synthesis. Its structural modification enhances the stability and binding affinity of oligonucleotides, making it a valuable tool in molecular biology and genetic engineering research. 2'-F-ADP is utilized for the development of therapeutic oligonucleotides and for studies involving RNA interactions.
  41. Nucleoside Analog

    Fluorescein-12-UTP is a nucleoside analog that serves as a fluorescent label for RNA synthesis. Its primary application lies in the incorporation into RNA transcripts during in vitro transcription, allowing for the visualization and tracking of RNA molecules. This reagent is widely used in studies involving RNA localization, expression analysis, and other molecular biology applications.
  42. Nucleoside Analog

    DMTr-2',2'-diFluoro-dA(Bz)-3'-CE-phosphoramidite is a nucleoside analog utilized as a key monomer in oligonucleotide synthesis. This compound exhibits unique properties due to the presence of di-fluorinated modifications, enhancing the stability and affinity of nucleic acids. It serves as an essential building block for the development of modified oligonucleotides in various research applications, including gene therapy and molecular diagnostics.
  43. Nucleoside Analog

    Reverse abasic phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This compound serves as a monomeric raw material, facilitating the incorporation of abasic sites into oligonucleotides. Its unique properties make it valuable for studying the biochemical effects of abasic sites in DNA and RNA, enabling research in fields such as molecular biology and genetics.
  44. Nucleoside Analog

    DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog primarily used as a monomer for nucleic acid synthesis. This compound facilitates the incorporation of modified nucleotides into oligonucleotide sequences, allowing researchers to study the structural and functional properties of nucleic acids. Its unique modifications enhance stability and binding characteristics, making it valuable in various applications, including antisense research, gene therapy, and RNA interference studies.
  45. Nucleoside Analog

    2′-O-MOE-CMP is a nucleotide analog specifically designed for oligonucleotide synthesis. This compound functions by enhancing the stability and affinity of nucleic acid constructs, making it useful in various molecular biology applications. Its incorporation into oligonucleotides can improve resistance to nucleases and enhance binding properties, facilitating research in gene expression and antisense oligonucleotides.
  46. Nucleoside Analog

    2'-O-Propargyl-rC(Ac) is a nucleoside analog that serves as a versatile monomer for nucleic acid synthesis. Its propargyl group facilitates various chemical modifications, enhancing the structural diversity of RNA molecules. This compound is valuable for applications in RNA research, including the development of RNA probes and therapeutic oligonucleotides.
  47. Nucleoside Analog

    DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite serves as a monomeric building block, enabling the incorporation of modified nucleotides into oligonucleotides. Its application extends to various research areas, including gene delivery and RNA therapeutics development.
  48. Nucleoside Analog

    DMTr-2'-O-propyl-rG(iBu)-3'-CE-phosphoramidite is a nucleoside analog specifically designed for oligonucleotide synthesis. This phosphoramidite derivative enables the incorporation of modified guanine residues into nucleic acid sequences, enhancing their properties for various research applications. It is particularly valuable for studies involving antisense oligonucleotides, RNA interference, and the development of nucleic acid-based therapeutics.
  49. Nucleoside Analog

    N2-Isobutyryl-2'-O,4'-C-methyleneguanosine is a nucleoside analog designed for use in nucleic acid synthesis. This compound features a unique modified structure that enhances its stability and incorporation into RNA sequences, making it an essential reagent for studies in molecular biology and genetic engineering. Its applications extend to investigating RNA function, structure, and the development of novel therapeutics.
  50. Nucleoside Analog

    DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog that serves as a key building block for nucleic acid synthesis. This compound is designed to facilitate the incorporation of modified nucleotides into oligonucleotide sequences, enhancing stability and specificity. Its applications include the development of antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutics, making it valuable for research in gene regulation and molecular biology.

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