Catalog No.
Product Name
Application
Product Information
Citations
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Nucleoside Analog
5'-O-DMTr-2'-O-Me-rA is a nucleoside analog that serves as a versatile building block for nucleic acid synthesis. Its unique chemical modifications enhance stability and efficacy in various biochemical applications. This compound is instrumental in the development of modified oligonucleotides, enabling advancements in RNA therapeutics and molecular biology research. -
Nucleoside Analog
N-Butyl molnupiravir is a nucleoside analog that serves as a crucial building block for nucleic acid synthesis. This compound exhibits antiviral properties and has potential applications in virology research, particularly in the development of therapeutics against RNA viruses. Its modification allows for enhanced stability and effectiveness in various experimental settings. -
Nucleoside Analog
SPS ATP is a nucleoside analog that serves as a critical monomeric substrate in nucleic acid synthesis. Its incorporation into RNA and DNA strands enables the study of nucleic acid structure and function. This reagent is essential for applications in molecular biology, including the development of RNA therapies and the exploration of genetic mechanisms. -
Purine Nucleoside Analog
5-Ethyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in the treatment of indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for research applications focusing on cancer therapy and the understanding of cancer cell metabolism. -
Nucleoside Analog
iBu-dG (N2-Isobutyryl-2'-deoxyguanosine) is a nucleoside analog targeting DNA synthesis. It serves as a key building block for the production of oligoribonucleotides, facilitating research in molecular biology and genetic engineering. iBu-dG is valuable for studies involving nucleotide modification and nucleic acid structures. -
Nucleoside Analog
DMTr-2'-O-C22-rU-3'-CE-phosphoramidite is a nucleoside analog designed for the efficient synthesis of oligonucleotides. This compound serves as a key building block in the construction of RNA sequences, enabling studies in gene expression, RNA interference, and other nucleic acid-based research applications. Its unique 2'-O modification enhances stability and binding properties, making it valuable for various experimental designs in molecular biology. -
Nucleoside Antimetabolite/Analog
2'-O-(2-Methoxyethyl)-uridine is a nucleoside analog that acts as an antimetabolite, specifically targeting RNA synthesis. This synthetic compound exhibits significant potential in the development of chemotherapeutic agents, making it a valuable tool for research in cancer therapeutics and RNA-related studies. Its structural modifications enhance stability and bioavailability, offering insights into nucleoside pharmacology and mechanism of action. -
Purine Nucleoside Analog
5'-Deoxy-5'-iodouridine is a purine nucleoside analog known for its antitumor activity against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and induction of apoptosis, making it a valuable compound in cancer research. This reagent is applicable in studies focused on the mechanisms of tumor cell proliferation and therapeutic resistance. -
Adenosine Analog
DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenosine analog designed for use in oligonucleotide synthesis. This compound functions as a building block for the incorporation of 2'-O-methyl modifications into RNA sequences. Its primary biological activity enables researchers to explore the effects of modifications on RNA stability, structure, and function, making it valuable for studies in molecular biology and therapeutic development. -
Purine Nucleoside Analog
7’-OH-N-trityl morpholinothymine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis, making it valuable in cancer research. Its application in studies focusing on nucleoside metabolism and tumor biology provides essential insights into therapeutic strategies for lymphoid cancers. -
Purine Nucleoside Analog
2-Hydrazinyl-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanism primarily involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for research aimed at understanding and treating various cancers. This reagent is suitable for studies focused on cancer biology and the development of novel therapeutic strategies. -
Nucleoside Analogue
2,3-O-Isopropylidene-D-ribonolactone is a nucleoside analogue that serves as an acetonide derivative of D-ribonolactone. It is primarily utilized as an intermediate in organic synthesis, formed through the acid-catalyzed acetalization of D-ribonolactone with acetone. This compound plays a critical role in the production of 1,5-dideoxy-1,5-imino-D-ribitol and 1,5-dideoxy-1,5-imino-L-arabinitol, making it valuable for various biochemical applications and research endeavors. -
Purine Nucleoside Analog
5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog that targets DNA synthesis pathways. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The compound's mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and drug development. -
Nucleoside Analog
2′,3′-Di-O-acetylguanosine is a nucleoside analog that mimics natural guanosine. It exhibits potential as an antiviral agent and is utilized in biochemical research to study nucleoside metabolism and cellular processes. This compound is relevant for exploring mechanisms of RNA synthesis and functions, making it a valuable tool in molecular biology and therapeutic development research. -
Adenosine Analog
N-Benzoyl-5'-O-dmtr-2'-O-(2-methoxyethyl)-adenosine is an adenosine analog that primarily targets adenosine receptors. It exhibits significant vasodilatory effects by relaxing smooth muscle and has demonstrated potential in inhibiting cancer progression. This compound is valuable in biomedical research, particularly in studies focused on cardiovascular health and cancer therapy. -
Purine Nucleoside Analog
2'-Deoxyisoguanosine is a purine nucleoside analog that demonstrates potential inhibitory effects on tumor cell growth. It acts by targeting telomerase, a critical enzyme for cellular immortality in cancer cells. Although exhibiting low potency and specificity, it serves as a valuable tool for research in cancer biology and the study of telomerase function. -
Purine Nucleoside Analog
3’-O-t-Bulyldimethylsilylthymidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound operates primarily through the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. Its unique mechanisms make it a valuable tool for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
Methyl 2-deoxy-3,5-di-O-toluoyl-D-ribofuranoside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. Its ability to mimic natural nucleosides allows for the exploration of therapeutic strategies targeting tumor cells. -
Purine Nucleoside Analog
8-Methyl-2’-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology. This compound is suitable for studies aimed at exploring therapeutic strategies involving purine metabolism and nucleoside analogs. -
Nucleoside Antimetabolite/Analog
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is a nucleoside antimetabolite and analog that serves as a valuable intermediate for synthesizing oligodeoxynucleotides with 3'-S-phosphorothiolate linkages. This compound is instrumental in studying enzyme-catalyzed cleavage processes within DNA, aiding in the investigation of nucleic acid interactions and mechanisms. Its structural features enhance its utility in various genetic and molecular biology research applications. -
Purine Nucleoside Analog
N6-Ethyl-2’-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism includes the inhibition of DNA synthesis, which plays a crucial role in inducing apoptosis. This compound is valuable for research applications aimed at investigating cancer biology and developing therapeutic strategies for lymphoid malignancies. -
Purine Nucleoside Analog
5-Iodouridine is a purine nucleoside analog that primarily targets dihydroorotase, exhibiting an inhibition constant (Ki) of 340 µM. This compound has been shown to notably enhance the cytotoxic effects of gamma irradiation. Its applications in research extend to investigating herpes simplex virus type 1 (HSV-1) infection and leukemia, providing valuable insights into therapeutic mechanisms and potential treatment strategies. -
Purine Nucleoside Analog
2’-Chloro-N6-(3-methoxy)benzyl adenosine is a purine nucleoside analog that exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. This compound demonstrates significant biological activity against indolent lymphoid malignancies, making it a valuable tool in cancer research. Its mechanisms of action are beneficial for studies focusing on therapeutic strategies for various malignancies. -
Purine Nucleoside Analog
Adenosine-2-carboxamide is a purine nucleoside analog that primarily targets cellular proliferation pathways. It exhibits significant antitumor activity against indolent lymphoid malignancies through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable research tool for investigating cancer treatment strategies and understanding purine metabolism in cancer cells. -
Purine Nucleoside Analog
9-(2-Deoxy-beta-D-ribofuranosyl)-6-methylpurine is a purine nucleoside analog that primarily targets nucleic acid synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA synthesis and induction of apoptosis. It serves as a valuable tool for research into cancer therapeutics and the development of nucleoside-based treatments. -
Purine Nucleoside Analog
2’,3’-Dideoxy-3’-fluorocytidine is a purine nucleoside analogue that inhibits DNA synthesis, making it a valuable compound in cancer research. This reagent exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and interfering with cellular proliferation. Its application in preclinical studies supports investigations into novel therapeutic strategies for treating various cancers. -
Purine Nucleoside Analog
4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog known for its significant antitumor activity against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound serves as a critical reagent for studies aimed at understanding cellular responses to nucleoside analogs and their potential therapeutic applications in oncology. -
Purine Nucleoside Analog
Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve inhibition of DNA synthesis and the induction of apoptosis. H2dUrd is a valuable reagent for research focused on cancer biology and therapeutic developments targeting nucleoside metabolism. -
Purine Nucleoside Analog
5′-Azido-5′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. As a versatile click chemistry reagent, 5′-Azido-5′-deoxyadenosine contains an azide group that readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds featuring DBCO or BCN moieties, making it suitable for various chemical biology applications. -
Adenosine Analog
3’-O-(2-Methoxyethyl)adenosine is an adenosine analog that primarily functions as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it a valuable tool for oncological research. Its properties enable the exploration of adenosine signaling pathways and may contribute to the development of novel therapeutic strategies in cardiovascular and cancer research. -
Purine Nucleoside Analog
α-Cytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is utilized in studies focused on elucidating the molecular pathways underlying tumorigenesis and developing novel therapeutic strategies. -
Adenosine Analog
9-(β-D-Xylofuranosyl)adenine is an adenosine analog that primarily acts as a vasodilator by targeting adenosine receptors. This compound has demonstrated significant biological activity, including the inhibition of cancer progression. It is particularly useful for researchers exploring the mechanisms of vasodilation and the therapeutic potential of adenosine-related pathways in cancer biology. -
Purine Nucleoside Analog
2-Chloro-9-(beta-D-ribofuranosyl)purine functions as a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. This compound is valuable for research applications focused on cancer treatment and the underlying mechanisms of nucleoside analogs in therapeutic contexts. -
Adenosine Analog
2'-Fluoro-2'-deoxy-ara-A(Bz)-3'-phosphoramidite is an adenosine analog that functions primarily as a smooth muscle vasodilator. This compound demonstrates significant biological activity by potentially inhibiting cancer progression. It is widely utilized in research focused on nucleoside metabolism, therapeutic development, and the exploration of adenosine pathways in various physiological and pathological contexts. -
Purine Nucleoside Analog
2’-Deoxy-5,N4-dimethylcytidine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is useful for studying the molecular pathways involved in tumor cell proliferation and can aid in the development of targeted therapies. -
Purine Nucleoside Analog
DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite is a modified purine nucleoside analog that plays a critical role in the field of cancer research. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. It is a valuable reagent for studies focusing on anticancer mechanisms and the development of therapeutic strategies. -
Purine Nucleoside Analog
Alpha-Guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and induction of apoptosis in cancer cells, making it a valuable reagent for cancer research. This compound can aid in investigations focused on understanding nucleoside metabolism and the development of novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
2’-Deoxy-N3-methylcytidine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is utilized in various studies aimed at understanding its effects on cancer cell proliferation and survival pathways. -
Purine Nucleoside Analog
2-Amino-9-β-D-ribofuranosylpurine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is useful in biochemical research focusing on cancer therapeutics and the exploration of nucleoside analog mechanisms in tumor biology. -
Purine Nucleoside Analog
5-Methoxycarbonyl methyl uridine is a purine nucleoside analog that exhibits significant antitumor activity. It operates through mechanisms including the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for studying indolent lymphoid malignancies. This compound is utilized in cancer research to explore its potential therapeutic effects and understand the underlying molecular pathways. -
Purine Nucleoside Analog
N4-Methyl-2’-O-methyl-cytidine functions as a purine nucleoside analog with significant antitumor activity, particularly effective against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic development. This compound is suitable for studies exploring nucleoside analogs in cancer treatment strategies. -
Nucleoside Analogue
1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose is a nucleoside analogue that acts as a structural mimic of ribonucleosides. This compound exhibits potential antiviral properties and can be utilized in research focused on nucleoside metabolism and the development of antiviral therapeutics. Its unique modifications provide valuable insights for studies involving nucleic acid synthesis and enzymatic interactions in cellular systems. -
Purine Nucleoside Analog
2-Thiothymidine is a purine nucleoside analog with significant antitumor activity specifically targeting indolent lymphoid malignancies. Its primary mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is suitable for studies focused on elucidating mechanisms of tumorigenesis and evaluating therapeutic strategies in lymphoid cancers. -
Adenosine Analog
2'-O-Methyladenosine 5'-monophosphate triethylammonium is an adenosine analog that primarily targets adenosine receptors. It exhibits significant biological activity, functioning as a smooth muscle vasodilator while also demonstrating potential for inhibiting cancer progression. This compound is valuable for research applications focusing on cardiovascular studies and cancer biology. -
Purine Nucleoside Analog
Raluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological effects are primarily mediated through the inhibition of DNA synthesis, leading to cell cycle arrest and the induction of apoptosis. This agent serves as a valuable tool in cancer research, facilitating studies aimed at understanding tumor biology and developing novel therapeutic strategies. -
Purine Nucleoside Analog
5-(Aminomethyl)uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
2′-Bromo-2′-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is commonly utilized in research aimed at understanding cancer biology and developing therapeutic strategies for lymphoid cancers. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-4-thiouridine is a purine nucleoside analogue that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and the development of nucleoside-based therapeutics. -
Nucleoside Analog
DMT-OMe-rA(Bz) is a nucleoside analog that functions by mimicking natural nucleosides, thereby influencing nucleic acid metabolism. This compound exhibits key biological activities such as incorporating into RNA and potentially interfering with RNA polymerase activity. DMT-OMe-rA(Bz) is primarily utilized in research applications focusing on RNA synthesis, gene expression modulation, and the development of antiviral therapeutics. -
Adenosine Analog
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog that serves as a key building block for the synthesis of modified nucleotides. This compound exhibits smooth muscle vasodilatory activity and demonstrates potential in inhibiting cancer progression. Its applications in research include the development of therapeutic agents targeting adenosine pathways and investigations into nucleic acid functionality.
