Fig. 1 · Structure
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3’-O-t-Bulyldimethylsilylthymidine
Purine Nucleoside Analog
3’-O-t-Bulyldimethylsilylthymidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound operates primarily through the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. Its unique mechanisms make it a valuable tool for research in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 40733-27-5 |
| Applications | Purine Nucleoside Analog |
| Formula | C16H28N2O5Si |
| Molecular Weight | 356.49 |
| SMILES | OC[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](N2C(NC(C(C)=C2)=O)=O)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.