Catalog No.
Product Name
Application
Product Information
Citations
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Oligonucleotide
m7GpppUpG is an oligonucleotide that serves as an M7GpppNpG trinucleotide cap analogue. This compound facilitates the synthesis of RNA molecules with either cap 0 or cap 1 structures, making it a valuable tool for studies in RNA biology and a useful reagent in RNA manufacturing applications. Its role in modulating RNA stability and translation further supports its utility in nucleic acid research. -
Purine Nucleoside Analog
3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent in cancer research. This compound is useful for studying tumor biology and evaluating potential therapeutic strategies. -
Purine Nucleoside Analog
1,4-Anhydro-2,3-di-O-isopropylidene-4-thio-D-ribitol is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which leads to the induction of apoptosis in cancer cells. This compound serves as a valuable tool in cancer research, facilitating the study of nucleoside analogs in therapeutic applications. -
Purine Nucleoside Analog
3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it relevant for research on indolent lymphoid malignancies. Its application extends to studying cancer cell proliferation and exploring therapeutic pathways in oncological research. -
Purine Nucleoside Analog
2’,5’-Dideoxyuridine is a purine nucleoside analog that functions primarily by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly in the context of indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and disruption of nucleotide metabolism, making it a valuable tool for research focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
2'-β-C-Methyl inosine is a purine nucleoside analog that selectively targets and inhibits critical pathways in cellular proliferation. This compound exhibits significant antitumor activity, particularly in treating indolent lymphoid malignancies, by interfering with DNA synthesis and promoting apoptosis. Its application in cancer research underscores its potential as a therapeutic agent in oncology studies. -
Purine Nucleoside Analog
5-β-D-Ribofuranosyl-2(1H)-pyridinone is a purine nucleoside analog that demonstrates prominent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer therapeutics and the development of innovative treatments targeting purine metabolism. -
MMP-2 Inhibitor
Homouridine is an uridine analogue that acts as an MMP-2 inhibitor, exhibiting an IC50 of 150 μM for compound I. This compound demonstrates significant biological activity through its ability to inhibit TNF-α binding to the TNF-αR1, making it valuable for research applications focused on inflammatory responses and extracellular matrix remodeling. Homouridine serves as a vital intermediate in the synthesis of MMP-2 inhibitors, facilitating studies in cancer and tissue repair mechanisms. -
Purine Nucleoside Analog
N6-Benzoyl-3’-O-(2-methoxyethyl)adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized to study various aspects of cancer biology and therapeutic strategies targeting purine metabolism. -
Purine Nucleoside Analog
5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog that exerts its biological effects primarily through the inhibition of DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and disruption of nucleic acid metabolism, making it a valuable reagent for cancer research and drug development. -
Purine Nucleoside Analog
2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects primarily involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a useful tool in research applications focused on understanding and developing treatments for various types of cancer. -
Purine Nucleoside Analog
3’-O-MOE-U-2’-phosphoramidite is a purine nucleoside analog that targets cellular pathways involved in nucleic acid metabolism. Its primary biological activity includes the inhibition of DNA synthesis and the induction of apoptosis, making it relevant for research in cancer biology. This reagent is widely utilized in studies focused on antitumor mechanisms, particularly in the context of indolent lymphoid malignancies. -
Nucleoside Metabolite
15H-11,12-EETA is a nucleoside metabolite known for its role in cellular metabolism. This compound has been implicated in various biological processes, including cellular signaling and nucleic acid synthesis. Its application in research facilitates the study of nucleoside metabolism and the exploration of related metabolic pathways in both health and disease contexts. -
Purine Nucleoside Analog
2'-Chloro-N6-(4-methoxy)benzyl adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research. This compound is useful for studying the cellular responses to nucleoside analogs and their potential therapeutic effects in oncology. -
Purine Nucleoside Analog
2-Amino-8-aza-7-deaza-7-iodoguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for investigations into therapeutic strategies for lymphoid cancers and exploring the biochemical pathways involved in tumor cell proliferation. -
Nucleoside Metabolite
3-(Methylseleninyl)-L-alanine is a nucleoside metabolite that serves as a selenium-containing analogue of L-alanine. It plays a role in cellular metabolism, particularly in the synthesis of selenoproteins and antioxidant activity. This reagent is valuable for research involving metabolic pathways, selenium biochemistry, and the study of selenoamino acid derivatives in various biological systems. -
Purine Nucleoside Analog
3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research applications focused on therapeutic development and understanding the underlying mechanisms of tumor progression. This compound serves as an important tool for scientists investigating nucleoside analogs in oncology. -
Purine Nucleoside Analog
2'-Deoxy-8-methylamino-adenosine is a purine nucleoside analog known for its antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications aimed at understanding the therapeutic potential of nucleoside analogs in cancer treatment. -
Purine Nucleoside Analog
2-Amino-N6,N6-dimethyl-2’-deoxy-2’-fluoro-beta-D-arabino-adenosine is a purine nucleoside analog that exhibits significant antitumor activity primarily against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is a valuable tool for research into cancer biology and therapeutic development in oncology. -
Purine Nucleoside Analog
3’-Deoxy-3’,5-difluorocytidine is a purine nucleoside analog that exerts its primary effect by interfering with DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as apoptosis induction and cell cycle disruption. Its unique properties make it a valuable tool for cancer research, particularly in studies focused on DNA replication and cellular responses to genotoxic stress. -
Purine Nucleoside Analog
5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is suitable for research applications aimed at exploring therapeutic strategies in cancer treatment and understanding the molecular pathways involved in tumorigenesis. -
Purine Nucleoside Analog
2'-Deoxy-3',2-anhydrouridine is a purine nucleoside analog recognized for its potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is instrumental for studies focused on the development of novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
TLR7 agonist 11 is a purine nucleoside analog that engages Toll-like receptor 7 (TLR7). This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. -
Purine Nucleoside Analog
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog that effectively inhibits DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis in cancer cells. It serves as a valuable tool for research into mechanisms of cancer therapy and nucleoside metabolism. -
Uridine Analog
5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine is an analog of uridine that targets nucleotide metabolism. It exhibits potential antiepileptic properties, making it a valuable tool for studying anticonvulsant and anxiolytic effects. This compound may also facilitate the development of novel antihypertensive agents, enhancing research in therapeutic applications related to epilepsy and hypertension. -
Nucleotide Analog
3′-Phenylcarbamate-UTP is a nucleotide analog derived from uridine triphosphate (UTP) through phenylcarbamate modification. This compound can serve as a substrate for RNA polymerases, facilitating studies in RNA synthesis and turnover. Its unique structural modifications make it a valuable tool in exploring nucleotide interactions and the effects of chemical modifications on nucleic acid biochemistry. Researchers may utilize 3′-Phenylcarbamate-UTP in various applications, including the development of RNA-based therapeutics and the investigation of ribonucleotide metabolism. -
Purine Nucleoside Analog
2'-O-Methyl-N2,N2-dimethyl-guanosine is a purine nucleoside analog that primarily targets nucleic acid synthesis. It exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it valuable for research in cancer therapeutics and relevant biochemical studies. -
Guanosine Analog
N2-iso-Butyroyl-3’-O-methylguanosine is a guanosine analog that targets immune pathways. It exhibits immunostimulatory activity and has been shown to induce type I interferons in various animal models, thereby exerting antiviral effects. The efficacy of this compound is linked to the activation of Toll-like receptor 7 (TLR7), making it a valuable tool for research in immunology and antiviral therapies. -
Nucleoside Analog
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate (2'-Fluoro dATP) is a nucleoside analog that serves as a substrate for DNA synthesis. This compound incorporates a fluorine atom at the 2' position, enhancing its stability and resistance to degradation by nucleases. It is widely utilized in various applications, including in vitro DNA synthesis, molecular cloning, and the study of nucleotide metabolism. -
Adenosine Analog
N6-Benzoyl-9-β-D-arabinofuranosyladenine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and demonstrates potential in inhibiting cancer progression. It serves as a valuable tool in studies focused on cardiovascular research and oncology, enabling researchers to explore the therapeutic implications of adenosine signaling pathways. -
Purine Nucleoside Analog
2-Deoxy-2’-fluoroisocytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent in cancer research and therapeutic development. This compound serves as an important tool for studies related to cancer biology and potential treatment strategies. -
Purine Nucleoside Analog
8-Allyloxyguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biochemical mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable research tool for studying the therapeutic potential of nucleoside analogs in oncology. -
Purine Nucleoside Analog
5’-O-DMTr-2’-OMeU-methyl phosphonamidite is a purine nucleoside analog that effectively targets DNA synthesis to exert antitumor activity. This compound induces apoptosis and demonstrates potential in treating indolent lymphoid malignancies, making it a valuable tool for cancer research. It is applicable in the design and synthesis of therapeutic oligonucleotides and other nucleic acid-based applications. -
Purine Nucleoside Analog
2’-Deoxy-2’-fluoro-N3-(2S)-(2-amino-3-carbonyl] propyl-beta-D-arabinouridine is a purine nucleoside analog that exerts its biological activity through the inhibition of DNA synthesis. This compound demonstrates significant antitumor effects, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleic acid metabolism. Its applications in cancer research make it a valuable tool for investigating therapeutic strategies and understanding the mechanistic pathways involved in tumorigenesis. -
Purine Nucleoside Analog
5’(R)-C-Methyl-2-thiouridine is a purine nucleoside analogue that exerts its biological effects primarily through the inhibition of DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. -
Hypoxanthine Analog
2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog that serves as a vital tool in chemical biology research. This compound exhibits notable anti-inflammatory properties and functions as a potential endogenous inhibitor of poly(ADP-ribose) polymerase (PARP), contributing to cytoprotection by restraining PARP activity and preventing peroxynitrite-induced mitochondrial depolarization. Additionally, its role as a hypoxia indicator makes it valuable for studies involving cellular stress responses and metabolic conditions. -
Uridine Analog
5-Naphthyl-beta-methylaminocarbony-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine is a uridine analog with potential antiepileptic properties. This compound serves as a valuable tool for investigating anticonvulsant and anxiolytic activities and contributes to the development of novel antihypertensive agents. It is particularly relevant for studies focused on neuromodulation and cardiovascular regulation. -
Purine Nucleoside Analog
N1-Propargylpseudouridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and induction of apoptosis, contributing to its efficacy in cancer research. Additionally, N1-Propargylpseudouridine functions as a click chemistry reagent, possessing an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various biochemical applications. -
Adenosine Analog
8-Allylthioadenosine is an adenosine analog that primarily targets adenosine receptors. It demonstrates smooth muscle vasodilatory effects and has been implicated in inhibiting cancer progression, making it a valuable compound for oncology research. Its utility extends to studies involving vascular biology and the modulation of cellular signaling pathways. -
Purine Nucleoside Analog
5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool in cancer research, aiding in the exploration of therapeutic strategies targeting nucleic acid metabolism and cellular proliferation. -
Volatile Compound
(3Z,6Z)-Nonadienal is a volatile compound known for its distinctive marine aroma, reminiscent of oysters. Isolated from the oyster leaf (Mertensia maritima), this compound is utilized in flavor research and sensory analysis. Its unique scent profile makes it an important subject of study in the fields of food science and olfactory research. -
Adenosine Analog
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analog with significant biological activity. This compound primarily acts as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. Research applications include exploring mechanisms of vasodilation and investigating therapeutic strategies in oncology. -
Purine Nucleoside Analog
Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is a purine nucleoside analog that functions primarily by interfering with DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the induction of apoptosis. It serves as a valuable tool for research in cancer biology and therapeutic development. -
Anticancer Agent
DFP-11207 is an orally active fluoropyrimidine cytotoxic agent designed to target and enhance the pharmacological activity of 5-fluorouracil (5-FU). It functions as a pro-drug that incorporates a reversible dihydropyrimidine dehydrogenase (DPD) inhibitor and a potent orotate phosphoribosyltransferase (OPRT) inhibitor, which together mitigate gastrointestinal and myelosuppressive toxicities associated with traditional 5-FU therapy. DFP-11207 is primarily utilized in cancer research, providing insights into more effective and safer chemotherapeutic strategies. -
Purine Nucleoside Analog
N4-Desmethyl wyosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding and developing therapies for various types of hematological cancers. -
Purine Nucleoside Analog
2',3'-Bis(O-(t-butyldimethylsilyl)-5-methoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. Its unique structure enhances cellular uptake and stability, facilitating studies in nucleoside metabolism and targeted cancer therapies. -
Nucleoside Metabolite
Vulpecholic acid is a nucleoside metabolite that plays a crucial role in cellular metabolism. It is involved in the regulation of nucleoside signaling pathways, making it a valuable compound for studying metabolic processes and cellular function. This reagent is suitable for various research applications, including investigations into nucleoside metabolism and its implications in diseases. -
Purine Nucleoside Analog
2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, which are crucial mechanisms in cancer treatment. Its efficacy in targeting specific cancer pathways makes it a valuable reagent for researchers studying tumor biology and potential therapeutic interventions. -
Nucleoside Metabolite
(3S,5S)-3,5-Diaminohexanoate (3S,5S-DAH) is a nucleoside metabolite that plays a critical role in cellular processes. Its primary mechanism involves the modulation of nucleoside metabolism, contributing to various biochemical pathways. This compound is valuable for research applications focused on nucleoside biosynthesis, metabolic regulation, and related therapeutic areas. -
Uridine Analog
2'-Deoxy-2'-fluoro-N3-(n-dodecyl)-beta-D-arabinouridine is a uridine analog primarily explored for its anticonvulsant and anxiolytic properties. This compound may serve as a valuable tool in the investigation of antiepileptic mechanisms and the development of new antihypertensive therapies. Its structural modifications allow for enhanced interactions within various biological pathways, making it a significant asset for chemical research in pharmacology and therapeutic applications.
